The 2023 MDPI Annual Report has
been released!
 
14 pages, 5419 KiB  
Article
Evaluation of Sedimentary Characteristics of the Chang 9 Oil Layer Formation in the Yanchang Formation, Ordos Basin
by Xuelin Qiu and Yaning Wang
Appl. Sci. 2024, 14(10), 4035; https://doi.org/10.3390/app14104035 (registering DOI) - 9 May 2024
Abstract
Shallow-water deltas are a subject of sedimentary research and represent a significant target for oil and gas exploration. The Yanchang Formation of the Triassic in the Ordos Basin comprises numerous shallow-water delta blocks. This paper addresses the core issues pertaining to the sedimentary [...] Read more.
Shallow-water deltas are a subject of sedimentary research and represent a significant target for oil and gas exploration. The Yanchang Formation of the Triassic in the Ordos Basin comprises numerous shallow-water delta blocks. This paper addresses the core issues pertaining to the sedimentary facies, sedimentary characteristics and sand body distribution of the Chang 9 oil layer formation of the Upper Triassic in the Ordos Basin. Guided by the relevant theories and methods of contemporary sedimentology and sedimentary geology, the reservoir characteristics are described and studied in detail through ordinary thin sections, cast thin sections, graphical representations of particle size and scanning electron microscopy experiments. The experimental results indicate that the porosity in the study area ranges from 3% to 12% and that the permeability is between 0 and 1.5 × 10−3 μm2, which is consistent with classification as an ultra-low-porosity and ultra-low-permeability reservoir. The Chang 9 sandstone is composed of feldspar sandstone and lithic feldspar sandstone. The average content of quartz is low, at less than 31%, while the average content of feldspar is high, at more than 34%. The average content of rock debris is between 10% and 20%. Therefore, the compositional maturity of the Chang 9 sand body is generally low. The particle size distribution exhibits a positive deviation, indicating that the sediments in the sand body are primarily coarse-grained components. The kurtosis of the particle size–frequency curve is observed to vary from flat to very sharp. The Chang 91 lake is classified as a shore shallow lake with basin subsidence and lake transgression. The Chang 9 period saw the development of the Chang 91 sedimentary facies into a semi-deep lake–deep lake environment. The vertical structural style of the Chang 9 oil layer formation in the basin can be roughly summarized into three basic structural types: the sedimentary structures observed in the area include box-shaped upward thinning, bell-shaped upward thinning and funnel-shaped upward thickening. The delta front area in Chang 9 is notable for its size and the prevalence of underwater distributary channel microfacies. The sand body distribution is stable, with sand layer thicknesses ranging from 15 to 30 m. The evaluation and summary of the sedimentary characteristics of the Chang 9 oil layer formation provide a geological basis for future exploration and development in the study area. Full article
(This article belongs to the Section Earth Sciences)
Show Figures

Figure 1

12 pages, 245 KiB  
Article
The Cost Reduction Analysis of Green Hydrogen Production from Coal Mine Underground Water for Circular Economy
by Małgorzata Magdziarczyk, Andrzej Chmiela, Roman Dychkovskyi and Adam Smoliński
Energies 2024, 17(10), 2289; https://doi.org/10.3390/en17102289 (registering DOI) - 9 May 2024
Abstract
The novelty of the paper is the analysis of the possibilities of reducing the operating costs of a mine water pumping station in an abandoned coal mine. To meet the energy needs of the pumping station and reduce the carbon footprint, “green” energy [...] Read more.
The novelty of the paper is the analysis of the possibilities of reducing the operating costs of a mine water pumping station in an abandoned coal mine. To meet the energy needs of the pumping station and reduce the carbon footprint, “green” energy from a photovoltaic farm was used. Surplus green energy generated during peak production is stored in the form of green hydrogen from the water electrolysis process. Rainwater and process water are still underutilized sources for increasing water resources and reducing water stress in the European Union. The article presents the possibilities of using these waters, after purification, in the production of green hydrogen by electrolysis. The article also presents three variants that ensure the energy self-sufficiency of the proposed concepts of operation of the pumping station. Full article
(This article belongs to the Special Issue Bioenergy Economics: Analysis, Modeling and Application)
17 pages, 14934 KiB  
Article
Exploring the Relationship between the Dynamics of the Urban–Rural Interface and Regional Development in a Post-Socialist Transition
by Ioan Ianoș, Radu-Matei Cocheci and Alexandru-Ionuț Petrișor
Urban Sci. 2024, 8(2), 47; https://doi.org/10.3390/urbansci8020047 (registering DOI) - 9 May 2024
Abstract
This study offers, by an empirical analysis, another perspective on post-socialist development, highlighting the role of the urban–rural interface in regional dynamics. The current literature on the relationships between both issues is not too rich and our paper analyzes the relationships between core [...] Read more.
This study offers, by an empirical analysis, another perspective on post-socialist development, highlighting the role of the urban–rural interface in regional dynamics. The current literature on the relationships between both issues is not too rich and our paper analyzes the relationships between core cities, their peri-urban areas, and their regions, through a comparative overview of their growth over the last three decades. Romania, as a special case study for a contradictory transition, due to the great step from a drastic dictatorial regime to a democracy and a market economy, is a good example to test these complex relationships. Considering the new development trend at the urban–rural interfaces, our key idea was to depict their contribution to regional development (NUTS 3) compared to city cores. The second question was how this differentiated contribution can be measured, using the simplest tool. The starting point was the fact that population dynamics reflect all changes in the city core and at the urban–rural interface, and less so at a regional level. Consequently, we selected the dynamics of the number of inhabitants for the first two, as well as the dynamics of GDP per capita at the regional level. We found higher and significant correlations between GDP per capita and urban–rural interfaces, but no significant correlations in the case of city cores. Our conclusion is that, in the transition period, the dynamics of urban–rural interfaces influenced more regional development dynamics, than those of city cores. This means that urban–rural interfaces amplify the development coming from cities, adding their own contribution and then dissipating it regionally. Future research should identify what the urban–rural interface offers to regions, in addition to the city core. Full article
(This article belongs to the Special Issue Rural–Urban Transformation and Regional Development)
Show Figures

Figure 1

12 pages, 4155 KiB  
Article
Clap-and-Fling Mechanism of Climbing-Flight Coccinella Septempunctata
by Lili Yang, Huichao Deng, Kai Hu and Xilun Ding
Biomimetics 2024, 9(5), 282; https://doi.org/10.3390/biomimetics9050282 (registering DOI) - 9 May 2024
Abstract
Previous studies on the clap–fling mechanism have predominantly focused on the initial downward and forward phases of flight in miniature insects, either during hovering or forward flight. However, this study presents the first comprehensive kinematic data of Coccinella septempunctata during climbing flight. It [...] Read more.
Previous studies on the clap–fling mechanism have predominantly focused on the initial downward and forward phases of flight in miniature insects, either during hovering or forward flight. However, this study presents the first comprehensive kinematic data of Coccinella septempunctata during climbing flight. It reveals, for the first time, that a clap-and-fling mechanism occurs during the initial upward and backward phase of the hind wings’ motion. This discovery addresses the previously limited understanding of the clap-and-fling mechanism by demonstrating that, during the clap motion, the leading edges of beetle’s wings come into proximity to form a figure-eight shape before rotating around their trailing edge to open into a “V” shape. By employing numerical solutions to solve Navier–Stokes (N-S) equations, we simulated both single hind wings’ and double hind wings’ aerodynamic conditions. Our findings demonstrate that this fling mechanism not only significantly enhances the lift coefficient by approximately 9.65% but also reduces the drag coefficient by about 1.7%, indicating an extension of the applicability range of this clap-and-fling mechanism beyond minute insect flight. Consequently, these insights into insect flight mechanics deepen our understanding of their biological characteristics and inspire advancements in robotics and biomimetics. Full article
Show Figures

Figure 1

15 pages, 5452 KiB  
Article
Suppression of Initial Charging Torque for Electric Drive-Reconfigured On-Board Charger
by Yang Xiao, Kangwei Wang, Zhi Geng, Kai Ni, Mingdi Fan and Yong Yang
World Electr. Veh. J. 2024, 15(5), 207; https://doi.org/10.3390/wevj15050207 (registering DOI) - 9 May 2024
Abstract
This paper presents a new electric drive-reconfigured on-board charger and initial electromagnetic torque suppression method. This proposed reconfigured on-board charger does not need many components added to the original electric drive system: only a connector is needed, which is easy to add. Specifically, [...] Read more.
This paper presents a new electric drive-reconfigured on-board charger and initial electromagnetic torque suppression method. This proposed reconfigured on-board charger does not need many components added to the original electric drive system: only a connector is needed, which is easy to add. Specifically, the inverter for propulsion is reconfigured as a buck chopper and a conduction path to match the reconfigured windings. Two of the machine phase windings serve as inductors, while the third phase winding is reutilized as a common-mode inductor. In addition, the initial charging torque is generated at the outset of the charging process, which may cause an instant shock or even rotational movement. In order to prevent vehicle movement, the reason for the charging torque and suppression method were analyzed. Further, predictive control of the model based on mutual inductance analysis was adopted, where the charging torque was directly used as a control object in the cost function. Finally, experimental performances were applied to verify the proposed reconfigured on-board charger under constant current and constant voltage charging. Full article
Show Figures

Figure 1

32 pages, 3664 KiB  
Article
Research on Bidirectional Multi-Span Feature Pyramid and Key Feature Capture Object Detection Network
by Heng Zhang, Faming Shao, Xiaohui He, Dewei Zhao, Zihan Zhang and Tao Zhang
Drones 2024, 8(5), 189; https://doi.org/10.3390/drones8050189 (registering DOI) - 9 May 2024
Abstract
UAV remote sensing (RS) image object detection is a very valuable and challenging technology. This article discusses the importance of key features and proposes an object detection network (URSNet) based on a bidirectional multi-span feature pyramid and key feature capture mechanism. Firstly, a [...] Read more.
UAV remote sensing (RS) image object detection is a very valuable and challenging technology. This article discusses the importance of key features and proposes an object detection network (URSNet) based on a bidirectional multi-span feature pyramid and key feature capture mechanism. Firstly, a bidirectional multi-span feature pyramid (BMSFPN) is constructed. In the process of bidirectional sampling, bicubic interpolation and cross layer fusion are used to filter out image noise and enhance the details of object features. Secondly, the designed feature polarization module (FPM) uses the internal polarization attention mechanism to build a powerful feature representation for classification and regression tasks, making it easier for the network to capture the key object features with more semantic discrimination. In addition, the anchor rotation alignment module (ARAM) further refines the preset anchor frame based on the key regression features extracted by FPM to obtain high-quality rotation anchors with a high matching degree and rich positioning visual information. Finally, the dynamic anchor optimization module (DAOM) is used to improve the ability of feature alignment and positive and negative sample discrimination of the model so that the model can dynamically select the candidate anchor to capture the key regression features so as to further eliminate the deviation between the classification and regression. URSNet has conducted comprehensive ablation and SOTA comparative experiments on challenging RS datasets such as DOTA-V2.0, DIOR and RSOD. The optimal experimental results (87.19% mAP, 108.2 FPS) show that URSNet has efficient and reliable detection performance. Full article
14 pages, 1072 KiB  
Article
Design and Validation of a Computational Thinking Test for Children in the First Grades of Elementary Education
by Jorge Hernán Aristizábal Zapata, Julián Esteban Gutiérrez Posada and Pascual D. Diago
Multimodal Technol. Interact. 2024, 8(5), 39; https://doi.org/10.3390/mti8050039 (registering DOI) - 9 May 2024
Abstract
Computational thinking (CT) has garnered significant interest in both computer science and education sciences as it delineates a set of skills that emerge during the problem-solving process. Consequently, numerous assessment instruments aimed at measuring CT have been developed in the recent years. However, [...] Read more.
Computational thinking (CT) has garnered significant interest in both computer science and education sciences as it delineates a set of skills that emerge during the problem-solving process. Consequently, numerous assessment instruments aimed at measuring CT have been developed in the recent years. However, a scarce part of the existing CT measurement instruments has been dedicated to early school ages, and few have undergone rigorous validation or reliability testing. Therefore, this work introduces a new instrument for measuring CT in the early grades of elementary education: the Computational Thinking Test for Children (CTTC). To this end, in this work, we provide the design and validation of the CTTC, which is constructed around spatial, sequential, and logical thinking and encompasses abstraction, decomposition, pattern recognition, and coding items organized in five question blocks. The validation and standardization process employs the Kuder–Richardson statistic (KR-20) and expert judgment using V-Aiken for consistency. Additionally, item difficulty indices were utilized to gauge the difficulty level of each question in the CTTC. The study concludes that the CTTC demonstrates consistency and suitability for children in the first cycle of primary education (encompassing the first to third grades). Full article
16 pages, 3437 KiB  
Article
Clustering of Wind Speed Time Series as a Tool for Wind Farm Diagnosis
by Ana Alexandra Martins, Daniel C. Vaz, Tiago A. N. Silva, Margarida Cardoso and Alda Carvalho
Math. Comput. Appl. 2024, 29(3), 35; https://doi.org/10.3390/mca29030035 (registering DOI) - 9 May 2024
Abstract
In several industrial fields, environmental and operational data are acquired with numerous purposes, potentially generating a huge quantity of data containing valuable information for management actions. This work proposes a methodology for clustering time series based on the K-medoids algorithm using a convex [...] Read more.
In several industrial fields, environmental and operational data are acquired with numerous purposes, potentially generating a huge quantity of data containing valuable information for management actions. This work proposes a methodology for clustering time series based on the K-medoids algorithm using a convex combination of different time series correlation metrics, the COMB distance. The multidimensional scaling procedure is used to enhance the visualization of the clustering results, and a matrix plot display is proposed as an efficient visualization tool to interpret the COMB distance components. This is a general-purpose methodology that is intended to ease time series interpretation; however, due to the relevance of the field, this study explores the clustering of time series judiciously collected from data of a wind farm located on a complex terrain. Using the COMB distance for wind speed time bands, clustering exposes operational similarities and dissimilarities among neighboring turbines which are influenced by the turbines’ relative positions and terrain features and regarding the direction of oncoming wind. In a significant number of cases, clustering does not coincide with the natural geographic grouping of the turbines. A novel representation of the contributing distances—the COMB distance matrix plot—provides a quick way to compare pairs of time bands (turbines) regarding various features. Full article
Show Figures

Figure 1

19 pages, 2635 KiB  
Article
Driving Domain Classification Based on Kernel Density Estimation of Urban Land Use and Road Network Scaling Models
by Gerrit Brandes, Christian Sieg, Marcel Sander and Roman Henze
Urban Sci. 2024, 8(2), 48; https://doi.org/10.3390/urbansci8020048 (registering DOI) - 9 May 2024
Abstract
Current research on automated driving systems focuses on Level 4 automated driving (AD) in specific operational design Domains (ODD). Measurement data from customer fleet operation are commonly used to extract scenarios and ODD features (road infrastructure, etc.) for the testing of AD functions. [...] Read more.
Current research on automated driving systems focuses on Level 4 automated driving (AD) in specific operational design Domains (ODD). Measurement data from customer fleet operation are commonly used to extract scenarios and ODD features (road infrastructure, etc.) for the testing of AD functions. To ensure data relevance for the vehicle use case, driving domain classification of the data is required. Generally, classification into urban, extra-urban and highway domains provides data with similar ODD features. Highway classification can be implemented using global navigation satellite system coordinates of the driving route, map-matching algorithms, and road classes stored in digital maps. However, the distinction between urban and extra-urban driving domains is more complex, as settlement taxonomies and administrative-level hierarchies are not globally consistent. Therefore, this paper presents a map-based method for driving domain classification. First, potential urban areas (PUA) are identified based on urban land-use density, which is determined based on land-use categories from OpenStreetMap (OSM) and then spatially smoothed by kernel density estimation. Subsequently, two road network scaling models are used to distinguish between urban and extra-urban domains for the PUA. Finally, statistics of ODD feature distribution are analysed for the classified urban and extra-urban areas. Full article
(This article belongs to the Topic Urban Land Use and Spatial Analysis)
19 pages, 2510 KiB  
Article
Design and Characterization of Highly Diffusive Turbine Vanes Suitable for Transonic Rotating Detonation Combustors
by Sergio Grasa and Guillermo Paniagua
Int. J. Turbomach. Propuls. Power 2024, 9(2), 18; https://doi.org/10.3390/ijtpp9020018 (registering DOI) - 9 May 2024
Abstract
In rotating detonation engines the turbine inlet conditions may be transonic with unprecedented unsteady fluctuations. To ensure an acceptable engine performance, the turbine passages must be suited to these conditions. This article focuses on designing and characterizing highly diffusive turbine vanes to operate [...] Read more.
In rotating detonation engines the turbine inlet conditions may be transonic with unprecedented unsteady fluctuations. To ensure an acceptable engine performance, the turbine passages must be suited to these conditions. This article focuses on designing and characterizing highly diffusive turbine vanes to operate at any inlet Mach number up to Mach 1. First, the effect of pressure loss on the starting limit is presented. Afterward, a multi-objective optimization with steady RANS simulations, including the endwall and 3D vane design is performed. Compared to previous research, significant reductions in pressure loss and stator-induced rotor forcing are obtained, with an extended operating range and preserving high flow turning. Finally, the influence of the inlet boundary layer thickness on the vane performance is evaluated, inducing remarkable increases in pressure loss and downstream pressure distortion. Employing an optimization with a thicker inlet boundary layer, specific endwall design recommendations are found, providing a notable improvement in both objective functions. Full article
17 pages, 2537 KiB  
Article
Joint Phase Shift Design and Resource Management for a Non-Orthogonal Multiple Access-Enhanced Internet of Vehicle Assisted by an Intelligent Reflecting Surface-Equipped Unmanned Aerial Vehicle
by Lijuan Wang, Yixin He, Bin Chen, Abual Hassan, Dawei Wang, Lina Yang and Fanghui Huang
Drones 2024, 8(5), 188; https://doi.org/10.3390/drones8050188 (registering DOI) - 9 May 2024
Abstract
This paper integrates intelligent reflecting surfaces (IRS) with unmanned aerial vehicles (UAV) to enhance the transmission performance of the Internet of Vehicles (IoV) through non-orthogonal multiple access (NOMA). It focuses on strengthening the signals from cell edge vehicles (CEVs) to the base station [...] Read more.
This paper integrates intelligent reflecting surfaces (IRS) with unmanned aerial vehicles (UAV) to enhance the transmission performance of the Internet of Vehicles (IoV) through non-orthogonal multiple access (NOMA). It focuses on strengthening the signals from cell edge vehicles (CEVs) to the base station by optimizing the wireless propagation environment via an IRS-equipped UAV. The primary goal is to maximize the sum data rate of CEVs while satisfying the constraint of the successive interference cancellation (SIC) decoding threshold. The challenge lies in the non-convex nature of jointly considering the power control, subcarrier allocation, and phase shift design, making the problem difficult to optimally solve. To address this, the problem is decomposed into two independent subproblems, which are then solved iteratively. Specifically, the optimal phase shift design is achieved using the deep deterministic policy gradient (DDPG) algorithm. Furthermore, the graph theory is applied to determine the subcarrier allocation policy and derive a closed-form solution for optimal power control. Finally, the simulation results show that the proposed joint phase shift and resource management scheme significantly enhances the sum data rate compared to the state-of-the-art schemes, thereby demonstrating the benefits of integrating the IRS-equipped UAV into NOMA-enhanced IoV. Full article
(This article belongs to the Section Drone Communications)
Show Figures

Figure 1

13 pages, 2998 KiB  
Technical Note
Image Quality Assessment Tool for Conventional and Dynamic Magnetic Resonance Imaging Acquisitions
by Katerina Nikiforaki, Ioannis Karatzanis, Aikaterini Dovrou, Maciej Bobowicz, Katarzyna Gwozdziewicz, Oliver Díaz, Manolis Tsiknakis, Dimitrios I. Fotiadis, Karim Lekadir and Kostas Marias
J. Imaging 2024, 10(5), 115; https://doi.org/10.3390/jimaging10050115 (registering DOI) - 9 May 2024
Abstract
Image quality assessment of magnetic resonance imaging (MRI) data is an important factor not only for conventional diagnosis and protocol optimization but also for fairness, trustworthiness, and robustness of artificial intelligence (AI) applications, especially on large heterogeneous datasets. Information on image quality in [...] Read more.
Image quality assessment of magnetic resonance imaging (MRI) data is an important factor not only for conventional diagnosis and protocol optimization but also for fairness, trustworthiness, and robustness of artificial intelligence (AI) applications, especially on large heterogeneous datasets. Information on image quality in multi-centric studies is important to complement the contribution profile from each data node along with quantity information, especially when large variability is expected, and certain acceptance criteria apply. The main goal of this work was to present a tool enabling users to assess image quality based on both subjective criteria as well as objective image quality metrics used to support the decision on image quality based on evidence. The evaluation can be performed on both conventional and dynamic MRI acquisition protocols, while the latter is also checked longitudinally across dynamic series. The assessment provides an overall image quality score and information on the types of artifacts and degrading factors as well as a number of objective metrics for automated evaluation across series (BRISQUE score, Total Variation, PSNR, SSIM, FSIM, MS-SSIM). Moreover, the user can define specific regions of interest (ROIs) to calculate the regional signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR), thus individualizing the quality output to specific use cases, such as tissue-specific contrast or regional noise quantification. Full article
Show Figures

Figure 1

22 pages, 596 KiB  
Review
Unlocking the Potential of Mannosylerythritol Lipids: Properties and Industrial Applications
by Joana Dias de Almeida, Miguel Figueiredo Nascimento, Petar Keković, Frederico Castelo Ferreira and Nuno Torres Faria
Fermentation 2024, 10(5), 246; https://doi.org/10.3390/fermentation10050246 (registering DOI) - 9 May 2024
Abstract
Mannosylerythritol lipids (MELs), one of the most promising biosurfactants (BS), are glycolipids produced by yeasts or fungi, which have great environmental performance and high compatibility with the human body. MELs, besides working as typical surfactants, can form diverse structures when at or above [...] Read more.
Mannosylerythritol lipids (MELs), one of the most promising biosurfactants (BS), are glycolipids produced by yeasts or fungi, which have great environmental performance and high compatibility with the human body. MELs, besides working as typical surfactants, can form diverse structures when at or above the critical aggregation concentration (CAC), reduce the surface tension of water and other solutions, and be stable over a wide range of conditions. Among others, MELs present antimicrobial, antitumor, antioxidant and anti-inflammatory activities and skin and hair repair capacity, which opens possibilities for their use in applications from cosmetics and pharmaceutics to bioremediation and agriculture. However, their market share is still low when compared to other glycolipids, due to their less developed production process and higher production cost. This review gathers information on the potential applications of MELs mentioned in the literature since 1993. Furthermore, it also explores the current strategies being developed to enhance the market presence of MELs, in parallel with the ones developed for rhamnolipids and sophorolipids. Full article
17 pages, 9191 KiB  
Article
Modulating ‘Xinomavro’ (Vitis vinifera L.) Vine Growth and Berry Composition: A Comparative Analysis of Rootstock Effects
by Serafeim Theocharis, Theodoros Gkrimpizis, Christina Karadimou, Anastasios Alatzas, Stefanos Koundouras and Dimitrios Taskos
Horticulturae 2024, 10(5), 490; https://doi.org/10.3390/horticulturae10050490 (registering DOI) - 9 May 2024
Abstract
Rootstocks serve as a strategic tool for grapevine adaptation to specific biotic and abiotic conditions and for managing vine growth, grape yield, and berry composition in commercial vineyards. This study investigates the influences of four different rootstock varieties (101-14 MGt, 3309 C, 110 [...] Read more.
Rootstocks serve as a strategic tool for grapevine adaptation to specific biotic and abiotic conditions and for managing vine growth, grape yield, and berry composition in commercial vineyards. This study investigates the influences of four different rootstock varieties (101-14 MGt, 3309 C, 110 R, and 140 Ru) on the viticultural performance of ‘Xinomavro’ vines, a prominent Greek red winegrape varietal. By conducting a two-year field experiment using various rootstocks, we assessed parameters related to water status, vegetative growth, yield, and berry composition. Our results revealed that rootstock selection has a significant impact on vine development, especially in terms of berry size and the concentrations of secondary metabolites. Principal component analysis confirmed the complex interaction between rootstock vigor and vine productivity. This study underscores the importance of rootstock variety in manipulating grapevine characteristics, particularly for the ‘Xinomavro’ variety, in response to regional climatic conditions. Full article
Show Figures

Figure 1

18 pages, 8152 KiB  
Review
Heart Failure with Mildly Reduced Ejection Fraction—A Phenotype Waiting to Be Explored
by Anugrah Nair, Lukah Q. Tuan, Natasha Jones-Lewis, Deep Chandh Raja, Jenish Shroff and Rajeev Kumar Pathak
J. Cardiovasc. Dev. Dis. 2024, 11(5), 148; https://doi.org/10.3390/jcdd11050148 (registering DOI) - 9 May 2024
Abstract
Heart failure (HF) presents a significant global health challenge recognised by frequent hospitalisation and high mortality rates. The assessment of left ventricular (LV) ejection fraction (EF) plays a crucial role in diagnosing and predicting outcomes in HF, leading to its classification into preserved [...] Read more.
Heart failure (HF) presents a significant global health challenge recognised by frequent hospitalisation and high mortality rates. The assessment of left ventricular (LV) ejection fraction (EF) plays a crucial role in diagnosing and predicting outcomes in HF, leading to its classification into preserved (HFpEF), reduced (HFrEF), and mildly reduced (HFmrEF) EF. HFmrEF shares features of both HFrEF and HFpEF but also exhibits distinct characteristics. Despite advancements, managing HFmrEF remains challenging due to its diverse presentation. Large-scale studies are needed to identify the predictors of clinical outcomes and treatment responses. Utilising biomarkers for phenotyping holds the potential for discovering new treatment targets. Given the uncertainty surrounding optimal management, individualised approaches are imperative for HFmrEF patients. This chapter examines HFmrEF, discusses the rationale for its re-classification, and elucidates HFmrEF’s key attributes. Furthermore, it provides a comprehensive review of current treatment strategies for HFmrEF patients. Full article
(This article belongs to the Section Electrophysiology and Cardiovascular Physiology)
Show Figures

Figure 1

11 pages, 1305 KiB  
Article
Establishment of a Multilocus Sequence Typing Scheme for the Characterization of Avibacterium paragallinarum
by Mengjiao Guo, Yikun Jin, Haonan Wang, Xiaorong Zhang and Yantao Wu
Vet. Sci. 2024, 11(5), 208; https://doi.org/10.3390/vetsci11050208 (registering DOI) - 9 May 2024
Abstract
Infectious coryza is an acute respiratory infection caused by Avibacterium paragallinarum, which is widely distributed throughout the world. However, there is no effective molecular typing scheme to obtain basic knowledge about the Av. paragallinarum population structure. This study aimed to develop a [...] Read more.
Infectious coryza is an acute respiratory infection caused by Avibacterium paragallinarum, which is widely distributed throughout the world. However, there is no effective molecular typing scheme to obtain basic knowledge about the Av. paragallinarum population structure. This study aimed to develop a multilocus sequence typing (MLST) scheme for Av. paragallinarum that allows for the worldwide comparison of sequence data. For this purpose, the genetic variability of 59 Av. paragallinarum strains from different geographical origins and serovars was analyzed to identify correlations. The MLST scheme was developed using seven conserved housekeeping genes, which identified eight STs that clustered all of the strains into three evolutionary branches. The analytical evaluation of the clone group relationship between the STs revealed two clone complexes (CC1 and CC2) and three singletons (ST2, ST5, and ST6). Most of the isolates from China belonged to ST1 and ST3 in CC1. ST8 from Peru and ST7 from North America together formed CC2. Our results showed that the Av. paragallinarum strains isolated from China had a distant genetic relationship with CC2, indicating strong regional specificity. The MLST scheme established in this study can monitor the dynamics and genetic differences of Av. paragallinarum transmission. Full article
(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
Show Figures

Figure 1

13 pages, 1024 KiB  
Article
Seroprevalence of West Nile Virus among Equids in Bulgaria in 2022 and Assessment of Some Risk Factors
by Nikolina Rusenova, Anton Rusenov, Mihail Chervenkov and Ivo Sirakov
Vet. Sci. 2024, 11(5), 209; https://doi.org/10.3390/vetsci11050209 (registering DOI) - 9 May 2024
Abstract
The aim of this study was to analyze the seroprevalence of West Nile virus (WNV) among equids in Bulgaria, confirm the results of a competitive ELISA versus the virus neutralization test (VNT) and investigate some predisposing factors for WNV seropositivity. A total of [...] Read more.
The aim of this study was to analyze the seroprevalence of West Nile virus (WNV) among equids in Bulgaria, confirm the results of a competitive ELISA versus the virus neutralization test (VNT) and investigate some predisposing factors for WNV seropositivity. A total of 378 serum samples from 15 provinces in northern and southern Bulgaria were tested. The samples originated from 314 horses and 64 donkeys, 135 males and 243 females, aged from 1 to 30 years. IgG and IgM antibodies against WNV protein E were detected by ELISA. ELISA-positive samples were additionally tested via VNT for WNV and Usutu virus. Thirty-five samples were WNV-positive by ELISA (9.26% [CI = 6.45–12.88]), of which 15 were confirmed by VNT; hence, the seroprevalence was 3.97% (CI = 2.22–6.55). No virus-neutralizing antibodies to Usutu virus were detected among the 35 WNV-ELISA-positive equids in Bulgaria. When compared with VNT, ELISA showed 100.0% sensitivity and 94.5% specificity. A statistical analysis showed that the risk factors associated with WNV seropositivity were the region (p < 0.0001), altitude of the locality (p < 0.0001), type of housing (p < 0.0001) and breed (p = 0.0365). The results of the study demonstrate, albeit indirectly, that WNV circulates among equids in northern and southern Bulgaria, indicating that they could be suitable sentinel animals for predicting human cases and determining the risk in these areas or regions of the country. Full article
19 pages, 12306 KiB  
Article
Towards Complex Tissues Replication: Multilayer Scaffold Integrating Biomimetic Nanohydroxyapatite/Chitosan Composites
by Barbara Palazzo, Stefania Scialla, Amilcare Barca, Laura Sercia, Daniela Izzo, Francesca Gervaso and Francesca Scalera
Bioengineering 2024, 11(5), 471; https://doi.org/10.3390/bioengineering11050471 (registering DOI) - 9 May 2024
Abstract
This study explores an approach to design and prepare a multilayer scaffold mimicking interstratified natural tissue. This multilayer construct, composed of chitosan matrices with graded nanohydroxyapatite concentrations, was achieved through an in situ biomineralization process applied to individual layers. Three distinct precursor concentrations [...] Read more.
This study explores an approach to design and prepare a multilayer scaffold mimicking interstratified natural tissue. This multilayer construct, composed of chitosan matrices with graded nanohydroxyapatite concentrations, was achieved through an in situ biomineralization process applied to individual layers. Three distinct precursor concentrations were considered, resulting in 10, 20, and 30 wt% nanohydroxyapatite content in each layer. The resulting chitosan/nanohydroxyapatite (Cs/n-HAp) scaffolds, created via freeze-drying, exhibited nanohydroxyapatite nucleation, homogeneous distribution, improved mechanical properties, and good cytocompatibility. The cytocompatibility analysis revealed that the Cs/n-HAp layers presented cell proliferation similar to the control in pure Cs for the samples with 10% n-HAp, indicating good cytocompatibility at this concentration, while no induction of apoptotic death pathways was demonstrated up to a 20 wt% n-Hap concentration. Successful multilayer assembly of Cs and Cs/n-HAp layers highlighted that the proposed approach represents a promising strategy for mimicking multifaceted tissues, such as osteochondral ones. Full article
(This article belongs to the Special Issue Biomaterials for Cartilage and Bone Tissue Engineering)
Show Figures

Figure 1

14 pages, 21843 KiB  
Article
Effect of Polymer and Crosslinker Concentration on Static and Dynamic Gelation Behavior of Phenolic Resin Hydrogel
by Wenjuan Ji, Bei Chang, Haiyang Yu, Yilin Li and Weiqiang Song
Gels 2024, 10(5), 325; https://doi.org/10.3390/gels10050325 (registering DOI) - 9 May 2024
Abstract
The application results of profile control and water plugging technology are highly related to the gelation time and strength of phenolic resin hydrogel. In this work, a hydrogel solution was prepared by fully mixing the prepared polymer solution with a crosslinker. The static [...] Read more.
The application results of profile control and water plugging technology are highly related to the gelation time and strength of phenolic resin hydrogel. In this work, a hydrogel solution was prepared by fully mixing the prepared polymer solution with a crosslinker. The static gelation process of PFR hydrogel in ampoule bottles and porous media was analyzed by changes in the viscosity and residual resistance coefficient. Then, the dynamic gelation of the PFR hydrogel in porous media was tested using a circulating flow device, and the changes in viscosity and injection pressure were analyzed during the dynamic gelation process. Finally, the effects of the polymer concentration and crosslinker concentration on dynamic gelation were analyzed. The initial gelation time and final gelation time in porous media were 1–1.5 times and 1.5–2 times those in ampoule bottles under static conditions, respectively. The initial dynamic gelation time in porous media was 2–2.5 times and 1.5–2 times the initial static gelation times in ampoule bottles and porous media, respectively. The final dynamic gelation time was four times and two times the initial static gelation times in ampoule bottles and porous media, respectively. The production after dynamic gelation in porous media comprised hydrogel aggregates and water fluid, leading to a high injection pressure and low viscosity of the produced liquid. As the concentration of polymer and crosslinker increased, the dynamic gelation time was shortened and the gel strength was increased. In the dynamic gelation process in porous media, the phenol resin hydrogel could migrate deeply, but it was limited by the concentrations of the polymer and crosslinker. The results of subsequent water flooding showed that the polymer hydrogel had a good plugging ability after dynamic gelation. The deep reservoir could only be blocked off in the subsequent water flooding process when the migration of hydrogel happened in the dynamic gelation process. Full article
(This article belongs to the Special Issue Gels for Oil and Gas Industry Applications (2nd Edition))
Show Figures

Figure 1

15 pages, 1104 KiB  
Article
Characterization of Culturable Mycobiome of Newly Excavated Ancient Wooden Vessels from the Archeological Site of Viminacium, Serbia
by Ivana Djokić, Aleksandar Knežević, Željko Savković, Milica Ljaljević Grbić, Ivica Dimkić, Danka Bukvički, Dragana Gavrilović and Nikola Unković
J. Fungi 2024, 10(5), 343; https://doi.org/10.3390/jof10050343 (registering DOI) - 9 May 2024
Abstract
Two ancient wooden vessels, specifically a monoxyle (1st century BCE to 1st century CE) and shipwreck (15th to 17th century CE), were excavated in a well-preserved state east of the confluence of the old Mlava and the Danube rivers (Serbia). The vessels were [...] Read more.
Two ancient wooden vessels, specifically a monoxyle (1st century BCE to 1st century CE) and shipwreck (15th to 17th century CE), were excavated in a well-preserved state east of the confluence of the old Mlava and the Danube rivers (Serbia). The vessels were found in the ground that used to be river sediment and were temporarily stored within the semi-underground exhibition space of Mammoth Park. As part of the pre-conservation investigations, the primary aim of the research presented was to characterize the culturable mycobiomes of two excavated wooden artifacts so that appropriate conservation procedures for alleviating post-excavation fungal infestation could be formulated. Utilizing culture-based methods, a total of 32 fungi from 15 genera were identified, mainly Ascomycota and to a lesser extent Mucoromycota sensu stricto. Soft-rot Ascomycota of genus Penicillium, followed by Aspergillus and Cephalotrichum species, were the most diverse of the isolated fungi. Out of a total of 38 isolates, screened on 7 biodegradation plate assays, 32 (84.21%) demonstrated at least one degradative property. Penicillium solitum had the highest deterioration potential, with a positive reaction in 5 separate plate assays. The obtained results further broaden the limited knowledge on the peculiarities of post-excavation soft-rot decay of archaeological wood and indicate the biochemical mechanisms at the root of post-excavation fungal deterioration. Full article
23 pages, 5523 KiB  
Article
Encapsulation of W/O/W Acerola Emulsion by Spray Drying: Optimization, Release Kinetics, and Storage Stability
by Yen Thi Dang, Hieu Tran and Tuyen Chan Kha
Foods 2024, 13(10), 1463; https://doi.org/10.3390/foods13101463 (registering DOI) - 9 May 2024
Abstract
Acerola (Malpighia emarginata DC.) is a sub-tropical and tropical fruit renowned for its high levels of vitamin C and phenolic compounds, which offer health benefits. This study aimed to optimize the spray drying process by determining the inlet and outlet temperatures using [...] Read more.
Acerola (Malpighia emarginata DC.) is a sub-tropical and tropical fruit renowned for its high levels of vitamin C and phenolic compounds, which offer health benefits. This study aimed to optimize the spray drying process by determining the inlet and outlet temperatures using response surface methodology (RSM) with the central composite design. Additionally, it aimed to evaluate the release kinetics in the hydrophilic food simulation environment and the stability of the resulting powder under various storage temperatures. The RSM method determined the optimal inlet and outlet temperatures as 157 °C and 91 °C, respectively. High-accuracy prediction equations (R2 ≥ 0.88) were developed for moisture content (3.02%), process yield (91.15%), and the encapsulation yield of total polyphenol content (61.44%), total flavonoid content (37.42%), and vitamin C (27.19%), with a predicted monolayer moisture content below 4.01%, according to the BET equation. The powder exhibited good dissolution characteristics in the acidic hydrophilic food simulation environment and showed greater stability when stored at 10 °C for 30 days, compared to storage at 35 °C and 45 °C. Full article
Show Figures

Figure 1

16 pages, 5047 KiB  
Article
Surface Plasmon Waveguide Based on Nested Dielectric Parallel Nanowire Pairs Coated with Graphene
by Lixia Yu, Ji Liu and Wenrui Xue
Photonics 2024, 11(5), 441; https://doi.org/10.3390/photonics11050441 (registering DOI) - 9 May 2024
Abstract
A kind of surface plasmon waveguide composed of two nested cylindrical dielectric parallel nanowire pairs coated with graphene was designed and studied. The dependence of the mode characteristics and the normalized gradient force of the lowest two modes supported by the waveguide on [...] Read more.
A kind of surface plasmon waveguide composed of two nested cylindrical dielectric parallel nanowire pairs coated with graphene was designed and studied. The dependence of the mode characteristics and the normalized gradient force of the lowest two modes supported by the waveguide on the parameters involved were analyzed by using the multipole method. To ensure rigor, the finite element method was employed to verify the accuracy of the multipole method, thus confirming its results. The results show that the multipole method is a powerful tool for handling this type of waveguide. The real part of the effective refractive index, the propagation length, the figure of merit, and the normalized gradient force can be significantly affected by the operating wavelength, the Fermi energy of graphene, the waveguide geometric parameters, and the refractive index of the inner dielectric nanowire. Due to the employment of nested dielectric nanowire pairs coated with graphene, this waveguide structure exhibits significant gradient force that surpasses 100 nN·μm−1·mW−1. The observed phenomena can be attributed to the interaction of the field with graphene. This waveguide holds promising potential for applications in micro/nano integration, optical tweezers, and sensing technologies. Full article
(This article belongs to the Special Issue Design and Applications of Novel Nanophotonics Devices)
Show Figures

Figure 1

16 pages, 8113 KiB  
Article
Application of CO2-Laser Micro-Perforation Technology to Freeze-Drying Whole Strawberry (Fragaria ananassa Duch.): Effect on Primary Drying Time and Fruit Quality
by Marlene Pinto, Cynthia Kusch, Karyn Belmonte, Silvana Valdivia, Pedro Valencia, Cristian Ramírez and Sergio Almonacid
Foods 2024, 13(10), 1465; https://doi.org/10.3390/foods13101465 (registering DOI) - 9 May 2024
Abstract
Freeze-drying (FD) processing preserves foods by combining the most effective traditional technologies. FD conserves the structure, shape, freshness, nutritional/bioactive value, color, and aroma at levels similar to or better than those of refrigerated and frozen foods while delivering the shelf-stable convenience of canned/hot-air-dehydrated [...] Read more.
Freeze-drying (FD) processing preserves foods by combining the most effective traditional technologies. FD conserves the structure, shape, freshness, nutritional/bioactive value, color, and aroma at levels similar to or better than those of refrigerated and frozen foods while delivering the shelf-stable convenience of canned/hot-air-dehydrated foods. The mass transfer rate is the essential factor that can slow down the FD process, resulting in an excessive primary drying time and high energy consumption. The objective of this study was to reduce the FD processing time using CO2 laser technology to improve product competitiveness in the preservation of whole strawberries. The research process consisted of the selection and characterization of fresh strawberries, followed by preparation, pre-treatment, freeze-drying, a primary drying time assessment, and a quality comparison. Experiments were carried out using strawberries without micro-perforation and with five and eight micro-perforations. Quality parameters were determined for fresh, frozen/thawed, and freeze-dried/rehydrated strawberries. It was found that the primary drying time can be significantly reduced by 20% (95% CI) from 26.7 h for non-perforated fruits to 22.3 h when five micro-perforations are made on each strawberry. The quality parameters used to evaluate the strawberries did not show significant differences when comparing frozen/thawed fruits with freeze-dried/rehydrated fruits. The experiments conducted in this study showed that freeze-drying may efficiently compete with freezing technology when processing whole strawberries. Full article
(This article belongs to the Section Food Engineering and Technology)
Show Figures

Figure 1

Open Access Journals

Browse by Indexing Browse by Subject Selected Journals
Back to TopTop