Beat-to-beat (B2B) variability in biomedical signals has been shown to have high diagnostic power in the treatment of various cardiovascular and autonomic disorders. In recent years, new techniques and devices have been developed to enable non-invasive blood pressure (BP) measurements. In this work, we aim to establish the concept of two-dimensional signal warping, an approved method from ECG signal processing, for non-invasive continuous BP signals. To this end, we introduce a novel BP-specific beat annotation algorithm and a B2B-BP fluctuation (B2B-BPF) metric novel for BP measurements that considers the entire BP waveform. In addition to careful validation with synthetic data, we applied the generated analysis pipeline to non-invasive continuous BP signals of 44 healthy pregnant women (30.9 ± 5.7 years) between the 21st and 30th week of gestation (WOG). In line with established variability metrics, a significant increase (p < 0.05) in B2B-BPF can be observed with advancing WOGs. Our processing pipeline enables robust extraction of B2B-BPF, demonstrates the influence of various factors such as increasing WOG or exercise on blood pressure during pregnancy, and indicates the potential of novel non-invasive biosignal sensing techniques in diagnostics. The results represent B2B-BP changes in healthy pregnant women and allow for future comparison with those signals acquired from women with hypertensive disorders. Full article

For a micro-indentation hardness test with non-destructivity, the Nix–Gao model is widely used to describe tested hardness or microhardness variation with an indentation depth induced by indentation size effect, in which tested hardness approaches the macrohardness when the indentation depth is large enough. Based on an analysis of hardness measurements on 10 body-centered cubic steels with diverse microstructure, this paper proposes an analytical relation between microhardness to macrohardness ratio and the indentation depth by explicitly linking characteristic indentation depth (a data-fitting parameter) to grain size and ferrite volume fraction using two different methods. In addition, the normal distribution theory is incorporated to consider the inevitable scatter of identical measurements resulting from material heterogeneity and machining/testing errors. Results show that the proposed model, with 96% reliability, can effectively predict microhardness variation with the indentation depth and its scatter. Full article

This study aimed to assess the potential contributions of the Myers–Briggs Type Indicator (MBTI) to the sustainable growth of communities by conducting a comprehensive analysis of social perceptions of the MBTI in South Korea through big data analysis. The investigation encompasses three primary stages: data collection, preprocessing, and analysis, involving text mining, network analysis, CONCOR analysis, and sentiment analysis. A total of 31,308 text data pieces (13.73 MB) from various sources, including news, blogs, and other sections of Naver and Google, over the past three years, were collected and analyzed using the keyword “MBTI.” Tools, such as Textom SV, UCINET, and NetDraw, were employed for data collection and analysis. The study’s key findings include the identification, through term frequency (TF) and TF-inverse document frequency analyses, of top-ranking terms, such as 16Types, 4Indicators, Test, Myself, OthersMBTI, Situation, and Contents. The CONCOR analysis further revealed six clusters, encompassing themes like interest in MBTI personality tests, application of 16 types in daily life, MZ’s MBTI consumption patterns, trending of MBTI characters, extension to K-Test, and professional use of MBTI. Moreover, sentiment analysis indicated that 68.5% of individuals in South Korea expressed a positive sentiment towards MBTI, while 31.5% conveyed a negative sentiment. The specific emotions identified included liking (Good Feeling), disgust, and interest, in order of prominence. In light of these findings, this study delineates a spectrum of perceptions regarding MBTI in South Korea, encompassing both positive interests and negative concerns. To ensure the responsible use of MBTI, it is imperative to implement reliable scientific testing and education, mitigate the potential harm of stereotyping, and reshape social perceptions surrounding MBTI usage. Only through these measures can MBTI genuinely contribute to the sustainable growth of communities without being confined to limiting stereotypes. Full article

This study examined the impact of tea polyphenols (TPs) on the intestinal flora of loaches (Paramisgurnus dabryanus) under chronic ammonia nitrogen stress using high-throughput sequencing. Two groups of 600 loaches were studied over one month, and they were separated into a control group and tea polyphenol group. Alpha and beta diversity analyses showed diverse bacterial communities, with significant differences in the abundance and uniformity observed initially but not between sampling time points. Cluster analyses revealed distinct differences in microbial communities between groups. A predictive function analysis indicated enrichment in pathways related to amino acid and nucleotide biosynthesis. These findings offer initial insights into how tea polyphenols may affect intestinal microbial communities in loaches under ammonia nitrogen stress. Full article

In this study, we investigated the feasibility of using electroencephalogram (EEG) signals to differentiate between four distinct subject-driven cognitive states: resting state, narrative memory, music, and subtraction tasks. EEG data were collected from seven healthy male participants while performing these cognitive tasks, and the raw EEG signals were transformed into time–frequency maps using continuous wavelet transform. Based on these time–frequency maps, we developed a convolutional neural network model (TF-CNN-CFA) with a channel and frequency attention mechanism to automatically distinguish between these cognitive states. The experimental results demonstrated that the model achieved an average classification accuracy of 76.14% in identifying these four cognitive states, significantly outperforming traditional EEG signal processing methods and other classical image classification algorithms. Furthermore, we investigated the impact of varying lengths of EEG signals on classification performance and found that TF-CNN-CFA demonstrates consistent performance across different window lengths, indicating its strong generalization capability. This study validates the ability of EEG to differentiate higher cognitive states, which could potentially offer a novel BCI paradigm. Full article

This study aimed to compare the nanoleakage of retrograde fillings with premixed calcium silicate-based putty and mineral trioxide aggregate (MTA), using two different techniques (traditional and Lid). Sixty-four extracted human teeth were decoronated, then root canals and ends were instrumented for retrograde filling and divided into four groups according to the retrograde filling technique: the traditional and the Lid technique. Each group (n = 15) was filled with Ceraseal + Well-Root putty, Well-Root putty, Ceraseal + ProRoot MTA, and ProRoot MTA. The nanoleakage was evaluated using the Nanoflow device (IB Systems) on days 1, 3, 7, 15 and 30. Data were collected twice per second at the nanoscale (nL/s) and calculated after archiving the stabilization of fluid flow. The Kruskal–Wallis and Mann–Whitney U-tests were used for statistical analysis. All groups showed enhanced sealing ability over time. Regardless of filling materials, the Well-Root putty, Ceraseal+Well-Root putty, and Ceraseal+ProRoot MTA groups indicated less nanoleakage than the ProRoot MTA group in the first week of evaluation (p < 0.05). Although all groups did not show significant differences after 2 weeks, the Ceraseal+ProRoot MTA group leaked less than ProRoot MTA on Days 3 and 7 (p < 0.05). The scanning electron microscopic examined good adaptation to the cavity wall, which was similar to nanoleakage results. Premixed calcium silicate-based putty retrograde filling material alone and using the “lid technique” were shown to be faster and less prone to nanoleakage when compared to MTA. Full article

Modularity and resilience are fundamental properties of brain network organization and function. The interplay of these network characteristics is integral to understanding brain vulnerability, network efficiency, and neurocognitive disorders. One potential methodology to explore brain network modularity and resilience is through percolation theory, a sub-branch of graph theory that simulates lesions across brain networks. In this work, percolation theory is applied to connectivity matrices derived from functional MRI from human, mice, and null networks. Nodes, or regions, with the highest betweenness centrality, a graph theory quantifier that examines shortest paths, were sequentially removed from the network. This attack methodology led to a rapid fracturing of the network, resulting in two terminal modules connected by one transfer module. Additionally, preceding the rapid network fracturing, the average betweenness centrality of the network peaked in value, indicating a critical point in brain network functionality. Thus, this work introduces a methodological perspective to identify hubs within the brain based on critical points that can be used as an architectural framework for a neural network. By applying percolation theory to functional brain networks through a network phase-transition lens, network sub-modules are identified using local spikes in betweenness centrality as an indicator of brain criticality. This modularity phase transition provides supporting evidence of the brain functioning at a near-critical point while showcasing a formalism to understand the computational efficiency of the brain as a neural network. Full article

To investigate the load-carrying performance of the nodes between tubular piles and bearing platforms, low circumferential reciprocating load foot-scale tests were performed on two truncated PHC B 600 130 tubular piles. The development law of node destruction was explored. The test results revealed that under the action of tensile–bending–shear loading, the bearing concrete in the node area buckled and was damaged, and an articulation point was formed. When the embedment depth increased from 200 mm to 300 mm, the ultimate bearing capacities of the positive and negative nodes increased by 57.60% and 54.60%, respectively. Numerical simulation was used to analyze the bearing capacities of nodes with different types and embedment depths. Formulas for the bearing capacity of the nodes were proposed. Furthermore, two preferred node types were proposed as follows: pipe pile core-filled longitudinal reinforcement anchored to the bearing node and pipe pile body longitudinal reinforcement anchored to the bearing node + pipe pile core-filled longitudinal reinforcement anchored to the bearing node, with preferred embedment depths of 350 mm and 200 mm, respectively. Full article

This review explores the critical role of advanced metabolomic methodologies in interpreting the complex relationship between the bioactive compounds in olive oil and their health benefits. Olive oil, the cornerstone of the Mediterranean diet, is renowned for its numerous health benefits, including anti-inflammatory, antioxidant, and cardioprotective properties. This review begins with an overview of the importance of olive oil for nutrition and health, followed by a detailed discussion of the key metabolites that contribute to its therapeutic potential. It further explores the evolution of analytical techniques in metabolomics from traditional methods to cutting-edge technologies, such as mass spectrometry and nuclear magnetic resonance spectroscopy, which have enhanced our understanding of the complex composition of olive oil. This review highlights how these advanced analytical findings correlate with the known health properties of olive oil and presents case studies in which these methodologies have led to new insights. Finally, we address the challenges in standardizing these techniques and discuss future research directions, underscoring the significance of metabolomics in nutritional science and public health. This comprehensive analysis aims to provide a deeper understanding of the health benefits of olive oil, informed by the latest advancements in analytical methodologies. Full article

In this paper, a novel data transmission scheme, interference perceptual multi-modulation (IP-MM), is proposed for full-duplex (FD) systems. In order to unlink the conventional uplink (UL) data transmission using a single modulation and coding scheme (MCS) over the entire assigned UL bandwidth, IP-MM enables the transmission of UL data channels based on multiple MCS levels, where a different MCS level is applied to each subband of UL transmission. In IP-MM, a deep convolutional neural network is used for MCS-level prediction for each UL subband by estimating the potential residual self-interference (SI) according to the downlink (DL) resource allocation pattern. In addition, a subband-based UL transmission procedure is introduced from a specification point of view to enable IP-MM-based UL transmission. The benefits of IP-MM are verified using simulations, and it is observed that IP-MM achieves approximately 20% throughput gain compared to the conventional UL transmission scheme. Full article

Currently, coastal sandy soils face issues such as insufficient foundation strength, which has become one of the crucial factors constraining urban development. Geotechnical engineering, as a traditional discipline, breaks down disciplinary barriers, promotes interdisciplinary integration, and realizes the green ecological and low-carbon development of geotechnical engineering, which is highly important. Based on the “dual carbon” concept advocating a green and environmentally friendly lifestyle, Bacillus spores were utilized to induce calcium carbonate precipitation technology (MICP) to solidify coastal sandy soils, leveraging the rough-surface and low-permeability characteristics of silty soil. The mechanical-strength variations in the samples were explored through experiments, such as calcium carbonate generation rate tests, non-consolidated undrained triaxial shear tests, and scanning electron microscopy (SEM) experiments, to investigate the MICP solidification mechanism. The results indicate that by incorporating silty soil into sandy soil for MICP solidification, the calcium carbonate generation rates of the samples were significantly increased. With the increase in the silty-soil content, the enhancement range was 0.58–3.62%, with the maximum calcium carbonate generation rate occurring at a 5% content level. As the silty-soil content gradually increased from 1% to 5%, the peak deviator stress increased by 4.2–43.2%, enhancing the sample shear strength. Furthermore, the relationship between the internal-friction angle, cohesion, and shear strength further validates the enhancement of the shear strength. Silty soil plays roles in adsorption and physical filling during the MICP solidification process, reducing the inter-particle pores in sandy soil, increasing the compactness, providing adsorption sites, and enhancing the calcium carbonate generation rate, thereby improving the shear strength. The research findings can provide guidance for reinforcing poor coastal sandy-soil foundations in various regions. Full article

This scientific study focuses on tuberculosis (TB) within prison settings, where persons deprived of liberty (PDL) face significantly higher rates of the disease compared to the general population. The research employs the low-cost amplicon sequencing of Mycobacterium tuberculosis strains, aiming first to identify specific lineages and also to detect mutations associated with drug resistance. The method involves multiplex amplification, DNA extraction, and sequencing, providing valuable insights into TB dynamics and resistance-mutation profiles within the prison system at an affordable cost. The study identifies a characteristic lineage (X) circulating among PDLs in the penitentiary system in Uruguay, absent in the general population, and notes its prevalence at prison entry. No high-confidence mutations associated with drug resistance were found. The findings underscore the importance of molecular epidemiology in TB control, emphasizing the potential for intra-prison transmissions and the need for broader studies to understand strain dynamics. Full article

Is additive manufacturing (AM) a sustainable process? Can the process be optimised to produce sustainable AM parts and production techniques? Additive manufacturing offers the production of parts made of different types of materials in addition to the complex geometry that is difficult or impossible to produce by using the traditional subtractive methods. This study is focused on the optimisation of laser powder bed fusion (L-PBF), one of the most common technologies used in additive manufacturing and 3D printing. This research was carried out by modulating the build layer thickness of the deposited metal powder and the input volumetric energy density. The aim of the proposed strategy is to save the build time by maximizing the applied layer thickness of nitinol powder while retrieving the different AM part properties. The saving in the process time has a direct effect on the total cost of the produced part as a result of several components like electric energy, inert gas consumption, and labour. Nickel-rich nitinol (52.39 Ni at.%) was selected for investigation in this study due to its extremely high superplastic and shape memory properties in addition to the wide application in various industries like aerospace, biomedical, and automotive. The results obtained show that significant energy and material consumption can be found by producing near full dens AM parts with limited or no alteration in chemical and mechanical properties. Full article

This article analyzes the implementation of the National Financial Inclusion Strategy (NFIS) and its alignment with Sustainable Development Goal (SDG) I: Eradicate poverty. Despite the progress achieved, structural gaps persist and substantially limit the NFIS’s contribution to poverty reduction, especially among rural, indigenous, extreme poverty, and other vulnerable groups. The article employs a mixed methods approach combining qualitative and quantitative techniques. On the qualitative side, a hermeneutic documentary analysis of the NFIS and related regulations was carried out, with a critical textual interpretation supported by specialized software. Quantitatively, descriptive statistical techniques were applied to analyze official financial inclusion indicators—methodological integration was achieved through analytical triangulation under a concurrent mixed methods approach. The progress of initiatives under the NFIS was evaluated, identifying limitations such as the digital divide in rural areas, limited financing for Micro and Small Enterprises, gaps in financial education, and growing exposure to digital fraud. Although the NFIS promotes greater access to financial services, it does not explicitly focus on the poorest and most excluded populations. Therefore, it is recommended that the objectives and indicators of the NFIS be reformulated to focus on universal access and effective use of financial services by the population in extreme poverty and chronic exclusion. In addition, a strategic articulation with social protection policies is necessary, as well as promoting culturally relevant microfinance and inclusive finance models, strengthening consumer protection, and consolidating public–private alliances in high-poverty areas. Finally, strong monitoring and accountability are also key. Full article

Research has established that the incorporation of 3D-printed lattice structures in cement substrates enhances the mechanical properties of cementitious materials. However, given that 3D-printing materials, notably polymers, exhibit varying degrees of mechanical performance under high-temperature conditions, their efficacy is compromised. Notably, at temperatures reaching 150 °C, these materials soften and lose their load-bearing capacity, necessitating further investigation into their compressive mechanical behavior in such environments. This study evaluates the compressibility of cement materials reinforced with lattice structures made from polyamide 6 (PA6) across different structural configurations and ambient temperatures, employing ABAQUS for simulation. Six distinct 3D-printed lattice designs with equivalent volume but varying configurations were tested under ambient temperatures of 20 °C, 50 °C, and 100 °C to assess their impact on compressive properties. The findings indicate that heightened ambient temperatures significantly diminish the reinforcing effect of 3D-printed materials on the properties of cement-based composites. Full article

Porphyra sensu lato has economic importance for food and pharmaceutical industries due to its significant physiological activities resulting from its bioactive compounds (BACs). This study aimed to determine the optimal nitrate dosage required in short-term cultivation to achieve substantial BAC production. A nitrate experiment using varied concentrations (0 to 6.5 mM) revealed optimal nitrate uptake at 0.5 mM in the first two days and at 3 and 5 mM in the last five days. Polyphenols and carbohydrates showed no differences between treatments, while soluble proteins peaked at 1.5 and 3 mM. Total mycosporine-like amino acids (MAAs) were highest in algae incubated at 5 and 6.5 mM, and the highest antioxidant activity was observed in the 5 mM, potentially related to the MAAs amount. Total carbon and sulfur did not differ between treatments, while nitrogen decreased at higher nitrate. This discovery highlights the nuanced role of nitrate in algal physiology, suggesting that biological and chemical responses to nitrate supplementation can optimize an organism’s health and its commercially significant bioactive potential. Furthermore, given its ability to absorb high doses of nitrate, this alga can be cultivated in eutrophic zones or even in out-/indoor tanks, becoming an excellent option for integrated multi-trophic aquaculture (IMTA) and bioremediation. Full article

Encoded by the CDX2 homeobox gene, the CDX2 protein assumes the role of a pivotal transcription factor localized within the nucleus of intestinal epithelial cells, orchestrating the delicate equilibrium of intestinal physiology while intricately guiding the precise development and differentiation of epithelial tissue. Emerging research has unveiled that positive immunohistochemical expression of this protein shows that the CDX2 gene exerts a potent suppressive impact on tumor advancement in colorectal cancer, impeding the proliferation and distant dissemination of tumor cells, while the inhibition or suppression of CDX2 frequently correlates with aggressive behavior in colorectal cancer. In this study, we conducted an immunohistochemical assessment of CDX2 expression on a cohort of 43 intraoperatively obtained tumor specimens from patients diagnosed with colon cancer at Colțea Clinical Hospital in Bucharest, between April 2019 and December 2023. Additionally, we shed light on the morphological diversity within colon tumors, uncovering varying differentiation grades within the same tumor, reflecting the variations in CDX2 expression as well as the genetic complexity underlying these tumors. Based on the findings, we developed an innovative immunohistochemical scoring system that addresses the heterogeneous nature of colon tumors. Comprehensive statistical analysis of CDX2 immunohistochemical expression unveiled significant correlations with known histopathological parameters such as tumor differentiation grades (p-value = 0.011) and tumor budding score (p-value = 0.002), providing intriguing insights into the complex involvement of the CDX2 gene in orchestrating tumor progression through modulation of differentiation processes, and highlighting its role in metastatic predisposition. The compelling correlation identified between CDX2 expression and conventional histopathological parameters emphasizes the prognostic significance of the CDX2 biomarker in colon cancer. Moreover, our novel immunohistochemical scoring system reveals a distinct subset of colon tumors exhibiting reserved prognostic outcomes, distinguished by their “mosaic” CDX2 expression pattern. Full article

This paper focuses on the mathematical and numerical modeling of the electric arc + laser beam welding (HLAW) process using an innovative model of the Yb:YAG laser heat source. Laser energy distribution is measured experimentally using a UFF100 analyzer. The results of experimental research, including the beam profile and energetic characteristics of an electric arc, are used in the model. The laser beam description is based on geostatistical kriging interpolation, whereas the electric arc is modeled using Goldak’s distribution. Hybrid heat source models are used in numerical algorithms to analyze physical phenomena occurring in the laser–arc hybrid welding process. Thermal phenomena with fluid flow in the fusion zone (FZ) are described by continuum conservation equations. The kinetics of phase transformations in the solid state are determined using Johnson–Mehl–Avrami (JMA) and Koistinen–Marburger (KM) equations. A continuous cooling transformation (CCT) diagram is determined using interpolation functions and experimental research. An experimental dilatometric analysis for the chosen cooling rates is performed to define the start and final temperatures as well as the start and final times of phase transformations. Computer simulations of butt-welding of S355 steel are executed to describe temperature and melted material velocity profiles. The predicted FZ and heat-affected zone (HAZ) are compared to cross-sections of hybrid welded joints, performed using different laser beam focusing. The obtained results confirm the significant influence of the power distribution of the heat source and the laser beam focusing point on the temperature distribution and the characteristic zones of the joint. Full article

Although adverse events of proton pump inhibitors (PPIs) have been reported, there are few studies on physicians’ perceptions. We aimed to investigate physicians’ awareness of PPI-related adverse events and changes in treatment patterns according to their practice. We conducted an online survey of physicians using a 15-item questionnaire. The survey queried respondents’ demographic information, PPI prescription patterns, perceptions, and concerns on the reported PPI-related adverse events. Concerns regarding the adverse events of PPI were assessed by dividing them into possibilities and medical causality. Of the 450 respondents, 430 were specialists, and 232 were gastroenterologists. A total of 87.8% of the respondents were generally or well aware of the adverse effects of PPI, 29.1% considered side effects when prescribing PPI, and 14.6% explained them to patients. Specialists were more aware of the side effects of PPI than general practitioners (p = 0.005), and gastroenterologists were more aware of the side effects of PPI than non-gastroenterologists (p < 0.001). However, gastroenterologists explained less to patients (p = 0.001) and preferred to reduce the dose of PPI rather than discontinue it. The adverse events that were recognized as having the highest probability of occurrence and strongest association with PPI use were bone diseases, Clostridium difficile infection, gastrointestinal infection, pneumonia, and interactions with anti-thrombotic drugs. Physicians’ awareness of PPI-related adverse events and treatment patterns differed significantly according to their positions and practice. Although a number of adverse events of PPIs were reported, physicians seem to accept their significance differently according to their specialty and practice patterns. Full article

This work represents a preliminary study of atmospheric plasma-sprayed (APS) Yttria-Stabilized Zirconia (YSZ)-based thermal barrier coatings (TBCs) deposited on forged and additive manufactured (AM) HAYNES^®282^® (H282) superalloy substrates. The effect of different feedstock morphologies and spray gun designs with radial and axial injection on APS-deposited YSZ layer characteristics such as microstructure, porosity content, roughness, etc., has been investigated. The performance of TBCs in terms of thermal cycling fatigue (TCF) lifetime and erosion behaviour were also comprehensively investigated. In view of the high surface roughness of as-built AM surfaces compared to forged substrates, two different types of NiCoCrAlY bond coats were examined: one involved high-velocity air fuel (HVAF) spraying of a finer powder, and the other involved APS deposition of a coarser feedstock. Despite the process and feedstock differences, the above two routes yielded comparable bond coat surface roughness on both types of substrates. Variation in porosity level in the APS topcoat was observed when deposited using different YSZ feedstock powders employing axial or radial injection. However, the resultant TBCs on AM-derived substrates were observed to possess similar microstructures and functional properties as TBCs deposited on reference (forged) substrates for any given YSZ deposition process and feedstock. Full article

Background: Black and white women describe their chronic vulvar pain (CVVP) symptoms differently, indicating a patient–provider communication deficit. This may contribute to the diagnostic delay commonly reported by patients with CVVP and/or pelvic pain. Methods: A pilot study demonstrated CVVP terminology differences between women of color and white women. The present study (N = 488) includes a sample of predominantly cisgender women who identified their race/ethnicity as Black, Hispanic/Latinx, Native American/American Indian, and/or Asian. Participants reported how they describe their CVVP, their healthcare experiences, and characteristics of their diagnostic journey. Results: Descriptions of CVVP were not uniform. Instead, there was great variability in how women described their pain across racial/ethnic identities and pain contexts (e.g., sexual activity, menstrual product use, and pelvic exam). Some pain experiences and descriptors were associated with healthcare outcomes related to diagnostic delay. Conclusions: This study sheds light on the pain communication experiences of women of color with CVVP, an understudied population within the broader CVVP literature. By resisting white and non-white comparative methodologies, this study demonstrates the applicability of intersectionality principles to the study of CVVP and contributes to the existing literature regarding pain communication, race, and ethnicity. Full article

To explore the compensation effect of aeration on tomato vegetative and reproductive growth in arid and semi-arid areas, a two-year field experiment was conducted with four micro-nano aeration ratios (0%, 5%, 10%, and 15%) and three nitrogen topdressing levels (80, 60, and 40 kg·ha⁻¹) during the tomato growth period in Ningxia, China. The results showed that increasing the aeration ratio in the range of 0–15% was conducive to the enhancement of tomato root vigor (the ability of triphenyltetrazolium chloride to be reduced, 3–104%) and the leaf net photosynthetic rate (14–63%), favorable to the facilitation of plant dry matter accumulation (3–59%) and plant nitrogen accumulation (2–70%), and beneficial to the improvement of tomato yield (12–44%) and fruit quality. Interestingly, since the aeration ratio exceeded 10%, the increase in the aeration ratio showed no significant effects on the single-fruit weight, tomato yield, and fruit quality. Moreover, with aerated underground drip irrigation, properly reducing the traditional nitrogen topdressing level (80 kg·ha⁻¹) by 25% was favorable for enhancing tomato root vigor (5–31%), increasing tomato yield (0.5–9%), and improving fruit soluble solid accumulation (2–5%) and soluble sugar formation (4–9%). Importantly, increasing the aeration ratio by 5% could compensate for the adverse effects of reducing the nitrogen topdressing level by 25% by improving the leaf photosynthetic rate, promoting plant dry matter accumulation, increasing tomato yield, and enhancing the soluble solid and soluble sugar accumulation in tomato fruits. Synthetically considering the decrease in the nitrogen topdressing amount, leading to plant growth promotion, a tomato yield increase, and fruit quality improvement, a favorable nitrogen topdressing level of 60 kg·ha⁻¹ and the corresponding proper aeration ratio of 10% were suggested for tomato underground drip irrigation in the Yinbei Irrigation District of Ningxia. Full article