Pulmonary oncological pathologies are an important public health problem and the association with other pulmonary lesions may pose difficulties in diagnosis and staging or require different treatment options. To address this complexity, we conducted a retrospective observational study at the Marius Nasta Institute of Pneumophthisiology, Bucharest, Romania. Our study focused on patients admitted in 2019 with non-small-cell lung carcinoma and associated pulmonary lesions identified through surgical resection specimens. Among the 314 included patients, multiple pulmonary nodules were observed on macroscopic examination, with 12% (N = 37) exhibiting nonmalignant etiologies upon microscopic examination. These findings underscore the challenge of preoperative staging. Patients with coexisting nonmalignant lesions were similar in age, smoking habits, and professional or environmental exposure by comparison with those who presented only malignant lesions. The presentation of coexisting malignant and nonmalignant lesions may pose difficulties in diagnosing and staging pulmonary cancer. Full article

A viable green energy source for heavy industries and transportation is hydrogen. The internal combustion engine (ICE), when powered by hydrogen, offers an economical and adaptable way to quickly decarbonize the transportation industry. In general, two techniques are used to inject hydrogen into the ICE combustion chamber: port injection and direct injection. The present work examined direct injection technology, highlighting the need to understand and manage hydrogen mixing within an ICE’s combustion chamber. Before combusting hydrogen, it is critical to study its propagation and mixture behavior just immediately before burning. For this purpose, the DI-CHG.2 direct injector model by BorgWarner was used. This injector operated at 35 barG and 20 barG as maximum and minimum upstream pressures, respectively; a 5.8 g/s flow rate; and a maximum tip nozzle temperature of 250 °C. Experiments were performed using a high-pressure and high-temperature visualization vessel available at our facility. The combustion mixture prior to burning (spray) was visually controlled by the single-pass high-speed Schlieren technique. Images were used to study the spray penetration (S) and spray volume (V). Several parameters were considered to perform the experiments, such as the injection pressure (P_inj), chamber temperature (T_ch), and the injection energizing time (T_inj). With pressure ratio and injection time being the parameters commonly used in jet characterization, the addition of temperature formed a more comprehensive group of parameters that should generally aid in the characterization of this type of gas jets as well as the understanding of the combined effect of the rate of injection on the overall outcome. It was observed that the increase in injection pressure (P_inj) increased the spray penetration depth and its calculated volume, as well as the amount of mass injected inside the chamber according to the ROI results; furthermore, it was also observed that with a pressure difference of 20 bar (the minimum required for the proper functioning of the injector used), cyclic variability increased. The variation in temperature inside the chamber had less of an impact on the spray shape and its penetration; instead, it determined the velocity at which the spray reached its maximum length. In addition, the injection energizing time had no effect on the spray penetration. Full article

Background: The inflammasome is a cytosolic multiprotein complex associated with multiple autoimmune diseases. Phytochemical compounds in soy (Glycine max) foods, such as isoflavones, have been reported for their anti-inflammatory properties. Aim: the anti-inflammatory activity of DZ (daidzein) and EQ (equol) were investigated in an ex vivo model of LPS-stimulated murine peritoneal macrophages and by molecular docking correlation. Methods: Cells were pre-treated with DZ (25, 50, and 100 µM) or EQ (5, 10, and 25 µM), followed by LPS stimulation. The levels of PGE₂, NO, TNF-α, IL-6, and IL-1β were analyzed by ELISA, whereas the expressions of COX-2, iNOS, NLRP3, ASC, caspase 1, and IL-18 were measured by Western blotting. Also, the potential for transcriptional modulation by targeting NF-κB, COX-2, iNOS, NLRP3, ASC, and caspase 1 was investigated by molecular docking. Results: The anti-inflammatory responses observed may be due to the modulation of NF-κB due to the binding of DZ or EQ, which is translated into decreased TNF-α, COX-2, iNOS, NLRP3, and ASC levels. Conclusion: This study establishes that DZ and EQ inhibit LPS-induced inflammatory responses in peritoneal murine macrophages via down-regulation of NO and PGE₂ generation, as well as the inhibition of the canonical inflammasome pathway, regulating NLRP3, and consequently decreasing IL-1β and IL-18 activation. Full article

Electricity consumption in homes is on the rise due to the increasing prevalence of home appliances and longer hours spent indoors. Home energy management systems (HEMSs) are emerging as a solution to reduce electricity consumption and efficiently manage power usage at home. In the past, numerous studies have been conducted on the management of electricity production and consumption through solar power. However, there are limited human-centered studies focusing on the user’s lifestyle. In this study, we propose an Intelligent Home Energy Management System (i-HEMS) and evaluate its energy-saving effectiveness through a demonstration in a standard house in Korea. The system utilizes an IoT environment, PID sensing, and behavioral pattern algorithms. We developed algorithms based on power usage monitoring data of home appliances and human body detection. These algorithms are used as the primary scheduling algorithm and a secondary algorithm for backup purposes. We explored the deep connection between power usage, environmental sensor data, and input schedule data based on Long Short-Term Memory network (LSTM) and developed an occupancy prediction algorithm. We analyzed the use of common home appliances (TV, computer, water purifier, microwave, washing machine, etc.) in a standard house and the power consumption reduction by the i-HEMS system. Through a total of six days of empirical experiments, before implementing i-HEMS, home appliances consumed 13,062 Wh. With i-HEMS, the total consumption was reduced to 10,434 Wh (a 20% reduction), with 9060 Wh attributed to home appliances and 1374 Wh to i-HEMS operation. Full article

Electrocardiogram (ECG) abnormalities are the most common cardiac complications after acute ischemic stroke (AIS) and predict poor outcomes. The arterial baroreflex is an essential determinant of cardiovascular autonomic regulation, with receptors mainly residing in carotid sinuses and aortic arch. The atherosclerosis of these baroreceptor-resident arteries (BRA) is very common in AIS patients and might impair baroreflex function. However, the associations between the atherosclerosis of BRA and ECG abnormalities after AIS are still unknown. In total, 228 AIS patients within 7 days after onset without a pre-existing heart disease were prospectively recruited. With computed tomography angiography, atherosclerosis conditions in 10 segments of the carotid sinuses and aortic arch were scored and summed as the Total Atherosclerosis Burden of BRA (TAB-BRA), and asymptomatic coronary artery stenosis (ACAS) ≥50% was simultaneously assessed. We performed 12-lead ECG to dynamically detect abnormal repolarization, and 24 h Holter ECG to monitor arrhythmias and heart rate variability (HRV) parameters, which are reliable indicators to assess cardiac autonomic function. We found that TAB-BRA was positively associated with abnormal repolarization (OR 1.09; CI% 1.03–1.16; p = 0.003) and serious cardiac arrhythmias (OR 1.08; CI% 1.01–1.15; p = 0.021). In addition, TAB-BRA was an important predictor of abnormal repolarization, persisting over 3 days (OR 1.17; CI% 1.05–1.30; p = 0.003). However, ACAS ≥ 50% did not relate to these ECG abnormalities. TAB-BRA was negatively correlated with parasympathetic-related HRV parameters. Our results indicated that AIS patients with a high TAB-BRA are more likely to have ECG abnormalities and delayed normalization, which may relate to the decreased cardiac parasympathetic activity, but not the accompanied ACAS ≥ 50%. Full article

Single-crystal diamond tools occupy an important position in the field of optical processing as the basis and key to advanced optical manufacturing technology, such as grating manufacturing and optical mirror-turning processing. Single-crystal diamond tools have become the cornerstone of the development of related industries. This paper takes a single-crystal diamond arc tool as the research object. Sound signal analysis technology and vibration signal analysis technology are comprehensively applied to the online orientation identification of a single-crystal diamond tool in the indexing grinding process. The online orientation method of the tool is explored, the sound signal and the vibration signal are taken as the characteristic signals, and a wavelet algorithm (WT) is used to reduce the noise of the vibration signal and sound signal. The kurtosis of the sound signal and the kurtosis and skewness of the vibration signal in the high-order statistics strongly related to the grinding direction of a single-crystal diamond are used as the characteristic parameters, and the online direction recognition model of the tool is established using the Hidden Markov Method (HMM). The above characteristic parameters are used as model input for multi-information fusion. The mapping relationship between the characteristic parameters of the characteristic signal and the crystal orientation of the single-crystal diamond crystal face is obtained, and then the online orientation method of the single-crystal diamond arc tool in the process of indexing grinding is formed. The effectiveness of the method is verified by experiments, and effective orientation information is provided for research on the positioning control strategy of the tool grinding process to ensure the efficiency of grinding and improve the manufacturing level of the tool. Full article

Frequency-dependent predation is common in predator–prey interactions. Size is an important characteristic of seeds and is crucial in the regeneration stage of plant seeds. However, the frequency dependence of animal predation on seed size has not been reported. In this study, we conducted a field experiment and used different sizes of Liaodong oak (Quercus wutaishanica) seeds to test the frequency dependence of intraspecific seed size selection in rodents. We used the number ratio of large to small seeds as the frequency. The results show that the rate of small seeds being eaten in situ was significantly higher than that of large seeds (p < 0.05). The rates of different-sized seeds being eaten after removal decreased with increasing frequencies, and there was no significant difference between frequencies except for 1:9 and 9:1. The rates of large seeds being scatter-hoarded were significantly higher than those of small seeds at different frequencies (p < 0.05). The eating distances after removal of large seeds were significantly longer than those of small seeds at the same frequencies (p < 0.05). Furthermore, the scatter-hoarding distances of large seeds were significantly longer than those of small seeds at three frequencies (1:9, 3:7, and 9:1) (p < 0.05). That is, rodents consumed more small seeds in situ, dispersed and scatter-hoarded more large seeds, and dispersed large seeds over longer distances. Rodents exhibited a negative frequency dependence for small seeds and a positive frequency dependence for large seeds on being eaten in situ. Moreover, rodents exhibited a negative frequency dependence for large seeds and a positive frequency dependence for small seeds on being eaten after removal and scatter-hoarding. These results reveal the frequency dependence of rodent selection on seed size and provide new insights into animal-mediated seed dispersal and the regeneration of plant populations. Full article

Background/Objectives: We conducted a comprehensive investigation to explore the pathological expression of the CXCR4 receptor in lymphoproliferative disorders (LPDs) using [⁶⁸Ga]Ga-Pentixafor PET/CT or PET/MRI technology. The PICO question was as follows: What is the diagnostic role (outcome) of [⁶⁸Ga]Ga-Pentixafor PET (intervention) in patients with LPDs (problem/population)? Methods: The study was written based on the reporting items for systematic reviews and meta-analyses (PRISMA) 2020 guidelines, and it was registered on the prospective register of systematic reviews (PROSPERO) website (CRD42024506866). A comprehensive computer literature search of Scopus, MEDLINE, Scholar, and Embase databases was conducted, including articles indexed up to February 2024. To the methodological evaluation of the studies used the quality assessment of diagnosis accuracy studies-2 (QUADAS-2) tool. Results: Of the 8380 records discovered, 23 were suitable for systematic review. Fifteen studies (on 571 LPD patients) focused on diagnosis and staging, and eight trials (194 LPD patients) assessed treatment response. Conclusions: The main conclusions that can be inferred from the published studies are as follows: (a) [⁶⁸Ga]Ga-Pentixafor PET may have excellent diagnostic performance in the study of several LPDs; (b) [⁶⁸Ga]Ga-Pentixafor PET may be superior to [¹⁸F]FDG or complementary in some LPDs variants and settings; (c) multiple myeloma seems to have a high uptake of [⁶⁸Ga]Ga-Pentixafor. Overall, this technique is probably suitable for imaging, staging, and follow-up on patients with LPD. Due to limited data, further studies are warranted to confirm the promising role of [⁶⁸Ga]Ga-Pantixafor in this context. Full article

Cultural industries constitute a crucial part of the sustainable economy. In accordance with the principles of socialist public ownership nations, the economic benefits of cultural industries should be ultimately transformed into more significant social benefits. Guided by the policies and requirements of the Chinese government concerning the social benefits of cultural industries, this paper innovatively integrates Data Envelopment Analysis (DEA) and Tobit models to empirically analyze the social benefits and their influencing factors within China’s cultural industries. The findings indicate that the social benefits of China’s cultural industries are currently in a state of diminishing returns to scale, with fiscal support and educational levels significantly enhancing the industry’s social benefits. This paper recommends that policymakers aiming to convert the economic benefits of cultural industries into social benefits more systematically and effectively should focus on enhancing the quality of industry outputs. Full article

Adherence to fire safety regulations for wood is one of the most important tasks in its use in structural and architectural applications. This article deals with determining the influence of heat flux on the ignition process of spruce (Picea abies L. Karst.) and beech wood (Fagus sylvatica L.). The heat flux was generated by an electric radiant panel. The analysed parameters included the ignition time of the spruce and beech wood samples, the influence of wood density, and sample moisture, and the course of sample combustion, both with and without flame, was observed. The heat flux was maintained at constant values, depending on the distance of the examined sample from the panel, along with the specific power of the radiation panel. The power of the radiation panel was set to constant values of 5 kW and 10 kW. The samples were placed at distances of 50, 70, 100, 150, and 200 mm from the heat source, and heat fluxes in the range of 13–92 kW·m⁻² were observed. At a power of 5 kW and a heat flux of 64 kW·m⁻², neither the sample of beech nor that of spruce wood, placed at the distance of 100 mm from the radiation panel, exhibited flaming combustion. The ignition time for the beech wood was approximately twice that of the spruce wood, likely due to the higher average wood density. It can be stated that wood density, as one of the main factors, significantly influences the ignition phase of burning. The statistical analysis examined variables including wood type, radiant panel output, distance, and heat flux in relation to ignition time. The analysis revealed a significant difference between ignition time and distance (p-value = 0.0000, H = 37.51583) as well as between ignition time and heat flux (p-value = 0.0000, H = 37.69726). Similarly, the time to ignition for all tested beech wood samples was longer than for spruce wood. Full article

Pile spacing is an important factor affecting the bearing capacity of concrete expansion pile (CEP) groups. In this study, a pile group was simulated and analyzed using ANSYS software R19.0. The influence of pile spacing on the bearing capacity of the pile group under a vertical load was determined using three sets of four-, six-, and nine-pile models with different pile spacings. The grid division of the pile soil model adopts a mapping method, using the contact types of rigid and flexible bodies and applying surface loads to the model piles step-by-step. After vertical pressure was applied to the model pile, in-depth analysis was conducted on the displacement cloud map, pile top displacement, and other data. The different stress conditions of corner, edge, and center piles in each model group were compared and analyzed, revealing the relationship between the stress mechanism and failure law of the soil around the pile and the pile spacing. It was found that the soil displacement range of edge piles is slightly larger than that of corner piles. This phenomenon gradually decreases with increasing pile spacing. When the pile spacing increases to four times the cantilever diameter, the difference in soil displacement at different pile positions is small, and the pile spacing has little effect on the compressive bearing capacity of the pile group. Thus, it is reasonable to control the pile spacing at three to four times the cantilever diameter. In the nine-pile model, when the load is loaded to the 20-step level, the displacement value of the central pile is −72.278 mm, while the displacement values of the edge pile and corner pile are −69.012 mm and −66.806 mm. It is shown that increasing the pile spacing can effectively reduce the pile group effect and improve the bearing capacity of the pile foundation. At present, CEP pile groups are gradually being applied in practical engineering, but research on the influence of pile spacing on the compressive bearing performance of CEP pile groups is still at a very early stage. This article reinforces the influence of pile spacing on the compressive bearing performance of CEP pile groups. It provides theoretical support for its application in practical engineering. Full article

Early diagnosis is essential for the successful management of Burkholderia pseudomallei infection, but it cannot be achieved by the current gold standard culture technique. Therefore, this study aimed to develop a lateral flow immunoassay (LFIA) targeting B. pseudomallei capsular polysaccharide. The development was performed by varying nitrocellulose membrane reaction pads and chase buffers. The prototype LFIA is composed of Unisart CN95 and chase buffer containing tris-base, casein, and Surfactant 10G. The assay showed no cross-reactivity with E. coli, S. aureus, P. aeruginosa, and P. acne. The limit of detections (LODs) of the prototype LFIA was 10⁷ and 10⁶ CFU/mL B. pseudomallei in hemoculture medium and artificial urine, respectively. These LODs suggest that this prototype can detect melioidosis from positive hemoculture bottles but not straight from urine. Additionally, these LODs are still inferior compared to Active Melioidosis Detect (AMD^TM). Overall, this prototype holds the potential to be used clinically with hemoculture bottles. However, further improvements should be considered, especially for use with urine samples. Full article

This article provides an overview of the use of ¹⁸F-FDG PET/CT in various clinical scenarios of head–neck squamous cell carcinoma, ranging from initial staging to treatment-response assessment, and post-therapy follow-up, with a focus on the current evidence, debated issues, and innovative applications. Methodological aspects and the most frequent pitfalls in head–neck imaging interpretation are described. In the initial work-up, ¹⁸F-FDG PET/CT is recommended in patients with metastatic cervical lymphadenectomy and occult primary tumor; moreover, it is a well-established imaging tool for detecting cervical nodal involvement, distant metastases, and synchronous primary tumors. Various ¹⁸F-FDG pre-treatment parameters show prognostic value in terms of disease progression and overall survival. In this scenario, an emerging role is played by radiomics and machine learning. For radiation-treatment planning, ¹⁸F-FDG PET/CT provides an accurate delineation of target volumes and treatment adaptation. Due to its high negative predictive value, ¹⁸F-FDG PET/CT, performed at least 12 weeks after the completion of chemoradiotherapy, can prevent unnecessary neck dissections. In addition to radiomics and machine learning, emerging applications include PET/MRI, which combines the high soft-tissue contrast of MRI with the metabolic information of PET, and the use of PET radiopharmaceuticals other than ¹⁸F-FDG, which can answer specific clinical needs. Full article

BRCA1 mutations predispose women to breast and ovarian cancer. The anticancer effect of zinc is typically linked to its antioxidant abilities and protecting cells against oxidative stress. Zinc regulates key processes in cancer development, including DNA repair, gene expression, and apoptosis. We took a blood sample from 989 female BRCA1 mutation carriers who were initially unaffected by cancer and followed them for a mean of 7.5 years thereafter. There were 172 incident cases of cancer, including 121 cases of breast cancer, 29 cases of ovarian cancers, and 22 cancers at other sites. A zinc level in the lowest tertile was associated with a modestly higher risk of ovarian cancer compared to women with zinc levels in the upper two tertiles (HR = 1.65; 95% CI 0.80 to 3.44; p = 0.18), but this was not significant. Among those women with zinc levels in the lowest tertile, the 10-year cumulative risk of ovarian cancer was 6.1%. Among those in the top two tertiles of zinc level, the ten-year cumulative risk of ovarian cancer was 4.7%. There was no significant association between zinc level and breast cancer risk. Our preliminary study does not support an association between serum zinc level and cancer risk in BRCA1 mutation carriers. Full article

To achieve sustainable development goals and meet the demand for clean and efficient energy utilization, it is imperative to advance the penetration of renewable energy in various sectors. Energy storage systems can mitigate the intermittent issues of renewable energy and enhance the efficiency and economic viability of existing energy facilities. Among various energy storage technologies, thermocline heat storage (THS) has garnered widespread attention from researchers due to its stability and economic advantages. Currently, there are only a few review articles focusing on THS, and there is a gap in the literature regarding the optimization design of THS systems. Therefore, this paper provides a comprehensive review of the recent research progress in THS, elucidating its principles, thermal storage materials, applications, and optimization designs. The novelty of this work lies in the detailed classification and analysis of various optimization designs for THS, including tank shape, aspect ratio, inlet/outlet configuration, thermal energy storage materials arrangement, operating strategies, and numerical model optimization approaches. The limitations of existing research are also identified, and future perspectives are proposed, aiming to provide recommendations for THS research and contribute to the development and promotion of THS technology. Full article

This multimethod study investigated an environmental recycling project in a Finnish kindergarten group, tailored for children aged 4 to 6, as part of early childhood environmental education for sustainable development. We aimed to identify the main drivers of sustainable lifestyles in the families of kindergarten children and evaluate the project’s effective practices. We utilized a qualitative approach using interviews with parents and feedback from teachers and employed the Following a Thread approach alongside inductive thematic analysis. The results highlight the crucial role of Finland’s socio-cultural context, including the emphasis on free play in natural settings and the encouragement of exploration under gentle guidance, in fostering sustainable behaviors among children. Additionally, the parents’ strong environmental sensitivity was manifested in their will to engage with their surrounding community to promote sustainability. The results underscore the importance of collaboration between parents and educators in promoting environmental awareness from an early age. The study advocates for policy changes to ensure that children and teachers have access to natural environments during day care, suggesting that integrating free play in nature with hands-on recycling activities can significantly contribute to sustainable education. Moreover, this topic should be further investigated in different living environments. Full article

To clarify the migration and accumulation of nitrogen (N), magnesium (Mg), calcium (Ca), and potassium (K) in soil profiles of plastic-greenhouse vegetable fields with cultivation years, soil samples from the 0–7 m soil profiles were collected from 10 pepper greenhouses with 10 and 20 years planting history, and parallel soil samples were taken from adjacent wheat-maize fields as controls. The results showed that: (1) Compared with wheat-maize fields, the total N amount in the 0–7 m soil layers from the greenhouses increased by 6.19 ± 1.16 and 9.11 ± 3.43 t ha⁻¹ at 10 and 20 years, respectively, accounting for about 30.4% and 17.5% of the N input. (2) The N amount that entered the environment outside the 0–7 m soil layers were 6.95 t ± 2.76 and 29.10 ± 10.14 t ha⁻¹ after 10 and 20 years of continuous planting, accounting for approximately 34.2% and 55.9% of the N input, respectively. (3) The concentration of water-soluble Ca and Mg in the 0–7 m soil layers increased significantly with cultivation years, and correlated positively with mineral N concentration. (4) Moreover, K mainly accumulates in the form of non-exchangeable K in the surface layers (0–50 cm). Our results demonstrated that huge amounts of N migrate to the deep soil with the extension of cultivation years in plastic-greenhouse pepper production systems, accompanied by significant leaching of Ca and Mg, while K mainly accumulates in the surface layers. Full article

Speed and agility have been described as crucial abilities for soccer players. The purpose of this study was to analyze, in detail, the variance in speed and agility tasks explained by lower-body power after controlling for age and body composition. The participants were 96 male soccer players aged 16.1 ± 1.6 years. Body composition (stature, body fat percentage—BF%, body mass, and fat-free mass—FFM), lower-body power (countermovement jump—CMJ, and squat jump—SJ), speed (5-, 10-, and 35 m sprints), and agility (t-test) were assessed. Among body composition parameters, BF% presented the highest number of significant relationships with speed and agility, with the strength of correlations ranging from small (5 m sprint, r = 0.25) to large (35 m sprint, r = 0.52). The strongest correlation coefficient emerged between FFM and the 35 m sprint (r = −0.65). Significant correlations were found between vertical jump performance and the 35 m sprint (CMJ: r = −0.68; SJ: r = −0.69), followed by the t-test (CMJ: r = −0.35; SJ: r = −0.47). The hierarchical multiple regression model could explain 22% to 67% of the variance observed in agility scores and speed. BF% remained the most statistically significant negative predictor of all regression models. The CMJ remained a statistically significant positive predictor of the 35 m sprint (β = −0.581, p ≤ 0.01) after controlling for age and body composition. Integrating programs targeting lower-body power might be important to enhance speed and agility performance in youth soccer. On the other hand, future research based on multidisciplinary approaches to investigate the effects of nutritional strategies in reducing or preventing gains in BF% is still needed, which remained a significant predictor of sprint and agility performance in the final models. Full article

Lattice structures have become an innovative solution for the improvement of part design, as they are able to substitute solid regions, maintain mechanical capabilities, and reduce material usage; however, dimensional quality control of these geometries is challenging. X-ray computed tomography (XCT) is the most suitable non-destructive metrological technique as it is capable of characterizing internal features and hidden elements. Uncertainty estimation of XCT is still in development, and studies typically use high-resolution calibrated devices such as focal variation microscopes (FVMs) as a reference, focusing on certain parts of the lattice but not the whole structure. In this paper, an estimation of the accuracy of XCT evaluation of a complete lattice structure in comparison to a higher-resolution reference device (FVM) is presented. Experimental measurements are taken on ad hoc designed test objects manufactured in polyamide 12 (PA12) using selective laser sintering (SLS), optimized for the evaluation on both instruments using different cubic-based lattice typologies. The results confirm higher precision on XCT evaluation in both qualitative and quantitative analysis. Even with a lower resolution, XCT is able to characterize details of the surface such as re-entrant features; as well, standard deviations and uncertainties in strut diameter evaluation remain more stable in all cells in XCT, identifying on the other hand reconstruction problems on FVM measurements. Moreover, it is shown that, using XCT, no additional evaluation errors were found in inner cells, suggesting that the measurement of external elements could be representative of the whole structure for metrological purposes. Full article

Effective emission control technologies and eco-friendly propulsion systems have been developed to decrease exhaust particle emissions. However, more work must be conducted on non-exhaust traffic-related sources such as tyre wear. The advent of automated vehicles (AVs) enables researchers and automotive manufacturers to consider ways to further decrease tyre wear, as vehicles will be controlled by the system rather than by the driver. In this direction, this work presents the formulation of an optimal control problem for the trajectory optimisation of automated articulated vehicles for tyre wear minimisation. The optimum velocity profile is sought for a predefined road path from a specific starting point to a final one to minimise tyre wear in fixed time cases. Specific boundaries and constraints are applied to the problem to ensure the vehicle’s stability and the feasibility of the solution. According to the results, a small increase in the journey time leads to a significant decrease in the mass loss due to tyre wear. The employment of articulated vehicles with low powertrain capabilities leads to greater tyre wear, while excessive increases in powertrain capabilities are not required. The conclusions pave the way for AV researchers and manufacturers to consider tyre wear in their control modules and come closer to the zero-emission goal. Full article

The accurate prediction of heavy precipitation in convective environments is crucial because such events, often occurring in Italy during the summer and fall seasons, can be a threat for people and properties. In this paper, we analyse the impact of satellite-derived surface-rainfall-rate data assimilation on the Weather Research and Forecasting (WRF) model’s precipitation prediction, considering 15 days in summer 2022 and 17 days in fall 2022, where moderate to intense precipitation was observed over Italy. A 3DVar realised at CNR-ISAC (National Research Council of Italy, Institute of Atmospheric Sciences and Climate) is used to assimilate two different satellite-derived rain rate products, both exploiting geostationary (GEO), infrared (IR), and low-Earth-orbit (LEO) microwave (MW) measurements: One is based on an artificial neural network (NN), and the other one is the operational P-IN-SEVIRI-PMW product (H60), delivered in near-real time by the EUMETSAT HSAF (Satellite Application Facility in Support of Operational Hydrology and Water Management). The forecast is verified in two periods: the hours from 1 to 4 (1–4 h phase) and the hours from 3 to 6 (3–6 h phase) after the assimilation. The results show that the rain rate assimilation improves the precipitation forecast in both seasons and for both forecast phases, even if the improvement in the 3–6 h phase is found mainly in summer. The assimilation of H60 produces a high number of false alarms, which has a negative impact on the forecast, especially for intense events (30 mm/3 h). The assimilation of the NN rain rate gives more balanced predictions, improving the control forecast without significantly increasing false alarms. Full article

A bacterium was isolated and identified from the secretion of a rhesus monkey with endometritis. The morphological results showed that the strain exhibited round, convex, gray-white colonies with smooth surfaces and diameters ranging from 1 to 2 mm when cultured on Columbia blood agar at 37 °C for 24 h; on salmonella–shigella agar (S.S.) at 37 °C for 24 h, the colonies appeared round, flat, and translucent. Gram staining showed negative results with blunt ends and non-spore-forming characteristics. Molecular biology results showed that the 16S rRNA sequence of the strain revealed over 96.9% similarity with published sequences of M. morganii from different sources in the NCBI GenBank database. Morphological and molecular biology analysis confirmed that the strain (RM2023) isolated from cervical secretions of rhesus monkey was M. morganii. Drug sensitivity testing demonstrated that the isolated strain (RM2023) was sensitive to ceftriaxone, amikacin, gentamicin, cefazolin, cefuroxime, ceftazidime, levofloxacin, cotrimoxazole, norfloxacin, and tetracycline; moderately sensitive to ampicillin; and resistant to penicillin, vancomycin, ciprofloxacin, and clindamycin. The research findings provide valuable insights for disease prevention in rhesus monkeys and contribute to molecular epidemiological studies. Full article