Charging stations and electric vehicle (EV) charging networks signify a significant advancement in technology as a frontier application of the Social Internet of Things (SIoT), presenting both challenges and opportunities for current 6G wireless networks. One primary challenge in this integration is limited wireless network resources, particularly when serving a large number of users within distributed EV charging networks in the SIoT. Factors such as congestion during EV travel, varying EV user preferences, and uncertainties in decision-making regarding charging station resources significantly impact system operation and network resource allocation. To address these challenges, this paper develops a novel framework harnessing the potential of emerging technologies, specifically reconfigurable intelligent surfaces (RISs) and causal-structure-enhanced asynchronous advantage actor–critic (A3C) reinforcement learning techniques. This framework aims to optimize resource allocation, thereby enhancing communication support within EV charging networks. Through the integration of RIS technology, which enables control over electromagnetic waves, and the application of causal reinforcement learning algorithms, the framework dynamically adjusts resource allocation strategies to accommodate evolving conditions in EV charging networks. An essential aspect of this framework is its ability to simultaneously meet real-world social requirements, such as ensuring efficient utilization of network resources. Numerical simulation results validate the effectiveness and adaptability of this approach in improving wireless network efficiency and enhancing user experience within the SIoT context. Through these simulations, it becomes evident that the developed framework offers promising solutions to the challenges posed by integrating the SIoT with EV charging networks. Full article

Objective: To analyze the performance of custom semi-automated software for quantitative analysis of retinal capillaries in eyes with macula-off rhegmatogenous retinal detachment (RRD) and the role of these microvascular measures as potential biomarkers of postoperative visual outcomes. Methods: A prospective, observational, and single-center study was conducted on consecutive patients who underwent 25G pars-plana vitrectomy for primary uncomplicated macula-off RRD. Optical coherence tomography angiography (OCTA) was performed in the fellow and RRD eyes before surgery and in months 1, 3, and 6 after surgery. The preoperative values of the fellow eyes were used as surrogates of macula-off ones. The primary endpoints were the mean vessel diameter index (VDI); vessel area density (VAD); and vessel skeleton density (VSD) at month 6. Results: Forty-four eyes (44 patients) were included in the study. Considering the fellow eyes as a surrogate of preoperative values of macula-off eyes, VDI in superficial (SCP) and deep (DCP) capillary plexuses was significantly reduced at month 6 (p = 0.0087 and p = 0.0402, respectively); whereas VSD in SCP increased significantly from preoperative values (p = 0.0278). OCTA built-in software parameters were significantly reduced from month 1 to month 6 in both SCP and DCP (p values ranged between 0.0235 and <0.0001). At month 6, 25 (56.8%) eyes achieved a best-corrected visual acuity BCVA ≥ 0.3 (LogMAR). The greater the preoperative BCVA, the greater the probability of achieving good visual outcomes (Odds ratio: 11.06; p = 0.0037). However, none of the OCTA parameters were associated with the probability of achieving a BCVA improvement ≥ 0.3. Conclusions: Quantitative evaluation of capillary density and morphology through OCTA and semi-automated software represents a valuable tool for clinical assessment and managing the disease comprehensively. Full article

The traditional aviary decontamination process involves farmers applying pesticides to the aviary’s ground. These agricultural defenses are easily dispersed in the air, making the farmers susceptible to chronic diseases related to recurrent exposure. Industry 5.0 raises new pillars of research and innovation in transitioning to more sustainable, human-centric, and resilient companies. Based on these concepts, this paper presents a new aviary decontamination process that uses IoT and a robotic platform coupled with ozonizer (O${}_3$) and ultraviolet light (UVL). These clean technologies can successfully decontaminate poultry farms against pathogenic microorganisms, insects, and mites. Also, they can degrade toxic compounds used to control living organisms. This new decontamination process uses physicochemical information from the poultry litter through sensors installed in the environment, which allows accurate and safe disinfection. Different experimental tests were conducted to construct the system. First, tests related to measuring soil moisture, temperature, and pH were carried out, establishing the range of use and the confidence interval of the measurements. The robot’s navigation uses a back-and-forth motion that parallels the aviary’s longest side because it reduces the number of turns, reducing energy consumption. This task becomes more accessible because of the aviaries’ standardized geometry. Furthermore, the prototype was tested in a real aviary to confirm the innovation, safety, and effectiveness of the proposal. Tests have shown that the UV + ozone combination is sufficient to disinfect this environment. Full article

Creating lightweight and impact-resistant box structures has been an enduring pursuit among researchers. A new energy-absorbing structure consisting of a bionic gradient lattice-enhanced thin-walled tube is presented in this article. The gradient lattice and thin-walled tube were prepared using selective laser melting (SLM) and wire-cutting techniques, respectively. To analyze the effects of gradient pattern, mass ratio, diameter range and impact speed on structural crashworthiness, low-speed impact at 4 m/s and finite element simulation experiments were conducted. The study demonstrates that the design of inward radial gradient lattice-reinforced thin-walled tubes can effectively enhance structure’s energy-absorption efficiency and provide a more stable mode of deformation. It also shows a 17.44% specific energy-absorption advantage over the uniformly lattice-reinforced thin-walled tubes, with no significant overall gain in peak crushing force. A complex scale evaluation method was used to determine the optimum structure and the structure type with the best crashworthiness was found to be a gradient lattice-filled tube with a thickness of 0.9 mm and a slope index of 10. The gradient lattice-reinforced thin-walled tube suggested in this investigation offers guidance for designing a more efficient thin-walled energy-absorption structure. Full article

Chicken feathers represent a viable material for producing biochar adsorbents. Traditional slow pyrolysis methods often result in sulfur element losses from chicken feathers, whereas hydrothermal reactions generate substantial amounts of nutrient-rich hydrothermal liquor. Magnesium-modified high-sulfur hydrochar MWF was synthesized through magnesium modification, achieving a S content of 3.68%. The maximum equilibrium adsorption amounts of MWF for Cd²⁺ and Pb²⁺ were 25.12 mg·g⁻¹ and 70.41 mg·g⁻¹, respectively, representing 4.00 times and 2.75 times of WF. Magnesium modification elevated the sulfur content, pH, ash content, and electronegativity of MWF. The primary mechanisms behind MWF’s adsorption of Cd²⁺ and Pb²⁺ involve magnesium ion exchange and complexation with C=O/O=C–O, quaternary N, and S functional groups. MWF maintains robust stability and antioxidative properties, even with low aromaticity levels. Given the lower energy consumption during hydrochar production, MWF offers notable carbon sequestration benefits. The hydrothermal solution derived from MWF is nutrient-rich. Following supplementation with inorganic fertilizer, the hydrothermal solution of MWF significantly enhanced bok choy growth compared to the control group. In general, adopting magnesium-modified hydrothermal reactions to produce hydrochar and converting the resultant hydrothermal solution into water-soluble fertilizer proves a viable strategy for the eco-friendly utilization of chicken feathers. This approach carries substantial value for heavy metal remediation and agricultural practices. Full article

The proximity of freshwater ecosystems to anthropogenic activities makes them one of the most threatened environments by plastic pollution in the form of microplastics (MPs). Therefore, it is crucial to identify the primary drivers of MP dynamics in rivers to enhance their management. This work analyzed the concentration of MPs in water and sediments and evaluated the influence of land use and its relationship with the main biotic indices employed to assess the water quality of rivers. This research was carried out in four different catchments, with three sampling points established in each river basin. The results revealed that MPs were ubiquitous across all locations, with concentrations ranging from 0.10 to 35.22 items m⁻³ in waters and from 26 to 643 items Kg⁻¹ in sediments. The highest concentration of MPs both in water and sediments were found in the Lagares River (35.22 items m⁻³ and 643 items Kg⁻¹), while the lowest concentrations were found in the Miñor River for water (0.10 items m⁻³) and Tea River for sediments (138 items Kg⁻¹). Urbanization degree was identified as the primary driver of MP pollution in water, whereas population density correlated with sediment pollution levels. These findings explain the elevated MPs abundance in the more urbanized and populated Gafos and Lagares rivers compared to the relatively pristine Miñor and Tea rivers. Furthermore, the presence of MPs in sediments was found to negatively impact the most sensitive benthic macroinvertebrate taxa, as evidenced by lower values of the IASPT and EPT indices at sampling points with higher sediment MPs concentrations (Gafos and Lagares). Full article

Quantum tunneling in a two-dimensional integrable map is studied. The orbits of the map are all confined to the curves specified by the one-dimensional Hamiltonian. It is found that the behavior of tunneling splitting for the integrable map and the associated Hamiltonian system is qualitatively the same, with only a slight difference in magnitude. However, the tunneling tails of the wave functions, obtained by superposing the eigenfunctions that form the doublet, exhibit significant differences. To explore the origin of the difference, we observe the classical dynamics in the complex plane and find that the existence of branch points appearing in the potential function of the integrable map could play the role of yielding non-trivial behavior in the tunneling tail. The result highlights the subtlety of quantum tunneling, which cannot be captured in nature only by the dynamics in the real plane. Full article

Wheelchair propulsion and actuation are influenced by the moving masses of the wheelchair user; however, the extent of this effect is still unclear. The main evidence of this effect is that the speed of the wheelchair frame continues to increase after the end of the push phase. The wheelchair’s speed was measured using IMUs and the duration of the push period was recorded using miniaturised pressure sensors attached to the driver’s middle fingers. The velocity and acceleration were determined for various average stroke cycle speeds to determine the speed dependency of the acceleration. The wheelchair was then mounted on a force plate to measure the inertial forces of the hands moving back and forth. The aerodynamic drag and rolling resistance forces were determined from coast-down experiments. Based on the measured forces, the behaviour of the force and velocity profiles was finally modelled by gradually reducing the mass of the arms and thus their inertial force. The results showed that the wheelchair is accelerated throughout the push phase (except for a temporary deceleration in the middle of the push phase at higher velocities), and that this acceleration continues well after the push phase. In the second half of the recovery phase, the wheelchair decelerates. The horizontal inertial forces measured on the force plate are predominantly negative in the push phase and in the second half of the recovery phase, and positive in the first half of the push phase, and their impulse is zero due to the conservation of momentum. Modelling the wheelchair with moving masses showed that reducing the horizontal inertial forces has no effect on the driver’s propulsive force but reduces the velocity fluctuations. The main conclusion of this research is that the wheelchair user’s power should be calculated only from the pure propulsive force that is required in the push phase to overcome the dissipative forces and that enables the gain or loss in speed per stroke cycle, but not directly from the measured velocity. Full article

Bcr-Abl is an oncoprotein with aberrant tyrosine kinase activity involved in the progression of chronic myeloid leukemia (CML) and has been targeted by inhibitors such as imatinib and nilotinib. However, despite their efficacy in the treatment of CML, a mechanism of resistance to these drugs associated with mutations in the kinase region has emerged. Therefore, in this work, we report the synthesis of 14 new 2,6,9-trisubstituted purines designed from our previous Bcr-Abl inhibitors. Here, we highlight 11b, which showed higher potency against Bcr-Abl (IC₅₀ = 0.015 μM) than imatinib and nilotinib and exerted the most potent antiproliferative properties on three CML cells harboring the Bcr-Abl rearrangement (GI₅₀ = 0.7–1.3 μM). In addition, these purines were able to inhibit the growth of KCL22 cell lines expressing Bcr-Abl^T315I, Bcr-Abl^E255K, and Bcr-Abl^Y253H point mutants in micromolar concentrations. Imatinib and nilotinib were ineffective in inhibiting the growth of KCL22 cells expressing Bcr-Abl^T315I (GI₅₀ > 20 μM) compared to 11b–f (GI₅₀ = 6.4–11.5 μM). Molecular docking studies explained the structure–activity relationship of these purines in Bcr-Abl^WT and Bcr-Abl^T315I. Finally, cell cycle cytometry assays and immunodetection showed that 11b arrested the cells in G1 phase, and that 11b downregulated the protein levels downstream of Bcr-Abl in these cells. Full article

Tracing the historical development of soil salinization and monitoring its current status are crucial for understanding the driving forces behind it, proposing strategies to improve soil quality, and predicting future trends. To comprehensively understand the evolution of research on the remote sensing inversion of soil salinity, a scientific bibliometric analysis was conducted on research from the past two decades indexed in the core scientific databases. This article analyzes the field from various perspectives, including the number of publications, authors, research institutions and countries, research fields, study areas, and keywords, in order to reveal the current state-of-the-art and cutting-edge research in this domain. Special attention was given to topics such as machine learning, data assimilation methods, unmanned aerial vehicle (UAV) remote sensing technology, soil inversion under vegetation cover, salt ion inversion, and remote sensing model construction methods. The results indicate an overall increase in the volume of publications, with key authors such as Metternicht, Gi and Zhao, Gengxing, and major research institutions including the International Institute for Geoinformatics Science and Earth Observation and the Chinese Academy of Sciences making significant contributions. Notably, China and the USA have made substantial contributions to this field, with research areas extending from Inner Mongolia’s Hetao irrigation district to the Mediterranean region. Research in the remote sensing domain focuses on various methods, including hyperspectral imaging for salinized soil inversion, with an increasing emphasis on machine learning. This study enriches researchers’ knowledge of the current trends and future directions of remote sensing inversion of soil salinization. Full article

In this paper, we prove the stability of the Brunn–Minkowski inequality for multiple convex bodies in terms of the concept of relative asymmetry. Using these stability results and the relationship of the compact support of functions, we establish the stability of the Borell–Brascamp–Lieb inequality for multiple power concave functions via relative asymmetry. Full article

This paper proposes a new framework to reduce the variance and uncertainty in the risk assessment process. Today, this process is susceptible to background noise from sources of human factor biases and erroneous measurements. Our new framework consists of deconstructing the likelihood of failure function into its sub-factor and then reconstructing it in a formula that can reduce the variance and biases of a human auditor judgment. We tested our new framework on both a questionnaire study and a simulation of the risk assessment process, and the improvement in reducing the variance is significant. Full article

Objectives: Sleeve gastrectomy (SG) is one of the most commonly performed weight loss (WL) bariatric procedures. The main goal of WL is reducing total body weight (TBW) and fat mass (FM). However, TBW loss is systematically accompanied by a decline in fat-free mass (FFM), predominantly in the first post-surgical month, despite protein supplementation. Branched-chain amino acids (BCAAs) and vitamin D seem to attenuate loss of FFM and, thus, reduce the decline in muscle strength (MS). However, data on the role of an integrated supplementation with whey protein plus BCAAs plus vitamin D (P+BCAAs+Vit.D) vs. protein alone on total weight loss (TWL), fat mass (FM), fat-free mass (FFM), and (MS) in the first month after SG are lacking. Therefore, the present study aims to evaluate the impact of P+BCAAs+Vit.D vs. protein alone supplementation on TWL, FM, FFM, and MS in the first month after SG. Materials and Methods: Before SG and at 1 month afterward, we prospectively measured and compared TBW, FM, FFM, and MS in 57 patients who received either a supplementation with P+BCAAs+Vit.D (n = 31) or protein alone (n = 26). The impact of P+BCAAs+Vit.D and protein alone supplementation on clinical status was also evaluated. Results: Despite non-significant variation in TBW, FM decreased more significantly (18.5% vs. 13.2%, p = 0.023) with the P+BCAA+Vit.D supplementation compared to protein alone. Furthermore, the P+BCAA+Vit.D group showed a significantly lower decrease in FFM (4.1% vs. 11.4%, p < 0.001) and MS (3.8% vs. 18.5%, p < 0.001) compared to the protein alone group. No significant alterations in clinical status were seen in either group. Conclusion: P+BCAA+Vit.D supplementation is more effective than protein alone in determining FM loss and is associated with a lower decrease in FFM and MS, without interfering with clinical status in patients 1 month after SG. Full article

(1) Background: This study evaluates the effectiveness of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) in improving gait in post-stroke hemiplegic patients, using wearable sensor technology for objective gait analysis. (2) Methods: A total of 72 stroke patients were randomized into control, sham stimulation, and LF-rTMS groups, with all receiving standard medical treatment. The LF-rTMS group underwent stimulation on the unaffected hemisphere for 6 weeks. Key metrics including the Fugl-Meyer Assessment Lower Extremity (FMA-LE), Berg Balance Scale (BBS), Modified Barthel Index (MBI), and gait parameters were measured before and after treatment. (3) Results: The LF-rTMS group showed significant improvements in the FMA-LE, BBS, MBI, and various gait parameters compared to the control and sham groups (p < 0.05). Specifically, the FMA-LE scores improved by an average of 5 points (from 15 ± 3 to 20 ± 2), the BBS scores increased by 8 points (from 35 ± 5 to 43 ± 4), the MBI scores rose by 10 points (from 50 ± 8 to 60 ± 7), and notable enhancements in gait parameters were observed: the gait cycle time was reduced from 2.05 ± 0.51 s to 1.02 ± 0.11 s, the stride length increased from 0.56 ± 0.04 m to 0.97 ± 0.08 m, and the walking speed improved from 35.95 ± 7.14 cm/s to 75.03 ± 11.36 cm/s (all p < 0.001). No adverse events were reported. The control and sham groups exhibited improvements but were not as significant. (4) Conclusions: LF-rTMS on the unaffected hemisphere significantly enhances lower-limb function, balance, and daily living activities in subacute stroke patients, with the gait parameters showing a notable improvement. Wearable sensor technology proves effective in providing detailed, objective gait analysis, offering valuable insights for clinical applications in stroke rehabilitation. Full article

The rapid development of additive manufacturing (AM) has facilitated the creation of bionic lightweight, energy-absorbing structures, enabling the implementation of more sophisticated internal structural designs. For protective structures, the utilization of artificially controlled deformation patterns can effectively reduce uncertainties arising from random structural damage and enhance deformation stability. This paper proposed a bionic corrugated lightweight honeycomb structure with controllable deformation. The force on the onset state of deformation of the overall structure was investigated, and the possibility of controlled deformation in the homogeneous structure was compared with that in the corrugated structure. The corrugated structures exhibited a second load-bearing capacity wave peak, with the load-bearing capacity reaching 60.7% to 117.29% of the first load-bearing peak. The damage morphology of the corrugated structure still maintained relative integrity. In terms of energy absorption capacity, the corrugated lightweight structure has a much stronger energy absorption capacity than the homogeneous structure due to the second peak of the load carrying capacity. The findings of this study suggested that the combination of geometric customization and longitudinal corrugation through additive manufacturing offers a promising approach for the development of high-performance energy-absorbing structures. Full article

The increase in responsibilities, together with the multiple challenges that students face in the university period, has a direct impact on their healthy lifestyles. This literature review describes the benefits of promoting healthy habits in college, highlighting the fundamental role of prevention and promotion. A systematic review was carried out following the PRISMA recommendations, searching for information in the WOS and Scopus databases. On the other hand, a search was carried out within the existing and available grey literature. The review focused on finding information about physical activity, nutrition, and stress (with an emphasis on resilience and academic burnout) in university students. This bibliographic review includes 32 articles and six web pages, containing information on the benefits of physical activity, healthy habits, and health prevention. The information collected in this study shows that university students are exposed to multiple changes during this period, increasing as the academic years progress. At that time, their habits worsen, with low adherence to the Mediterranean diet, low physical activity, and high levels of stress, specifically increasing cases of academic burnout. The establishment of healthy habits during the university period is necessary, observing an improvement in all the variables studied. Prevention has played a fundamental role. Full article

Assessments of changes in the ecological state of aquatic ecosystems are always burdened with uncertainty, which results from environmental reasons and poor repeatability of measurement results of elements enabling the assessment. This study determines the uncertainty related to the elements of the assessment of the hydroacoustic structure of fish communities’ (1) vertical target strength distribution (TS) in two-meter layers of water and (2) changes in the area where fish were recorded (which was determined on the basis of maps of their distribution in 2 m deep water layers). The object of this study was a lake (depth: 27 m) in which at the end of June 2016 the O₂ concentration was <1.4 mg L⁻¹ below 8 m depth, which resulted in the accumulation of fish to a depth of 6 m. Hydroacoustic acquisition was carried out along transects arranged in the east–west (WE), north–south (NS), and zigzag (ZZ) directions in three repetitions. It was shown that the empirical probability of obtaining statistically different results was 2/9 when (1) Kendall’s τ coefficient, used to determine the similarity of the TS distribution, was less than 0.7—moderate correlation—and (2) fish occurrence areas in two cases (WE and ZZ on the third day of research) in layers 2–4 m and 4–6 m differed statistically significantly from the average area for all repetitions by 10–14% and 56–66% (p < 0.05), respectively. The obtained results indicate quite good repeatability of acoustic measurements; however, in order to reduce the uncertainty, it is recommended that tests be conducted in this type of lake in three series of measurements. Full article

Based on the actual situation of the project on the Weihai–Yanhai Expressway section of Rongwu Expressway, the effects of water content change and the dry–wet cycle on the mechanical behavior of unsaturated clayey sandy soil were analyzed in this study. In this study, ventilated undrained triaxial shear tests were carried out on unsaturated clayey sandy soils with different water contents (6%, 8%, 10%, 12%, 14% and 16%). Concurrently, the soil samples were subjected to three distinct wet and dry cycle pathways (2~22%, 2~12%, and 12~22%) to gain an understanding of how the mechanical features of the soil changed under the different conditions. The test findings demonstrate that when the water content increases, the unsaturated clayey sandy soil’s cohesiveness and shear strength diminish. The strength of shear decline exhibits a pattern of first being quick, followed by sluggish. The strength of shear and cohesiveness of clayey sandy soil declined under the influence of the dry and wet cycles, with the first cycle primarily affecting variations in cohesiveness and strength of shear. Furthermore, the strength of shear and cohesiveness of clayey sandy soil diminish more with increasing wet and dry cycle amplitude and upper water content limits. Lastly, the drying shrinkage and hygroscopic expansion of clay particles in clayey sandy soils during wet and dry cycles are not significant, resulting in less structural damage and deterioration of the mechanical properties of the soils. The study’s findings have a significant impact on the durability of roadbeds made of unsaturated clayey sandy soil in both wet and dry situations. Full article

Plankton studies serve as a basis for marine ecosystem research, but knowledge of marine plankton is still incomplete due to its extreme taxonomic and functional complexity. The application of metabarcoding is very valuable for the characterisation of the plankton community. The plankton community of the Southern Adriatic is subject to strong environmental fluctuations and changes, which underlines the need for frequent, reliable and comprehensive characterisation of the plankton. The aim of this study was to determine the taxonomic composition and seasonal distribution of eukaryotic plankton in the Southern Adriatic. Plankton samples were collected monthly for one year at the coastal station of the Southern Adriatic and metabarcoding was used for taxonomic identification. The results showed a high taxonomic diversity and dynamic seasonal distribution patterns for both the protist and metazoan plankton communities. Metabarcoding revealed both the core, year-round plankton community and previously unrecorded plankton organisms in the Southern Adriatic. The results provide for the first time a comprehensive overview of the plankton community in this area by metabarcoding. The identified seasonal patterns of plankton genera and species in the Southern Adriatic will contribute to the understanding of plankton interactions and future changes in community diversity characterisation. Full article

Pathological cleavage of type II collagen (Col2) and generation of Col2 neoepitopes can serve as useful molecular markers of the progression of osteoarthritis (OA). One of such potential biomarkers is type II collagen neoepitope C2C. The aim of this study was to correlate the degree of articular cartilage damage in OA patients with C2C expression in histological samples of tissues removed during total knee replacement. Cartilage samples were obtained from 27 patients ranging in age from 55 to 66 years. In each patient, medial and lateral tibia plateau samples were analyzed according to the OARSI histopathology grading system. The C2C expression was evaluated on histological slides by semi-quantitative analysis using ImageJ Fiji 2.14.0 software. Spearman’s rank correlation analysis revealed a positive weak correlation (rho = 0.289, p = 0.0356) between the histological grade of tissue damage and the percentage of C2C staining. In addition, a highly significant positive correlation (rho = 0.388, p = 0.0041) was discovered between the osteoarthritis score (combining the histological grade of damage with the OA macroscopic stage) and the percentage of C2C staining in the samples. The C2C expression was detected in all the regions of the articular cartilage (i.e., the superficial zone, mid zone, deep zone and tidemark area, and the zone of calcified cartilage). Our findings imply that local expression of C2C correlates with the articular cartilage damage in OA-affected knees. This confirms that C2C can be used as a prospective marker for assessing pathological changes in the OA course and OA clinical trials. Full article