The 2023 MDPI Annual Report has
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18 pages, 1920 KiB  
Article
Obtaining Bixin- and Tocotrienol-Rich Extracts from Peruvian Annatto Seeds Using Supercritical CO2 Extraction: Experimental and Economic Evaluation
by Fiorella P. Cárdenas-Toro, Jennifer H. Meza-Coaquira, Gabriela K. Nakama-Hokamura and Giovani Leone Zabot
Foods 2024, 13(10), 1549; https://doi.org/10.3390/foods13101549 (registering DOI) - 16 May 2024
Abstract
Currently, Bixa orellana L. extracts are used as a color source in the food, pharmaceutical, and cosmetic industries because they are important as a potential source of antioxidant activity. The extraction is carried out by conventional methods, using alkaline solutions or organic solvents. [...] Read more.
Currently, Bixa orellana L. extracts are used as a color source in the food, pharmaceutical, and cosmetic industries because they are important as a potential source of antioxidant activity. The extraction is carried out by conventional methods, using alkaline solutions or organic solvents. These extraction methods do not take advantage of the lipid fraction of annatto (Bixa orellana L.) seeds, and the process is not friendly to the environment. In this work, the objective was to obtain an extract rich in nutraceuticals (bixin and tocols) of high antioxidant power from Peruvian annatto seeds as a potential source for a functional food or additive in the industry using supercritical fluid extraction (SFE). Experiments related to extraction yield, bixin, tocotrienols, tocopherols, and antioxidant activity were carried out. The SFE was performed at 40 °C, 50 °C, and 60 °C, and 100, 150, and 250 bar with 0.256 kg/h carbon dioxide as the supercritical solvent (solvent-to-feed ratio of 10.2). Supercritical extraction at 60 °C and 250 bar presented the best results in terms of global extraction yield of 1.40 ± 0.01 g/100 g d.b., extract concentration of 0.564 ± 0.005 g bixin/g extract, 307.8 mg α-tocotrienol/g extract, 39.2 mg β-tocotrienol/g extract, 2 mg γ-tocopherol/g extract, and IC50 of 989.96 μg extract/mL. Economical evaluation showed that 60 °C, 250 bar, and 45 min presented the lowest cost of manufacturing (2 × 2000 L, COM of USD 212.39/kg extract). This extract is a potential source for functional food production. Full article
(This article belongs to the Special Issue Application of Green Extraction Technology for Foods)
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12 pages, 1895 KiB  
Review
Acute Myocardial Infarction in COVID-19 Patients—A Review of Literature Data and Two-Case Report Series
by Luiza Nechita, Elena Niculet, Liliana Baroiu, Alexia Anastasia Stefania Balta, Aurel Nechita, Doina Carina Voinescu, Corina Manole, Camelia Busila, Mihaela Debita and Alin Laurentiu Tatu
J. Clin. Med. 2024, 13(10), 2936; https://doi.org/10.3390/jcm13102936 (registering DOI) - 16 May 2024
Abstract
Background/Objectives: The newly emergent COVID-19 pandemic involved primarily the respiratory system and had also major cardiovascular system (CVS) implications, revealed by acute myocardial infarction (AMI), arrhythmias, myocardial injury, and thromboembolism. CVS involvement is done through main mechanisms—direct and indirect heart muscle injury, [...] Read more.
Background/Objectives: The newly emergent COVID-19 pandemic involved primarily the respiratory system and had also major cardiovascular system (CVS) implications, revealed by acute myocardial infarction (AMI), arrhythmias, myocardial injury, and thromboembolism. CVS involvement is done through main mechanisms—direct and indirect heart muscle injury, with high mortality rates, worse short-term outcomes, and severe complications. AMI is the echo of myocardial injury (revealed by increases in CK, CK-MB, and troponin serum markers—which are taken into consideration as possible COVID-19 risk stratification markers). When studying myocardial injury, physicians can make use of imaging studies, such as cardiac MRI, transthoracic (or transesophageal) echocardiography, coronary angiography, cardiac computed tomography, and nuclear imaging (which have been used in cases where angiography was not possible), or even endomyocardial biopsy (which is not always available or feasible). Two-case-series presentations: We present the cases of two COVID-19 positive male patients who were admitted into the Clinical Department of Cardiology in “Sfântul Apostol Andrei” Emergency Clinical Hospital of Galați (Romania), who presented with acute cardiac distress symptoms and have been diagnosed with ST elevation AMI. The patients were 82 and 57 years old, respectively, with moderate and severe forms of COVID-19, and were diagnosed with anteroseptal left ventricular AMI and extensive anterior transmural left ventricular AMI (with ventricular fibrillation at presentation), respectively. The first patient was a non-smoker and non-drinker with no associated comorbidities, and was later discharged, while the second one died due to AMI complications. Conclusions: From this two-case series, we extract the following: old age alone is not a significant risk factor for adverse outcomes in COVID-19-related CVS events, and that the cumulative effects of several patient-associated risk factors (be it either for severe forms of COVID-19 and/or acute cardiac injury) will most probably lead to poor patient prognosis (death). At the same time, serum cardiac enzymes, dynamic ECG changes, along with newly developed echocardiographic modifications are indicators for poor prognosis in acute cardiac injury in COVID-19 patients with acute myocardial injury, regardless of the presence of right ventricular dysfunction (due to pulmonary hypertension). Full article
(This article belongs to the Section Cardiovascular Medicine)
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16 pages, 9701 KiB  
Article
Compact Quantum Random Number Generator Based on a Laser Diode and a Hybrid Chip with Integrated Silicon Photonics
by Xuyang Wang, Tao Zheng, Yanxiang Jia, Jin Huang, Xinyi Zhu, Yuqi Shi, Ning Wang, Zhenguo Lu, Jun Zou and Yongmin Li
Photonics 2024, 11(5), 468; https://doi.org/10.3390/photonics11050468 (registering DOI) - 16 May 2024
Abstract
In this study, a compact and low-power-consumption quantum random number generator (QRNG) based on a laser diode and a hybrid chip with integrated silicon photonics is proposed and verified experimentally. The hybrid chip’s size is 8.8 × 2.6 × 1 mm3, [...] Read more.
In this study, a compact and low-power-consumption quantum random number generator (QRNG) based on a laser diode and a hybrid chip with integrated silicon photonics is proposed and verified experimentally. The hybrid chip’s size is 8.8 × 2.6 × 1 mm3, and the power of the entropy source is 80 mW. A common-mode rejection ratio greater than 40 dB was achieved using an optimized 1 × 2 multimode interferometer structure. A method for optimizing the quantum-to-classical noise ratio is presented. A quantum-to-classical noise ratio of approximately 9 dB was achieved when the photoelectron current is 1 μA using a balance homodyne detector with a high dark current GeSi photodiode. The proposed QRNG has the potential for use in scenarios of moderate MHz random number generation speed, with low power, small volume, and low cost prioritized. Full article
(This article belongs to the Topic Hybrid and Heterogeneous Integration on Photonic Circuits)
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20 pages, 8717 KiB  
Article
Investigation of Surface Integrity of 304 Stainless Steel in Turning Process with Nanofluid Minimum-Quantity Lubrication Using h-BN Nanoparticles
by Min Fu, Guangchun Xiao, Hui Chen, Jingjie Zhang, Mingdong Yi, Zhaoqiang Chen and Chonghai Xu
Metals 2024, 14(5), 583; https://doi.org/10.3390/met14050583 (registering DOI) - 16 May 2024
Abstract
This paper investigates the influence of the concentration and particle size of h-BN nanoparticles in a nanofluid on the surface integrity of 304 austenitic stainless steel during turning, focusing on the cutting force, friction coefficient, cutting temperature, surface roughness, surface residual stress, work [...] Read more.
This paper investigates the influence of the concentration and particle size of h-BN nanoparticles in a nanofluid on the surface integrity of 304 austenitic stainless steel during turning, focusing on the cutting force, friction coefficient, cutting temperature, surface roughness, surface residual stress, work hardening capacity, and 3D surface topography. The results show that, compared to dry cutting, the addition of 3 wt.% h-BN nanofluid can reduce the friction coefficient on the rake face by 38.9%, lower the cutting temperature by 43.5%, decrease the surface roughness by 53.8%, decrease the surface residual stress by 61.6%, and reduce the work hardening degree by 27.5%. Two-dimensional profiles and the 3D surface topography display a more balanced peak–valley distribution. Furthermore, by studying the effect of different h-BN particle sizes in nanofluids on the surface integrity of the machined workpiece, it was found that nanoscale particles have a greater tendency to penetrate the tool–chip interface than submicron particles. Moreover, the h-BN particles in the nanofluid play a “rolling effect” and “microsphere” effect, and the sesame oil will also form a lubricating oil film in the knife-chip contact area, thereby reducing the friction coefficient, reducing the cutting force, and improving the machining surface quality. Full article
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18 pages, 453 KiB  
Article
Efficient IoT-Assisted Waste Collection for Urban Smart Cities
by Sangrez Khan, Bakhtiar Ali, Abeer A. K. Alharbi, Salihah Alotaibi and Mohammed Alkhathami
Sensors 2024, 24(10), 3167; https://doi.org/10.3390/s24103167 (registering DOI) - 16 May 2024
Abstract
Waste management is one of the many major challenges faced by all urban cities around the world. With the increase in population, the current mechanisms for waste collection and disposal are under strain. The waste management problem is a global challenge that requires [...] Read more.
Waste management is one of the many major challenges faced by all urban cities around the world. With the increase in population, the current mechanisms for waste collection and disposal are under strain. The waste management problem is a global challenge that requires a collaborative effort from different stakeholders. Moreover, there is a need to develop technology-based solutions besides engaging the communities and establishing novel policies. While there are several challenges in waste management, the collection of waste using the current infrastructure is among the top challenges. Waste management suffers from issues such as a limited number of collection trucks, different types of household and industrial waste, and a low number of dumping points. The focus of this paper is on utilizing the available waste collection transportation capacity to efficiently dispose of the waste in a time-efficient manner while maximizing toxic waste disposal. A novel knapsack-based technique is proposed that fills the collection trucks with waste bins from different geographic locations by taking into account the amount of waste and toxicity in the bins using IoT sensors. Using the Knapsack technique, the collection trucks are loaded with waste bins up to their carrying capacity while maximizing their toxicity. The proposed model was implemented in MATLAB, and detailed simulation results show that the proposed technique outperforms other waste collection approaches. In particular, the amount of high-priority toxic waste collection was improved up to 47% using the proposed technique. Furthermore, the number of waste collection visits is reduced in the proposed scheme as compared to the conventional method, resulting in the recovery of the equipment cost in less than a year. Full article
(This article belongs to the Special Issue Smart Cities: Sensors and IoT)
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14 pages, 8726 KiB  
Article
Human-Unrecognizable Differential Private Noised Image Generation Method
by Hyeong-Geon Kim, Jinmyeong Shin and Yoon-Ho Choi
Sensors 2024, 24(10), 3166; https://doi.org/10.3390/s24103166 (registering DOI) - 16 May 2024
Abstract
Differential privacy has emerged as a practical technique for privacy-preserving deep learning. However, recent studies on privacy attacks have demonstrated vulnerabilities in the existing differential privacy implementations for deep models. While encryption-based methods offer robust security, their computational overheads are often prohibitive. To [...] Read more.
Differential privacy has emerged as a practical technique for privacy-preserving deep learning. However, recent studies on privacy attacks have demonstrated vulnerabilities in the existing differential privacy implementations for deep models. While encryption-based methods offer robust security, their computational overheads are often prohibitive. To address these challenges, we propose a novel differential privacy-based image generation method. Our approach employs two distinct noise types: one makes the image unrecognizable to humans, preserving privacy during transmission, while the other maintains features essential for machine learning analysis. This allows the deep learning service to provide accurate results, without compromising data privacy. We demonstrate the feasibility of our method on the CIFAR100 dataset, which offers a realistic complexity for evaluation. Full article
(This article belongs to the Section Intelligent Sensors)
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19 pages, 1642 KiB  
Article
A Lightweight Secure Scheme for Underwater Wireless Acoustic Network
by Jia Shi, Jinqiu Wu, Zhiwei Zhao, Xiaofei Qi, Wenbo Zhang, Gang Qiao and Dahong Zuo
J. Mar. Sci. Eng. 2024, 12(5), 831; https://doi.org/10.3390/jmse12050831 (registering DOI) - 16 May 2024
Abstract
Due to the open underwater channels and untransparent network deployment environments, underwater acoustic networks (UANs) are more vulnerable to hostile environments. Security research is also being conducted in cryptography, including authentication based on asymmetric algorithms and key distribution based on symmetric algorithms. In [...] Read more.
Due to the open underwater channels and untransparent network deployment environments, underwater acoustic networks (UANs) are more vulnerable to hostile environments. Security research is also being conducted in cryptography, including authentication based on asymmetric algorithms and key distribution based on symmetric algorithms. In recent years, the advancement of quantum computing has made anti-quantum attacks an important issue in the field of security. Algorithms such as lattice and SPHINCS+ have become a research topic of interest in the field of security. However, within the past five years, few papers have discussed security algorithms for UANs to resist quantum attacks, especially through classical algorithms. Some existing classical asymmetric and symmetric algorithms are considered to have no prospects. From the perspective of easy deployment in engineering and anti-quantum attacks, our research focuses on a comprehensive lightweight security framework for data protection, authentication, and malicious node detection through the Elliptic Curve and Hash algorithms. Our mechanism is suitable for ad hoc scenarios with limited underwater resources. Meanwhile, we have designed a multi-party bit commitment to build a security framework for the system. A management scheme is designed by combining self-certifying with the threshold sharing algorithm. All schemes are designed based on certificate-less and ad hoc features. The proposed scheme ensures that the confidentiality, integrity, and authentication of the system are well considered. Moreover, the scheme is proven to be of unconditional security and immune to channel eavesdropping. The resource and delay issues are also taken into consideration. The simulations considered multiple variables like number of nodes, attackers, and message length to calculate proper values that can increase the efficiency of this scheme. The results in terms of delay, delivery ratio, and consumption demonstrate the suitability of the proposal in terms of security, especially for malicious node detection. Meanwhile, the computational cost has also been controlled at the millisecond level. Full article
(This article belongs to the Special Issue Safety and Reliability of Ship and Ocean Engineering Structures)
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24 pages, 15036 KiB  
Article
A Combined Seasonal Mann–Kendall and Innovative Approach for the Trend Analysis of Streamflow Rate in Two Croatian Rivers
by Mehmet Berkant Yıldız, Fabio Di Nunno, Bojan Đurin, Quoc Bao Pham, Giovanni de Marinis and Francesco Granata
Water 2024, 16(10), 1422; https://doi.org/10.3390/w16101422 (registering DOI) - 16 May 2024
Abstract
Climate change profoundly impacts hydrological systems, particularly in regions such as Croatia, which is renowned for its diverse geography and climatic variability. This study examined the effect of climate change on streamflow rates in two Croatian rivers: Bednja and Gornja Dobra. Using seasonal [...] Read more.
Climate change profoundly impacts hydrological systems, particularly in regions such as Croatia, which is renowned for its diverse geography and climatic variability. This study examined the effect of climate change on streamflow rates in two Croatian rivers: Bednja and Gornja Dobra. Using seasonal Mann–Kendall (MK) tests, overall streamflow trends were evaluated. Additionally, innovative polygon trend analysis (IPTA), innovative visualization for innovative trend analysis (IV-ITA), and Bayesian changepoint detection and time series decomposition (BEAST) algorithms were used to assess the trends’ magnitudes and transitions. The seasonal MK analysis identified significant decreasing trends, primarily during summer. The results of IPTA and IV-ITA revealed consistent decreasing trends throughout most months, with a notable increase in September, especially at high flow values. The rivers’ behavior differed between the first and second halves of the month. BEAST analysis detected abrupt changes, including earlier shifts (1951–1968) in the Bednja and more recent ones (2013–2015) in both the Bednja and, to a lesser extent, the Gornja Dobra rivers. This comprehensive approach enhances our understanding of long-term streamflow trends and short-term fluctuations induced by climate change. Full article
(This article belongs to the Special Issue Advances in Hydrology: Flow and Velocity Analysis in Rivers)
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28 pages, 2664 KiB  
Article
Getting Ready for Multi-Vendor and Multi-Terminal HVDC Technology
by Jaqueline Cabañas Ramos, Marc Moritz, Nico Klötzl, Ceciel Nieuwenhout, William Leon Garcia, Ilka Jahn, Dimitar Kolichev and Antonello Monti
Energies 2024, 17(10), 2388; https://doi.org/10.3390/en17102388 (registering DOI) - 16 May 2024
Abstract
Interoperable multi-vendor High-Voltage Direct-Current (HVDC) grids are a key enabler for the integration of renewable energy (in particular offshore wind) and its transmission over longer distances to consumers. However, most HVDC systems today are single-vendor and point-to-point. Various technical and non-technical aspects need [...] Read more.
Interoperable multi-vendor High-Voltage Direct-Current (HVDC) grids are a key enabler for the integration of renewable energy (in particular offshore wind) and its transmission over longer distances to consumers. However, most HVDC systems today are single-vendor and point-to-point. Various technical and non-technical aspects need to be considered, for example, (real-time) testing, legal aspects (intellectual property and regulation), and the multi-vendor interoperability process. This paper presents findings from the READY4DC project, which is a larger and open European effort involving diverse stakeholders, including HVDC manufacturers, transmission system operators, wind developers, academia, and research institutes. It summarizes key technical recommendations, emphasizing comprehensive interaction studies and the development of a structured legal framework to facilitate the development and operation of a multi-vendor, multi-terminal HVDC grid. The READY4DC project highlights the need for increased harmonization, transparent communication among stakeholders, and future-oriented research to ensure the robustness and interoperability of interconnected grids. Collaborative efforts are key for addressing technical complexities and advancing the deployment of multi-vendor multi-terminal HVDC technology. Full article
(This article belongs to the Section F1: Electrical Power System)
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12 pages, 2402 KiB  
Article
One-Step Synthesis of High-Efficiency Oxygen Evolution Reaction Catalyst FeSx(Y/MB) with High Temperature Resistance and Strong Alkali
by Jing Wang, Lingling Feng, Zikang Zhao, Yan Wang, Ying Zhang, Shan Song, Shengwei Sun, Junshuang Zhou and Faming Gao
Catalysts 2024, 14(5), 324; https://doi.org/10.3390/catal14050324 (registering DOI) - 16 May 2024
Abstract
Given the energy crisis and escalating environmental pollution, the imperative for developing clean new energy is evident. Hydrogen has garnered significant attention owing to its clean properties, high energy density, and ease of storage and transportation. This study synthesized four types of catalysts—FeS(DI/MB), [...] Read more.
Given the energy crisis and escalating environmental pollution, the imperative for developing clean new energy is evident. Hydrogen has garnered significant attention owing to its clean properties, high energy density, and ease of storage and transportation. This study synthesized four types of catalysts—FeS(DI/MB), FeS(ET/MB), Fe(DI/MB), and Fe(ET/MB)—using two distinct solution systems: DI/MB and ET/MB. The FeS(DI/MB) catalyst, synthesized using the layered solution system (DI/MB), demonstrates a uniformly distributed and dense nanosheet structure, exhibiting excellent resistance to strong bases and superior catalytic properties. The FeS(DI/MB) electrode showed OER overpotentials of 460 mV and 318 mV in 1 M and 6 M, respectively, at current densities of up to 500 mA cm−2. Under industrial electrolysis test conditions, the FeS(DI/MB) electrode required only 262 mV to achieve a current density of 500 mA cm−2, operating in a high-temperature, strong alkaline environment of 6 M at 60 °C. Furthermore, the FeS(DI/MB) electrode exhibited excellent OER catalytic activity and stability, as evidenced by a 60 h stability test These findings provide valuable insights into the preparation of iron nickel sulfide-based catalysts, and further in-depth and comprehensive exploration is anticipated to yield the excellent catalytic performance of these catalysts in the realm of electrolytic water hydrogen production. Full article
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17 pages, 5877 KiB  
Article
Numerical Analyses of the Effect of the Freezing Wall on Ground Movement in the Artificial Ground Freezing Method
by Yazhou Ou, Long Wang, Hui Bian, Hua Chen, Shaole Yu, Tao Chen, Alfrendo Satyanaga and Qian Zhai
Appl. Sci. 2024, 14(10), 4220; https://doi.org/10.3390/app14104220 (registering DOI) - 16 May 2024
Abstract
The advancement of massive construction in urban subway projects contributes to the increased use of the artificial ground freezing (AGF) method in the construction of cross passages due to its reliability and environmental friendliness. However, the uplift or subsidence of the ground surface [...] Read more.
The advancement of massive construction in urban subway projects contributes to the increased use of the artificial ground freezing (AGF) method in the construction of cross passages due to its reliability and environmental friendliness. However, the uplift or subsidence of the ground surface induced by the frost heave and thawing settlement of the soil can be a problem for existing buildings, and the current design method places way too much emphasis on the strength requirement of the freezing wall. In this study, FLAC3D was employed to develop a series of state-of-the-art numerical models of the construction of a typical subway cross passage by the AGF method, utilizing freezing walls with different thicknesses. The results of this study can be used to examine the ground deformation arising from the AGF method and the influence of the thickness of the freezing wall on the AGF method. Full article
(This article belongs to the Special Issue Artificial Ground Freezing Technology)
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19 pages, 2537 KiB  
Article
Energy Efficiency Analysis of Waste-to-Energy Plants in Poland
by Marian Banaś, Tadeusz Pająk, Jakub Bator, Wojciech Wróbel and Józef Ciuła
Energies 2024, 17(10), 2390; https://doi.org/10.3390/en17102390 (registering DOI) - 16 May 2024
Abstract
The issue of enhancing energy recovery efficiency is a key concern within the European Union’s climate protection efforts. In particular, it applies to all processes and plants for the harvesting, gathering, and conversion of energy. The abandonment of fossil fuels in favour of [...] Read more.
The issue of enhancing energy recovery efficiency is a key concern within the European Union’s climate protection efforts. In particular, it applies to all processes and plants for the harvesting, gathering, and conversion of energy. The abandonment of fossil fuels in favour of alternative energy sources, and the increasing of energy efficiency and its recovery, is now a widely accepted direction of energy development. This study focuses on facilities that recover and process energy from municipal waste left after recycling processes, known as waste-to-energy (WtE) plants. These plants’ energy recovery efficiency is governed by the R1 Formula in EU countries. This report is based on an analysis of four years of operational data from selected Polish municipal waste incinerators, supplemented by a discussion of various studies on energy recovery efficiency. The primary objective of this report is to evaluate the effectiveness of these plants in contributing to sustainable waste management and energy recovery. The main effect of the developed report is the set of results of the energy recovery efficiency factor values, determined based on the R1 formula valid in the EU legislation, tabulated and graphically illustrated, and calculated for five selected Polish waste-to-energy plants. The presented results, with their graphical interpretation, discussion, and conclusions, provide insights into several factors influencing the value of the R1 efficiency factor. They can be a valuable contribution to operators of waste-to-energy plants, especially those operating in countries outside the EU. Full article
(This article belongs to the Section B: Energy and Environment)
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27 pages, 1982 KiB  
Article
Current Perceptions of Virtual Reality Technology
by Rebecca L. Hornsey and Paul B. Hibbard
Appl. Sci. 2024, 14(10), 4222; https://doi.org/10.3390/app14104222 (registering DOI) - 16 May 2024
Abstract
User experience is a key predictor of future use of goods and services. The presented study collected a combination of qualitative and quantitative data from both experienced users and novices about their perceptions of virtual reality (VR) equipment, any concerns surrounding the data [...] Read more.
User experience is a key predictor of future use of goods and services. The presented study collected a combination of qualitative and quantitative data from both experienced users and novices about their perceptions of virtual reality (VR) equipment, any concerns surrounding the data collected by the equipment, and facets that needed to be taken into consideration for future developments. The purpose of this research was to understand the current user experience of VR and ways in which it can be improved. The findings indicated that the majority of people have used VR, albeit infrequently, and that the most common use for it was for entertainment purposes. The most important characteristics of VR systems were judged to be the available content and price. While it was reported to be enjoyable to use, the ways in which it was suggested to be improved were through a reduction in size and weight of the headsets, and incorporating wireless capabilities. Concerns about the use of VR were the potential for sickness, discomfort, and eye strain, the disconnect from the real world and the subsequent risks that this poses, as well as the use and privacy of user data. The findings from this research can be used as a stepping stone toward the advancement of VR technologies. Full article
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18 pages, 907 KiB  
Article
Optimizing Spatial Layout of Campsites for Self-Driving Tours in Xinjiang: A Study Based on Online Travel Blog Data
by Xiaomin Dai and Qihang Zhang
Sustainability 2024, 16(10), 4176; https://doi.org/10.3390/su16104176 (registering DOI) - 16 May 2024
Abstract
Within the economic and cultural context of Xinjiang, the tourism industry has rapidly developed as a strategic pillar of the national economy, with the self-driving tour market emerging prominently. However, the uneven spatial layout and insufficient service facilities of self-driving camps limit their [...] Read more.
Within the economic and cultural context of Xinjiang, the tourism industry has rapidly developed as a strategic pillar of the national economy, with the self-driving tour market emerging prominently. However, the uneven spatial layout and insufficient service facilities of self-driving camps limit their development potential. This study aims to enhance the attractiveness of tourism in Xinjiang and improve the visitor service experience by constructing an evaluation system for the layout of self-driving camps based on online travel blog data, utilizing methods such as literature review, surveys, ArcGIS spatial analysis, and web text analysis. The Delphi method and entropy weight method were applied to determine the weights of the influencing factors. The findings reveal spatial imbalances in the layout of Xinjiang’s self-driving camps and propose eight preferred scenic areas for camp location. This study also suggests sustainable development strategies. These insights and recommendations aim to optimize the layout of self-driving camps, enhance the tourism experience, and promote the sustainable development of Xinjiang’s tourism industry. Full article
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13 pages, 5541 KiB  
Article
Solid–Liquid Two-Phase Flowmeter Flow-Passage Wall Erosion Evolution Characteristics and Calibration of Measurement Accuracy
by Wei Han, Lumin Yan, Rennian Li, Jing Zhang, Xiang Yang, Lei Ji and Yan Qiang
Processes 2024, 12(5), 1012; https://doi.org/10.3390/pr12051012 (registering DOI) - 16 May 2024
Abstract
Solid–liquid two-phase flowmeters are widely used in critical sectors, such as petrochemicals, energy, manufacturing, the environment, and various other fields. They are indispensable devices for measuring flow. Currently, research has primarily focused on gas–liquid two-phase flow within the flowmeter, giving limited attention to [...] Read more.
Solid–liquid two-phase flowmeters are widely used in critical sectors, such as petrochemicals, energy, manufacturing, the environment, and various other fields. They are indispensable devices for measuring flow. Currently, research has primarily focused on gas–liquid two-phase flow within the flowmeter, giving limited attention to the impact of solid phases. In practical applications, crude oil frequently contains solid particles and other impurities, leading to equipment deformation and a subsequent reduction in measuring accuracy. This paper investigates how particle dynamic parameters affect the erosion evolution characteristics of flowmeters operating in solid–liquid two-phase conditions, employing the dynamic boundary erosion prediction method. The results indicate that the erosion range and peak erosion position on the overcurrent wall of the solid–liquid two-phase flowmeter vary with different particle dynamic parameters. Erosion mainly occurs at the contraction section of the solid–liquid two-phase flowmeter. When the particle inflow velocity increases, the erosion range shows no significant change, but the peak erosion position shifts to the right, primarily due to the evolution of the erosion process. With an increase in particle diameter, the erosion range expands along the inlet direction due to turbulent diffusion, as particles with lower kinetic energy exhibit better followability. There is no significant change in the erosion range and peak erosion position with an increase in particle volume fraction and particle sphericity. With a particle inflow velocity of 8.4 m/s, the maximum erosion depth reaches 750 μm. In contrast, at a particle sphericity of 0.58, the minimum erosion depth is 251 μm. Furthermore, a particle volume fraction of 0.5 results in a maximum flow coefficient increase of 1.99 × 10−3. Full article
(This article belongs to the Special Issue New Research on Oil and Gas Equipment and Technology)
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13 pages, 7428 KiB  
Article
Effects of Strain Rate on the GND Characteristics of Deformed Polycrystalline Pure Copper
by Yidan Ma, Guisen Liu, Shuqing Yang, Ran Chen, Shuopeng Xu and Yao Shen
Metals 2024, 14(5), 582; https://doi.org/10.3390/met14050582 (registering DOI) - 16 May 2024
Abstract
Geometrically necessary dislocations (GNDs) play a pivotal role in polycrystalline plastic deformation, with their characteristics notably affected by strain rate and other factors, but the underlying mechanisms are not well understood yet. We investigate GND characteristics in pure copper polycrystals subjected to tensile [...] Read more.
Geometrically necessary dislocations (GNDs) play a pivotal role in polycrystalline plastic deformation, with their characteristics notably affected by strain rate and other factors, but the underlying mechanisms are not well understood yet. We investigate GND characteristics in pure copper polycrystals subjected to tensile deformation at varying strain rates (0.001 s−1, 800 s−1, 1500 s−1, 2500 s−1). EBSD analysis reveals a non-linear increase in global GND density with the strain rate rising, and a similar trend is also observed for local GND densities near the grain boundaries and that in the grain interiors. Furthermore, GND density decreases from the grain boundaries towards the grain interiors and this decline slows down at high strain rates. The origin of these trends is revealed by the connections between the GND characteristics and the behaviors of relevant microstructural components. The increase in grain boundary misorientations at higher strain rates promotes the increase of GND density near the grain boundaries. The denser distribution of dislocation cells, observed previously at high strain rates, is presumed to increase the GND density in the grain interiors and may also contribute to the slower decline in GND density near the grain boundaries. Additionally, grain refinement by higher strain rates also promotes the increase in total GND density. Further, the non-linear variation with respect to the strain rate, as well as the saturation at high strain rates, for grain boundary misorientations and grain sizes align well with the non-linear trend of GND density, consolidating the intimate connections between the characteristics of GNDs and the behaviors of these microstructure components. Full article
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18 pages, 4404 KiB  
Article
Analysis of Genetic Diversity and Population Structure of Endemic Endangered Goose (Anser cygnoides) Breeds Based on Mitochondrial CYTB
by Shangzong Qi, Suyu Fan, Haoyu Li, Yufan He, Yang Zhang, Wenming Zhao, Qi Xu and Guohong Chen
Animals 2024, 14(10), 1480; https://doi.org/10.3390/ani14101480 (registering DOI) - 16 May 2024
Abstract
The analysis of the genetic diversity and historical dynamics of endemic endangered goose breeds structure has attracted great interest. Although various aspects of the goose breed structure have been elucidated, there is still insufficient research on the genetic basis of endemic endangered Chinese [...] Read more.
The analysis of the genetic diversity and historical dynamics of endemic endangered goose breeds structure has attracted great interest. Although various aspects of the goose breed structure have been elucidated, there is still insufficient research on the genetic basis of endemic endangered Chinese goose breeds. In this study, we collected blood samples from Lingxiang White (LX), Yan (YE), Yangjiang (YJ), Wuzong (WZ), Xupu (XP), and Baizi (BZ) geese (Anser cygnoides) and used Sanger sequencing to determine the partial sequence of the cytochrome b (CYTB) gene in a total of 180 geese. A total of 117 polymorphic sites were detected in the 707 bp sequence of the mtDNA CYTB gene after shearing and correction, accounting for approximately 16.55% of the entire sequence. The AT content (51.03%) of the processed sequence was slightly higher than the GC content (48.97%), indicating a preference for purine bases. The YJ, YE, and WZ breeds had the highest population genetic diversity, with a haplotype diversity greater than 0.9 (Hd > 0.9) and average population nucleotide difference of 8.01 (K > 8.01). A total of 81 haplotypes were detected and divided into six major branches. Among the six goose breeds, there were frequent genetic exchanges among LX, YJ, YE, and WZ geese (Nm > 15.00). We analyzed the distribution of base-mismatch differences in goose breeds and tested their historical dynamics for neutrality in Tajima’s D and Fu’s Fs. For YJ and WZ geese, Tajima’s D > 0, but the difference was not significant (p > 0.05). The actual values for the two breeds exhibited multimodal Poisson distributions. The population patterns of the WZ and YJ geese are purportedly relatively stable, and the breeds have not experienced population expansions or bottleneck effects, which is consistent with the neutrality test results. This study provides new insights into the diverse genetic origins and historical dynamics that sustain endemic endangered goose breeds. Full article
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12 pages, 703 KiB  
Article
The Relationship and Effects of Self-Esteem and Body Shape on Eating Disorder Behavior: A Cross-Sectional Survey of Chinese University Students
by Zeng Gao, Jingyi Zhao, Sanying Peng and Han Yuan
Healthcare 2024, 12(10), 1034; https://doi.org/10.3390/healthcare12101034 (registering DOI) - 16 May 2024
Abstract
Background: Eating disorders (EDs) have become a global public health concern among adolescents and young adults. However, Chinese university students exhibit a high prevalence of eating disorders. This study aims to investigate the effects of self-esteem (SE) and body shape (BS) on ED [...] Read more.
Background: Eating disorders (EDs) have become a global public health concern among adolescents and young adults. However, Chinese university students exhibit a high prevalence of eating disorders. This study aims to investigate the effects of self-esteem (SE) and body shape (BS) on ED behaviors among Chinese university students. Methods: Using random sampling, 946 Chinese university students (aged 18 to 24, M = 19.94, SD = 1.04) participated in a survey comprising the Sick, Control, One, Fat, and Food Questionnaire (SCOFF-Q), the Body Shape Questionnaire (BS-Q), and the Rosenberg Self-Esteem Scale (RS-S) to assess their eating disorder or non-eating disorder (NED) behavior. Results: There was a significant positive correlation between body shape and eating disorder behaviors (r = 0.19, p < 0.01), while there was a significant negative correlation between self-esteem and eating disorder behaviors (r = −0.14, p = 0.001 < 0.01). Gender was a moderating factor in the relationship between body shape and eating disorder behaviors (t = 3.14, p = 0.002 < 0.01), while parents’ marital status was a moderating factor in the relationship between self-esteem and eating disorder behavior (t = 2.72, p = 0.007 < 0.01). Body shape (z = 6.47, p = 0.001 < 0.01), self-esteem (z = −2.81, p = 0.005 < 0.05), and gender (z = 3.06, p = 0.002 < 0.01) significantly influenced eating disorder behavior among Chinese university students aged 18–24 years. Conclusions: There was a direct effect between body shape and self-esteem and eating disorder behaviors among Chinese university students aged 18–24 years. Alarmingly, female university students are becoming susceptible to external influences on self-esteem and body shape, leading to eating disorder behaviors at an increasingly younger age in China. Full article
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13 pages, 4092 KiB  
Article
Photoperiod-Dependent Nutrient Accumulation in Rice Cultivated in Plant Factories: A Comparative Metabolomic Analysis
by Jingyao Yu, Yu Yang, Lanjun Luo, Fang Feng, Sana Saeed, Jie Luo, Chuanying Fang, Junjie Zhou and Kang Li
Foods 2024, 13(10), 1544; https://doi.org/10.3390/foods13101544 - 16 May 2024
Abstract
Plant factories offer a promising solution to some of the challenges facing traditional agriculture, allowing for year-round rapid production of plant-derived foods. However, the effects of conditions in plant factories on metabolic nutrients remain to be explored. In this study, we used three [...] Read more.
Plant factories offer a promising solution to some of the challenges facing traditional agriculture, allowing for year-round rapid production of plant-derived foods. However, the effects of conditions in plant factories on metabolic nutrients remain to be explored. In this study, we used three rice accessions (KongYu131, HuangHuaZhan, and Kam Sweet Rice) as objectives, which were planted in a plant factory with strict photoperiods that are long-day (12 h light/12 h dark) or short-day (8 h light/16 h dark). A total of 438 metabolites were detected in the harvested rice grains. The difference in photoperiod leads to a different accumulation of metabolites in rice grains. Most metabolites accumulated significantly higher levels under the short-day condition than the long-day condition. Differentially accumulated metabolites were enriched in the amino acids and vitamin B6 pathway. Asparagine, pyridoxamine, and pyridoxine are key metabolites that accumulate at higher levels in rice grains harvested from the short-day photoperiod. This study reveals the photoperiod-dependent metabolomic differences in rice cultivated in plant factories, especially the metabolic profiling of taste- and nutrition-related compounds. Full article
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38 pages, 8003 KiB  
Review
A Review of Recent Developments in Biopolymer Nano-Based Drug Delivery Systems with Antioxidative Properties: Insights into the Last Five Years
by Magdalena Stevanović and Nenad Filipović
Pharmaceutics 2024, 16(5), 670; https://doi.org/10.3390/pharmaceutics16050670 (registering DOI) - 16 May 2024
Abstract
In recent years, biopolymer-based nano-drug delivery systems with antioxidative properties have gained significant attention in the field of pharmaceutical research. These systems offer promising strategies for targeted and controlled drug delivery while also providing antioxidant effects that can mitigate oxidative stress-related diseases. Generally, [...] Read more.
In recent years, biopolymer-based nano-drug delivery systems with antioxidative properties have gained significant attention in the field of pharmaceutical research. These systems offer promising strategies for targeted and controlled drug delivery while also providing antioxidant effects that can mitigate oxidative stress-related diseases. Generally, the healthcare landscape is constantly evolving, necessitating the continual development of innovative therapeutic approaches and drug delivery systems (DDSs). DDSs play a pivotal role in enhancing treatment efficacy, minimizing adverse effects, and optimizing patient compliance. Among these, nanotechnology-driven delivery approaches have garnered significant attention due to their unique properties, such as improved solubility, controlled release, and targeted delivery. Nanomaterials, including nanoparticles, nanocapsules, nanotubes, etc., offer versatile platforms for drug delivery and tissue engineering applications. Additionally, biopolymer-based DDSs hold immense promise, leveraging natural or synthetic biopolymers to encapsulate drugs and enable targeted and controlled release. These systems offer numerous advantages, including biocompatibility, biodegradability, and low immunogenicity. The utilization of polysaccharides, polynucleotides, proteins, and polyesters as biopolymer matrices further enhances the versatility and applicability of DDSs. Moreover, substances with antioxidative properties have emerged as key players in combating oxidative stress-related diseases, offering protection against cellular damage and chronic illnesses. The development of biopolymer-based nanoformulations with antioxidative properties represents a burgeoning research area, with a substantial increase in publications in recent years. This review provides a comprehensive overview of the recent developments within this area over the past five years. It discusses various biopolymer materials, fabrication techniques, stabilizers, factors influencing degradation, and drug release. Additionally, it highlights emerging trends, challenges, and prospects in this rapidly evolving field. Full article
(This article belongs to the Special Issue Biopolymers for Biomedical and Pharmaceutical Applications)
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19 pages, 3772 KiB  
Article
Plasma Proteins Associated with COVID-19 Severity in Puerto Rico
by Lester J. Rosario-Rodríguez, Yadira M. Cantres-Rosario, Kelvin Carrasquillo-Carrión, Alexandra Rosa-Díaz, Ana E. Rodríguez-De Jesús, Verónica Rivera-Nieves, Eduardo L. Tosado-Rodríguez, Loyda B. Méndez, Abiel Roche-Lima, Jorge Bertrán and Loyda M. Meléndez
Int. J. Mol. Sci. 2024, 25(10), 5426; https://doi.org/10.3390/ijms25105426 (registering DOI) - 16 May 2024
Abstract
Viral strains, age, and host factors are associated with variable immune responses against SARS-CoV-2 and disease severity. Puerto Ricans have a genetic mixture of races: European, African, and Native American. We hypothesized that unique host proteins/pathways are associated with COVID-19 disease severity in [...] Read more.
Viral strains, age, and host factors are associated with variable immune responses against SARS-CoV-2 and disease severity. Puerto Ricans have a genetic mixture of races: European, African, and Native American. We hypothesized that unique host proteins/pathways are associated with COVID-19 disease severity in Puerto Rico. Following IRB approval, a total of 95 unvaccinated men and women aged 21–71 years old were recruited in Puerto Rico from 2020–2021. Plasma samples were collected from COVID-19-positive subjects (n = 39) and COVID-19-negative individuals (n = 56) during acute disease. COVID-19-positive individuals were stratified based on symptomatology as follows: mild (n = 18), moderate (n = 13), and severe (n = 8). Quantitative proteomics was performed in plasma samples using tandem mass tag (TMT) labeling. Labeled peptides were subjected to LC/MS/MS and analyzed by Proteome Discoverer (version 2.5), Limma software (version 3.41.15), and Ingenuity Pathways Analysis (IPA, version 22.0.2). Cytokines were quantified using a human cytokine array. Proteomics analyses of severely affected COVID-19-positive individuals revealed 58 differentially expressed proteins. Cadherin-13, which participates in synaptogenesis, was downregulated in severe patients and validated by ELISA. Cytokine immunoassay showed that TNF-α levels decreased with disease severity. This study uncovers potential host predictors of COVID-19 severity and new avenues for treatment in Puerto Ricans. Full article
(This article belongs to the Special Issue Molecular Research and Insights into COVID-19)
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18 pages, 1917 KiB  
Article
Policy Instrument Preferences and Optimization Strategies: Based Text Analysis of Provincial-Level Education Digitalization Policy from China
by Jing Cao, Chunmei Yu and Yan Wu
Educ. Sci. 2024, 14(5), 539; https://doi.org/10.3390/educsci14050539 (registering DOI) - 16 May 2024
Abstract
In the context of world education digitalization, the Chinese government has formulated China’s education digitalization strategy. The education digitalization policy tools of provincial governments are an important factor affecting the effectiveness of education digitalization policies. In this study, a text quantification and content [...] Read more.
In the context of world education digitalization, the Chinese government has formulated China’s education digitalization strategy. The education digitalization policy tools of provincial governments are an important factor affecting the effectiveness of education digitalization policies. In this study, a text quantification and content analysis is conducted on educational digital policy documents released by eight provinces of China during the 14th Five-Year Plan period in China. This is based on a two-dimensional analysis framework of “instruments-value” using instrument types and policy principles, and NVivo software. The research outcomes reveal the following: (1) The distribution of educational digital policy instrument types is uneven, with an excess of supply-side instruments and a noticeable shortage of demand-side instruments. (2) Different policy instruments exhibit varying degrees of preference in implementing policy principles. There is a stronger emphasis on technology application and balanced development, while the emphasis on service principles promoting diverse participation is relatively weaker. (3) The policy instruments that facilitate interaction between policymakers and educational entities require further strengthening. In light of these findings, local governments in China should strengthen the use of demand-side policy instruments to achieve comprehensiveness and sustainability in educational digitalization. Policymakers should pay more attention to the demands of educational entities to shift educational digitalization from being technology driven to being demand driven. Furthermore, policy instrument selection should adhere to the value of serving and supporting individuals and reinforce the concept of multi-participation in their development, ultimately improving the precision and coordination of policies, and achieving a harmonious integration of technological and value aspects of policy instruments. Full article
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19 pages, 302 KiB  
Article
New Uses of q-Generalized Janowski Function in q-Bounded Turning Functions
by Timilehin Gideon Shaba, Ferdous M. O. Tawfiq, Daniel Breaz and Luminit̨a-Ioana Cotiîrlă
Mathematics 2024, 12(10), 1552; https://doi.org/10.3390/math12101552 (registering DOI) - 16 May 2024
Abstract
In this paper, we discussed a new subclass JQ,AB(q) of bi-univalent functions in the unit disk U using q-generalized Janowski function and q-derivative. Additionally, certain properties were examined and effectively demonstrated, such as [...] Read more.
In this paper, we discussed a new subclass JQ,AB(q) of bi-univalent functions in the unit disk U using q-generalized Janowski function and q-derivative. Additionally, certain properties were examined and effectively demonstrated, such as the second Hankel determinant, Fekete–Szegö estimates, and Coefficients Bounds. Each of these bounds were precise and were confirmed by finding the extremal function for the new class. Furthermore, there are in-depth conversations available regarding certain intriguing specific cases of the outcomes achieved. Full article

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