As an important part of the boundary conditions on both sides of the high-speed railway track–bridge system, the seismic response of the subgrade structure is different from that of the bridge structure. This difference has become increasingly significant with the widespread adoption of continuous welded rail technology in bridge construction. Therefore, investigating the seismic response of the bridge system, with a specific focus on the longitudinal constraint effects of the subsequent subgrade track structure, is of paramount importance. Utilizing finite element software, two distinct bridge models are developed: one incorporating the subsequent subgrade track structure and another excluding it. Through nonlinear time history analysis under varying seismic intensities, it is demonstrated that the longitudinal constraint of the subsequent subgrade track structure mitigates the longitudinal displacements and internal forces in critical components of the high-speed railway track–bridge system. Concurrently, acknowledging the heightened complexity and cost associated with post-earthquake repairs of the bridge structure compared to subgrade structure, this study uses a risk transfer connecting beam device. This device can redirect seismic damage from bridge structure to subgrade structure, thereby potentially reducing post-seismic repair expenses for the bridge. Full article

Scaffold-guided breast tissue regeneration (SGBTR) can transform both reconstructive and cosmetic breast surgery. Implant-based surgery is the most common method. However, there are inherent limitations, as it involves replacement of tissue rather than regeneration. Regenerating autologous soft tissue has the potential to provide a more like-for-like reconstruction with minimal morbidity. Our SGBTR approach regenerates soft tissue by implanting additively manufactured bioresorbable scaffolds filled with autologous fat graft. A pre-clinical large animal study was conducted by implanting 100 mL breast scaffolds (n = 55) made from medical-grade polycaprolactone into 11 minipigs for 12 months. Various treatment groups were investigated where immediate or delayed autologous fat graft, as well as platelet rich plasma, were added to the scaffolds. Computed tomography and magnetic resonance imaging were performed on explanted scaffolds to determine the volume and distribution of the regenerated tissue. Histological analysis was performed to confirm the tissue type. At 12 months, we were able to regenerate and sustain a mean soft tissue volume of 60.9 ± 4.5 mL (95% CI) across all treatment groups. There was no evidence of capsule formation. There were no immediate or long-term post-operative complications. In conclusion, we were able to regenerate clinically relevant soft tissue volumes utilizing SGBTR in a pre-clinical large animal model. Full article

Background: Apolipoprotein E (APOE) gene polymorphism has been implicated in the pathogenesis of various metabolic disorders, including type 2 diabetes mellitus (T2DM). Type 2 diabetes mellitus (T2DM) is a major public health concern worldwide, including in Pakistan. Cardiovascular problems linked with T2DM have a significant impact on individuals and society. The goal of this study is to investigate the relationship between Apolipoprotein E (ApoE) genotypes, dyslipidemia, and cardiovascular complications such as ischemic heart disease (IHD) and stroke. Methods: This study was carried out on 260 subjects divided into controls and diabetics. The diabetics were further divided into four subgroups such as D1: diabetics without cardiovascular issues, D2: diabetics with heart disease, D3: diabetics with stroke, and D4: diabetics with both heart disease and stroke. Anthropometric parameters (age, BMI) and risk factors (smoking, diabetes duration, hypertension) were assessed in all groups. Serum levels of TC, TG, LDL, HDL, VLDL, creatinine, BSF, and HbA1c were also measured. Apolipoprotein E gene polymorphism was determined using PCR-RFLP. Results: Hypertension, BMI, and dyslipidemia are defined as elevated levels of total cholesterol, triglycerides, LDL, and VLDL, and decreased levels of HDL. Uncontrolled hyperglycemia (elevated fasting blood sugar and glycated hemoglobin) in T2DM was linked to vascular complications such as IHD and stroke. Hypertension was prevalent in 79.3% of the population. Stage 2 hypertension was more prevalent in all age groups. It was also noted that common genotypes in the Pakistani population are 3/3, 4/4, 2/3, and 3/4. The frequency of genotypes 3/4 and 2/3 is highest in diabetics with stroke. Genotype 3/3 is present frequently in diabetics with IHD/stroke and patients with both these complications. However, genotype 4/4 is most frequently found in diabetics with IHD. Conclusions: It is concluded that BMI, hypertension, hyperglycemia, atherosclerosis, and dyslipidemia are linked with cardiovascular complications of type 2 diabetes. Apolipoprotein E gene polymorphism is associated with cardiovascular disease in patients with diabetes by affecting the lipid profile. Full article

The efficacy of selenium-chelating polypeptides derived from wheat protein hydrolysate (WPH-Se) includes enhancing antioxidant capacity, increasing bioavailability, promoting nutrient absorption, and improving overall health. This study aimed to enhance the bioavailability and functional benefits of exogenous selenium by chelating with wheat gluten protein peptides, thereby creating bioactive peptides with potentially higher antioxidant capabilities. In this study, WPH-Se was prepared with wheat peptide and selenium at a mass ratio of 2:1, under a reaction system at pH 8.0 and 80 °C. The in vitro antioxidant activity of WPH-Se was evaluated by determining the DPPH, OH, and ABTS radical scavenging rate and reducing capacity under different conditions, and the composition of free amino acids and bioavailability were also investigated at various digestion stages. The results showed that WPH-Se possessed significant antioxidant activities under different conditions, and DPPH, OH, and ABTS radical scavenging rates and reducing capacity remained high at different temperatures and pH values. During gastrointestinal digestion in vitro, both the individual digestate and the final digestate maintained high DPPH, OH, and ABTS radical scavenging rates and reducing capacity, indicating that WPH-Se was able to withstand gastrointestinal digestion and exert antioxidant effects. Post-digestion, there was a marked elevation in tryptophan, cysteine, and essential amino acids, along with the maintenance of high selenium content in the gastrointestinal tract. These findings indicate that WPH-Se, with its enhanced selenium and amino acid profile, serves as a promising ingredient for dietary selenium and antioxidant supplementation, potentially enhancing the nutritional value and functional benefits of wheat gluten peptides. Full article

This paper introduces a recently restored late-medieval tower house called the Dobbins, located in the historic town of Carrickfergus, Northern Ireland. The restoration process transformed what appeared visually as a Georgian house into a medieval-esque tower house. Despite considerable historical and archaeological research prior to the restoration, the responses from the local community were mixed. This ignited a discussion surrounding whether or not the Dobbins is authentic. Multiple understandings of authenticity are used to analyse the restoration results and evaluate whether a desire for authenticity can be detected. It is clear that authenticity is a myriad of complexities and contradictions comprising tangible, intangible, stable and dynamic elements, and when this is a motivation for restoration the complexity is embedded in the result. This is deconstructed to find that tourism and local identities underpinned the motivation for authenticity and their role in influencing the hierarchy of narratives retold through the restored Dobbins will be discussed. By exploring the authenticity craze through the prism of the Dobbins, this paper allows a deeper understanding of the term to be generated. Full article

Vanadium compounds are known to exert insulin-enhancing activity, normalize elevated blood glucose levels in diabetic subjects, and show significant activity in models of insulin resistance (IR). Faced with insulin resistance, the present work investigates the antidiabetic performance of a known oxidovanadium(IV)-based coordination compound—[V^IVO(octd)]—and effects associated with glucocorticoid-induced insulin resistance in mice. The effects of [V^IVO(octd)] were evaluated in a female Swiss mice model of insulin resistance induced by seven days of dexamethasone treatment in comparison with groups receiving metformin treatment. Biological assays such as hematological, TyG index, hepatic lipids, glycogen, oxidative stress in the liver, and oral glucose tolerance tests were evaluated. [V^IVO(octd)] was characterized with ⁵¹V NMR, infrared spectroscopy (FTIR), electron paramagnetic resonance (EPR), electronic absorption spectroscopy, and mass spectrometry (ESI–FT–MS). The [V^IVO(octd)] oral treatment (50 mg/kg) had an antioxidant effect, reducing 50% of fast blood glucose (p < 0.05) and 25% of the TyG index, which is used to estimate insulin resistance (p < 0.05), compared with the non-treated group. The oxidovanadium–sulfur compound is a promising antihyperglycemic therapeutic, including in cases aggravated by insulin resistance induced by glucocorticoid treatment. Full article

This pioneering study aimed to evaluate the cryopreservation of semen from P. falkneri (n = 4) and P. motoro (n = 4), maintained ex situ at the Sao Paulo Aquarium, Brazil. For this purpose, the animals were physically restrained, biometric data of the disc and clasper were obtained, and semen was collected through manual massage. Total motility and progressive motility parameters were evaluated using Computer-Assisted Sperm Analysis (CASA) with IVOS II equipment and Animal Breeders II software. The semen extenders INRA 96 and OptiXcell were used to assess their efficacy in sperm cryopreservation. INRA required the addition of 5% dimethyl sulfoxide (DMSO) as a cryoprotectant. The results indicated that there was no difference in semen motility values before and after freezing with INRA + DMSO (p = 0.6226). On the other hand, samples cryopreserved with OptiXcell showed a difference in semen motility post-thaw (p = 0.0156). These findings contribute to a broader study on optimizing cryopreservation protocols to ensure long-term viability and fertility of semen, enhancing genetic diversity and supporting wild population restoration. A multidisciplinary approach integrating reproductive biology, ecology, physiology, and assisted reproduction technologies, aligned with the One Conservation concept, is essential for advancing conservation and management strategies for these threatened species. Full article

Aluminum (Al) toxicity in acidic soils can significantly reduce peanut yield. The physiological response of peanut leaves to Al poisoning stress still has not been fully explored. This research examined the influences of Al toxicity on peanut leaves by observing the leaf phenotype, scanning the leaf area and perimeter, and by measuring photosynthetic pigment content, physiological response indices, leaf hormone levels, and mineral element accumulation. Fluorescence quantitative RT–PCR (qPCR) was utilized to determine the relative transcript level of specific genes. The results indicated that Al toxicity hindered peanut leaf development, reducing their biomass, surface area, and perimeter, although the decrease in photosynthetic pigment content was minimal. Al toxicity notably affected the activity of antioxidative enzymes, proline content, and MDA (malondialdehyde) levels in the leaves. Additionally, Al poisoning resulted in the increased accumulation of iron (Fe), potassium (K), and Al in peanut leaves but reduced the levels of calcium (Ca), manganese (Mn), copper (Cu), zinc (Zn), and magnesium (Mg). There were significant changes in the content of hormones and the expression level of genes connected with hormones in peanut leaves. High Al concentrations may activate cellular defense mechanisms, enhancing antioxidative activity to mitigate excess reactive oxygen species (ROS) and affecting hormone-related gene expression, which may impede leaf biomass and development. This research aimed to elucidate the physiological response mechanisms of peanut leaves to Al poisoning stress, providing insights for breeding new varieties resistant to Al poisoning. Full article

The present study reports on the preparation of a cellulose fiber (CF) composite from D. lutescens, combined with copper oxide nanoparticles (DL@CF/CuO), to prolong the shelf life of tomatoes after harvest. The isolated cellulose fiber material was comprehensively characterized using XRD, FTIR, and FE-SEM analyses. The DLCF and DL@CF/CuO nanoparticles exhibited crystalline cellulose, as indicated by the XRD investigation. Both DLCF and DL@CF/CuO showed O-H and C-H FTIR spectra with identifiable vibrational peaks. The FE-SEM images depicted the dispersion of DL@CF/CuO-based fibers in a cellulose fiber matrix containing CuO nanoparticles. A 0.3% (wt/wt), a solution of DL@CF/CuO was coated onto the surface of early ripening tomato fruits. After a 25-day storage period at 25–29 °C and 85% RH, the results showed a significant extension in the shelf life of the tomato fruits, in line with changes in physiological properties and fruit quality. The extension of shelf life in tomato fruit epidermis treated with DL@CF/CuO was confirmed through FE-SEM analysis. L929 fibroblast cells were treated with the developed DL@CF/CuO nanocomposite, and no signs of toxicity were detected up to 75 µg/mL. Additionally, the DL@CF/CuO nanocomposite exhibited significant antifungal activity against Aspergillus flavus. In conclusion, this study provides novel insights for sustainable food security and waste control in the agricultural and food industries. Full article

Carbon Dioxide-Enhanced Coalbed Methane (CO₂-ECBM), a progressive technique for extracting coalbed methane, substantially boosts gas recovery and simultaneously reduces greenhouse gas emissions. In this process, the dynamics of coalbed fractures, crucial for CO₂ and methane migration, significantly affect carbon storage and methane retrieval. However, the extent to which fracture roughness, under the coupled thermal-hydro-mechanic effects, impacts engineering efficiency remains ambiguous. Addressing this, our study introduces a pioneering, cross-disciplinary mathematical model. This model innovatively quantifies fracture roughness, incorporating it with gas flow dynamics under multifaceted field conditions in coalbeds. This comprehensive approach examines the synergistic impact of CO₂ and methane adsorption/desorption, their pressure changes, adsorption-induced coalbed stress, ambient stress, temperature variations, deformation, and fracture roughness. Finite element analysis of the model demonstrates its alignment with real-world data, precisely depicting fracture roughness in coalbed networks. The application of finite element analysis to the proposed mathematical model reveals that (1) fracture roughness ξ markedly influences residual coalbed methane and injected CO₂ pressures; (2) coalbed permeability and porosity are inversely proportional to ξ; and (3) adsorption/desorption reactions are highly sensitive to ξ. This research offers novel insights into fracture behavior quantification in coalbed methane extraction engineering. Full article

The electro-thermal performance of silicon nanosheet field-effect transistors (NSFETs) with various parasitic bottom transistor (tr_pbt)-controlling schemes is evaluated. Conventional punch-through stopper, trench inner-spacer (TIS), and bottom oxide (BOX) schemes were investigated from single-device to circuit-level evaluations to avoid overestimating heat’s impact on performance. For single-device evaluations, the TIS scheme maintains the device temperature 59.6 and 50.4 K lower than the BOX scheme for n/pFETs, respectively, due to the low thermal conductivity of BOX. However, when the over-etched S/D recess depth (T_SD) exceeds 2 nm in the TIS scheme, the RC delay becomes larger than that of the BOX scheme due to increased gate capacitance (C_gg) as the T_SD increases. A higher TIS height prevents the C_gg increase and exhibits the best electro-thermal performance at single-device operation. Circuit-level evaluations are conducted with ring oscillators using 3D mixed-mode simulation. Although TIS and BOX schemes have similar oscillation frequencies, the TIS scheme has a slightly lower device temperature. This thermal superiority of the TIS scheme becomes more pronounced as the load capacitance (C_L) increases. As C_L increases from 1 to 10 fF, the temperature difference between TIS and BOX schemes widens from 1.5 to 4.8 K. Therefore, the TIS scheme is most suitable for controlling tr_pbt and improving electro-thermal performance in sub-3 nm node NSFETs. Full article

To study the variation laws and effects of asphalt mastic under the cooperative interaction of different temperatures and humidities, cyclic conditions for different temperature ranges were set to conduct indoor experimental simulations of thermal–humidity coupling cycles. Firstly, the macroscopic performance changes in styrene butadiene styrene polymer (SBS)-modified asphalt mastic were evaluated by the penetration test, softening point test, ductility test, Brookfield rotational viscosity test, and double-edge notched tensile (DENT) test; then, the mechanism of performance changes was explored from the perspective of chemical composition by combining this with Fourier transform infrared spectroscopy (FTIR). The research results show that with the increase in thermal–humidity coupling cycles, SBS-modified asphalt mastic exhibited aging phenomena such as hardening and embrittlement, and its macroscopic performance deteriorated; under the same test conditions, the interval with a higher temperature difference had a greater impact on the performance of the mastic; the sulfoxide index (IS-O) of SBS-modified asphalt mastic increases after thermal–humidity coupling cycles, while the isoprene index (IB) decreases. Full article

We present the first comprehensive review of 62 migratory shorebird species in Mongolia, covering their ecological status, IUCN assessments at regional or national levels, population trends, threats, and conservation measures. Mongolia hosts a total of 62 shorebird species from twenty-two genera and seven families, with six species classified as globally threatened: the Critically Endangered Sociable Lapwing, the Endangered Siberian Sandplover, the Far Eastern Curlew, the Great Knot, and the Vulnerable Sharp-Tailed Sandpiper. Both national and global IUCN Red List assessments highlight Mongolia’s significance as a breeding and passage migrating site for globally threatened and Near-Threatened shorebirds. Species richness is higher in northern regions compared to the south, with the highest diversity found in areas with complex aquatic ecosystems. Global population trends indicate a decline in 61% of species, with 18% remaining stable, 16% of unknown status, and 5% increasing. At the national level, most species are stable (61%), 34% status is unknown, and 5% are decreasing. Anthropogenic-induced threats, including habitat loss and degradation, pollution, disturbance, and harvesting, pose significant risks to 69% of species, while natural disasters affect 11%. Additionally, 8% of species are impacted by accidental mortality and intrinsic factors, and 5% by changes in native species. Despite these threats, no specific conservation action plans exist for shorebirds in Mongolia. However, general conservation measures are in place, such as environmental and fauna protection laws, regulations on foreign trade in endangered species, and the establishment of protected areas under governmental resolutions. Mongolia also participates in international conventions like the Convention on Biological Diversity (CBD), Ramsar, and Migratory Species (CMS), and has developed national red lists, red books, and publications such as A Summary Conservation Action Plan for Mongolian Birds, Important Bird Areas to support conservation efforts. Full article

This paper presents an in-depth exploration of the application of Artificial Intelligence (AI) in enhancing the resilience of microgrids. It begins with an overview of the impact of natural events on power systems and provides data and insights related to power outages and blackouts caused by natural events in Estonia, setting the context for the need for resilient power systems. Then, the paper delves into the concept of resilience and the role of microgrids in maintaining power stability. The paper reviews various AI techniques and methods, and their application in power systems and microgrids. It further investigates how AI can be leveraged to improve the resilience of microgrids, particularly during different phases of an event occurrence time (pre-event, during event, and post-event). A comparative analysis of the performance of various AI models is presented, highlighting their ability to maintain stability and ensure a reliable power supply. This comprehensive review contributes significantly to the existing body of knowledge and sets the stage for future research in this field. The paper concludes with a discussion of future work and directions, emphasizing the potential of AI in revolutionizing power system monitoring and control. Full article

Fungi play an important and multifaceted role in the production and processing of food, influencing various stages from cultivation to consumption. This paper explores the complex relationship between fungi and food systems, highlighting their diverse contributions. Firstly, fungi serve as essential agents in food cultivation, aiding in the breakdown of organic matter and the recycling of nutrients, and promoting plant growth through symbiotic relationships. Moreover, fungi such as yeasts and molds are integral to fermentation processes, yielding a wide array of fermented foods and beverages with unique flavors and textures. Additionally, fungi are indispensable in the creation of enzymes and bioactive compounds utilized in food processing, enhancing the nutritional value, shelf life, and safety. However, certain fungal species pose significant challenges as food spoilage agents and mycotoxin producers, necessitating stringent quality control measures. Understanding the intricate interplay between fungi and food systems is essential for optimizing food production, ensuring food security, and mitigating the risks associated with fungal contamination. This paper synthesizes current research to elucidate the important role that fungus play in shaping the modern food industry and underscores the importance of ongoing scientific inquiry in harnessing their potential for sustainable and safe food production. Full article

Mercury (Hg) analyses in species of fish are performed for two reasons: (1) to safeguard human health; and (2) to assess environmental quality, since different environmental changes may increase the Hg concentrations in fish. These analyses are important since both natural and human activities can increase these Hg concentrations, which can vary extensively, depending on the species, age and catching location. Hg-contaminated fish or other marine foodstuffs can be only detected by chemical analysis. If the aim of Hg analysis is to protect the health of marine food consumers, researcher workers must consider the location where the fish were caught and interpret the results accordingly. Health and environmental officials must appreciate that in specific places, local people may have a daily diet consisting entirely of fish or other marine foods, and these individuals should not be exposed to high concentrations of Hg. Regional and national health and environmental officials should follow the recent guidance of international organizations when drawing their final conclusions about whether the products are safe or unsafe to eat. Correct statistical calculations are not always carried out; so, too high Hg amounts could be presented, and fish eaters could be protected. This work has been conducted to show the differences in Hg concentrations between weighted (weighted with fish weights) and arithmetic means. Thus, the mean that is only weighted also includes the Hg content in fishes; so, the exposure to Hg can be evaluated. Full article

UV-B is an important environmental factor that differentially affects plant growth and secondary metabolites. The effects of supplemental ultraviolet-B (sUV-B) exposure (T1, 1.40 kJ·m⁻²·day⁻¹; T2, 2.81 kJ·m⁻²·day⁻¹; and T3, 5.62 kJ·m⁻²·day⁻¹) on the growth biomass, physiological characteristics, and secondary metabolites were studied. Our results indicated that leaf thickness was significantly (p < 0.05) reduced under T3 relative to the control (natural light exposure, CK); The contents of 6-BA and IAA were significantly reduced (p < 0.05); and the contents of ABA, 10-deacetylbaccatin III, and baccatin III were significantly (p < 0.05) increased under T1 and T2. The paclitaxel content was the highest (0.036 ± 0.0018 mg·g⁻¹) under T3. The cephalomannine content was significantly increased under T1. Hmgr gene expression was upregulated under T1 and T3. The gene expressions of Bapt and Dbtnbt were significantly (p < 0.05) upregulated under sUV-B exposure, and the gene expressions of CoA, Ts, and Dbat were significantly (p < 0.05) downregulated. A correlation analysis showed that the 6-BA content had a significantly (p < 0.05) positive correlation with Dbat gene expression. The IAA content had a significantly (p < 0.05) positive correlation with the gene expression of Hmgr, CoA, Ts, and Dbtnbt. The ABA content had a significantly (p < 0.05) positive correlation with Bapt gene expression. Dbat gene expression had a significantly (p < 0.05) positive correlation with the 10-deacetylbaccatin content. Hmgr gene expression was positively correlated with the contents of baccatin III and cephalomannine. Bapt gene expression had a significantly (p < 0.01) positive correlation with the paclitaxel content. A factor analysis showed that the accumulation of paclitaxel content was promoted under T2, which was helpful in clarifying the accumulation of taxane compounds after sUV-B exposure. Full article

A green economy is not a common economic practice. This leads the governments in many countries to focus on institutional arrangement and policy development. The institutional arrangement is one of the main significant factors, while green economy policies have to be well developed to support stakeholders and put less pressure on local communities. Hence, this research aims to understand green economic development in Cambodia by focusing on institutional arrangements and green economic development policies. Thus, this research’s priority was to evaluate their background and progress, and a comprehensive SWOT (strengths, weaknesses, opportunities, and threats) analysis was conducted based on their progress/transition. This research conducted background, progress, and SWOT analyses based on (i) the government’s documents, including the code, laws, royal decrees, sub-decrees, prakas, policies, strategic plans, roadmaps, and reports; (ii) development partners’ reports from reliable sources, such as UN agencies, UN Programs, ASEAN, the Asian Development Bank, and the World Bank; and (iii) existing literature. This research presented the results and discussed the findings encompassed by political and economic conditions, institutional arrangement and capacities, policy development and coordination, and participation of the public and stakeholders, as well as global green cooperation and funding, which were conditioned by the experiences from the COVID-19 pandemic and the uncertainties resulting from global geopolitical conflicts, such as the Russian–Ukrainian conflicts. Moreover, this research discussed weaknesses against strengths and threats against opportunities to suggest solutions or implications. Full article

Background: The use of magnification appears to offer advantages in dental preparation for fixed prosthetics and is widely employed in clinical practice, although it has not yet been thoroughly documented. Therefore, the primary objective is to determine the impact of magnification on the quality of finish lines during the performance of preparations for fixed prostheses. Methods: Sixty-four natural teeth were randomized into two groups: Group O (preparation without additional magnification) and Group L (preparation with Kitus^® 2.5× magnifying glasses). The teeth were prepared for full crowns, and the finish lines were evaluated under the OPMI^® PicoZeiss dental microscope at 10× magnification, based on the criteria of Continuity, Roughness, and Thickness. Results: There were no significant differences between the groups in any of the parameters evaluated. In Thickness, Group O had a median (IQR) of 600 µm (500; 800 µm) and Group L, 600 µm (400; 800 µm). Group L was Continuous in 64.8% of the cases, Slightly Continuous in 26.1% of the evaluations, and Not Continuous in 9.1% of the cases, thus having a slight advantage over Group O, whose values were 58.0%, 35.2%, and 6.8%, respectively. Group L was Polished in 71.0% of the cases and Rough in 29.0% of the evaluations, against 69.3% and 30.7% of Group O, respectively. These results were obtained using IBM SPSS ^® software, version 29.0. Conclusions: The 2.5× magnification magnifiers demonstrated a slight positive impact on improving the quality of dental preparations for fixed prostheses. Nevertheless, since the results are not statistically significant, it is difficult to extrapolate them to the broader population. Full article

This study explored the relationship between technology acceptance and learning satisfaction within a virtual learning environment (VLE) with cognitive presence, cognitive engagement, social presence, and emotional engagement as mediators. A total of 237 university students participated and completed a questionnaire after studying in the Virbela VLE. The results revealed direct and indirect links between technology acceptance and virtual learning satisfaction. The mediation analysis showed the critical mediating roles of cognitive presence and emotional engagement in fostering satisfaction. There also appeared to be a sequential mediating pathway from technology acceptance to learning satisfaction through social presence and emotional engagement. Notably, cognitive engagement and social presence did not have a significant mediating effect on satisfaction. These results provide a supplementary perspective on how technological, cognitive, and emotional factors can enhance student satisfaction in VLEs. The study concludes with several implications for future research and practice of VLEs in higher education. Full article

Gas–oil–water three-phase slug flows in pipes commonly exist in the oil and gas industry as oil fields are becoming mature and water production is becoming inevitable. Although studies on multiphase flows in pipes have been ongoing for decades, most previous research has focused on gas–liquid or oil–water two-phase flows, with limited studies on gas–liquid–liquid flows. This leads to limited modeling studies on gas–liquid–liquid flows. One factor contributing to the complexity of the gas–liquid–liquid flow is the mixing between the oil and water phases, which have closer fluid properties and low interfacial tension. Restrictions or piping components play a crucial role in altering phase mixing. Unfortunately, modeling studies that consider the effects of these restrictions are limited due to the scarcity of experimental research. To address this gap, we conducted experimental studies on a gas–liquid–liquid flow downstream of a restriction and developed a new mechanistic modeling approach to predict the pressure gradient. Our model focuses on the flow pattern where the oil and water phases are partially mixed. This work emphasizes the modeling approach. The model evaluation results show that the model outperforms other existing models, with an average absolute relative error of 6.71%. Additionally, the parametric study shows that the new modeling approach effectively captures the effects of restriction size, water cut, and gas and liquid flow rates on the three-phase slug flow pressure gradient in horizontal pipes. Most previous slug flow modeling work assumes either a stratified flow or fully dispersed flow between the oil and water phases. This work provides a novel perspective in modeling a three-phase slug flow in which the oil and water phases are partially mixed. In addition, this novel approach to modeling the restriction effects on the pressure gradient paves the way for future modeling for different types of piping components or restrictions. Full article