The 2023 MDPI Annual Report has
been released!
 
26 pages, 3604 KiB  
Article
Structure Design and Heat Transfer Performance Analysis of a Novel Composite Phase Change Active Cooling Channel Wall for Hypersonic Aircraft
by Weichen Li, Jieliang Zhao, Xiangbing Wu, Lulu Liang, Wenzhong Wang and Shaoze Yan
Micromachines 2024, 15(5), 623; https://doi.org/10.3390/mi15050623 (registering DOI) - 06 May 2024
Abstract
Efficient and stable heat dissipation structure is crucial for improving the convective heat transfer performance of thermal protection systems (TPSs) for hypersonic aircraft. However, the heat dissipation wall of the current TPS is limited by a single material and structure, inefficiently dissipating the [...] Read more.
Efficient and stable heat dissipation structure is crucial for improving the convective heat transfer performance of thermal protection systems (TPSs) for hypersonic aircraft. However, the heat dissipation wall of the current TPS is limited by a single material and structure, inefficiently dissipating the large amount of accumulated heat generated during the high-speed maneuvering flight of hypersonic aircraft. Here, a convection cooling channel structure of TPS is proposed, which is an innovative multi-level structure inspired by the natural honeycomb. An active cooling channel (PCM-HC) is designed by using a variable-density topology optimization method and filled with phase change material (PCM). Numerical simulations are used to investigate the thermal performance of the PCM-HC wall, focusing on the influence of PCM properties, structural geometric parameters, and PCM types on heat transfer characteristics. The results demonstrate that the honeycomb-like convection cooling channel wall, combined with PCM latent heat of phase change, exhibits superior heat dissipation capability. With a heat flux input of 50 kW/m2, the maximum temperature on the inner wall of PCM-HC is reduced by 12 K to 20 K. Different PCMs have opposing effects on heat transfer performance due to their distinct thermophysical properties. This work can provide a theoretical basis for the design of high-efficiency cooling channel, improving the heat dissipation performance in the TPS of hypersonic aircraft. Full article
(This article belongs to the Special Issue Heat Transfer and Fluid Flow in Microstructures)
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15 pages, 1064 KiB  
Article
Local-Global Representation Enhancement for Multi-View Graph Clustering
by Xingwang Zhao, Zhedong Hou and Jie Wang
Electronics 2024, 13(9), 1788; https://doi.org/10.3390/electronics13091788 (registering DOI) - 06 May 2024
Abstract
In recent years, multi-view graph clustering algorithms based on representations learning have received extensive attention. However, existing algorithms are still limited in two main aspects, first, most algorithms employ graph convolution networks to learn the local representations, but the presence of high-frequency noise [...] Read more.
In recent years, multi-view graph clustering algorithms based on representations learning have received extensive attention. However, existing algorithms are still limited in two main aspects, first, most algorithms employ graph convolution networks to learn the local representations, but the presence of high-frequency noise in these representations limits the clustering performance. Second, in the process of constructing a global representation based on the local representations, most algorithms focus on the consistency of each view while ignoring complementarity, resulting in lower representation quality. To address the aforementioned issues, a local-global representation enhancement for multi-view graph clustering algorithm is proposed in this paper. First, the low-frequency signals in the local representations are enhanced by a low-pass graph encoder, which yields smoother and more suitable local representations for clustering. Second, by introducing an attention mechanism, the local embedded representations of each view can be weighted and fused to obtain a global representation. Finally, to enhance the quality of the global representation, it is jointly optimized using the neighborhood contrastive loss and reconstruction loss. The final clustering results are obtained by applying the k-means algorithm to the global representation. A wealth of experiments have validated the effectiveness and robustness of the proposed algorithm. Full article
(This article belongs to the Special Issue Advances in Intelligent Data Analysis and Its Applications, Volume II)
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15 pages, 5325 KiB  
Article
A New Sustainable PPT Coating Based on Recycled PET to Improve the Durability of Hydraulic Concrete
by Adrián Bórquez-Mendivil, Carlos Paulino Barrios-Durstewitz, Rosa Elba Núñez-Jáquez, Abel Hurtado-Macías, Jesús Eduardo Leal-Pérez, Joaquín Flores-Valenzuela, Blanca Alicia García-Grajeda, Francisca Guadalupe Cabrera-Covarrubias, José Miguel Mendivil-Escalante and Jorge Luis Almaral-Sánchez
Polymers 2024, 16(9), 1297; https://doi.org/10.3390/polym16091297 (registering DOI) - 06 May 2024
Abstract
A new, sustainable polypropylene terephthalate (PPT) coating was synthesized from recycled polyethylene terephthalate (PET) and applied onto a hydraulic concrete substrate to improve its durability. For the first step, PET bottle wastes were ground and depolymerized by glycolysis using propylene glycol (PG) in [...] Read more.
A new, sustainable polypropylene terephthalate (PPT) coating was synthesized from recycled polyethylene terephthalate (PET) and applied onto a hydraulic concrete substrate to improve its durability. For the first step, PET bottle wastes were ground and depolymerized by glycolysis using propylene glycol (PG) in a vessel-type reactor (20–180 °C) to synthesize bis(2-hydroxypropyl)-terephthalate (BHPT), which was applied as a coating to one to three layers of hydraulic concrete substrate using the brushing technique and polymerized (150 °C for 15 h) to obtain PPT. PET, BHPT, and PPT were characterized by FT-IR, PET, and PPT using TGA, and the PPT coatings by SEM (thickness), ASTM-D3359-17 (adhesion), and water contact angle (wettability). The durability of hydraulic concrete coated with PPT was studied using resist chloride ion penetration (ASTM-C1202-17), carbonation depth at 28 days (RILEM-CPC-18), and the absorption water ratio (ASTM-C1585-20). The results demonstrated that the BHPT and PPT were synthetized (FT-IR), and PPT had a similar thermal behavior to PET (TGA); the PPT coatings had good adhesion to the substrate, with thicknesses of micrometric units. PPT coatings presented hydrophilic hydrophilic behavior like PET coatings, and the durability of hydraulic concrete coated with PPT (2–3 layers) improved (migration of chloride ions decreased, carbonation depth was negligible, and the absorption water ratio decreased). Full article
(This article belongs to the Section Polymer Composites and Nanocomposites)
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5 pages, 436 KiB  
Editorial
Cardiopulmonary Resuscitation: Clinical Updates and Perspectives
by Stephan Marsch and Timur Sellmann
J. Clin. Med. 2024, 13(9), 2717; https://doi.org/10.3390/jcm13092717 (registering DOI) - 06 May 2024
Abstract
Cardiopulmonary resuscitation (CPR) stands as a cornerstone in emergency care, representing the crucial link between life and death for victims of cardiac arrest [...] Full article
(This article belongs to the Special Issue Cardiopulmonary Resuscitation: Clinical Updates and Perspectives)
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12 pages, 280 KiB  
Article
Heroic Vulnerability and the Vietnamese Refugee Experience in Thi Bui’s The Best We Could Do
by María Porras Sánchez
Humanities 2024, 13(3), 71; https://doi.org/10.3390/h13030071 (registering DOI) - 06 May 2024
Abstract
Autographics illustrating refugee and migrant experiences are frequently published, proof of the power of comics to engage with representations of trauma and vulnerability. Thi Bui’s graphic memoir The Best We Could Do tells the story of the author and her family as “boat [...] Read more.
Autographics illustrating refugee and migrant experiences are frequently published, proof of the power of comics to engage with representations of trauma and vulnerability. Thi Bui’s graphic memoir The Best We Could Do tells the story of the author and her family as “boat people”, before and after migrating from Việt Nam to the US in the so-called second “wave” of refugees (1978–1980). If, as Judith Butler argues, vulnerable lives are more grievable when exposed and acknowledged, then self-representation of vulnerable lives might offer a site of resistance against precarity. Thi Bui’s graphic memoir is no exception, since she deals with common themes in Vietnamese American literature such as PTSD, inherited family trauma or everyday bordering, inscribing herself and her family in the counterhistory of the US regarding the Vietnam War, while also addressing themes and motifs recurrent in Asian American comics. The author follows a thematic concern present in Vietnamese American narratives, which tends to present the refugee experience from a heroic perspective, but this is limited and antagonised by Bui’s personal story, who feels estranged from her parents, their past in Việt Nam and the war. As this article shows, the recording and commemoration of her parents’ memories help her to identify with the family legacy of heroic vulnerability in her role as a mother. Full article
(This article belongs to the Special Issue Border Politics & Refugee Narratives in Contemporary Literature)
12 pages, 2954 KiB  
Article
Audio Recognition of the Percussion Sounds Generated by a 3D Auto-Drum Machine System via Machine Learning
by Spyros Brezas, Alexandros Skoulakis, Maximos Kaliakatsos-Papakostas, Antonis Sarantis-Karamesinis, Yannis Orphanos, Michael Tatarakis, Nektarios A. Papadogiannis, Makis Bakarezos, Evaggelos Kaselouris and Vasilis Dimitriou
Electronics 2024, 13(9), 1787; https://doi.org/10.3390/electronics13091787 (registering DOI) - 06 May 2024
Abstract
A novel 3D auto-drum machine system for the generation and recording of percussion sounds is developed and presented. The capabilities of the machine, along with a calibration, sound production, and collection protocol are demonstrated. The sounds are generated by a drumstick at pre-defined [...] Read more.
A novel 3D auto-drum machine system for the generation and recording of percussion sounds is developed and presented. The capabilities of the machine, along with a calibration, sound production, and collection protocol are demonstrated. The sounds are generated by a drumstick at pre-defined positions and by known impact forces from the programmable 3D auto-drum machine. The generated percussion sounds are accompanied by the spatial excitation coordinates and the correspondent impact forces, allowing for large databases to be built, which are required by machine learning models. The recordings of the radiated sound by a microphone are analyzed using a pre-trained deep learning model, evaluating the consistency of the physical sample generation method. The results demonstrate the ability to perform regression and classification tasks when fine tuning the deep learning model with the gathered data. The produced databases can properly train machine learning models, aiding in the investigation of alternative and cost-effective materials and geometries with relevant sound characteristics and in the development of accurate vibroacoustic numerical models for studying percussion instruments sound synthesis. Full article
(This article belongs to the Special Issue Recent Advances in Audio, Speech and Music Processing and Analysis)
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16 pages, 5551 KiB  
Article
Treatment of Pickle Wastewater under Varying Salinity Conditions within the Sequencing Batch Biofilm Reactor System
by Nuonan Shen, Hongyun Guo, Tingting Yao, Li Xu, Youxian Gao and Ping Yang
Water 2024, 16(9), 1312; https://doi.org/10.3390/w16091312 (registering DOI) - 06 May 2024
Abstract
Pickle wastewater is a highly saline organic effluent that poses a significant ecological risk. In this study, a sequencing batch biofilm reactor (SBBR) was used to treat such wastewater, and a denitrification system capable of simultaneously removing high levels of nitrogen and organic [...] Read more.
Pickle wastewater is a highly saline organic effluent that poses a significant ecological risk. In this study, a sequencing batch biofilm reactor (SBBR) was used to treat such wastewater, and a denitrification system capable of simultaneously removing high levels of nitrogen and organic matter was successfully established. Through salinity incremental increase, the system operated stably, and the removal rates of COD, TN, and NH4+-N could be maintained at about 96%, 93%, and 99% under the salinity of 3.0%. The effect of salinity on the structure and function of microbial communities in the reactor was investigated by high-throughput sequencing. The results showed that increasing salinity could reduce the diversity, change the structure, and reduce the functionality of the microbial community. Under high-salt conditions (salt content of 3.0%), salt-tolerant microorganisms such as Actinobacteriota became dominant populations. As salinity increased, NOB (nitrite oxidizing bacteria) was strongly inhibited, and its abundance decreased rapidly until it disappeared. Partial nitrification–denitrification (PND) gradually became the main denitrification pathway. In conclusion, this experiment not only shows that SBBR treatment of pickle wastewater has strong feasibility, but also provides a theoretical research basis for the engineering treatment of pickle wastewater. Full article
(This article belongs to the Section Wastewater Treatment and Reuse)
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17 pages, 2001 KiB  
Article
Microalgae Biomass Production from Rice Husk as Alternative Media Cultivation and Extraction of Phycocyanin Using 3D-Printed Ohmic Heating Reactor
by Gabriela Cid-Ibarra, Rosa M. Rodríguez-Jasso, Gilver Rosero-Chasoy, Ruth Belmares, Juan Carlos Contreras-Esquivel, Samanta Machado-Cepeda, Alejandra Cabello-Galindo and Héctor A. Ruiz
Foods 2024, 13(9), 1421; https://doi.org/10.3390/foods13091421 (registering DOI) - 06 May 2024
Abstract
Phycocyanin is a highly valued pigment present in Spirulina platensis biomass with applications in the food industry in terms of biorefinery concepts; specifically, its antioxidant and antimicrobial capacity are an advantage that could be incorporated into a food matrix. This study aims to [...] Read more.
Phycocyanin is a highly valued pigment present in Spirulina platensis biomass with applications in the food industry in terms of biorefinery concepts; specifically, its antioxidant and antimicrobial capacity are an advantage that could be incorporated into a food matrix. This study aims to use rice husk as an alternative culture medium for S. platensis biomass growth and phycocyanin extraction by ohmic heating processing using a 3D-printed reactor. S. platensis was cultivated in rice husk extract (RHE) from 0–100% (v/v). The highest content of microalgal biomass was 1.75 ± 0.01 g/L, with a specific growth rate of 0.125 ± 0.01 h−1. For the phycocyanin extraction under an ohmic heating process, a 3D-printed reactor was designed and built. To optimize phycocyanin extraction, a central composite rotatable design (CCDR) was evaluated, with three factors: time (min), temperature (°C), and pH. The highest phycocyanin content was 75.80 ± 0.98 mg/g in S. platensis biomass grown with rice husk extract. Ohmic heating is a promising method for rapid phycocyanin extraction, and rice husk as a culture medium is an alternative for the growth of S. platensis biomass in the integration of second- and third-generation biorefineries. Full article
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10 pages, 2568 KiB  
Article
Research on Low-Insertion-Loss Packaging Materials for DC-6 GHz Attenuation Chips
by Zhijie Wei, Shenglin Yu and Pengcheng Wei
Electronics 2024, 13(9), 1785; https://doi.org/10.3390/electronics13091785 (registering DOI) - 06 May 2024
Abstract
In the DC-6 GHz band, low-insertion-loss packaging materials were investigated to effectively reduce the heat generated during the working process of the attenuation chip. Based on the working principle of the attenuation chip, when the signal passes through the attenuation chip resistor network, [...] Read more.
In the DC-6 GHz band, low-insertion-loss packaging materials were investigated to effectively reduce the heat generated during the working process of the attenuation chip. Based on the working principle of the attenuation chip, when the signal passes through the attenuation chip resistor network, it results in energy loss. This means that the insertion loss of the chip generates heat, which leads to an uneven heat dissipation of the chip and thus functional failure. The microwave characteristics of the packaged joints were investigated using different packaging techniques. The results show that the S21 and S11 of the attenuation chip after nano-silver and Au80Sn20 packaging are optimal in the frequency band of DC-6 GHz, and the insertion loss is low compared with the commonly used packaging materials Sn60Pb40 and Sn96.5Ag3.5, which reduces the heat loss and improves the reliability of the attenuation chip packaging. Full article
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15 pages, 6472 KiB  
Article
Characterizing Edible Oils by Oblique-Incidence Reflectivity Difference Combined with Machine Learning Algorithms
by Xiaorong Sun, Yiran Hu, Cuiling Liu, Shanzhe Zhang, Sining Yan, Xuecong Liu and Kun Zhao
Foods 2024, 13(9), 1420; https://doi.org/10.3390/foods13091420 (registering DOI) - 06 May 2024
Abstract
Due to the significant price differences among different types of edible oils, expensive oils like olive oil are often blended with cheaper edible oils. This practice of adulteration in edible oils, aimed at increasing profits for producers, poses a major concern for consumers. [...] Read more.
Due to the significant price differences among different types of edible oils, expensive oils like olive oil are often blended with cheaper edible oils. This practice of adulteration in edible oils, aimed at increasing profits for producers, poses a major concern for consumers. Furthermore, adulteration in edible oils can lead to various health issues impacting consumer well-being. In order to meet the requirements of fast, non-destructive, universal, accurate, and reliable quality testing for edible oil, the oblique-incidence reflectivity difference (OIRD) method combined with machine learning algorithms was introduced to detect a variety of edible oils. The prediction accuracy of Gradient Boosting, K-Nearest Neighbor, and Random Forest models all exceeded 95%. Moreover, the contribution rates of the OIRD signal, DC signal, and fundamental frequency signal to the classification results were 45.7%, 34.1%, and 20.2%, respectively. In a quality evaluation experiment on olive oil, the feature importance scores of three signals reached 63.4%, 18.9%, and 17.6%. The results suggested that the feature importance score of the OIRD signal was significantly higher than that of the DC and fundamental frequency signals. The experimental results indicate that the OIRD method can serve as a powerful tool for detecting edible oils. Full article
(This article belongs to the Section Food Physics and (Bio)Chemistry)
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15 pages, 5670 KiB  
Article
Shaping of the Frequency Response of Photoacoustic Cells with Multi-Cavity Structures
by Wiktor Porakowski and Tomasz Starecki
Electronics 2024, 13(9), 1786; https://doi.org/10.3390/electronics13091786 (registering DOI) - 06 May 2024
Abstract
In the great majority of cases, the design of resonant photoacoustic cells is based on the use of resonators excited at the frequencies of their main resonances. This work presents a solution in which the use of a multi-cavity structure with the appropriate [...] Read more.
In the great majority of cases, the design of resonant photoacoustic cells is based on the use of resonators excited at the frequencies of their main resonances. This work presents a solution in which the use of a multi-cavity structure with the appropriate selection of the mechanical parameters of the cavities and the interconnecting ducts allows for the shaping of the frequency response of the cell. Such solutions may be particularly useful when the purpose of the designed cells is operation at multiple frequencies, e.g., in applications with the simultaneous detection of multiple gaseous compounds. The concept is tested with cells made using 3D printing technology. The measured frequency responses of the tested cells show very good agreement with the simulation results. This allows for an approach in which the development of a cell with the desired frequency response can be initially based on modeling, without the need for the time-consuming and expensive process of manufacturing and measuring numerous modifications of the cell. Full article
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15 pages, 324 KiB  
Review
Treatment Strategies of Colistin Resistance Acinetobacter baumannii Infections
by Andria Papazachariou, Renatos-Nikolaos Tziolos, Stamatis Karakonstantis, Petros Ioannou, George Samonis and Diamantis P. Kofteridis
Antibiotics 2024, 13(5), 423; https://doi.org/10.3390/antibiotics13050423 (registering DOI) - 06 May 2024
Abstract
Acinetobacter baumannii has emerged as a pressing challenge in clinical practice, mainly due to the development of resistance to multiple antibiotics, including colistin, one of the last-resort treatments. This review highlights all the possible mechanisms of colistin resistance and the genetic basis contributing [...] Read more.
Acinetobacter baumannii has emerged as a pressing challenge in clinical practice, mainly due to the development of resistance to multiple antibiotics, including colistin, one of the last-resort treatments. This review highlights all the possible mechanisms of colistin resistance and the genetic basis contributing to this resistance, such as modifications to lipopolysaccharide or lipid A structures, alterations in outer membrane permeability via porins and heteroresistance. In light of this escalating threat, the review also evaluates available treatment options. The development of new antibiotics (cefiderocol, sulbactam/durlobactam) although not available everywhere, and the use of various combinations and synergistic drug combinations (including two or more of the following: a polymyxin, ampicillin/sulbactam, carbapenems, fosfomycin, tigecycline/minocycline, a rifamycin, and aminoglycosides) are discussed in the context of overcoming colistin resistance of A. baumannii infections. Although most studied combinations are polymyxin-based combinations, non-polymyxin-based combinations have been emerging as promising options. However, clinical data remain limited and continued investigation is essential to determine optimal therapeutic strategies against colistin-resistant A. baumannii. Full article
12 pages, 4519 KiB  
Article
Endovascular Recanalization and Carotid Stenting: The New Approach to Restore Cerebral Perfusion during Aortic Dissection
by Maxim Agarkov, Kirill Kozlov, Ekaterina Senkina, Sergey Gornov, Natalia Linkova, Elena Kechaeva, Dmitrii Medvedev, Alexander Krasichkov, Anastasiia Dyatlova and Victoria Polyakova
J. Clin. Med. 2024, 13(9), 2716; https://doi.org/10.3390/jcm13092716 (registering DOI) - 06 May 2024
Abstract
A type A aortic dissection (TAAD) is a dangerous condition requiring emergency surgery. Due to the similarity of the symptoms of cerebral malperfusion in TAAD and the signs of ischemic stroke, a differential diagnosis of these diseases is not always available. Patients with [...] Read more.
A type A aortic dissection (TAAD) is a dangerous condition requiring emergency surgery. Due to the similarity of the symptoms of cerebral malperfusion in TAAD and the signs of ischemic stroke, a differential diagnosis of these diseases is not always available. Patients with TAAD after cerebral malperfusion can have a neurological deficit. Thrombolysis is performed in this case. It can worsen the patient’s condition and increase the risk of mortality and disability. The aim of the study is to evaluate the new approach to restoring cerebral perfusion during aortic dissection. This approach includes endovascular recanalization and carotid stenting. Methods: Two clinical cases of TAAD complicated by cerebral malperfusion are described. The first patient is 73 years old and was admitted as planned to perform transcatheter aortic valve implantation (TAVI) for grade III aortic stenosis. The patient underwent transcatheter aortic valve implantation (TAVI) on the second day after admission. The second patient is 60 years old and was hospitalized by an ambulance with strong hypertension and ischemia. The surgical correction of aortic dissection was postponed until the neurological status assessment in both patients. Results: The surgery to correct the aorta dissection was deemed inappropriate. The carotid arteries have been reanalyzed, and cerebral perfusion has been restored in a short time in both patients. Conclusion: Acute bilateral internal carotid occlusion is a potentially fatal TAAD outcome. Emergency endovascular recanalization and carotid stenting may be considered one of the few ways to restore cerebral perfusion. Full article
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18 pages, 5907 KiB  
Article
Influence of Nanoparticles in Lubricant on Sliding Contact of Atomic Rough Surfaces—A Molecular Dynamics Study
by Xuan Zheng, Lihong Su and Guanyu Deng
Lubricants 2024, 12(5), 160; https://doi.org/10.3390/lubricants12050160 (registering DOI) - 06 May 2024
Abstract
In this work, large-scale molecular dynamics (MD) computational simulations were performed in order to explore the sliding contact responses of rough surfaces with hexadecane lubricant and added nanoparticles. Simulation results revealed that the frictional state was dependent on the fluid, nanoparticle, and surface [...] Read more.
In this work, large-scale molecular dynamics (MD) computational simulations were performed in order to explore the sliding contact responses of rough surfaces with hexadecane lubricant and added nanoparticles. Simulation results revealed that the frictional state was dependent on the fluid, nanoparticle, and surface roughness. Three lubricating conditions were compared based on considerations of different amounts of fluid molecules. The lubricant was not able to separate the frictional contact surfaces if the quantity of lubricant molecules was insufficient. Particularly, there were no lubricating contributions when the amount of lubricant was too low, and the lubricant therefore only filled the pits in the surface roughness. Thus, the normal load was primarily supported by the contact between the two surfaces and nanoparticles, leading to significant surface morphology changes. In contrast, the frictional contact surfaces were able to be completely separated by the lubricant when there was a sufficient amount of fluid, and a very good lubricating effect could thus be achieved, resulting in a smaller friction force. In addition, the changes in surface morphology, contact area, and RMS are discussed in this paper, in order to reveal the dynamic frictional process. Full article
(This article belongs to the Special Issue Frictional and Wear Behaviors of Sliding Interfaces across Scales)
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18 pages, 620 KiB  
Article
Optimizing Requirements Prioritization for IoT Applications Using Extended Analytical Hierarchical Process and an Advanced Grouping Framework
by Sarah Kaleem, Muhammad Asim, Mohammed El-Affendi and Muhammad Babar
Future Internet 2024, 16(5), 160; https://doi.org/10.3390/fi16050160 (registering DOI) - 06 May 2024
Abstract
Effective requirement collection and prioritization are paramount within the inherently distributed nature of the Internet of Things (IoT) application. Current methods typically categorize IoT application requirements subjectively into inessential, desirable, and mandatory groups. This often leads to prioritization challenges, especially when dealing with [...] Read more.
Effective requirement collection and prioritization are paramount within the inherently distributed nature of the Internet of Things (IoT) application. Current methods typically categorize IoT application requirements subjectively into inessential, desirable, and mandatory groups. This often leads to prioritization challenges, especially when dealing with requirements of equal importance and when the number of requirements grows. This increases the complexity of the Analytical Hierarchical Process (AHP) to O(n2) dimensions. This research introduces a novel framework that integrates an enhanced AHP with an advanced grouping model to address these issues. This integrated approach mitigates the subjectivity found in traditional grouping methods and efficiently manages larger sets of requirements. The framework consists of two main modules: the Pre-processing Module and the Prioritization Module. The latter includes three units: the Grouping Processing Unit (GPU) for initial classification using a new grouping approach, the Review Processing Unit (RPU) for post-grouping assessment, and the AHP Processing Unit (APU) for final prioritization. This framework is evaluated through a detailed case study, demonstrating its ability to effectively streamline requirement prioritization in IoT applications, thereby enhancing design quality and operational efficiency. Full article
(This article belongs to the Special Issue Artificial Intelligence-Enabled Internet of Things (IoT))
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14 pages, 1611 KiB  
Article
Interprofessional Curriculum Delivery: Experience of a Primary Care Education Program
by Jessica A. Davila, Nancy D. Harada, Kathryn Wirtz Rugen, Stuart C. Gilman and Shubhada Sansgiry
Healthcare 2024, 12(9), 950; https://doi.org/10.3390/healthcare12090950 (registering DOI) - 06 May 2024
Abstract
Few post-graduate training programs offer a comprehensive curriculum that includes structured clinical experiences to teach interprofessional care. To address this need, the United States Department of Veterans Affairs, Office of Academic Affiliations funded the Centers of Excellence in Primary Care Education (CoEPCE) from [...] Read more.
Few post-graduate training programs offer a comprehensive curriculum that includes structured clinical experiences to teach interprofessional care. To address this need, the United States Department of Veterans Affairs, Office of Academic Affiliations funded the Centers of Excellence in Primary Care Education (CoEPCE) from 2011–2019 to provide interprofessional curricula for health profession trainees (HPTs), including physician residents, nurse practitioner residents, pharmacy residents, and psychology residents. We examined changes over time in curricular domains, system impacts, and program practices based on HPT survey data and the qualitative evaluation of narrative feedback. An annual survey was administered to participants. Indirect standardized ratios were calculated for interprofessional professional education (IPE) program domains, system impacts, and program practices. Qualitative responses were coded based on curricular domains and key program components. The study cohort included 369 HPTs. Site and profession standardized indirect ratios across all professions indicated improvements in curricular domains, system impacts, and program practices, with significant differences observed for associated health HPTs as compared to other HPTs for performance improvement. Qualitative data indicated that profession was associated with differences in perceptions of the curriculum. Although improvements occurred over time, our findings support the need for the thoughtful consideration of profession-specific identity characteristics when designing interprofessional curricula. Full article
(This article belongs to the Special Issue Health Professional Education and Primary Health Care)
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20 pages, 14746 KiB  
Article
Gibberellin Positively Regulates Tomato Resistance to Tomato Yellow Leaf Curl Virus (TYLCV)
by Chenwei Zhang, Dandan Wang, Yan Li, Zifan Wang, Zhiming Wu, Qingyin Zhang, Hongwei Jia, Xiaoxu Dong, Lianfen Qi, Jianhua Shi and Zhonglin Shang
Plants 2024, 13(9), 1277; https://doi.org/10.3390/plants13091277 (registering DOI) - 06 May 2024
Abstract
Tomato yellow leaf curl virus (TYLCV) is a prominent viral pathogen that adversely affects tomato plants. Effective strategies for mitigating the impact of TYLCV include isolating tomato plants from the whitefly, which is the vector of the virus, and utilizing transgenic lines that [...] Read more.
Tomato yellow leaf curl virus (TYLCV) is a prominent viral pathogen that adversely affects tomato plants. Effective strategies for mitigating the impact of TYLCV include isolating tomato plants from the whitefly, which is the vector of the virus, and utilizing transgenic lines that are resistant to the virus. In our preliminary investigations, we observed that the use of growth retardants increased the rate of TYLCV infection and intensified the damage to the tomato plants, suggesting a potential involvement of gibberellic acid (GA) in the conferring of resistance to TYLCV. In this study, we employed an infectious clone of TYLCV to inoculate tomato plants, which resulted in leaf curling and growth inhibition. Remarkably, this inoculation also led to the accumulation of GA3 and several other phytohormones. Subsequent treatment with GA3 effectively alleviated the TYLCV-induced leaf curling and growth inhibition, reduced TYLCV abundance in the leaves, enhanced the activity of antioxidant enzymes, and lowered the reactive oxygen species (ROS) levels in the leaves. Conversely, the treatment with PP333 exacerbated TYLCV-induced leaf curling and growth suppression, increased TYLCV abundance, decreased antioxidant enzyme activity, and elevated ROS levels in the leaves. The analysis of the gene expression profiles revealed that GA3 up-regulated the genes associated with disease resistance, such as WRKYs, NACs, MYBs, Cyt P450s, and ERFs, while it down-regulated the DELLA protein, a key agent in GA signaling. In contrast, PP333 induced gene expression changes that were the opposite of those caused by the GA3 treatment. These findings suggest that GA plays an essential role in the tomato’s defense response against TYLCV and acts as a positive regulator of ROS scavenging and the expression of resistance-related genes. Full article
(This article belongs to the Section Horticultural Science and Ornamental Plants)
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12 pages, 989 KiB  
Review
A Focused Review on Wildfire Evacuation and Infrastructure Resilience in Canada: Trends and Insights (2013–2023)
by Nima Karimi
Fire 2024, 7(5), 161; https://doi.org/10.3390/fire7050161 (registering DOI) - 06 May 2024
Abstract
This review paper investigates the landscape of wildfire-related studies with a focus on infrastructure and evacuations across Canadian provinces, revealing a predominant focus on Alberta, particularly after the 2016 Fort McMurray wildfire. The aftermath of this event has heightened attention to the unique [...] Read more.
This review paper investigates the landscape of wildfire-related studies with a focus on infrastructure and evacuations across Canadian provinces, revealing a predominant focus on Alberta, particularly after the 2016 Fort McMurray wildfire. The aftermath of this event has heightened attention to the unique challenges faced during evacuations, emphasizing the urgent need for heightened awareness and preparedness, especially in the vulnerable northern communities of Alberta. Studies beyond Alberta contribute to understanding Canadian wildfire dynamics. However, a noticeable research gap in British Columbia raises concerns about research prioritization and resource allocation despite heightened wildfire activity. The fact that some provinces are contributing less than 4.2%, such as Quebec, Saskatchewan, Ontario, Northwest Territories, Yukon, and the Prairies, might be attributed to regional variations influenced by historical wildfire frequency and population density. Thematic analysis categorizing studies into “community support/resilience”, “evacuation efficiency”, and “infrastructure protection/raising awareness” provides nuanced insights. The dominance of the “community support/resilience” category, comprising over 40% of studies, signifies a societal shift towards proactive community engagement. Balanced representation in the “evacuation efficiency” and “infrastructure protection/raising awareness” categories, each contributing over 29%, reflects a collective effort to glean lessons from past evacuations and enhance community preparedness. Temporal trends and thematic analyses spotlight a commitment to continuous improvement, adaptability to emerging challenges, and a growing recognition of the multifaceted aspects of wildfire management. The evolving emphasis on community involvement, responsiveness to changing evacuation dynamics, and heightened awareness of infrastructure protection underscores the proactive stance of the research community, providing insights for shaping future research priorities, policy frameworks, and community resilience strategies in the face of evolving wildfire threats in Canada. Full article
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12 pages, 1431 KiB  
Article
Trends in Shoulder Arthroplasty in Germany: A 10-Year Epidemiological Analysis of Patients with Primary Osteoarthritis of the Shoulder
by Felix Frederik Hochberger, Philipp Herrmann, Maximilian Rudert, Kilian List and Ioannis Stratos
Healthcare 2024, 12(9), 949; https://doi.org/10.3390/healthcare12090949 (registering DOI) - 06 May 2024
Abstract
Shoulder arthroplasty has significantly gained popularity in orthopedic surgery, driven by progress in prosthesis design and surgical techniques. This study explored the epidemiology of shoulder arthroplasty, analyzing healthcare data from 2012 to 2022 for primary osteoarthritis of the shoulder. The data included patient [...] Read more.
Shoulder arthroplasty has significantly gained popularity in orthopedic surgery, driven by progress in prosthesis design and surgical techniques. This study explored the epidemiology of shoulder arthroplasty, analyzing healthcare data from 2012 to 2022 for primary osteoarthritis of the shoulder. The data included patient demographics and types of surgical procedures. Data analysis indicates a higher utilization rate of reverse total shoulder arthroplasty (RTSA; n = 41,251) over total- (TSA; n = 18,679) and hemiarthroplasty (HSA; n = 12,827) for primary shoulder osteoarthritis. Overall, a significant increase in RTSA procedures from n = 2237 (2012) to n = 5415 (2022) was observed, representing more than a two-fold increase of 121.1%. The relative proportion of RTSA among all types of shoulder arthroplasty increased from 39% (2012) to 68.6% (2022), while HSA decreased and TSA essentially remained constant. Age analysis identified the following peaks: RTSA, 77 ± 7 y; HSA, 68 ± 12 y; and TSA, 67 ± 10 y. Among the over 60s, significantly more women were treated with any type of prosthesis, whereas in young patients (45 to 59 y), more men received HSA or TSA. Our study confirms that RTSA has become the preferred choice for elderly patients in Germany, reflecting the prevailing preference despite varying patient ages and conditions, with a noted difference in sex in treatment prevalence. Full article
(This article belongs to the Special Issue Health Service Interventions in Musculoskeletal Disorders)
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27 pages, 2011 KiB  
Review
The Intersection of HIV and Pulmonary Vascular Health: From HIV Evolution to Vascular Cell Types to Disease Mechanisms
by Amanda K. Garcia and Sharilyn Almodovar
J. Vasc. Dis. 2024, 3(2), 174-200; https://doi.org/10.3390/jvd3020015 (registering DOI) - 06 May 2024
Abstract
People living with HIV (PLWH) face a growing burden of chronic diseases, owing to the combinations of aging, environmental triggers, lifestyle choices, and virus-induced chronic inflammation. The rising incidence of pulmonary vascular diseases represents a major concern for PLWH. The study of HIV-associated [...] Read more.
People living with HIV (PLWH) face a growing burden of chronic diseases, owing to the combinations of aging, environmental triggers, lifestyle choices, and virus-induced chronic inflammation. The rising incidence of pulmonary vascular diseases represents a major concern for PLWH. The study of HIV-associated pulmonary vascular complications ideally requires a strong understanding of pulmonary vascular cell biology and HIV pathogenesis at the molecular level for effective applications in infectious diseases and vascular medicine. Active HIV infection and/or HIV proteins disturb the delicate balance between vascular tone and constriction, which is pivotal for maintaining pulmonary vascular health. One of the defining features of HIV is its high genetic diversity owing to several factors including its high mutation rate, recombination between viral strains, immune selective pressures, or even geographical factors. The intrinsic HIV genetic diversity has several important implications for pathogenic outcomes of infection and the overall battle to combat HIV. Challenges in the field present themselves from two sides of the same coin: those imposed by the virus itself and those stemming from the host. The field may be advanced by further developing in vivo and in vitro models that are well described for both pulmonary vascular diseases and HIV for mechanistic studies. In essence, the study of HIV-associated pulmonary vascular complications requires a multidisciplinary approach, drawing upon insights from both infectious diseases and vascular medicine. In this review article, we discuss the fundamentals of HIV virology and their impact on pulmonary disease, aiming to enhance the understanding of either area or both simultaneously. Bridging the gap between preclinical research findings and clinical practice is essential for improving patient care. Addressing these knowledge gaps requires interdisciplinary collaborations, innovative research approaches, and dedicated efforts to prioritize HIV-related pulmonary complications on the global research agenda. Full article
(This article belongs to the Section Cardiovascular Diseases)
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23 pages, 7657 KiB  
Article
An Interactive Feeder to Induce and Assess Emotions from Vocalisations of Chickens
by Antonis Golfidis, Buddhamas Pralle Kriengwatana, Mina Mounir and Tomas Norton
Animals 2024, 14(9), 1386; https://doi.org/10.3390/ani14091386 (registering DOI) - 06 May 2024
Abstract
Understanding the emotional states of animals is a long-standing research endeavour that has clear applications in animal welfare. Vocalisations are emerging as a promising way to assess both positive and negative emotional states. However, the vocal expression of emotions in birds is a [...] Read more.
Understanding the emotional states of animals is a long-standing research endeavour that has clear applications in animal welfare. Vocalisations are emerging as a promising way to assess both positive and negative emotional states. However, the vocal expression of emotions in birds is a relatively unexplored research area. The goal of this study was to develop an interactive feeding system that would elicit positive and negative emotional states, and collect recordings of the vocal expression of these emotions without human interference. In this paper, the mechatronic design and development of the feeder is described. Design choices were motivated by the desire for the hens to voluntarily interact with the feeder and experience the different stimuli that were designed to induce (1) positive low-arousal, (2) positive high-arousal, (3) negative low-arousal, and (4) negative high-arousal states. The results showed that hens were motivated to engage with the feeder despite the risk of receiving negative stimuli and that this motivation was sustained for at least 1 week. The potential of using the interactive feeder to analyse chicken vocalisations related to emotional valence and arousal is being explored, offering a novel proof of concept in animal welfare research. Preliminary findings suggest that hens vocalised in response to all four stimulus types, with the number of vocalisations, but not the probability of vocalising, distinguishing between low- and high-arousal states. Thus, the proposed animal–computer interaction design has potential to be used as an enrichment device and for future experiments on vocal emotions in birds. Full article
(This article belongs to the Special Issue Animal–Computer Interaction: Advances and Opportunities)
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17 pages, 561 KiB  
Article
An Adaptive Contextual Relation Model for Improving Response Generation
by Meiqi Wang, Shiyu Tian, Caixia Yuan and Xiaojie Wang
Appl. Sci. 2024, 14(9), 3941; https://doi.org/10.3390/app14093941 (registering DOI) - 06 May 2024
Abstract
Context modeling has always been the groundwork for the dialogue response generation task, yet it presents challenges due to the loose context relations among open-domain dialogue sentences. Introducing simulated dialogue futures has been proposed as a solution to mitigate the problem of low [...] Read more.
Context modeling has always been the groundwork for the dialogue response generation task, yet it presents challenges due to the loose context relations among open-domain dialogue sentences. Introducing simulated dialogue futures has been proposed as a solution to mitigate the problem of low history–response relevance. However, these approaches simply assume that the history and future of a dialogue have the same effect on response generation. In reality, the coherence between dialogue sentences varies, and thus, history and the future are not uniformly helpful in response prediction. Consequently, determining and leveraging the relevance between history–response and response–future to aid in response prediction emerges as a pivotal concern. This paper addresses this concern by initially establishing three context relations of response and its context (history and future), reflecting the relevance between the response and preceding and following sentences. Subsequently, we annotate response contextual relation labels on a large-scale dataset, DailyDialog (DD). Leveraging these relation labels, we propose a response generation model that adaptively integrates contributions from preceding and succeeding sentences guided by explicit relation labels. This approach mitigates the impact in cases of lower relevance and amplifies contributions in cases of higher relevance, thus improving the capability of context modeling. Experimental results on public dataset DD demonstrate that our response generation model significantly enhances coherence by 3.02% in long sequences (4-gram) and augments bi-gram diversity by 17.67%, surpassing the performance of previous models. Full article
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10 pages, 779 KiB  
Review
A Review of Endobronchial-Ultrasound-Guided Transbronchial Intranodal Forceps Biopsy and Cryobiopsy
by Michel Chalhoub, Bino Joseph and Sudeep Acharya
Diagnostics 2024, 14(9), 965; https://doi.org/10.3390/diagnostics14090965 (registering DOI) - 06 May 2024
Abstract
Benign and malignant mediastinal lesions are not infrequently encountered in clinical practice. Mediastinoscopy has long been considered the gold standard in evaluating mediastinal pathology. Since its introduction into clinical practice, endobronchial-ultrasonography-guided transbronchial fine needle aspiration (EBUS-TBNA) has replaced mediastinoscopy as the initial procedure [...] Read more.
Benign and malignant mediastinal lesions are not infrequently encountered in clinical practice. Mediastinoscopy has long been considered the gold standard in evaluating mediastinal pathology. Since its introduction into clinical practice, endobronchial-ultrasonography-guided transbronchial fine needle aspiration (EBUS-TBNA) has replaced mediastinoscopy as the initial procedure of choice to evaluate mediastinal lesions and to stage lung cancer. Its diagnostic yield in benign mediastinal lesions and less common malignancies, however, has remained limited. This has led different proceduralists to investigate additional procedures to improve the diagnostic yield of EBUS-TBNA. In recent years, different published reports concluded that the addition of EBUS-guided intranodal forceps biopsy (IFB) and transbronchial cryobiopsy (TBCB) to EBUS-TBNA increases the diagnostic yield especially in benign mediastinal lesions and uncommon mediastinal malignancies. The purpose of this review is to describe how EBUS-IFB and EBUS-TBCB are performed, to compare their diagnostic yields, and to discuss their limitations and their potential complications. In addition, the review will conclude with a proposed algorithm on how to incorporate EBUS-IFB and EBUS-TBCB into clinical practice. Full article
(This article belongs to the Special Issue Recent Advances in Diagnostic Bronchoscopy)
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