The 2023 MDPI Annual Report has
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13 pages, 840 KiB  
Article
Dose Escalation Can Enhance the Therapeutic Potential of Radial Extracorporeal Shock-Wave Therapy in the Treatment of Plantar Fasciitis in Runners
by Sebastian Szajkowski, Jarosław Pasek and Grzegorz Cieślar
Medicina 2024, 60(5), 766; https://doi.org/10.3390/medicina60050766 (registering DOI) - 06 May 2024
Abstract
Background and Objectives: Treatment of chronic plantar fasciitis is challenging given that there are various of available treatment options with no clear gold standard. The aim of the study was to examine the dose-escalation effect of rESWT on the biomechanical parameters of the [...] Read more.
Background and Objectives: Treatment of chronic plantar fasciitis is challenging given that there are various of available treatment options with no clear gold standard. The aim of the study was to examine the dose-escalation effect of rESWT on the biomechanical parameters of the plantar fascia and pain ailments. Materials and Methods: In the experimental group (n = 30), the intensity of the shock wave was increased every two subsequent treatment sessions. In the control group (n = 32), the treatment parameters were not changed. In both groups, six treatments were performed, with two treatment sessions a week. In order to assess the biomechanical parameters of the plantar fascia, myotonometric measurements were performed. The pain intensity was assessed using the Visual Analog Scale (VAS). Results: The tension of the plantar fascia attachment in the experimental group decreased from 27.69 ± 2.06 [Hz] before treatment to 26.29 ± 1.69 [Hz] after treatment (p = 0.009) and to 26.03 ± 2.15 [Hz] 1 month after the beginning of treatment (p = 0.003). In the control group, the frequency results did not change significantly (p > 0.05). Flexibility increased in both groups. The test results before treatment and 1 month after the beginning of the treatment showed statistical significance in the experimental group (p = 0.001) vs. (p = 0.002) in the control group. The differences were not statistically significant between groups (p > 0.05). The assessment of pain intensity carried out 1 month after the end of treatment in the experimental group amounted to 3.14 ± 2.28 points, which was statistically significantly lower compared to that in the control group, where it amounted to 5.14 ± 1.92 points. (p < 0.001). Conclusions: The use of rESWT performed with an increasing intensity of impact during subsequent treatment procedures demonstrated greater effectiveness in improving the biomechanical parameters of the plantar fascia and was also more effective in reducing the pain ailments. Our results are encouraging. The dose escalation in the treatment cycle is worth considering. To prove that this method of treatment is more effective, a randomized controlled trial should be carried out on a representative sample. Full article
(This article belongs to the Section Sports Medicine and Sports Traumatology)
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26 pages, 929 KiB  
Systematic Review
Effect of Sustainably Sourced Protein Consumption on Nutrient Intake and Gut Health in Older Adults: A Systematic Review
by Debra Jones, Carlos Celis-Morales, Stuart R. Gray, Douglas J. Morrison, Susan E. Ozanne, Mahek Jain, Lewis R. Mattin and Sorrel Burden
Nutrients 2024, 16(9), 1398; https://doi.org/10.3390/nu16091398 (registering DOI) - 06 May 2024
Abstract
Diet is integral to the healthy ageing process and certain diets can mitigate prolonged and deleterious inflammation. This review aims to assess the impact of diets high in sustainably sourced proteins on nutrient intake, gut, and age-related health in older adults. A systematic [...] Read more.
Diet is integral to the healthy ageing process and certain diets can mitigate prolonged and deleterious inflammation. This review aims to assess the impact of diets high in sustainably sourced proteins on nutrient intake, gut, and age-related health in older adults. A systematic search of the literature was conducted on 5 September 2023 across multiple databases and sources. Studies assessing sustainably sourced protein consumption in community dwelling older adults (≥65 years) were included. Risk of bias (RoB) was assessed using ‘RoB 2.0′ and ‘ROBINS-E’. Narrative synthesis was performed due to heterogeneity of studies. Twelve studies involving 12,166 older adults were included. Nine studies (n = 10,391) assessed habitual dietary intake and had some RoB concerns, whilst three studies (n = 1812), two with low and one with high RoB, conducted plant-based dietary interventions. Increased adherence to sustainably sourced diets was associated with improved gut microbial factors (n = 4640), healthier food group intake (n = 2142), and increased fibre and vegetable protein intake (n = 1078). Sustainably sourced diets positively impacted on gut microbiota and healthier intake of food groups, although effects on inflammatory outcomes and health status were inconclusive. Future research should focus on dietary interventions combining sustainable proteins and fibre to evaluate gut barrier function and consider inflammatory and body composition outcomes in older adults. Full article
(This article belongs to the Section Geriatric Nutrition)
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20 pages, 2308 KiB  
Article
Water Banking as a Strategy for the Management and Conservation of a Critical Resource: A Case Study from Tunisia’s Medjerda River Basin (MRB)
by Aymen Sawassi, Roula Khadra and Brian Crookston
Sustainability 2024, 16(9), 3875; https://doi.org/10.3390/su16093875 (registering DOI) - 06 May 2024
Abstract
The increasingly adverse impacts of climate change (e.g., rainfall patterns, droughts, and floods), coupled with the ever-increasing water demands, are often translated into a contingent liability for water users’ communities. Additional complexities arise due to competing priorities, water rights, and transboundary water sources. [...] Read more.
The increasingly adverse impacts of climate change (e.g., rainfall patterns, droughts, and floods), coupled with the ever-increasing water demands, are often translated into a contingent liability for water users’ communities. Additional complexities arise due to competing priorities, water rights, and transboundary water sources. Therefore, conventional water management practices should shift toward more comprehensive and responsive integrative approaches, even for systems with limited data. Furthermore, water managers must prioritize dynamic and interactive management techniques for existing systems. One such management technique is water banking, which is the focus of this study. Herein, a dynamic interactive water allocation model, which encompasses the water managers and heterogeneous parties with competing demands, is developed. The voluntary sales of water shares between parties are illustrated through the specific case of the Medjerda River in Tunisia, an excellent example of a transboundary basin with limited hydrologic data and conflicting water use requirements between its upstream and downstream sectors. A set of scenarios is developed for the first analysis with this model: two management scenarios that include the no-water trade and the water banking option; three demand scenarios that include a combination of steady-, low-, and high-water demand conditions; and two hydrologic scenarios that include dry and wet conditions. Based on an economic model, the economic impacts of water banking are calculated using estimates of the costs of water shortages brought to users that illustrate the magnitude. The results show that the water banking technique can improve water resource availability by optimizing the management, operation, and conservation of natural and artificial water storage systems and water distribution infrastructure. Specifically, water banking can offset users’ profit losses during severe conditions (i.e., drought), even with limited hydrologic data. This water management technique would allow the Tunisian government to minimize the economic impacts on farmers from drought and to plan for future uncertainties by optimizing the water storage potential in years of abundant rainfall. Full article
(This article belongs to the Section Sustainable Water Management)
20 pages, 29850 KiB  
Article
Comprehensive Performance Evaluation between Visual SLAM and LiDAR SLAM for Mobile Robots: Theories and Experiments
by Yu-Lin Zhao, Yi-Tian Hong and Han-Pang Huang
Appl. Sci. 2024, 14(9), 3945; https://doi.org/10.3390/app14093945 (registering DOI) - 06 May 2024
Abstract
SLAM (Simultaneous Localization and Mapping), primarily relying on camera or LiDAR (Light Detection and Ranging) sensors, plays a crucial role in robotics for localization and environmental reconstruction. This paper assesses the performance of two leading methods, namely ORB-SLAM3 and SC-LeGO-LOAM, focusing on localization [...] Read more.
SLAM (Simultaneous Localization and Mapping), primarily relying on camera or LiDAR (Light Detection and Ranging) sensors, plays a crucial role in robotics for localization and environmental reconstruction. This paper assesses the performance of two leading methods, namely ORB-SLAM3 and SC-LeGO-LOAM, focusing on localization and mapping in both indoor and outdoor environments. The evaluation employs artificial and cost-effective datasets incorporating data from a 3D LiDAR and an RGB-D (color and depth) camera. A practical approach is introduced for calculating ground-truth trajectories and during benchmarking, reconstruction maps based on ground truth are established. To assess the performance, ATE and RPE are utilized to evaluate the accuracy of localization; standard deviation is employed to compare the stability during the localization process for different methods. While both algorithms exhibit satisfactory positioning accuracy, their performance is suboptimal in scenarios with inadequate textures. Furthermore, 3D reconstruction maps established by the two approaches are also provided for direct observation of their differences and the limitations encountered during map construction. Moreover, the research includes a comprehensive comparison of computational performance metrics, encompassing Central Processing Unit (CPU) utilization, memory usage, and an in-depth analysis. This evaluation revealed that Visual SLAM requires more CPU resources than LiDAR SLAM, primarily due to additional data storage requirements, emphasizing the impact of environmental factors on resource requirements. In conclusion, LiDAR SLAM is more suitable for the outdoors due to its comprehensive nature, while Visual SLAM excels indoors, compensating for sparse aspects in LiDAR SLAM. To facilitate further research, a technical guide was also provided for the researchers in related fields. Full article
(This article belongs to the Section Robotics and Automation)
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13 pages, 1631 KiB  
Article
Natural Contamination of Rice with Ustiloxins and the Connection with Climate Conditions in Southern China
by Xuexue Miao, Ying Miao, Yang Liu, Shuhua Tao, Huabin Zheng, Na Kuang, Jiemin Wang and Qiyuan Tang
Agronomy 2024, 14(5), 976; https://doi.org/10.3390/agronomy14050976 (registering DOI) - 06 May 2024
Abstract
Mycotoxins often contaminate rice, which are the secondary metabolites of fungi. Ustiloxins, a type of mycotoxin that has often been overlooked, pose a significant risk to human health. Therefore, identifying and controlling the pollution of ustiloxins in rice is required. In this study, [...] Read more.
Mycotoxins often contaminate rice, which are the secondary metabolites of fungi. Ustiloxins, a type of mycotoxin that has often been overlooked, pose a significant risk to human health. Therefore, identifying and controlling the pollution of ustiloxins in rice is required. In this study, we examined the natural contamination of rice with ustiloxins and their link to climate conditions. A total of 300 paddy samples were collected from six regions in southern China, and concentrations of ustiloxins A, B, C, D, and F were analyzed by liquid chromatography–tandem mass spectrometry (LC-MS/MS). Results showed that the occurrence of ustiloxins A, B, C, D, and F in paddies was found to be 55.7%, 41.3%, 29.0%, 93.7%, and 96.7%, respectively. Ustiloxin A had the highest mean (177.8 µg/kg) and maximum (3620.9 µg/kg) concentration, followed, in order, by ustiloxins C, B, D, and F. Furthermore, ustiloxin levels were significantly different depending on their origin, with the highest concentration in rice from Changde and Yueyang. And the regional difference in ustiloxins was related to the diversity of climate. A positive correlation between ustiloxin occurrence and mean humidity and precipitation was found in July and August of different regions, while mean temperature indicated a negative dependence. This is an essential survey of the contamination of rice with ustiloxins throughout southern China. The influence of climatic conditions on ustiloxins contamination was evaluated for the first time in our study. Overall, the rice samples examined in this study exhibited a high distribution of ustiloxins, suggesting that regulatory limits and the establishment of maximum allowable levels of ustiloxins in rice are necessary. This study provides a basis and guidance for the pollution situation and control strategy of ustiloxins in China. Full article
(This article belongs to the Section Agricultural Biosystem and Biological Engineering)
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22 pages, 2821 KiB  
Article
Enhancing Fetal Electrocardiogram Signal Extraction Accuracy through a CycleGAN Utilizing Combined CNN–BiLSTM Architecture
by Yuyao Yang, Lin Chen and Shuicai Wu
Sensors 2024, 24(9), 2948; https://doi.org/10.3390/s24092948 (registering DOI) - 06 May 2024
Abstract
The fetal electrocardiogram (FECG) records changes in the graph of fetal cardiac action potential during conduction, reflecting the developmental status of the fetus in utero and its physiological cardiac activity. Morphological alterations in the FECG can indicate intrauterine hypoxia, fetal distress, and neonatal [...] Read more.
The fetal electrocardiogram (FECG) records changes in the graph of fetal cardiac action potential during conduction, reflecting the developmental status of the fetus in utero and its physiological cardiac activity. Morphological alterations in the FECG can indicate intrauterine hypoxia, fetal distress, and neonatal asphyxia early on, enhancing maternal and fetal safety through prompt clinical intervention, thereby reducing neonatal morbidity and mortality. To reconstruct FECG signals with clear morphological information, this paper proposes a novel deep learning model, CBLS-CycleGAN. The model’s generator combines spatial features extracted by the CNN with temporal features extracted by the BiLSTM network, thus ensuring that the reconstructed signals possess combined features with spatial and temporal dependencies. The model’s discriminator utilizes PatchGAN, employing small segments of the signal as discriminative inputs to concentrate the training process on capturing signal details. Evaluating the model using two real FECG signal databases, namely “Abdominal and Direct Fetal ECG Database” and “Fetal Electrocardiograms, Direct and Abdominal with Reference Heartbeat Annotations”, resulted in a mean MSE and MAE of 0.019 and 0.006, respectively. It detects the FQRS compound wave with a sensitivity, positive predictive value, and F1 of 99.51%, 99.57%, and 99.54%, respectively. This paper’s model effectively preserves the morphological information of FECG signals, capturing not only the FQRS compound wave but also the fetal P-wave, T-wave, P-R interval, and ST segment information, providing clinicians with crucial diagnostic insights and a scientific foundation for developing rational treatment protocols. Full article
(This article belongs to the Section Biomedical Sensors)
14 pages, 3566 KiB  
Article
Effect of Climate Evolution on the Dynamics of the Wildfires in Greece
by Nikolaos Iliopoulos, Iasonas Aliferis and Michail Chalaris
Fire 2024, 7(5), 162; https://doi.org/10.3390/fire7050162 (registering DOI) - 06 May 2024
Abstract
Understanding the potential effects of climate change on forest fire behavior and the resulting release of combustion products is critical for effective mitigation strategies in Greece. This study utilizes data from the MAGICC 2.4 (Model for the Assessment of Greenhouse Gas-Induced Climate Change) [...] Read more.
Understanding the potential effects of climate change on forest fire behavior and the resulting release of combustion products is critical for effective mitigation strategies in Greece. This study utilizes data from the MAGICC 2.4 (Model for the Assessment of Greenhouse Gas-Induced Climate Change) climate model and the SCENGEN 2.4 (SCENarioGENerator) database to assess these impacts. By manipulating various model parameters such as climate sensitivity, scenario, time period, and global climate models (GCMs) within the SCENGEN 2.4 database, we analyzed climatic trends affecting forest fire generation and evolution. The results reveal complex and nuanced findings, indicating a need for further investigation. Case studies are conducted using the FARSITE 4 (Fire Area Simulator) model, incorporating meteorological changes derived from climate trends. Simulations of two fires in East Attica, accounting for different fuel and meteorological conditions, demonstrate an increase in the rate of combustion product release. This underscores the influence of changing meteorological parameters on forest fire dynamics and highlights the importance of proactive measures to mitigate future risks. Our findings emphasize the urgency of addressing climate change impacts on wildfire behavior to safeguard environmental and public health in Greece. Full article
(This article belongs to the Special Issue Effects of Climate Change on Fire Danger)
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23 pages, 4807 KiB  
Article
Influence of Power Fluctuation on Ni-Based Electrode Degradation and Hydrogen Evolution Reaction Performance in Alkaline Water Splitting: Probing the Effect of Renewable Energy on Water Electrolysis
by Congying Liu, Bing Lin, Hailong Zhang, Yingying Wang, Hangzhou Wang, Junlei Tang and Caineng Zou
Catalysts 2024, 14(5), 307; https://doi.org/10.3390/catal14050307 (registering DOI) - 06 May 2024
Abstract
The combination of water electrolysis and renewable energy to produce hydrogen is a promising way to solve the climate and energy crisis. However, the fluctuating characteristics of renewable energy not only present a significant challenge to the use of water electrolysis electrodes, but [...] Read more.
The combination of water electrolysis and renewable energy to produce hydrogen is a promising way to solve the climate and energy crisis. However, the fluctuating characteristics of renewable energy not only present a significant challenge to the use of water electrolysis electrodes, but also limit the development of the hydrogen production industry. In this study, the effects of three different types of waveforms (square, step, and triangle, which were used to simulate the power input of renewable energy) on the electrochemical catalysis behavior of Ni plate cathodes for HER was investigated. During the test, the HER performance of the Ni cathode increased at first and then slightly decreased. The fluctuating power led to the degradation of the Ni cathode surface, which enhanced the catalysis effect by increasing the catalytic area and the active sites. However, prolonged operation under power fluctuations could have damaged the morphology of the electrode surface and the substances comprising this surface, potentially resulting in a decline in catalytic efficiency. In addition, the electrochemical catalysis behavior of the prepared FeNiMo-LDH@NiMo/SS cathode when subjected to square-wave potential with different fluctuation amplitudes was also extensively studied. A larger amplitude of fluctuating power led to a change in the overpotential and stability of the LDH electrode, which accelerated the degradation of the cathode. This research provides a technological basis for the coupling of water electrolysis and fluctuating renewable energy and thus offers assistance to the development of the “green hydrogen” industry. Full article
(This article belongs to the Section Electrocatalysis)
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22 pages, 4562 KiB  
Article
Quantitative Evaluation of Sustainable Marketing Effectiveness: A Polish Case Study
by Pawel Tadeusz Kazibudzki and Tomasz Witold Trojanowski
Sustainability 2024, 16(9), 3877; https://doi.org/10.3390/su16093877 (registering DOI) - 06 May 2024
Abstract
This research investigates the sustainable marketing effectiveness of Poland’s fruit and vegetable industry using a seminal approach to analyze the interconnected dynamics among all factors and highlight pivotal elements through a structural model. Methodologically, the research used a sample of 216 companies utilizing [...] Read more.
This research investigates the sustainable marketing effectiveness of Poland’s fruit and vegetable industry using a seminal approach to analyze the interconnected dynamics among all factors and highlight pivotal elements through a structural model. Methodologically, the research used a sample of 216 companies utilizing a comprehensive survey to gauge various dimensions of sustainable marketing, including the environmental and social aspects of production, pricing, distribution and promotional activities. The findings reveal a nuanced landscape of sustainability practices within the industry. While there is a commendable level of awareness and some positive strides in certain areas such as employee-focused social aspects, other domains lag significantly, particularly consumer-focused social aspects and sustainable promotional activities. The study highlights the need for a more concerted and integrated approach towards sustainability, emphasizing the necessity of balancing economic goals with environmental stewardship and social responsibility. These insights bear significant implications for both research and practice. Practically, the study offers industry stakeholders a detailed understanding of the current state of sustainable practices pinpointing areas of strength and opportunities for improvement. It underlines the originality and value of employing a sophisticated analytical approach in assessing and enhancing the sustainability of marketing practices in the industry. Full article
(This article belongs to the Special Issue Sustainable Management and Consumer Behavior Studies)
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15 pages, 2584 KiB  
Article
Alcohol Consumption Is a Coping Mechanism for Male Patients with Severe Anxiety Disorders Treated with Antidepressants Monotherapy
by Mădălina Iuliana Mușat, Felicia Militaru, Ion Udriștoiu, Smaranda Ioana Mitran and Bogdan Cătălin
J. Clin. Med. 2024, 13(9), 2723; https://doi.org/10.3390/jcm13092723 (registering DOI) - 06 May 2024
Abstract
Anxiety disorders are prevalent mental health conditions often accompanied by various comorbidities. The association between anxiety and liver disease, as well as fluctuations in blood sugar levels, highlights the importance of carefully evaluating patients with anxiety undergoing antidepressant therapy. The aim of this [...] Read more.
Anxiety disorders are prevalent mental health conditions often accompanied by various comorbidities. The association between anxiety and liver disease, as well as fluctuations in blood sugar levels, highlights the importance of carefully evaluating patients with anxiety undergoing antidepressant therapy. The aim of this study was to conduct a comparative assessment of liver function and blood glucose levels in patients diagnosed with anxiety disorders while considering potential gender-specific differences. Methods: An analysis was conducted over a 24-month period. This study included 88 patients diagnosed with anxiety disorders, with symptoms severe enough to require hospitalization, aged 18 or older, undergoing antidepressant monotherapy, without any additional pathologies. Liver enzymes (AST, ALT, GGT), AST/ALT ratio, and blood glucose levels were measured and compared. Results: While no significant differences were found between antidepressant classes, increased GGT levels were observed in men older than 40 years compared to women of the same age, suggesting that alcohol consumption may be a coping mechanism for anxiety. This gender difference was not observed among young patients. Conclusions: Early detection of alcohol consumption is essential in patients with anxiety disorders in order to prevent alcohol-related liver damage and to adjust the management of both conditions accordingly. Full article
(This article belongs to the Section Mental Health)
16 pages, 1684 KiB  
Review
Motion Capture Technology in Sports Scenarios: A Survey
by Xiang Suo, Weidi Tang and Zhen Li
Sensors 2024, 24(9), 2947; https://doi.org/10.3390/s24092947 (registering DOI) - 06 May 2024
Abstract
Motion capture technology plays a crucial role in optimizing athletes’ skills, techniques, and strategies by providing detailed feedback on motion data. This article presents a comprehensive survey aimed at guiding researchers in selecting the most suitable motion capture technology for sports science investigations. [...] Read more.
Motion capture technology plays a crucial role in optimizing athletes’ skills, techniques, and strategies by providing detailed feedback on motion data. This article presents a comprehensive survey aimed at guiding researchers in selecting the most suitable motion capture technology for sports science investigations. By comparing and analyzing the characters and applications of different motion capture technologies in sports scenarios, it is observed that cinematography motion capture technology remains the gold standard in biomechanical analysis and continues to dominate sports research applications. Wearable sensor-based motion capture technology has gained significant traction in specialized areas such as winter sports, owing to its reliable system performance. Computer vision-based motion capture technology has made significant advancements in recognition accuracy and system reliability, enabling its application in various sports scenarios, from single-person technique analysis to multi-person tactical analysis. Moreover, the emerging field of multimodal motion capture technology, which harmonizes data from various sources with the integration of artificial intelligence, has proven to be a robust research method for complex scenarios. A comprehensive review of the literature from the past 10 years underscores the increasing significance of motion capture technology in sports, with a notable shift from laboratory research to practical training applications on sports fields. Future developments in this field should prioritize research and technological advancements that cater to practical sports scenarios, addressing challenges such as occlusion, outdoor capture, and real-time feedback. Full article
(This article belongs to the Section Wearables)
31 pages, 4643 KiB  
Article
Hierarchical SVM for Semantic Segmentation of 3D Point Clouds for Infrastructure Scenes
by Mohamed Mansour, Jan Martens and Jörg Blankenbach
Infrastructures 2024, 9(5), 83; https://doi.org/10.3390/infrastructures9050083 (registering DOI) - 06 May 2024
Abstract
The incorporation of building information modeling (BIM) has brought about significant advancements in civil engineering, enhancing efficiency and sustainability across project life cycles. The utilization of advanced 3D point cloud technologies such as laser scanning extends the application of BIM, particularly in operations [...] Read more.
The incorporation of building information modeling (BIM) has brought about significant advancements in civil engineering, enhancing efficiency and sustainability across project life cycles. The utilization of advanced 3D point cloud technologies such as laser scanning extends the application of BIM, particularly in operations and maintenance, prompting the exploration of automated solutions for labor-intensive point cloud modeling. This paper presents a demonstration of supervised machine learning—specifically, a support vector machine—for the analysis and segmentation of 3D point clouds, which is a pivotal step in 3D modeling. The point cloud semantic segmentation workflow is extensively reviewed to encompass critical elements such as neighborhood selection, feature extraction, and feature selection, leading to the development of an optimized methodology for this process. Diverse strategies are implemented at each phase to enhance the overall workflow and ensure resilient results. The methodology is then evaluated using diverse datasets from infrastructure scenes of bridges and compared with state-of-the-art deep learning models. The findings highlight the effectiveness of supervised machine learning techniques at accurately segmenting 3D point clouds, outperforming deep learning models such as PointNet and PointNet++ with smaller training datasets. Through the implementation of advanced segmentation techniques, there is a partial reduction in the time required for 3D modeling of point clouds, thereby further enhancing the efficiency and effectiveness of the BIM process. Full article
47 pages, 3426 KiB  
Review
Recent Trends of Recycling and Upcycling of Polymers and Composites: A Comprehensive Review
by Christina Podara, Stefania Termine, Maria Modestou, Dionisis Semitekolos, Christos Tsirogiannis, Melpo Karamitrou, Aikaterini-Flora Trompeta, Tatjana Kosanovic Milickovic and Costas Charitidis
Recycling 2024, 9(3), 37; https://doi.org/10.3390/recycling9030037 (registering DOI) - 06 May 2024
Abstract
This review article gathers the most recent recycling technologies for thermoset and thermoplastic polymers. Results about existing experimental procedures and their effectiveness are presented. For thermoset polymers, the review focuses mainly on fibre-reinforced polymer composites, with an emphasis on epoxy-based systems and carbon/glass [...] Read more.
This review article gathers the most recent recycling technologies for thermoset and thermoplastic polymers. Results about existing experimental procedures and their effectiveness are presented. For thermoset polymers, the review focuses mainly on fibre-reinforced polymer composites, with an emphasis on epoxy-based systems and carbon/glass fibres as reinforcement, due to the environmental concerns of their end-of-life management. Thermal processes (fluidised bed, pyrolysis) and chemical processes (different types of solvolysis) are discussed. The most recent combined processes (microwave, steam, and ultrasonic assisted techniques) and extraordinary recycling attempts (electrochemical, biological, and with ionic liquids) are analysed. Mechanical recycling that leads to the downgrading of materials is excluded. Insights are also given for the upcycling methodologies that have been implemented until now for the reuse of fibres. As for thermoplastic polymers, the most state-of-the-art recycling approach for the most common polymer matrices is presented, together with the appropriate additivation for matrix upcycling. Mechanical, chemical, and enzymatic recycling processes are described, among others. The use of fibre-reinforced thermoplastic composites is quite new, and thus, the most recent achievements are presented. With all of the above information, this extensive review can serve as a guide for educational purposes, targeting students and technicians in polymers recycling. Full article
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15 pages, 433 KiB  
Review
Systemic Anti-Inflammatory Agents in the Prevention of Chemoradiation-Induced Mucositis: A Review of Randomised Controlled Trials
by Ali I. Mohammed, Lexi Fedoruk, Nicholas Fisher, Andy Xiaoqian Liu, Samar Khanna, Kaelan Naylor, Ziyi Gong, Antonio Celentano, Mohammad S. Alrashdan and Nicola Cirillo
Biomolecules 2024, 14(5), 560; https://doi.org/10.3390/biom14050560 (registering DOI) - 06 May 2024
Abstract
Mucositis is a pathological condition characterised by inflammation and ulceration of the mucous membranes lining the alimentary canal, particularly in the mouth (oral mucositis) and the gastrointestinal tract. It is a common side effect of cancer treatments, including chemotherapy and radiotherapy, and it [...] Read more.
Mucositis is a pathological condition characterised by inflammation and ulceration of the mucous membranes lining the alimentary canal, particularly in the mouth (oral mucositis) and the gastrointestinal tract. It is a common side effect of cancer treatments, including chemotherapy and radiotherapy, and it is sometimes responsible for treatment interruptions. Preventing mucositis throughout the alimentary tract is therefore crucial. However, current interventions mainly target either oral or gastrointestinal side effects. This review aimed to investigate the use of systemically administered anti-inflammatory agents to prevent mucositis in cancer patients undergoing cancer treatment. PubMed, Ovid, Scopus, Web of Science, WHO ICTRP and ClinicalTrials.gov were screened to identify eligible randomised controlled trials (RCTs). The published literature on anti-inflammatory agents provides mixed evidence regarding the degree of efficacy in preventing/reducing the severity of mucositis in most anticancer treatments; however, sample size continued to be a significant limitation, alongside others discussed. Our review yielded a list of several anti-inflammatory agents that exhibit potential mucositis-preventive effects in cancer patients undergoing cancer treatment, which can be used to inform clinical practice. Full article
14 pages, 4019 KiB  
Article
Performance of API Design for Interoperability of Medical Information Systems
by Leticia Dávila Nicanor, Abraham Banda Madrid, Jesús E. Martínez Hernández and Irene Aguilar Juárez
Appl. Sci. 2024, 14(9), 3944; https://doi.org/10.3390/app14093944 (registering DOI) - 06 May 2024
Abstract
After the experience of the COVID-19 pandemic, it has become evident that efficient and secure interoperability of medical information is crucial for effective diagnoses and medical treatments. However, a significant challenge arises concerning the heterogeneity of the systems storing patient information in medical [...] Read more.
After the experience of the COVID-19 pandemic, it has become evident that efficient and secure interoperability of medical information is crucial for effective diagnoses and medical treatments. However, a significant challenge arises concerning the heterogeneity of the systems storing patient information in medical centers or hospitals. Memory management becomes a pivotal element for the effective operation of the proposed API, as it must seamlessly execute across various devices, ranging from healthcare units, such as mobile phones, to servers in cloud computing. This proposal addresses these issues through techniques designed to enhance the performance of the software architecture in creating a medical interoperability API. This API has the capacity to be cloned and distributed to facilitate the exchange of data related to a patient’s medical history. To tackle heterogeneity, efficient memory management was implemented by utilizing an object-oriented approach and leveraging design patterns like abstract factory and wrapper. Regarding the evaluation of the proposal, this study showed an estimated performance of 94.5 percent, which was indirectly demonstrated through the assessment of operation sequences. This result suggests a satisfactory level based on complexity and coupling. Full article
(This article belongs to the Special Issue Smart Systems in Medical Informatics)
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12 pages, 674 KiB  
Article
Coronary Computed Tomography Angiography-Derived Modified Duke Index Is Associated with Peri-Coronary Fat Attenuation Index and Predicts Severity of Coronary Inflammation
by Vasile-Bogdan Halațiu, Imre Benedek, Ioana-Patricia Rodean, Liliana-Oana Cojocariu, Theofana Mihăilă, Emanuel Blîndu, Aurelian Roșca, Botond-Barna Mátyás, Renata Gerculy, Florin Buicu and Theodora Benedek
Medicina 2024, 60(5), 765; https://doi.org/10.3390/medicina60050765 (registering DOI) - 06 May 2024
Abstract
Background and Objectives: The modified Duke index derived from coronary computed tomography angiography (CCTA) was designed to predict cardiovascular outcomes based on the severity of coronary stenosis. However, it does not take into consideration the presence or severity of peri‑coronary inflammation. The [...] Read more.
Background and Objectives: The modified Duke index derived from coronary computed tomography angiography (CCTA) was designed to predict cardiovascular outcomes based on the severity of coronary stenosis. However, it does not take into consideration the presence or severity of peri‑coronary inflammation. The peri-coronary fat attenuation index (FAI) is a novel imaging marker determined by CCTA which reflects the degree of inflammation in the coronary tree in patients with coronary artery disease. To assess the association between the modified Duke index assessed by CCTA, cardiovascular risk factors, and peri-coronary inflammation in the coronary arteries of patients with coronary artery disease. Materials and Methods: One hundred seventy-two patients who underwent CCTA for typical angina were assigned into two groups based on the modified Duke index: group 1—patients with low index, ≤3 (n = 107), and group 2—patients with high index, >3 (n = 65). Demographic, clinical, and CCTA data were collected for all patients, and FAI analysis of coronary inflammation was performed. Results: Patients with increased values of the modified Duke index were significantly older compared to those with a low index (61.83 ± 9.89 vs. 64.78 ± 8.9; p = 0.002). No differences were found between the two groups in terms of gender distribution, hypertension, hypercholesterolemia, or smoking history (all p > 0.5). The FAI score was significantly higher in patients from group 2, who presented a significantly higher score of inflammation compared to the patients in group 1, especially at the level of the right coronary artery (FAI score, 20.85 ± 15.80 vs. 14.61 ± 16.66; p = 0.01 for the right coronary artery, 13.85 ± 8.04 vs. 10.91 ± 6.5; p = 0.01 for the circumflex artery, 13.26 ± 10.18 vs. 11.37 ± 8.84; p = 0.2 for the left anterior descending artery). CaRi-Heart® analysis identified a significantly higher risk of future events among patients with a high modified Duke index (34.84% ± 25.86% vs. 16.87% ± 15.80%; p < 0.0001). ROC analysis identified a cut-off value of 12.1% of the CaRi-Heart® risk score for predicting a high severity of coronary lesions, with an AUC of 0.69. Conclusions: The CT-derived modified Duke index correlates well with local perilesional inflammation as assessed using the FAI score at different levels of the coronary circulation. Full article
(This article belongs to the Section Cardiology)
11 pages, 1118 KiB  
Article
Prospective Analysis of Squamous Cell Carcinoma Antigen-1 and -2 for Diagnosing Sinonasal Inverted Papilloma
by Hitoshi Hirakawa, Taro Ikegami, Masatomo Toyama, Yurika Ooshiro, Tomoyo Higa, Hidetoshi Kinjyo, Shunsuke Kondo, Norimoto Kise, Yukashi Yamashita and Mikio Suzuki
J. Clin. Med. 2024, 13(9), 2721; https://doi.org/10.3390/jcm13092721 (registering DOI) - 06 May 2024
Abstract
Background: The goal of this research was to confirm whether preoperative serum squamous cell carcinoma antigen (SCCA)-1 and -2 levels are useful diagnostic markers for sinonasal inverted papilloma (IP) in a prospective study. Methods: Participants were 102 patients who underwent consecutive [...] Read more.
Background: The goal of this research was to confirm whether preoperative serum squamous cell carcinoma antigen (SCCA)-1 and -2 levels are useful diagnostic markers for sinonasal inverted papilloma (IP) in a prospective study. Methods: Participants were 102 patients who underwent consecutive endoscopic sinus surgery: 18 with IP, two with other types of papilloma, 77 with chronic rhinosinusitis, four with sinonasal cancer, and one with hemangioma. SCCA-1 and SCCA-2 were measured preoperatively by an automatic chemiluminescence immunoassay and an enzyme-linked immunosorbent assay, respectively. Results: SCCA-1 and SCCA-2 values were significantly correlated (r = 0.603, p < 0.001). Receiver operating characteristic analysis for differentiating papilloma (IP and other types of papilloma) from other diseases yielded an area under the curve of 0.860, with a Youden index of 1.75. Combined with SCCA-2 analysis, the detection system had a sensitivity and specificity of 0.65 and 0.98, respectively. While our study did not find a strong link between SCCA levels and skin or lung diseases, smoking status may influence SCCA levels in IP patients (p = 0.035). We recommend a cutoff value of 1.8 ng/mL for SCCA-1 in IP diagnosis. Conclusions: SCCA-1 and SCCA-2 when combined with imaging and pathology hold promise for enhancing the preoperative detection of IP, which would be a valuable contribution to clinical practice. Full article
(This article belongs to the Section Otolaryngology)
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20 pages, 4634 KiB  
Article
Spatial Spillover Effects of Urbanization on Ecosystem Services under Altitude Gradient
by Xueliang Yang, Kaiping Wang and Yunlu Zhang
Land 2024, 13(5), 622; https://doi.org/10.3390/land13050622 (registering DOI) - 06 May 2024
Abstract
Rapid urbanization has made mountain development an important means to alleviate the shortages of construction land on plains, which has significantly affected regional ecosystem services. In-depth research on the impact of urbanization on ecosystem services under altitude gradients is of great significance to [...] Read more.
Rapid urbanization has made mountain development an important means to alleviate the shortages of construction land on plains, which has significantly affected regional ecosystem services. In-depth research on the impact of urbanization on ecosystem services under altitude gradients is of great significance to clarify the relationship between the two. Based on data from 2000, 2010 and 2020, the urbanization level and ecosystem services of the study area were evaluated. The spatial correlation of ecosystem services was analyzed by Moran’s I. A spatial Durbin model (SDM) was selected to fit the regression. The results show that (1) from 2000 to 2020, the ecosystem services in the study area displayed obvious regional characteristics and aggregation characteristics; (2) in plain areas, the indirect effects of economic, population and land urbanization have a greater negative impact, and compared with shallow mountain areas, deep mountain areas are more negatively affected by economic urbanization and land urbanization; and (3) the significant difference in regression results reflects the rationality of using the spatial Durbin model, as in this paper, and proves the scientific nature of regional coordinated development. The research results provide a reference for the future coordinated development of regional economies and environments. Full article
16 pages, 5880 KiB  
Article
Rust Prevention Property of a New Organic Inhibitor under Different Conditions
by Xingxing Guo, Chengsheng Wang, Hua Fu, Li Tian and Hua Song
Materials 2024, 17(9), 2168; https://doi.org/10.3390/ma17092168 (registering DOI) - 06 May 2024
Abstract
The corrosion resistance properties of a new type of environmentally-friendly organic inhibitor containing amino ketone molecules are presented in this paper. To evaluate the prevention effect of the inhibitor on corrosion of reinforcement, the electrochemical characteristics of steels in the simulated concrete pore [...] Read more.
The corrosion resistance properties of a new type of environmentally-friendly organic inhibitor containing amino ketone molecules are presented in this paper. To evaluate the prevention effect of the inhibitor on corrosion of reinforcement, the electrochemical characteristics of steels in the simulated concrete pore solution (SPS) were investigated under varied conditions of the relevant parameters, including concentrations of the inhibitor and NaCl, pH value, and temperature. The inhibition efficiency of the material was characterized through electrochemical impedance spectroscopy (EIS), potentiodynamic polarization, and the weight loss of steels. The results reveal a significant improvement in the corrosion resistance of steels with the inhibitor. A maximum resistance value of 89.07% was achieved at an inhibitor concentration of 4%. Moreover, the new organic inhibitor exhibited good corrosion protection capability for steels under different NaCl concentrations. Its inhibition efficiency was determined to be 65.62, 80.06, and 66.30% at NaCl concentrations of 2, 3.5 and 5%, respectively. On the other hand, it was found that an alkaline environment was favorable for an enhanced corrosion prevention effect, and an optimal pH value of 11.3 was observed in this work. Besides, the inhibition efficiencies at different temperatures showed a trend of 25 > 35 > 40 > 20 > 30 °C, with a maximum value of 81.32% at 25 °C. The above results suggest that the new organic material has high potential to be used as an eco-friendly and long-term durable inhibitor for steel corrosion prevention under complex conditions. Full article
(This article belongs to the Special Issue Corrosion Mechanism and Protection Technology of Metallic Materials)
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15 pages, 4413 KiB  
Article
Preparation of Hydrophilic and Fire-Resistant Phytic Acid/Chitosan/Polydopamine-Coated Expanded Polystyrene Particles by Using Coating Method
by Wenjie Tang, Dajian Huang, Xiaohu Qiang and Wang Liu
Coatings 2024, 14(5), 574; https://doi.org/10.3390/coatings14050574 (registering DOI) - 06 May 2024
Abstract
Expanded polystyrene (EPS) particles are commonly used for thermal insulation in lightweight building materials due to their low density, low thermal conductivity, and affordability. However, shortcomings such as hydrophobicity and poor fire safety limit the application of EPS. Bio-based flame retardants have been [...] Read more.
Expanded polystyrene (EPS) particles are commonly used for thermal insulation in lightweight building materials due to their low density, low thermal conductivity, and affordability. However, shortcomings such as hydrophobicity and poor fire safety limit the application of EPS. Bio-based flame retardants have been developed for use in polymer composites due to their renewable, environmentally friendly, and non-toxic properties. In this study, to improve the hydrophilicity and fire resistance of EPS particles, phytic acid (PA)/chitosan (CS)–polydopamine (PDA)@EPS particles (PA/CS-PDA@EPS) with a bio-based coating were prepared by using a simple coating method based on PDA@EPS particles using PDA as an adhesive and PA and CS as bio-based flame retardants. The results showed that the modified EPS particles had good hydrophilicity, the residual carbon yield of the 10PA/3CS-PDA@EPS samples was increased to 24 wt%, and the maximum loss rate was reduced by 69% compared with unmodified EPS. In flammability tests, the 10PA/3CS-PDA@EPS samples also demonstrated low flame spread and some fire resistance. Furthermore, the modified EPS particles exhibited fire resistance even after multiple washings. The hydrophilic and fire-resistant modified EPS particles are anticipated to offer a novel approach to the advancement of EPS-based lightweight building materials. Full article
(This article belongs to the Special Issue Surface Modification and Coating Techniques for Polymers)
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14 pages, 2922 KiB  
Article
A Study on the Materials Used in Ancient Wooden Architectural Paintings at DaZhong Gate in Confucius Temple, Qufu, Shandong, China
by Kuiju Li, Kezhu Han, Gele Teri, Yuxiao Tian, Menglei Cui, Yunpeng Qi and Yuhu Li
Materials 2024, 17(9), 2170; https://doi.org/10.3390/ma17092170 (registering DOI) - 06 May 2024
Abstract
This study analyzes the pigments and binders used in the painted wooden structure of DaZhong Gate in the Confucius Temple in Qufu, Shandong Province, China. Five samples were collected from the building and analyzed using techniques such as polarized light microscopy (PLM), energy-dispersive [...] Read more.
This study analyzes the pigments and binders used in the painted wooden structure of DaZhong Gate in the Confucius Temple in Qufu, Shandong Province, China. Five samples were collected from the building and analyzed using techniques such as polarized light microscopy (PLM), energy-dispersive X-ray spectroscopy (EDX), micro-Raman spectroscopy (m-RS), and Fourier-transform infrared spectroscopy (FT-IR). The findings reveal that the red, yellow, green, and blue pigments are identified as lead red, lead chromate yellow, emerald green, and ultramarine, respectively. The white pigment is determined to be a combination of chalk and lead white or anglesite. Considering the production period of the yellow and green pigments, it is inferred that architectural paintings underwent restoration or repainting during the late Qing Dynasty. The analysis of the binder in the pigment using pyrolysis–gas chromatography/mass spectrometry (Py-GC/MS) reveals that the binder employed is a protein-based glue. Additionally, the detected presence of Heat-bodied tung oil suggests a potential connection to traditional Chinese painting techniques on wooden surfaces. This discovery not only contributes to the historical research of the Confucius Temple but also provides crucial data for the conservation and restoration efforts of this culturally significant heritage site. Full article
(This article belongs to the Topic Advances in Non-Destructive Testing Methods, 2nd Volume)
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18 pages, 2487 KiB  
Review
Electron Transfer in the Biogeochemical Sulfur Cycle
by Xuliang Zhuang, Shijie Wang and Shanghua Wu
Life 2024, 14(5), 591; https://doi.org/10.3390/life14050591 (registering DOI) - 06 May 2024
Abstract
Microorganisms are key players in the global biogeochemical sulfur cycle. Among them, some have garnered particular attention due to their electrical activity and ability to perform extracellular electron transfer. A growing body of research has highlighted their extensive phylogenetic and metabolic diversity, revealing [...] Read more.
Microorganisms are key players in the global biogeochemical sulfur cycle. Among them, some have garnered particular attention due to their electrical activity and ability to perform extracellular electron transfer. A growing body of research has highlighted their extensive phylogenetic and metabolic diversity, revealing their crucial roles in ecological processes. In this review, we delve into the electron transfer process between sulfate-reducing bacteria and anaerobic alkane-oxidizing archaea, which facilitates growth within syntrophic communities. Furthermore, we review the phenomenon of long-distance electron transfer and potential extracellular electron transfer in multicellular filamentous sulfur-oxidizing bacteria. These bacteria, with their vast application prospects and ecological significance, play a pivotal role in various ecological processes. Subsequently, we discuss the important role of the pili/cytochrome for electron transfer and presented cutting-edge approaches for exploring and studying electroactive microorganisms. This review provides a comprehensive overview of electroactive microorganisms participating in the biogeochemical sulfur cycle. By examining their electron transfer mechanisms, and the potential ecological and applied implications, we offer novel insights into microbial sulfur metabolism, thereby advancing applications in the development of sustainable bioelectronics materials and bioremediation technologies. Full article
(This article belongs to the Special Issue Advances in the Structure and Function of Microbial Communities)
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18 pages, 1293 KiB  
Review
Sacral Bioneuromodulation: The Role of Bone Marrow Aspirate in Spinal Cord Injuries
by José Fábio Lana, Annu Navani, Madhan Jeyaraman, Napoliane Santos, Luyddy Pires, Gabriel Silva Santos, Izair Jefthé Rodrigues, Douglas Santos, Tomas Mosaner, Gabriel Azzini, Lucas Furtado da Fonseca, Alex Pontes de Macedo, Stephany Cares Huber, Daniel de Moraes Ferreira Jorge and Joseph Purita
Bioengineering 2024, 11(5), 461; https://doi.org/10.3390/bioengineering11050461 (registering DOI) - 06 May 2024
Abstract
Spinal cord injury (SCI) represents a severe trauma to the nervous system, leading to significant neurological damage, chronic inflammation, and persistent neuropathic pain. Current treatments, including pharmacotherapy, immobilization, physical therapy, and surgical interventions, often fall short in fully addressing the underlying pathophysiology and [...] Read more.
Spinal cord injury (SCI) represents a severe trauma to the nervous system, leading to significant neurological damage, chronic inflammation, and persistent neuropathic pain. Current treatments, including pharmacotherapy, immobilization, physical therapy, and surgical interventions, often fall short in fully addressing the underlying pathophysiology and resultant disabilities. Emerging research in the field of regenerative medicine has introduced innovative approaches such as autologous orthobiologic therapies, with bone marrow aspirate (BMA) being particularly notable for its regenerative and anti-inflammatory properties. This review focuses on the potential of BMA to modulate inflammatory pathways, enhance tissue regeneration, and restore neurological function disrupted by SCI. We hypothesize that BMA’s bioactive components may stimulate reparative processes at the cellular level, particularly when applied at strategic sites like the sacral hiatus to influence lumbar centers and higher neurological structures. By exploring the mechanisms through which BMA influences spinal repair, this review aims to establish a foundation for its application in clinical settings, potentially offering a transformative approach to SCI management that extends beyond symptomatic relief to promoting functional recovery. Full article
(This article belongs to the Special Issue Innovations in Nerve Regeneration)
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