The 2023 MDPI Annual Report has
been released!
 
14 pages, 1088 KiB  
Article
Association between COVID-19 Booster Vaccination and COVID-19 Outcomes among U.S. Adults
by Kimberly H. Nguyen, Cheyenne McChesney, Ruchi Patel, Robert A. Bednarczyk, Lavanya Vasudevan and Laura Corlin
Vaccines 2024, 12(5), 503; https://doi.org/10.3390/vaccines12050503 (registering DOI) - 07 May 2024
Abstract
Understanding the association between booster vaccination and COVID-19 outcomes can help strengthen post-pandemic messaging and strategies to increase vaccination and reduce severe and long-term consequences of COVID-19. Using the Household Pulse Survey data collected from U.S. adults from 9 December 2022 to 13 [...] Read more.
Understanding the association between booster vaccination and COVID-19 outcomes can help strengthen post-pandemic messaging and strategies to increase vaccination and reduce severe and long-term consequences of COVID-19. Using the Household Pulse Survey data collected from U.S. adults from 9 December 2022 to 13 February 2023 (n = 214,768), this study assessed the relationship between COVID-19 booster vaccination and COVID-19 outcomes (testing positive for COVID-19, moderate/severe COVID-19, and long COVID). Disparities were found in COVID-19 outcomes (e.g., testing positive for COVID-19, moderate/severe COVID-19, and long COVID) by sociodemographic characteristics, region of residence, food insecurity status, mental health status, disability status, and housing type. Receipt of a COVID-19 booster vaccination was negatively associated with testing positive for COVID-19 (aOR = 0.75, 95%CI: 0.72,0.79), having moderate/severe COVID-19 (aOR = 0.92, 95%CI: 0.88, 0.97), or having long COVID (aOR = 0.86 (0.80, 0.91)). Even among those who tested positive for COVID-19, those who received the booster vaccine were less likely to have moderate/severe COVID-19 and less likely to have long COVID. Communicating the benefits of COVID-19 booster vaccination, integrating vaccination in patient visits, and reducing access barriers can increase vaccination uptake and confidence for all individuals and protect them against the severe negative outcomes of COVID-19. Full article
(This article belongs to the Special Issue Vaccines and Vaccinations in the Pandemic Period)
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32 pages, 1244 KiB  
Review
A Narrative Review of the Sociotechnical Landscape and Potential of Computer-Assisted Dynamic Assessment for Children with Communication Support Needs
by Christopher S. Norrie, Stijn R. J. M. Deckers, Maartje Radstaake and Hans van Balkom
Multimodal Technol. Interact. 2024, 8(5), 38; https://doi.org/10.3390/mti8050038 (registering DOI) - 07 May 2024
Abstract
This paper presents a narrative review of the current practices in assessing learners’ cognitive abilities and the limitations of traditional intelligence tests in capturing a comprehensive understanding of a child’s learning potential. Referencing prior research, it explores the concept of dynamic assessment (DA) [...] Read more.
This paper presents a narrative review of the current practices in assessing learners’ cognitive abilities and the limitations of traditional intelligence tests in capturing a comprehensive understanding of a child’s learning potential. Referencing prior research, it explores the concept of dynamic assessment (DA) as a promising yet underutilised alternative that focuses on a child’s responsiveness to learning opportunities. The paper highlights the potential of novel technologies, in particular tangible user interfaces (TUIs), in integrating computational science with DA to improve the access and accuracy of assessment results, especially for children with communication support needs (CSN), as a catalyst for abetting critical communicative competencies. However, existing research in this area has mainly focused on the automated mediation of DA, neglecting the human element that is crucial for effective solutions in special education. A framework is proposed to address these issues, combining pedagogical and sociocultural elements alongside adaptive information technology solutions in an assessment system informed by user-centred design principles to fully support teachers/facilitators and learners with CSN within the special education ecosystem. Full article
29 pages, 587 KiB  
Review
Bioavailability of Anthocyanins: Whole Foods versus Extracts
by Ravish Kumkum, Kathryn Aston-Mourney, Bryony A. McNeill, Damián Hernández and Leni R. Rivera
Nutrients 2024, 16(10), 1403; https://doi.org/10.3390/nu16101403 (registering DOI) - 07 May 2024
Abstract
Anthocyanins have gained significant popularity in recent years for their diverse health benefits, yet their limited bioavailability poses a challenge. To address this concern, technologies have emerged to enhance anthocyanin concentration, often isolating these compounds from other food constituents. However, the extent to [...] Read more.
Anthocyanins have gained significant popularity in recent years for their diverse health benefits, yet their limited bioavailability poses a challenge. To address this concern, technologies have emerged to enhance anthocyanin concentration, often isolating these compounds from other food constituents. However, the extent to which isolated anthocyanins confer health benefits compared to their whole-food counterparts remains unclear. This review explores the current literature on anthocyanin bioavailability and metabolism in the body, with a focus on comparing bioavailability when consumed as extracts versus whole foods rich in anthocyanins, drawing from in vitro, in vivo, and human clinical studies. While direct comparisons between anthocyanin bioavailability in whole foods versus isolates are scarce, prevailing evidence favours whole-food consumption over anthocyanin extracts. Further clinical investigations, preferably with direct comparisons, are needed to validate these findings and elucidate the nuanced interplay between anthocyanins and food matrices, informing future research directions and practical recommendations. Full article
(This article belongs to the Section Phytochemicals and Human Health)
19 pages, 4466 KiB  
Article
Detection of Korean Phishing Messages Using Biased Discriminant Analysis under Extreme Class Imbalance Problem
by Siyoon Kim, Jeongmin Park, Hyun Ahn and Yonggeol Lee
Information 2024, 15(5), 265; https://doi.org/10.3390/info15050265 (registering DOI) - 07 May 2024
Abstract
In South Korea, the rapid proliferation of smartphones has led to an uptick in messenger phishing attacks associated with electronic communication financial scams. In response to this, various phishing detection algorithms have been proposed. However, collecting messenger phishing data poses challenges due to [...] Read more.
In South Korea, the rapid proliferation of smartphones has led to an uptick in messenger phishing attacks associated with electronic communication financial scams. In response to this, various phishing detection algorithms have been proposed. However, collecting messenger phishing data poses challenges due to concerns about its potential use in criminal activities. Consequently, a Korean phishing dataset can be composed of imbalanced data, where the number of general messages might outnumber the phishing ones. This class imbalance problem and data scarcity can lead to overfitting issues, making it difficult to achieve high performance. To solve this problem, this paper proposes a phishing messages classification method using Biased Discriminant Analysis without resorting to data augmentation techniques. In this paper, by optimizing the parameters for BDA, we achieved exceptionally high performances in the phishing messages classification experiment, with 95.45% for Recall and 96.85% for the BA metric. Moreover, when compared with other algorithms, the proposed method demonstrated robustness against overfitting due to the class imbalance problem and exhibited minimal performance disparity between training and testing datasets. Full article
13 pages, 1349 KiB  
Article
Novel Ferrocene-Containing Triacyl Derivative of Resveratrol Protects Ovarian Cells from Toxicity Caused by Ortho-Substituted Polychlorinated Biphenyls
by Ivana Kmetič, Teuta Murati, Veronika Kovač, Lidija Barišić, Nina Bilandžić, Branimir Šimić and Marina Miletić
Processes 2024, 12(5), 947; https://doi.org/10.3390/pr12050947 (registering DOI) - 07 May 2024
Abstract
Polychlorinated biphenyls (PCBs) can induce neurotoxicity, immunotoxicity, reproductive toxicity, genotoxicity, and carcinogenicity (IARC group 1 Carcinogens). Scientific data suggest that resveratrol possesses the ability to attenuate ortho-PCB-induced toxicity. Recently, a novel ferrocene-containing triacyl derivative of resveratrol (RF) was synthesized and in this [...] Read more.
Polychlorinated biphenyls (PCBs) can induce neurotoxicity, immunotoxicity, reproductive toxicity, genotoxicity, and carcinogenicity (IARC group 1 Carcinogens). Scientific data suggest that resveratrol possesses the ability to attenuate ortho-PCB-induced toxicity. Recently, a novel ferrocene-containing triacyl derivative of resveratrol (RF) was synthesized and in this study, its potential to protect CHO-K1 cells from selected PCB congeners (75 µM) was evaluated. Cell viability/proliferation was observed by Trypan Blue (TB), Neutral Red (NR), Kenacid Blue (KB), and MTT bioassays, ROS formation by fluorescent probes, and the extent of apoptosis by flow cytometry. All applied bioassays confirmed that RF (2.5–100 μM) remarkably improves viability in PCB 153-treated cells with an increase in cell survival almost up to control levels. This effect was not determined after PCB 77 exposure, although ROS formation was decreased at RF ≥ 50 µM. Apoptosis was significant (p < 0.05) for both congeners. In PCB 77-treated cells, RF did not suppress the induction of cell death. The intended protective effect of RF was evident when cells were treated with PCB 153, and this correlates with results obtained for cell viability. Compared to resveratrol, the novel RF showed promising results in terms of improved biological activity and cell protection against PCB 153 toxicity at all concentrations tested. Full article
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24 pages, 4034 KiB  
Article
DFT-D3 and TD-DFT Studies of the Adsorption and Sensing Behavior of Mn-Phthalocyanine toward NH3, PH3, and AsH3 Molecules
by Heba Mohamed Badran, Khaled Mahmoud Eid, Hatim Omar Al-Nadary and Hussein Youssef Ammar
Molecules 2024, 29(10), 2168; https://doi.org/10.3390/molecules29102168 (registering DOI) - 07 May 2024
Abstract
This study employs density functional theory (DFT) calculations at the B3LYP/6-311+g(d,p) level to investigate the interaction of XH3 gases (X = N, P, As) with the Mn-phthalocyanine molecule (MnPc). Grimme’s D3 dispersion correction is applied to consider long-range interactions. The adsorption behavior [...] Read more.
This study employs density functional theory (DFT) calculations at the B3LYP/6-311+g(d,p) level to investigate the interaction of XH3 gases (X = N, P, As) with the Mn-phthalocyanine molecule (MnPc). Grimme’s D3 dispersion correction is applied to consider long-range interactions. The adsorption behavior is explored under the influence of an external static electric field (EF) ranging from −0.514 to 0.514 V/Å. Chemical adsorption of XH3 molecules onto the MnPc molecule is confirmed. The adsorption results in a significant decrease in the energy gap (Eg) of MnPc, indicating the potential alteration of its optical properties. Quantum theory of atoms in molecules (QTAIM) analysis reveals partially covalent bonds between XH3 and MnPc, and the charge density differenc (Δρ) calculations suggest a charge donation-back donation mechanism. The UV-vis spectrum of MnPc experiences a blue shift upon XH3 adsorption, highlighting MnPc’s potential as a naked-eye sensor for XH3 molecules. Thermodynamic calculations indicate exothermic interactions, with NH3/MnPc being the most stable complex. The stability of NH3/MnPc decreases with increasing temperature. The direction and magnitude of the applied electric field (EF) play a crucial role in determining the adsorption energy (Eads) for XH3/MnPc complexes. The Eg values decrease with an increasing negative EF, which suggests that the electrical conductivity (σ) and the electrical sensitivity (ΔEg) of the XH3/MnPc complexes are influenced by the magnitude and direction of the applied EF. Overall, this study provides valuable insights into the suggested promising prospects for the utilization of MnPc in sensing applications of XH3 gases. Full article
(This article belongs to the Section Computational and Theoretical Chemistry)
25 pages, 2137 KiB  
Article
Role of Semiconductive Property on Selective Cementation Mechanism of Iron Oxides to Gold in Galvanic Interaction with Zero-Valent Aluminum from Gold–Copper Ammoniacal Thiosulfate Solutions
by Joshua Zoleta, Kosei Aikawa, Nako Okada, Ilhwan Park, Mayumi Ito, Yogarajah Elakneswaran and Naoki Hiroyoshi
Metals 2024, 14(5), 550; https://doi.org/10.3390/met14050550 (registering DOI) - 07 May 2024
Abstract
Iron oxides (hematite, Fe2O3, and magnetite, Fe3O4), previously used as electron mediators in the galvanic system with zero-valent aluminum (ZVAl), have been shown to recover Au upon cementation in Au–Cu ammoniacal thiosulfate media selectively, and [...] Read more.
Iron oxides (hematite, Fe2O3, and magnetite, Fe3O4), previously used as electron mediators in the galvanic system with zero-valent aluminum (ZVAl), have been shown to recover Au upon cementation in Au–Cu ammoniacal thiosulfate media selectively, and this warrants further investigation. This research is focused on investigating the role of the semiconductive properties of metal oxides by performing a cementation experiment by mixing 0.15 g of electron mediators (Fe3O4, Fe2O3, TiO2 (anatase and rutile)) and 0.15 g of zero-valent aluminum powder as an electron donor in various electrochemical experiments. The results revealed that upon the cementation experiment, synthetic Fe2O3 and Fe3O4 were consistently able to selectively recover Au at around 90% and Cu at around 20%. Compared to activated carbon (AC), TiO2, in anatase and rutile forms, obtained selective recovery of gold, but the recovery was utterly insignificant compared to that of iron oxides, obtaining an average of 93% Au and 63% Cu recovery. The electrochemical and surface analysis supports the results obtained upon the cementation process, where TiO2, upon cyclic voltammetry (CV), obtained two reduction peaks centered at −1.0 V and −0.5 V assigned to reducing Au and Cu ions, respectively. Furthermore, various electrochemical impedance spectroscopic analyses revealed that the flat band potential obtained in the Mott–Schottky plot is around −1.0 V and −0.2 V for iron oxides and titanium oxides, respectively, suggesting that the electrons travel from semiconductor interface to electrolyte interface, and electrons are accessible only to Au ions in the electrolyte interface (reduction band edge around −1.0 V). The determination of this selective cementation mechanism is one of a kind. It has been proposed that the semiconductive properties of Fe2O3, Fe3O4, and, by configuring their relative energy band diagram, the travel of electrons from the iron oxide–electrolyte interface facilitate the selective cementation towards Au(S2O3)23+ ions in gold–copper ammoniacal thiosulfate solutions. Full article
(This article belongs to the Section Extractive Metallurgy)
12 pages, 2017 KiB  
Article
Cross-Water–Air Optical Wireless Communication Using Orthogonal Time–Frequency Space Modulation
by Dianbin Lian, Yan Gao and Jie Lian
Symmetry 2024, 16(5), 571; https://doi.org/10.3390/sym16050571 (registering DOI) - 07 May 2024
Abstract
This paper examines the communication difficulties encountered in cross-media wireless optical transmission through simulated research on the utilization of orthogonal time and frequency space (OTFS) modulation technology. Our analysis and comparison demonstrate that OTFS significantly improves the reliability and throughput of data transmission [...] Read more.
This paper examines the communication difficulties encountered in cross-media wireless optical transmission through simulated research on the utilization of orthogonal time and frequency space (OTFS) modulation technology. Our analysis and comparison demonstrate that OTFS significantly improves the reliability and throughput of data transmission in intricate multipath channel settings. In contrast to conventional orthogonal frequency division multiplexing (OFDM) technology, OTFS displays better resilience and transmission effectiveness. We foresee additional enhancements and progress in OTFS technology to present a sturdier and more efficient resolution for wireless communication, thereby providing valuable perspectives and encouragement for associated research initiatives. Our results underscore the capability of OTFS technology to transform wireless communication systems in demanding multipath channel conditions. Full article
(This article belongs to the Special Issue Symmetry and Its Application in Wireless Communication)
19 pages, 3639 KiB  
Article
Effects of Mactra chinenesis Peptides on Alcohol-Induced Acute Liver Injury and Intestinal Flora in Mice
by Dong Wu, Ming Cheng, Xiangzhou Yi, Guanghua Xia, Zhongyuan Liu, Haohao Shi and Xuanri Shen
Foods 2024, 13(10), 1431; https://doi.org/10.3390/foods13101431 (registering DOI) - 07 May 2024
Abstract
Food-borne bioactive peptides have shown promise in preventing and mitigating alcohol-induced liver injury. This study was the first to assess the novel properties of Mactra chinenesis peptides (MCPs) in mitigating acute alcoholic liver injury in mice, and further elucidated the underlying mechanisms associated [...] Read more.
Food-borne bioactive peptides have shown promise in preventing and mitigating alcohol-induced liver injury. This study was the first to assess the novel properties of Mactra chinenesis peptides (MCPs) in mitigating acute alcoholic liver injury in mice, and further elucidated the underlying mechanisms associated with this effect. The results showed that MCPs can improve lipid metabolism by modulating the AMPK signaling pathway, decreasing fatty acid synthase activity, and increasing carnitine palmitoyltransferase 1a activity. Meanwhile, MCPs ameliorate inflammation by inhibiting the NF-κB activation, leading to reduced levels of pro-inflammatory cytokines (tumor necrosis factor-α and interleukin-1β). Additionally, a 16S rDNA sequencing analysis revealed that MCPs can restore the balance of gut microbiota and increase the relative abundance of beneficial bacteria. These findings suggest that supplementation of MCPs could attenuate alcohol intake-induced acute liver injury, and, thus, may be utilized as a functional dietary supplement for the successful treatment and prevention of acute liver injury. Full article
(This article belongs to the Section Nutraceuticals, Functional Foods, and Novel Foods)
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17 pages, 4881 KiB  
Article
Intelligent Packet Priority Module for a Network of Unmanned Aerial Vehicles Using Manhattan Long Short-Term Memory
by Dino Budi Prakoso, Jauzak Hussaini Windiatmaja, Agus Mulyanto, Riri Fitri Sari and Rosdiadee Nordin
Drones 2024, 8(5), 183; https://doi.org/10.3390/drones8050183 (registering DOI) - 07 May 2024
Abstract
Unmanned aerial vehicles (UAVs) are becoming more common in wireless communication networks. Using UAVs can lead to network problems. An issue arises when the UAVs function in a network-access-limited environment with nodes causing interference. This issue could potentially hinder UAV network connectivity. This [...] Read more.
Unmanned aerial vehicles (UAVs) are becoming more common in wireless communication networks. Using UAVs can lead to network problems. An issue arises when the UAVs function in a network-access-limited environment with nodes causing interference. This issue could potentially hinder UAV network connectivity. This paper introduces an intelligent packet priority module (IPPM) to minimize network latency. This study analyzed Network Simulator–3 (NS-3) network modules utilizing Manhattan long short-term memory (MaLSTM) for packet classification of critical UAV, ground control station (GCS), or interfering nodes. To minimize network latency and packet delivery ratio (PDR) issues caused by interfering nodes, packets from prioritized nodes are transmitted first. Simulation results and evaluation show that our proposed intelligent packet priority module (IPPM) method outperformed previous approaches. The proposed IPPM based on MaLSTM implementation for the priority packet module led to a lower network delay and a higher packet delivery ratio. The performance of the IPPM averaged 62.2 ms network delay and 0.97 packet delivery ratio (PDR). The MaLSTM peaked at 97.5% accuracy. Upon further evaluation, the stability of LSTM Siamese models was observed to be consistent across diverse similarity functions, including cosine and Euclidean distances. Full article
(This article belongs to the Special Issue UAV-Assisted Mobile Wireless Networks and Applications)
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20 pages, 1412 KiB  
Article
Vibration Characteristic Research of 100 m New Polar Exploration Cruise Based on Finite Element Modeling
by Guohe Jiang, Yuhao Yuan, Hao Guo, Gang Wu and Zhenzhen Liu
J. Mar. Sci. Eng. 2024, 12(5), 779; https://doi.org/10.3390/jmse12050779 (registering DOI) - 07 May 2024
Abstract
Luxury cruise ships are high-end passenger ships with facilities on board for the leisure and entertainment of passengers, so the comfort of luxury cruise ships is a matter of great concern. In this paper, a finite element model of a new polar exploration [...] Read more.
Luxury cruise ships are high-end passenger ships with facilities on board for the leisure and entertainment of passengers, so the comfort of luxury cruise ships is a matter of great concern. In this paper, a finite element model of a new polar exploration cruise ship is established, and the wet modes of the whole ship are calculated using the virtual mass method and compared with the principal frequencies of the excitation forces to initially verify the rationality of the design of the structural vibration characteristics of the whole ship. The admittance matrix of the vibration velocity to excitation force was calculated by a frequency response analysis, and the vibration velocities at the stern plate and main engine foundations were tested during sailing. Then, the obtained propeller and main engine excitation forces were loaded into the finite element model; the vibration velocities of each compartment were calculated and compared with the compartment vibration velocity test values. The errors were within the engineering allowable range, verifying the accuracy of the excitation forces. The propeller and main engine excitation forces were loaded separately on the finite element model to calculate the vibration velocity of each cabin, and the contribution of the two excitation sources to the vibration velocity of each cabin was analyzed. It was found that the contribution of the excitation source to the cabin response was related to the relative position between the cabin and the excitation source. When the cabin was located in the cabin adjacent to or directly above a certain excitation source, the contribution of the excitation source to the cabin response was greater. When the cabin was farther away from both excitation sources, the contribution of the propeller excitation was greater. This provides a targeted reference for the preliminary vibration assessment and later vibration control of the new polar expedition cruise ship. Full article
(This article belongs to the Section Marine Hazards)
17 pages, 996 KiB  
Review
Genetic Variants in the ABCB1 and ABCG2 Gene Drug Transporters Involved in Gefitinib-Associated Adverse Reaction: A Systematic Review and Meta-Analysis
by Mariana Vieira Morau, Cecília Souto Seguin, Marília Berlofa Visacri, Eder de Carvalho Pincinato and Patricia Moriel
Genes 2024, 15(5), 591; https://doi.org/10.3390/genes15050591 (registering DOI) - 07 May 2024
Abstract
This systematic review and meta-analysis aimed to verify the association between the genetic variants of adenosine triphosphate (ATP)-binding cassette subfamily B member 1 (ABCB1) and ATP-binding cassette subfamily G member 2 (ABCG2) genes and the presence and severity of [...] Read more.
This systematic review and meta-analysis aimed to verify the association between the genetic variants of adenosine triphosphate (ATP)-binding cassette subfamily B member 1 (ABCB1) and ATP-binding cassette subfamily G member 2 (ABCG2) genes and the presence and severity of gefitinib-associated adverse reactions. We systematically searched PubMed, Virtual Health Library/Bireme, Scopus, Embase, and Web of Science databases for relevant studies published up to February 2024. In total, five studies were included in the review. Additionally, eight genetic variants related to ABCB1 (rs1045642, rs1128503, rs2032582, and rs1025836) and ABCG2 (rs2231142, rs2231137, rs2622604, and 15622C>T) genes were analyzed. Meta-analysis showed a significant association between the ABCB1 gene rs1045642 TT genotype and presence of diarrhea (OR = 5.41, 95% CI: 1.38–21.14, I2 = 0%), the ABCB1 gene rs1128503 TT genotype and CT + TT group and the presence of skin rash (OR = 4.37, 95% CI: 1.51–12.61, I2 = 0% and OR = 6.99, 95%CI: 1.61–30.30, I2= 0%, respectively), and the ABCG2 gene rs2231142 CC genotype and presence of diarrhea (OR = 3.87, 95% CI: 1.53–9.84, I2 = 39%). No ABCB1 or ABCG2 genes were positively associated with the severity of adverse reactions associated with gefitinib. In conclusion, this study showed that ABCB1 and ABCG2 variants are likely to exhibit clinical implications in predicting the presence of adverse reactions to gefitinib. Full article
(This article belongs to the Section Human Genomics and Genetic Diseases)
18 pages, 924 KiB  
Article
Modeling Yield of Irrigated and Rainfed Bean in Central and Southern Sinaloa State, Mexico, Based on Essential Climate Variables
by Omar Llanes Cárdenas, Rosa D. Estrella Gastélum, Román E. Parra Galaviz, Oscar G. Gutiérrez Ruacho, Jeován A. Ávila Díaz and Enrique Troyo Diéguez
Atmosphere 2024, 15(5), 573; https://doi.org/10.3390/atmos15050573 (registering DOI) - 07 May 2024
Abstract
The goal was to model irrigated (IBY) and rainfed (RBY) bean yields in central (Culiacán) and southern (Rosario) Sinaloa state as a function of the essential climate variables soil moisture, temperature, reference evapotranspiration, and precipitation. For Sinaloa, for the period 1982–2013 (October–March), the [...] Read more.
The goal was to model irrigated (IBY) and rainfed (RBY) bean yields in central (Culiacán) and southern (Rosario) Sinaloa state as a function of the essential climate variables soil moisture, temperature, reference evapotranspiration, and precipitation. For Sinaloa, for the period 1982–2013 (October–March), the following were calculated: (a) temperatures, (b) average degree days for the bean, (c) cumulative reference evapotranspiration, and (d) cumulative effective precipitation. For essential climate variables, (e) daily soil moisture obtained from the European Space Agency and (f) IBY and RBY from the Agrifood and Fisheries Information Service were used. Multiple linear regressions were significant for predicting IBY–RBY (dependent variables) as a function of essential climate variables (independent variables). The four models obtained were significantly predictive: IBY–Culiacán (Pearson correlation (PC) = 0.590 > Pearson critical correlation (CPC) = |0.349|), RBY–Culiacán (PC = 0.734 > CPC = |0.349|), IBY–Rosario (PC = 0.621 > CPC = |0.355|), and RBY–Rosario (PC = 0.532 > CPC = |0.349|). Due to the lack of irrigation depth data, many studies only focus on modeling RBY; this study is the first in Sinaloa to predict IBY and RBY based on essential climate variables, contributing to the production of sustainable food. Full article
(This article belongs to the Section Climatology)
14 pages, 674 KiB  
Article
Earliest Mule Remains from Early Bronze Age Central Anatolia
by Can Yümni Gündem
Animals 2024, 14(10), 1397; https://doi.org/10.3390/ani14101397 (registering DOI) - 07 May 2024
Abstract
This paper discusses the discoveries of early donkey and the earliest mule remains in Central Anatolia from the site Derekutuğun. This site represents the remains of a village dating back to the Early Bronze Age and Assyrian Trade Colonies period, associated with mining. [...] Read more.
This paper discusses the discoveries of early donkey and the earliest mule remains in Central Anatolia from the site Derekutuğun. This site represents the remains of a village dating back to the Early Bronze Age and Assyrian Trade Colonies period, associated with mining. The archaeofaunal assemblage was studied by the author and his team using classical archaeozoological methods. The dental remains of the Equidae found at Derekutuğun have been re-examined and are described in this article. The dental evidence indicates that donkeys, and possibly the earliest mules ever found in Central Anatolia, were kept at this site. Although the paper is based on the archaeozoological remains, written sources from the period also support the faunal identification. Derekutuğun was a small settlement that specialized in processing copper ore, and which was an important hub for a trade network because of its extensive mining and extraction operations. Full article
28 pages, 2589 KiB  
Review
AI-Driven Sensing Technology: Review
by Long Chen, Chenbin Xia, Zhehui Zhao, Haoran Fu and Yunmin Chen
Sensors 2024, 24(10), 2958; https://doi.org/10.3390/s24102958 (registering DOI) - 07 May 2024
Abstract
Machine learning and deep learning technologies are rapidly advancing the capabilities of sensing technologies, bringing about significant improvements in accuracy, sensitivity, and adaptability. These advancements are making a notable impact across a broad spectrum of fields, including industrial automation, robotics, biomedical engineering, and [...] Read more.
Machine learning and deep learning technologies are rapidly advancing the capabilities of sensing technologies, bringing about significant improvements in accuracy, sensitivity, and adaptability. These advancements are making a notable impact across a broad spectrum of fields, including industrial automation, robotics, biomedical engineering, and civil infrastructure monitoring. The core of this transformative shift lies in the integration of artificial intelligence (AI) with sensor technology, focusing on the development of efficient algorithms that drive both device performance enhancements and novel applications in various biomedical and engineering fields. This review delves into the fusion of ML/DL algorithms with sensor technologies, shedding light on their profound impact on sensor design, calibration and compensation, object recognition, and behavior prediction. Through a series of exemplary applications, the review showcases the potential of AI algorithms to significantly upgrade sensor functionalities and widen their application range. Moreover, it addresses the challenges encountered in exploiting these technologies for sensing applications and offers insights into future trends and potential advancements. Full article
(This article belongs to the Section State-of-the-Art Sensors Technologies)
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19 pages, 1580 KiB  
Article
Change in Dental Arch Parameters—Perimeter, Width and Length after Treatment with a Printed RME Appliance
by Vladimir Bogdanov, Greta Yordanova and Gergana Gurgurova
Appl. Sci. 2024, 14(10), 3959; https://doi.org/10.3390/app14103959 (registering DOI) - 07 May 2024
Abstract
One of the important parameters in orthodontics is the perimeter of the dental arch. Precise assessment is necessary in cases of maxillary constriction treated with a rapid maxillary expander (RME). The orthodontic software allows customization of the processes from diagnosis to manufacturing of [...] Read more.
One of the important parameters in orthodontics is the perimeter of the dental arch. Precise assessment is necessary in cases of maxillary constriction treated with a rapid maxillary expander (RME). The orthodontic software allows customization of the processes from diagnosis to manufacturing of the treatment device. The aim of the present study is to evaluate a relationship between the parameters of the dental arch—perimeter, width, and length—and to follow the changes during treatment. The study is based on the digital measurements of 3D models of 33 patients treated with a digitally planned and printed RME. In the results an increase of 3.99 mm in perimeter was achieved. The rest of the parameters were changed as follows: The width of the dental arch was increased in the premolar area by an average of 3.3 mm; in the area of the first molars, the increase was 4.41 mm; the length of the dental arch in the anterior segment was reduced by an average of 0.54 mm; and the whole length by 0.52 mm. Correlation between the studied variables was described by linear equations. In conclusion, rapid maxillary expansion is a reliable method for gaining predictable space in the dental arch. Full article
(This article belongs to the Special Issue Applications of Digital Dental Technology in Orthodontics)
20 pages, 1720 KiB  
Article
Integrating Cognitive Competency, Social Competency and Risk Propensity with the Theory of Planned Behaviour to Attain Sustainable-Development-Goal-8-Driven Sustainable Entrepreneurial Intentions
by Simpi Malhotra and Ravi Kiran
Sustainability 2024, 16(10), 3888; https://doi.org/10.3390/su16103888 (registering DOI) - 07 May 2024
Abstract
This paper empirically examines whether integrating entrepreneurial abilities with the theory of perceived behaviour positively influences Sustainable-Development-Goal-8-driven sustainable entrepreneurial intentions (SDG-8 SEIs). The data used in this study were gathered from 540 students from top-ranked Indian engineering colleges that offer entrepreneurship courses and [...] Read more.
This paper empirically examines whether integrating entrepreneurial abilities with the theory of perceived behaviour positively influences Sustainable-Development-Goal-8-driven sustainable entrepreneurial intentions (SDG-8 SEIs). The data used in this study were gathered from 540 students from top-ranked Indian engineering colleges that offer entrepreneurship courses and have access to company incubators. According to the theory of planned behaviour (TPB), perceived behavioural control, subjective norms, and entrepreneurial drive are the three elements of perceived entrepreneurial behaviour. The TPB’s dimensions in this study have entrepreneurial competencies as their antecedents. Cognitive competency, risk propensity, and social competency and resilience are antecedents of the TPB’s dimensions. One entrepreneurial viewpoint uses sustainable UNDP-SDG-8 as a metric for assessing intentions; its objectives are the promotion of inclusive and sustainable economic growth, full and productive employment, and decent work for all. This study used partial least squares structural equation modelling (PLS-SEM). According to the findings, engineering students in India are more likely to have entrepreneurial-focused intentions based on sustainability if they adhere to the TPB’s dimensions along with additional constructs. Using an expanded TPB model, we show that the TPB has learnable and stimulating antecedents, with these having a positive effect on SDG-8 SEIs, thus extending entrepreneurial activity in India. Policymakers, universities, and students will find these results very intriguing. The TPB’s dimensions and three additional dimensions are proposed as antecedents in a new conceptual model aimed at sustainable entrepreneurship in this study. Full article
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12 pages, 422 KiB  
Article
Superinfections of the Spine: A Single-Institution Experience
by Anthony K. Chiu, Bibhas Amatya, Idris Amin, Amit S. Ratanpal, Alexandra Baker Lutz, Brian M. Shear, Ivan B. Ye, Robin Fencel, Louis J. Bivona, Eugene Y. Koh, Julio J. Jauregui, Steven C. Ludwig and Daniel L. Cavanaugh
J. Clin. Med. 2024, 13(10), 2739; https://doi.org/10.3390/jcm13102739 (registering DOI) - 07 May 2024
Abstract
Background/Objectives: A superinfection occurs when a new, secondary organism colonizes an existing infection. Spine infections are associated with high patient morbidity and sometimes require multiple irrigations and debridements (I&Ds). When multiple I&Ds are required, the risk of complications increases. The purpose of this [...] Read more.
Background/Objectives: A superinfection occurs when a new, secondary organism colonizes an existing infection. Spine infections are associated with high patient morbidity and sometimes require multiple irrigations and debridements (I&Ds). When multiple I&Ds are required, the risk of complications increases. The purpose of this study was to report our experience with spine superinfections and determine which patients are typically affected. Methods: A retrospective case series of spine superinfections and a retrospective case–control analysis were conducted. Data were collected manually from electronic medical records. Spine I&Ds were identified. Groups were created for patients who had multiple I&Ds for (1) a recurrence of the same causative organism or (2) a superinfection with a novel organism. Preoperative demographic, clinical, and microbiologic data were compared between these two outcomes. A case series of superinfections with descriptive data was constructed. Lastly, two illustrative cases were provided in a narrative format. Results: A total of 92 patients were included in this analysis. Superinfections occurred after 6 out of the 92 (7%) initial I&Ds and were responsible for 6 out of the 24 (25%) repeat I&Ds. The preoperative erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) of the patients with a superinfection were significantly lower than those in the control group (p = 0.022 and p = 0.032). Otherwise, the observed differences in the preoperative variables were not statistically different. In the six cases of superinfection, the presence of high-risk comorbidities, a history of substance abuse, or a lack of social support were commonly observed. The superinfecting organisms included Candida, Pseudomonas, Serratia, Klebsiella, Enterobacter, and Staphylococcus species. Conclusions: Superinfections are a devastating complication requiring reoperation after initial spine I&D. Awareness of the possibility of superinfection and common patient archetypes can be helpful for clinicians and care teams. Future work is needed to examine how to identify, help predict, and prevent spine superinfections. Full article
(This article belongs to the Special Issue Neurosurgery and Spine Surgery: From Up-to-Date Practitioners)
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20 pages, 1737 KiB  
Article
CosUKG: A Representation Learning Framework for Uncertain Knowledge Graphs
by Qiuhui Shen and Aiyan Qu
Mathematics 2024, 12(10), 1419; https://doi.org/10.3390/math12101419 (registering DOI) - 07 May 2024
Abstract
Knowledge graphs have been extensively studied and applied, but most of these studies assume that the relationship facts in the knowledge graph are correct and deterministic. However, in the objective world, there inevitably exist uncertain relationship facts. The existing research lacks effective representation [...] Read more.
Knowledge graphs have been extensively studied and applied, but most of these studies assume that the relationship facts in the knowledge graph are correct and deterministic. However, in the objective world, there inevitably exist uncertain relationship facts. The existing research lacks effective representation of such uncertain information. In this regard, we propose a novel representation learning framework called CosUKG, which is specifically designed for uncertain knowledge graphs. This framework models uncertain information by measuring the cosine similarity between transformed vectors and actual target vectors, effectively integrating uncertainty into the embedding process of the knowledge graph while preserving its structural information. Through multiple experiments on three public datasets, the superiority of the CosUKG framework in representing uncertain knowledge graphs is demonstrated. It achieves improved representation accuracy of uncertain information without increasing model complexity or weakening structural information. Full article
(This article belongs to the Section Mathematics and Computer Science)
16 pages, 9570 KiB  
Review
Investigating the Balance between Structural Conservation and Functional Flexibility in Photosystem I
by Nathan Nelson
Int. J. Mol. Sci. 2024, 25(10), 5073; https://doi.org/10.3390/ijms25105073 (registering DOI) - 07 May 2024
Abstract
Photosynthesis, as the primary source of energy for all life forms, plays a crucial role in maintaining the global balance of energy, entropy, and enthalpy in living organisms. Among its various building blocks, photosystem I (PSI) is responsible for light-driven electron transfer, crucial [...] Read more.
Photosynthesis, as the primary source of energy for all life forms, plays a crucial role in maintaining the global balance of energy, entropy, and enthalpy in living organisms. Among its various building blocks, photosystem I (PSI) is responsible for light-driven electron transfer, crucial for generating cellular reducing power. PSI acts as a light-driven plastocyanin-ferredoxin oxidoreductase and is situated in the thylakoid membranes of cyanobacteria and the chloroplasts of eukaryotic photosynthetic organisms. Comprehending the structure and function of the photosynthetic machinery is essential for understanding its mode of action. New insights are offered into the structure and function of PSI and its associated light-harvesting proteins, with a specific focus on the remarkable structural conservation of the core complex and high plasticity of the peripheral light-harvesting complexes. Full article
(This article belongs to the Special Issue New Insights into Photosystem I)
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31 pages, 3425 KiB  
Article
Production and Optimisation of Fermented Pumpkin-Based Mature Coconut Water Kefir Beverage Using Response Surface Methodology
by Wee Yin Koh, Xiao Xian Lim, Ban Hock Khor, Babak Rasti, Thuan Chew Tan, Rovina Kobun and Utra Uthumporn
Beverages 2024, 10(2), 34; https://doi.org/10.3390/beverages10020034 (registering DOI) - 07 May 2024
Abstract
Fermentation of pumpkin puree and mature coconut water using water kefir grains is a potential method for producing a novel functional non-dairy-based probiotic drink. In the present study, response surface methodology based on Box–Behnken design (RSM-BBD) was used to optimise fermentation temperature and [...] Read more.
Fermentation of pumpkin puree and mature coconut water using water kefir grains is a potential method for producing a novel functional non-dairy-based probiotic drink. In the present study, response surface methodology based on Box–Behnken design (RSM-BBD) was used to optimise fermentation temperature and substrates’ concentrations. The optimised fermentation temperature, pumpkin puree, and brown sugar concentrations of pumpkin-based mature coconut water kefir beverage (PWKC) were 27 °C, 20%, and 10% w/v, respectively. The optimised PWKC (PWKCopt) obtained an overall acceptability (OA) score of 4.03, with a desirable Lactobacillus count (6.41 Log CFU/mL), 0.68% v/v lactic acid content, 31% of water kefir grains’ biomass growth rate, and fermentation time (to reach pH 4.5) of 4.5 h. The optimized beverage, PWKCopt, contained 3.26% proteins, 2.75% dietary fibre, 2186.33 mg/L of potassium, 180.67 mg/L phosphorus, and 137.33 mg/L calcium and had a total phenolic content of 89.93 mg GAE/100 mL, flavonoid content of 49.94 mg QE/100 mL, and carotenoid content of 33.24 mg/100 mL, with antioxidant activity (FRAP: 169.17 mM Fe(II)/100 mL, IC50 value of DPPH free radicals scavenging activity: 27.17 mg/mL). Water kefir microorganisms in PWKCopt remained stable for at least 56 days at 4 °C. Therefore, PWKCopt might potentially serve as a value-added product, offering a basis for sustainable development within both the coconut and pumpkin industries. Full article
(This article belongs to the Topic Advances in Analysis of Food and Beverages)
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21 pages, 944 KiB  
Review
A Review of Intelligent Airfoil Aerodynamic Optimization Methods Based on Data-Driven Advanced Models
by Liyue Wang, Haochen Zhang, Cong Wang, Jun Tao, Xinyue Lan, Gang Sun and Jinzhang Feng
Mathematics 2024, 12(10), 1417; https://doi.org/10.3390/math12101417 (registering DOI) - 07 May 2024
Abstract
With the rapid development of artificial intelligence technology, data-driven advanced models have provided new ideas and means for airfoil aerodynamic optimization. As the advanced models update and iterate, many useful explorations and attempts have been made by researchers on the integrated application of [...] Read more.
With the rapid development of artificial intelligence technology, data-driven advanced models have provided new ideas and means for airfoil aerodynamic optimization. As the advanced models update and iterate, many useful explorations and attempts have been made by researchers on the integrated application of artificial intelligence and airfoil aerodynamic optimization. In this paper, many critical aerodynamic optimization steps where data-driven advanced models are employed are reviewed. These steps include geometric parameterization, aerodynamic solving and performance evaluation, and model optimization. In this way, the improvements in the airfoil aerodynamic optimization area led by data-driven advanced models are introduced. These improvements involve more accurate global description of airfoil, faster prediction of aerodynamic performance, and more intelligent optimization modeling. Finally, the challenges and prospect of applying data-driven advanced models to aerodynamic optimization are discussed. Full article
(This article belongs to the Special Issue Advanced Model Optimization and Data Fusion Methods in Aircraft)
20 pages, 923 KiB  
Article
Assessing the Potential of Onboard LiDAR-Based Application to Detect the Quality of Tree Stems in Cut-to-Length (CTL) Harvesting Operations
by Anwar Sagar, Kalle Kärhä, Kalle Einola and Anssi Koivusalo
Forests 2024, 15(5), 818; https://doi.org/10.3390/f15050818 (registering DOI) - 07 May 2024
Abstract
This paper investigated the integration of LiDAR technology in cut-to-length (CTL) harvesting machines to enhance tree selection accuracy and efficiency. In the evolution of CTL forest machines towards improving operational efficiency and operator conditions, challenges persist in manual tree selection during thinning operations, [...] Read more.
This paper investigated the integration of LiDAR technology in cut-to-length (CTL) harvesting machines to enhance tree selection accuracy and efficiency. In the evolution of CTL forest machines towards improving operational efficiency and operator conditions, challenges persist in manual tree selection during thinning operations, especially under unmarked conditions and complex environments. These can be improved due to advances in technology. We studied the potential of LiDAR systems in assisting harvester operators, aiming to mitigate workload, reduce decision errors, and optimize the harvesting workflow. We used both synthetic and real-world 3D point cloud data sets for tree stem defect analysis. The former was crafted using a 3D modelling engine, while the latter originated from forest observations using 3D LiDAR on a CTL harvester. Both data sets contained instances of tree stem defects that should be detected. We demonstrated the potential of LiDAR technology: The analysis of synthetic data yielded a Root Mean Square Error (RMSE) of 0.00229 meters (m) and an RMSE percentage of 0.77%, demonstrating high detection accuracy. The real-world data also showed high accuracy, with an RMSE of 0.000767 m and an RMSE percentage of 1.39%. Given these results, we recommend using on-board LiDAR sensor technologies for collecting and analyzing data on tree/forest quality in real-time. This will help overcome existing barriers and drive forest operations toward enhanced efficiency and sustainability. Full article
(This article belongs to the Section Forest Operations and Engineering)

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