In recent years, Unmanned Aircraft System (UAS) usage in the medical sector as an alternative to traditional means of goods transport has grown significantly. Even though the reduced response time achieved with UASs can be lifesaving in critical situations, their usage must comply with technological constraints such as range, speed and capacity, while minimizing potential risks. In this paper, the feasibility of a drone operation dedicated to the transport of blood samples in an urban area is studied through a safety risk analysis. The assessment utilizes the Specific Operation Risk Assessment (SORA) framework, in line with current European regulations, and extends it to define flight trajectories with minimal risk. A case study in the Helsinki urban area is used as a reference, with an exemplary case of commercial drone transportation of blood samples between the Töölö and Malmi Hospitals. By leveraging the drone performance capabilities and minimizing the risk for people on the ground, this approach demonstrates that medical delivery using drones in densely populated urban environments remains challenging. Nonetheless, it argues that the proposed method can enhance risk awareness and support the planning of feasible operations. Full article

Digital transformation and “artificial intelligence (AI)”—which can more adequately be called “data-based systems (DS)”—comprise ethical opportunities and risks. Therefore, it is necessary to identify precisely ethical opportunities and risks in order to be able to benefit sustainably from the opportunities and to master the risks. The UN General Assembly has recently adopted a resolution aiming for ‘safe, secure and trustworthy artificial intelligence systems’. It is now urgent to implement and build on the UN General Assembly Resolution. Allowing humans and the planet to flourish sustainably in peace and guaranteeing globally that human dignity is respected not only offline but also online, in the digital sphere, and in the domain of DS, requires two policy measures: (1) human rights-based data-based systems (HRBDS): HRBDS means that human rights serve as the basis of digital transformation and DS. (2) International Data-Based Systems Agency (IDA): IDA should be established at the UN as a platform for cooperation in the field of digital transformation and DS, fostering human rights, security, and peaceful uses of DS, as well as a global supervisory institution and regulatory authority in digital transformation and DS. The establishment of IDA is realistic because humanity has already shown in its past that we are able to not always “blindly” pursue the technically possible but also to limit ourselves to what is technically feasible when humanity and the planet are at stake. For instance, humans researched the field of nuclear technology, developed the atomic bomb, and detonated it several times. Nonetheless, the same humans limited research and development in the field of nuclear technology to prevent even worse consequences by establishing the International Atomic Energy Agency (IAEA) at the UN. Full article

The Neoplatonic notion of “emanation” implies a required progression through hierarchical stages, originating from the highest principle (the One or God) and cascading down through a series of principles. While this process is deemed necessary, it is also inherently good, even “choiceworthy”, aligning with the identification of the first principle with the Good. Plotinus, a prominent Neoplatonist, emphasizes the beauty and goodness of the sensible world, governed by divine providence. This perspective, transmitted through Arabic adaptations of Plotinus, influences Islamic philosophers too. This paper delves into the thought of the Ismāʿīlī philosopher Abū Yaʿqūb al-Sijistānī (d. after. 349/971), exploring the interplay of necessity and goodness in his cosmology, with a focus on non-human animals. Sijistānī’s Persian Uncovering the Veiled provides a unique perspective on animals, presenting them as both necessary unfoldings of the universal intellect and inherently good beings with intrinsic value. The paper concludes with an appendix featuring an improved edition and English translation of relevant passages. Full article

This article explores the way a family fashioned a memorial to a son ‘taken by the war’. It focuses on the Robert’s collection in Melbourne, Australia’s largest bound collection of war time ephemera, and the making of what was called ‘Frank’s Memory Book’. It argues that families asserted ownership over their dead, crafting different modes of memorialization to authorized modes of remembrance, considers the way communities of mourners were brought together and highlights tensions between private loss and public memory. The making of ephemera is examined at length as is the part material culture plays in libraries and archives. Full article

This article explores findings from research into the impact of adoption throughout the life course of adults who were adopted in the era of secrecy, the 1940s–1970s. A narrative approach was used to explore their reflections, and semi-structured interviews were undertaken with 11 adults. The findings were then analysed through the lens of the Life Course Perspective. Previous studies on adoption have largely explored the outcomes of searching for birth family members, but few have focused on how adoptees went about this, the challenges they encountered, the decisions made and what happened as they began to dismantle layers of secrecy surrounding their adoption. For most of the participants, resources such as genealogical websites and particular guidance were not available at the time they were searching for birth information or attempting to make contact with birth families. Their accounts highlighted how social workers with potential birth information did not appear to be able to consider the broader emotional impact this might entail for adoptees. Initial meetings were described by some adoptees as hurdles to be overcome, and little birth information was given. Some continued to search for birth relatives without support, using random methods to gain contact. The ways in which adults went about their search sometimes appeared to suggest a lack of consideration or awareness on their part of the possible impact on others involved. In reality, they were faced with obstacles and barriers as they attempted to learn about their origins. Their stories provide a valuable insight into how adult adoptees sought to dismantle layers of secrecy, highlighting the complex, challenging and isolated situation they found themselves in as they searched for birth information and birth families, as well as the ethical challenges and dilemmas they had to negotiate in order to do so. Full article

Leaves are the predominant photosynthetic and edible organs in non-heading Chinese cabbage (Brassica campestris ssp. chinensis, NHCC), contributing significantly to yield, appearance, and desirability to consumers. However, the genetic basis of leaf shape and size in non-heading Chinese cabbage remains unclear. In this study, we developed a RIL population using ‘Maertou’, with slender leaves and narrow petioles, and ‘Suzhouqing’, with oval leaves and wide petioles, to construct a genetic linkage map and detect QTLs. To obtain stable and reliable QTLs, the 11 leaf-related traits, including the leaf length, leaf width, and fresh weight of the lamina and petiole and the thickness of petiole was observed on two locations—while the leaf shape, petiole shape, index of lamina/petiole length, and index of petiole fresh weight were calculated based on 7 leaf-related traits. QTL mapping illustrated that a total of 27 QTLs for leaf-related traits were preliminarily detected. The candidate genes were annotated and several genes involved in leaf development and leaf shape appeared in the overlapping regions of multiple loci, such as KRP2, GRF4, ARGOS, and SAUR9. This study lays the foundation for further exploration of the genetic mechanisms and development of effective molecular markers for leaf shape and size in NHCC. Full article

Understanding the origins and evolution of modern grapevine varieties in the Iberian Peninsula and western Europe necessitates an examination of the proportions of Vitis vinifera cultivars, their relationships with wild grapevine populations, and the utilization of seedless cultivars in al-Andalus. Employing morphometric studies, domestication indices, multivariate analysis, and Bayesian hypothesis testing, this study investigates several distinct seed types identified in materials from Roman and medieval deposits. These seeds exhibit a spectrum from highly domesticated to purely wild. Our findings reveal the predominance of Proles Occidentalis Negrul, and the presence of feral-like grapevines associated with Proles Euphratica. Additionally, we observe the continuous presence of wild grapevines related to Vitis sylvestris CC Gmelin throughout the studied period. Seeds exhibiting intermediate characteristics are documented, alongside the identification of “stenosperms”, suggesting anomalies in seed formation. Notably, the presence of Vitis vinifera raisins “stenospermocarpics” of the sultana type is suggested, potentially elucidating the absence of table grapes and raisins of the Proles Orientalis Negrul in the archaeological record, despite frequent mentions by medieval agronomy writers from al-Andalus. Full article

This study used Dutch potatoes at the end of dormancy as a material to explore the impact of menthol (0.2 and 0.5 g/kg based on potato mass) treatment on sprouting inhibition and potato quality. The findings revealed that a menthol concentration of 0.5 g/kg effectively inhibited potato tuber sprouting and significantly reduced glucoside alkaloid production. After a storage period of 15 days, the sprouting percentage and glucoside alkaloid content of potatoes treated with 0.5 g/kg menthol were observed to be significantly lower at 4.17% and 68.63 mg/kg, respectively, compared to the control group which exhibited values of 100% and 282.01 mg/kg, respectively (p < 0.05). Throughout the storage period, 0.5 g/kg of menthol promoted respiration, reduced malondialdehyde production in potatoes, inhibited polyphenol oxidase activity, and slowed down tissue browning. Additionally, it mitigated the decline in starch and soluble protein content, inhibiting the accumulation of reducing sugars. Full article

This study presents a novel approach to developing a probiotic butter spread product. We evaluated the prebiotic activity of soluble dietary fibers extracted from cranberry and sea buckthorn berry pomace with different probiotic strains (Limosilactobacillus reuteri, Lacticaseibacillus paracasei, and Lactiplantibacillus plantarum), uploaded selected compatible combination in the bigel matrix, and applied it in the probiotic butter spread formulation. Bigels and products were characterized by physical stability, rheological, textural properties, and viability of probiotics during storage at different conditions. The highest prebiotic activity score was observed in soluble cranberry (1.214 ± 0.029) and sea buckthorn (1.035 ± 0.009) fibers when cultivated with L. reuteri. The bigels loaded with probiotics and prebiotic fiber exhibited a significant increase in viscosity (higher consistency coefficient 40–45 Pa·sⁿ) and better probiotic viability (>6 log CFU/g) during long-term storage at +4 °C temperature, surpassing the bigels loaded with probiotics alone. Bigels stored at a lower temperature (−18 °C) maintained high bacterial viability (above 8.5 log CFU/g). The butter spread enriched with the bigel matrix was softer (7.6–14.2 N), indicating improved spreadability. The butter spread product consistently met the required 6 log CFU/g for a functional probiotic food product until 60 days of storage at +4 °C temperature. The butter stored at −18 °C remained probiotic throughout the entire storage period, confirming the protective effect of the bigel matrix. The study’s results showed the potential of the bigel to co-encapsulate, protect, and deliver probiotics during prolonged storage under different conditions. Full article

This work aims at understanding the level of financial literacy in Portugal, identifying the determinants of financial literacy in the Portuguese population, taking as an example certain sociodemographic factors such as gender and age. The aim is to understand whether there is a high level of adherence to financial literacy programs and initiatives, as well as the impact of financial knowledge variables on the financial literacy of the Portuguese population. The methodology used was quantitative and based on a questionnaire survey. The sample consisted of 600 individuals, all over 18 years old. It was concluded that individuals in the 26 to 35 age group had the best knowledge and that this sample showed better knowledge of interest rates compared to inflation and risk. The exploratory factor analysis shows five factors that determine the financial literacy of the Portuguese population and the way they manage their finances, which are (1) the perception of their current financial situation; (2) planning and controlling personal finances; (3) the perception of risky financial assets; (4) the perception of risk-free financial assets; and (5) savings. This research contributes to expanding scientific understanding in the field of financial literacy and offering support to the review of financial education policies by formulators, aiming to develop tools that help improve the financial behavior of the Portuguese population. Full article

Pain, particularly musculoskeletal (MSK) and multi-site pain, significantly impacts activities of daily living (ADL) in the elderly, leading to a decline in overall quality of life (QoL). This study, comprising 7490 participants, (mean age: 69 ± 10; females: 57%) from the sixth wave of the Korean Longitudinal Study of Aging (KLoSA), aimed to assess the association between self-reported pain and ADL impairment among the elderly population. Notably, 62% of participants reported experiencing pain, with back pain being the most prevalent (36%) and stomachache the least (0.39%). A majority (61%) of individuals reported MSK-related pain. Additionally, 20% reported pain at one site and 0.03% experienced pain at 12 sites. ADL impairment was observed in 376 (5.0%) participants. Compared to those without pain, participants reporting moderate and severe pain had higher odds of ADL impairment [2.31 (95% CI, 1.66–3.21) and 2.98 (95% CI, 1.95–4.53), respectively]. Pain experienced in the shoulder, arm, wrist, back, hip, leg, and ankle had a significant association with ADL impairment, with ORs ranging from 2.66 (95% CI, 1.80–3.93; hip pain) to 1.36 (95% CI 1.07–1.72; back pain). Furthermore, multi-site pain was associated with higher ADL impairment [1–6 sites: OR: 1.49 (95% CI, 1.11–2.01); 7–12 sites: OR: 7.16 (95% CI, 3.60–14.26)]. These findings underscore the importance of addressing MSK and multi-site pain through targeted interventions, potentially enhancing ADL and contributing to an improved QoL among the elderly population. Full article

This study examines the day-of-the-week effect on the returns of different classifications of South African REITs. Ordinary least squares regression (OLS), generalized autoregressive conditional heteroskedasticity (GARCH) (1,1) (2,1), and Kruskal–Wallis (KW) tests were performed on data obtained from the IRESS Expert database from 2013 to 2021. We found statistical differences in the day-of-the-week effects for SAREITs; the best day to invest in office REITs is Friday, for diversified REITs Thursday, and for industrial REITs Friday. Generally, Wednesday was found to be the least profitable day to invest in all REIT classifications because it had the least average daily return. Tuesdays were the most profitable days for all REIT classifications, with the highest average daily return. REITs traded the most on Fridays, while REITs traded the least on Mondays. Returns were the most volatile on Monday, while volume was the least volatile on Thursday. The KW test revealed a statistically significant difference between the median returns across days of the week. Based on the above, profitability is expressed on Tuesdays in South African REITs. By recognizing the day-of-the-week effect, investors can buy and sell South African REITs more effectively. This study, apart from being the first in the context of South African REITs, provides updated evidence of the contested calendar anomaly issues. Full article

The concept of sustainable water use serves as an indicator of environmental, economic, and social pressure on freshwater resources globally; however, the social element of sustainability is not well researched within water-consumption studies. The objective of this paper is to consider the current state of the literature on social sustainability indicators for water use in agriculture, as well as to describe the social (people) element of sustainability and establish water use as an element of society. By combining viewpoints, systematic literature reviews address research topics with a strength that no single work can have. From 314 papers published between 2013 and 2023, 42 papers were eligible for the review. This work employed a mixed-methods approach that included a systematic review following the (PRISMA) framework, scientific mapping through VOSviewer software (version 1.6.19), thematic reviews, and a review of the grey literature retrieved from artificial intelligence and deep learning technologies. The findings indicate that social sustainability indicators are based on environmental indicators. There are no set standards for what to consider as a social indicator of water use or for how these indictors can be measured. Life-cycle assessment and water-footprint assessment frameworks have shown progress with indicators that capture the social value of water such as productivity-reducing externalities, equity, and jobs per cubic metre of water. Full article

A novel H-shaped miniplate (HSM) was specifically designed for restorative laminoplasties to restore patients’ posterior elements after laminectomies. A validated finite element (FE) model of L2/4 was utilized to create a laminectomy model, as well as three restorative laminoplasty models based on the fixation of different miniplates after a laminectomy (the RL-HSM model, the RL-LSM model, and the RL-THM model). The biomechanical effects of motion and displacement on a laminectomy and restorative laminoplasty with three different shapes for the fixation of miniplates were compared under the same mechanical conditions. This study aimed to validate the biomechanical stability, efficacy, and feasibility of a restorative laminoplasty with the fixation of miniplates post laminectomy. The laminectomy model demonstrated the greatest increase in motion and displacement, especially in axial rotation, followed by extension, flexion, and lateral bending. The restorative laminoplasty was exceptional in preserving the motion and displacement of surgical segments when compared to the intact state. This preservation was particularly evident in lateral bending and flexion/extension, with a slight maintenance efficacy observed in axial rotation. Compared to the laminectomy model, the restorative laminoplasties with the investigated miniplates demonstrated a motion-limiting effect for all directions and resulted in excellent stability levels under axial rotation and flexion/extension. The greatest reduction in motion and displacement was observed in the RL-HSM model, followed by the RL-LSM model and then the RL-THM model. When comparing the fixation of different miniplates in restorative laminoplasties, the HSMs were found to be superior to the LSMs and THMs in maintaining postoperative stability, particularly in axial rotation. The evidence suggests that a restorative laminoplasty with the fixation of miniplates is more effective than a conventional laminectomy due to the biomechanical effects of restoring posterior elements, which helps patients regain motion and limit load displacement responses in the spine after surgery, especially in axial rotation and flexion/extension. Additionally, our evaluation in this research study could benefit from further research and provide a methodological and modeling basis for the design and optimization of restorative laminoplasties. Full article

The shelf life of whole wheat bread (WWB) significantly impacts its freshness and overall quality. This research investigated the impact of chitosan lactate (CL) on various characteristics influencing the shelf life of WWB, including its physical, chemical, textural, antimicrobial, and sensory attributes. These characteristics were evaluated by conducting various experiments such as physical inspection, moisture, impedance, swelling, color, texture, FTIR, microbiological, and sensory analysis. CL with different concentrations was incorporated into WWB formulations: P0.0 (0.0% w/w CL, control), P0.5 (0.5% w/w CL), P1.0 (1.0% w/w CL), P2.0 (2.0% w/w CL), and P3.0 (3.0% w/w CL). The inclusion of CL promoted the Maillard reaction (MR) compared to P0.0. The promotion of MR resulted in the formation of a shinier crust, which increased as the CL content was increased. P0.5 comprised large-sized pores and exhibited increased loaf height. CL-containing WWB formulations showed an increased moisture content and decreased impedance values compared to the control. FTIR analysis of P0.5 demonstrated the enhanced interaction and bonding of water molecules. P0.5 demonstrated optimal textural, colorimetric, and antimicrobial properties compared to other formulations. The sensory attributes of WWBs remain unchanged despite CL addition. In conclusion, P0.5 exhibited optimal characteristics associated with better quality and prolonged shelf life. Full article

The aim of this study was to evaluate the effect of extended maturation and temperature increase on the physico-chemical, biochemical, instrumental color and texture, sensory, and acceptability parameters of cured and boneless Iberian hams. Given the limited knowledge in this area, our objective was to develop a ham with enhanced proteolysis, potentially leading to increased bioactive peptide generation and superior sensory characteristics compared to salt-reduced counterparts. To achieve this, a batch of hams cured up to 38% loss at 30 °C and two batches cured up to 42% loss at 30 °C and 36 °C were evaluated. Results showed that the increase in processing time and temperature significantly enhanced (p < 0.05) ham proteolysis and amino acid content without adversely affecting its texture. No significant differences were observed in instrumental texture parameters or sensory attributes as evaluated by consumers. These processing conditions also increased the content of free amino acids, improving the product quality. Overall, these processing modifications resulted in hams with excellent sensory acceptability and enhanced bioactive potential despite the salt reduction. Full article

Smart cities like Neom require efficient and reliable transportation systems to support their vision of sustainable and interconnected urban environments. High-speed trains (HSTs) play a crucial role in connecting different areas of the city and facilitating seamless mobility. However, to ensure uninterrupted communication along the rail lines, advanced communication systems are essential to expand the coverage range of each base station (BS) while reducing the handover frequency. This paper presents the dual transceiver free space optical (FSO) communication system as a solution to achieve these objectives in the operational environment of HSTs in Neom city. Our channel model incorporates log-normal (LN) and gamma–gamma (GG) distributions to represent channel impairments and atmospheric turbulence in the city. Furthermore, we integrated the siding loop model, providing valuable insights into the system in real-world scenarios. To assess the system’s performance, we formulated the received signal-to-noise ratio (SNR) of the network under assumed fading conditions. Additionally, we analyzed the system’s bit error rate (BER) analytically and through Monte Carlo simulation. A comparative analysis with reconfigurable intelligent surfaces (RIS) and relay-assisted FSO communications shows the superior coverage area and efficiency of the dual transceiver model. A significant reduction of up to 76% and 99% in the number of required BSs compared to RIS and relay, respectively, is observed. This reduction leads to fewer handovers and lower capital expenditure (CAPEX) costs. Full article

During the hydraulic-fracturing process, stress interference occurs among multiple wells and fractures, potentially affecting the trajectory of hydraulic fracture propagation. Previous studies have largely overlooked the influence of proppant support stresses on the trajectories of fracture propagation. This paper establishes a mathematical model, grounded in the boundary element method, designed to compute the propagation of multiple fractures, considering both proppant support on the fracture surface and dynamic perturbations within the local stress field. The findings of this research reveal that the stress field induced by hydraulic fracturing exhibits dynamic evolution characteristics, necessitating a comprehensive study of the fracture initiation and extension across the entire fracturing time domain. The effect of the residual fracture width under proppant action on the in situ stress field cannot be ignored. During simultaneous fracturing, hydraulic fractures are inclined to propagate in the direction of the maximum horizontal principal stress, particularly as the in situ differential stress escalates. Staggered fracturing between wells has been proven to be more effective than head-to-head fracturing. Simply increasing the well spacing cannot solve the problem of inter-well fracture interference. In zipper fracturing, adjusting the fracturing sequence can inhibit the fracture intersections between wells, thereby controlling the trajectory of fracture propagation. The aforementioned research has considerable significance in guiding the control of fracture morphology during hydraulic-fracturing processes. Full article

Forest fires have emerged as a significant global concern, exacerbated by both global warming and the expanding human population. Several adverse outcomes can result from this, including climatic shifts and greenhouse effects. The ramifications of fire incidents extend widely, impacting human communities, financial resources, the natural environment, and global warming. Therefore, timely fire detection is essential for quick and effective response and not to endanger forest resources, animal life, and the human economy. This study introduces a forest fire detection approach utilizing transfer learning with the YOLOv8 (You Only Look Once version 8) pretraining model and the TranSDet model, which integrates an improved deep learning algorithm. Transfer Learning based on pre-trained YoloV8 enhances a fast and accurate object detection aggregate with the TranSDet structure to detect small fires. Furthermore, to train the model, we collected 5200 images and performed augmentation techniques for data, such as rotation, scaling, and changing due and saturation. Small fires can be detected from a distance by our suggested model both during the day and at night. Objects with similarities can lead to false predictions. However, the dataset augmentation technique reduces the feasibility. The experimental results prove that our proposed model can successfully achieve 98% accuracy to minimize catastrophic incidents. In recent years, the advancement of deep learning techniques has enhanced safety and secure environments. Lastly, we conducted a comparative analysis of our method’s performance based on widely used evaluation metrics to validate the achieved results. Full article

This study investigated how welding affects the thermal deformation of square cells produced for casks, which are dry storage containers for spent nuclear fuel. We aimed to minimize structural deformation by utilizing STS316L as the material for the square cells. We explored a method of subdividing the square cells and joining them through butt welding. Keeping the upper plate thickness constant, GTA butt welding was conducted while varying the column’s wall thickness, followed by measurement with a laser vision sensor. The heat conduction and thermal strain were then calculated using a finite element analysis (FEM). Both experimental and analytical results confirmed that there was significant thermal deformation in the cases of thick-walled columns due to variations in heat conduction distribution, with the resulting deformation patterns depending on thickness. Full article

In neonates with acute lung injury (ALI), targeting lower oxygenation saturations is suggested to limit oxygen toxicity while maintaining vital organ function. Although thresholds for cerebral autoregulation are studied for the management of premature infants, the impact of hypoxia on hemodynamics, tissue oxygen consumption and extraction is not well understood in term infants with ALI. We examined hemodynamics, cerebral autoregulation and fractional oxygen extraction, as measured by near-infrared spectroscopy (NIRS) and blood gases, in a neonatal porcine oleic acid injury model of moderate ALI. We hypothesized that in ALI animals, cerebral oxygen extraction would be increased to a greater degree than kidney or gut oxygen extraction as indicative of the brain’s adaptive efforts to increase cerebral oxygen extraction at the expense of splanchnic end organs. Fifteen anesthetized, ventilated 5-day-old neonatal piglets were divided into moderate lung injury by treatment with oleic acid or control (sham injection). The degree of lung injury was quantified at baseline and after establishment of ALI by blood gases, ventilation parameters and calculated oxygenation deficit, hemodynamic indices by echocardiography and lung injury score by ultrasound. PaCO₂ was maintained constant during ventilation. Cerebral, renal and gut oxygenation was determined by NIRS during stepwise decreases in inspired oxygen from 50% to 21%, correlated with PaO₂ and PvO₂; changes in fractional oxygen extraction (ΔFOE) were calculated from NIRS and from regional blood gas samples. The proportion of cerebral autoregulation impairment attributable to blood pressure, and to hypoxemia, was calculated from autoregulation nomograms. ALI manifested as hypoxemia with increasing intrapulmonary shunt fraction, decreased lung compliance and increased resistance, and marked increase in lung ultrasound score. Brain, gut and renal NIRS, obtained from probes placed over the anterior skull, central abdomen and flank, respectively, correlated with concurrent SVC (brain) or IVC (gut, renal) PvO₂ and SvO₂. Cerebral autoregulation was impaired after ALI as a function of blood pressure at all FiO₂ steps, but predominantly by hypoxemia at FiO₂ < 40%. Cerebral ΔFOE was higher in ALI animals at all FiO₂ steps. We conclude that in an animal model of neonatal ALI, cerebrovascular blood flow regulation is primarily dependent on oxygenation. There is not a defined oxygenation threshold below which cerebral autoregulation is impaired in ALI. Cerebral oxygen extraction is enhanced in ALI, reflecting compensation for exhausted cerebral autoregulation due to the degree of hypoxemia and/or hypotension, thereby protecting against tissue hypoxia. Full article