The 2023 MDPI Annual Report has
been released!
 
14 pages, 477 KiB  
Article
Growth, Hepatic Enzymatic Activity, and Quality of European Seabass Fed on Hermetia illucens and Poultry By-Product Meal in a Commercial Farm
by Lina Fernanda Pulido-Rodriguez, Leonardo Bruni, Giulia Secci, Sara Moutinho, Helena Peres, Tommaso Petochi, Giovanna Marino, Emilio Tibaldi and Giuliana Parisi
Animals 2024, 14(10), 1449; https://doi.org/10.3390/ani14101449 (registering DOI) - 13 May 2024
Abstract
Protein meals from insects in combination with poultry by-product meal appear to be promising ingredients for replacing conventional proteins in the diets of carnivorous fish. The present study explored the effects on growth performance, hepatic enzymatic activity, and fillet physical and nutritional characteristics [...] Read more.
Protein meals from insects in combination with poultry by-product meal appear to be promising ingredients for replacing conventional proteins in the diets of carnivorous fish. The present study explored the effects on growth performance, hepatic enzymatic activity, and fillet physical and nutritional characteristics during a 66-day feeding trial performed on European seabass. A total of 3000 fish were distributed into three tanks, where the control group was fed with a commercial diet (CG) and a second group was fed in duplicate with the experimental diet (SSH) containing 10% Hermetia illucens larva meal, 30% poultry by-product meal, and < 5.5 g/100 g of feed of marine origin proteins. All fish showed good growth performance. Glucose-6-phosphate dehydrogenase, aspartate aminotransferase, and 3-hydroxyacyl-CoA dehydrogenase activities were higher in the SSH group than in the CG group. The fillet fatty acid profile was largely unaffected by diet, except for a few fatty acids. Fish fed the SSH diet had a lower C22:1n-11 content than CG, thus suggesting an increased β-oxidation. The oxidative status of muscle lipids was not affected by the diet. In conclusion, the present study showed that European seabass can be successfully fed the SSH diet for two months in a commercial setting. Full article
33 pages, 1233 KiB  
Article
Insights into Simulated Smart Mobility on Roundabouts: Achievements, Lessons Learned, and Steps Ahead
by Maria Luisa Tumminello, Elżbieta Macioszek and Anna Granà
Sustainability 2024, 16(10), 4079; https://doi.org/10.3390/su16104079 (registering DOI) - 13 May 2024
Abstract
This paper explores the domain of intelligent transportation systems, specifically focusing on roundabouts as potential solutions in the context of smart mobility. Roundabouts offer a safer and more efficient driving environment compared to other intersections, thanks to their curvilinear trajectories promoting speed control [...] Read more.
This paper explores the domain of intelligent transportation systems, specifically focusing on roundabouts as potential solutions in the context of smart mobility. Roundabouts offer a safer and more efficient driving environment compared to other intersections, thanks to their curvilinear trajectories promoting speed control and lower vehicular speeds for traffic calming. The synthesis review supported the authors in presenting current knowledge and emerging needs in roundabout design and evaluation. A focused examination of the models and methods used to assess safety and operational performance of roundabout systems was necessary. This is particularly relevant in light of new challenges posed by the automotive market and the influence of vehicle-to-vehicle communication on the conceptualization and design of this road infrastructure. Two case studies of roundabouts were analyzed in Aimsun to simulate the increasing market penetration rates of connected and autonomous vehicles (CAVs) and their traffic impacts. Through microscopic traffic simulation, the research evaluated safety and performance efficiency advancements in roundabouts. The paper concludes by outlining areas for further research and evolving perspectives on the role of roundabouts in the transition toward connected and autonomous vehicles and infrastructures. Full article
(This article belongs to the Special Issue Sustainable Road Transport System Planning and Optimization)
25 pages, 2538 KiB  
Review
Related Work and Motivation for Electric Vehicle Solar/Wind Charging Stations: A Review
by Radwan A. Almasri, Talal Alharbi, M. S. Alshitawi, Omar Alrumayh and Salman Ajib
World Electr. Veh. J. 2024, 15(5), 215; https://doi.org/10.3390/wevj15050215 (registering DOI) - 13 May 2024
Abstract
The shift towards sustainable transportation is an urgent worldwide issue, leading to the investigation of creative methods to decrease the environmental effects of traditional vehicles. Electric vehicles (EVs) are a promising alternative, but the issue lies in establishing efficient and environmentally friendly charging [...] Read more.
The shift towards sustainable transportation is an urgent worldwide issue, leading to the investigation of creative methods to decrease the environmental effects of traditional vehicles. Electric vehicles (EVs) are a promising alternative, but the issue lies in establishing efficient and environmentally friendly charging infrastructure. This review explores the existing research on the subject of photovoltaic-powered electric vehicle charging stations (EVCSs). Our analysis highlights the potential for economic growth and the creation of robust and decentralized energy systems by increasing the number of EVCSs. This review summarizes the current knowledge in this field and highlights the key factors driving efforts to expand the use of PV-powered EVCSs. The findings indicate that MATLAB was predominantly used for theoretical studies, with projects focusing on shading parking lots. The energy usage varied from 0.139 to 0.295 kWh/km, while the cost of energy ranged from USD 0.0032 to 0.5645 per kWh for an on-grid system. The payback period (PBP) values are suitable for this application. The average PBP was demonstrated to range from 1 to 15 years. The findings from this assessment can guide policymakers, researchers, and industry stakeholders in shaping future advancements toward a cleaner and more sustainable transportation system. Full article
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11 pages, 4986 KiB  
Article
Gelatin-Coated TiO2/Pd Hybrid: A Potentially Useful Nanomaterial to Enhance Antibacterial and Anticancer Properties
by Periasamy Anbu, Muruganantham Rethinasabapathy, Anbazhagan Sathiyaseelan, Xin Zhang, Myeong-Hyeon Wang, Sekar Vijayakumar and Yun Suk Huh
Int. J. Mol. Sci. 2024, 25(10), 5308; https://doi.org/10.3390/ijms25105308 (registering DOI) - 13 May 2024
Abstract
Hybrid nanomaterials have attracted considerable interest in biomedicine because of their fascinating characteristics and wide range of applications in targeted drug delivery, antibacterial activity, and cancer treatment. This study developed a gelatin-coated Titanium oxide/palladium (TiO2/Pd) hybrid nanomaterial to enhance the antibacterial [...] Read more.
Hybrid nanomaterials have attracted considerable interest in biomedicine because of their fascinating characteristics and wide range of applications in targeted drug delivery, antibacterial activity, and cancer treatment. This study developed a gelatin-coated Titanium oxide/palladium (TiO2/Pd) hybrid nanomaterial to enhance the antibacterial and anticancer capabilities. Morphological and structural analyses were conducted to characterize the synthesized hybrid nanomaterial. The surface texture of the hybrid nanomaterials was examined by high-resolution transmission electron microscopy (HR-TEM) and field-emission scanning electron microscopy (FE-SEM). The FE-SEM image revealed the bulk of the spherically shaped particles and the aggregated tiny granules. Energy dispersive X-ray spectroscopy (EDS) revealed Ti, Pd, C, and O. X-ray diffraction (XRD) revealed the gelatin-coated TiO2/Pd to be in the anatase form. Fourier transform infrared spectroscopy examined the interactions among the gelatin-coated TiO2/Pd nanoparticles. The gelatin-coated TiO2/Pd nanomaterials exhibited high antibacterial activity against Escherichia coli (22 mm) and Bacillus subtilis (17 mm) compared to individual nanoparticles, confirming the synergistic effect. More importantly, the gelatin-coated TiO2/Pd hybrid nanomaterial exhibited remarkable cytotoxic effects on A549 lung cancer cells which shows a linear increase with the concentration of the nanomaterial. The hybrid nanomaterials displayed higher toxicity to cancer cells than the nanoparticles alone. Furthermore, the cytotoxic activity against human cancer cells was verified by the generation of reactive oxygen species and nuclear damage. Therefore, gelatin-coated TiO2/Pd nanomaterials have potential uses in treating cancer and bacterial infections. Full article
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11 pages, 255 KiB  
Article
Predictive Factors for Major Complications and Urological Cancer Diagnosis in Older Adults (≥80 Years) Admitted to the Emergency Department for Hematuria
by Mauro Ragonese, Daniele Fettucciari, Luigi Carbone, Filippo Gavi, Marco Montesi, Eros Scarciglia, Pierluigi Russo, Domenico Maria Sanesi, Filippo Marino, Nazario Foschi, Francesco Pinto, Francesco Franceschi, Marco Racioppi, Emilio Sacco and Marcello Covino
J. Clin. Med. 2024, 13(10), 2874; https://doi.org/10.3390/jcm13102874 (registering DOI) - 13 May 2024
Abstract
Background: Gross Hematuria is a relevant cause of admission to the emergency department in the general population and particularly in older adults (≥80 years). This specific urological symptom is often underestimated and usually associated with benign conditions such as urinary infections or [...] Read more.
Background: Gross Hematuria is a relevant cause of admission to the emergency department in the general population and particularly in older adults (≥80 years). This specific urological symptom is often underestimated and usually associated with benign conditions such as urinary infections or poor hydration. Nevertheless, hematuria could lead to severe acute complications or be the first symptom of urological cancers. Methods: We retrospectively analyzed clinical data from 1169 patients aged ≥80 years consecutively admitted to the emergency department for hematuria. The primary endpoint of the study was to identify risk factors for major complications, and the secondary endpoint was to analyze risk factors for urological cancer diagnosis. The median age was 85 years (IQR 82–88 years), and 908 (77%) were males. Among them, 449 (38.4%) had a past medical history of urological neoplasm (kidney, ureter, bladder, prostate, or urethral cancer). Results: Overall, 87 patients (7.4%) had major complications (patient death, septic shock, and admission to the intensive care unit). Worse vital signs at admission, fever, and confusion (p < 0.001, OR 18.0 IC 95% [5.5–58.7]; p = 0.015, OR 2.0 IC 95% [1.1–3.5]; p = <0.001, OR 4.2 IC 95% [1.9–3.5], respectively), as well as lower hemoglobin values and higher Charlson comorbidity index (p < 0.001, OR 0.8 IC 95% [0.7–0.9]), p = 0.002, OR = 1.2 [1.1–1.3]) were independent predictive factors for major complications. The multivariate analysis identified as risk factors for diagnosis of urological cancer older age, male sex and higher comorbidity (OR 1.05 IC95% [1–1.09]; OR 2.19 IC95% [1.42–3.39] and OR 1.11 IC95% [1.2–1.2], respectively); interestingly the presence of indwelling vesical catheter (IVC) (OR 0.44 IC95% [0.24–0.82]) resulted as an independent factor for absence of urological cancers. Conclusions: Hematuria is a frequent symptom in older adults admitted to the emergency department. While this is often associated with benign conditions, there are some risk factors for major complications and for urological cancer that must be taken into account to identify the patients who need further evaluation or prompt hospital admission. Full article
(This article belongs to the Special Issue Clinical Advances in Urologic Oncology)
30 pages, 3558 KiB  
Article
Multi-Strategy Improved Dung Beetle Optimization Algorithm and Its Applications
by Mingjun Ye , Heng Zhou, Haoyu Yang, Bin Hu and Xiong Wang
Biomimetics 2024, 9(5), 291; https://doi.org/10.3390/biomimetics9050291 (registering DOI) - 13 May 2024
Abstract
The dung beetle optimization (DBO) algorithm, a swarm intelligence-based metaheuristic, is renowned for its robust optimization capability and fast convergence speed. However, it also suffers from low population diversity, susceptibility to local optima solutions, and unsatisfactory convergence speed when facing complex optimization problems. [...] Read more.
The dung beetle optimization (DBO) algorithm, a swarm intelligence-based metaheuristic, is renowned for its robust optimization capability and fast convergence speed. However, it also suffers from low population diversity, susceptibility to local optima solutions, and unsatisfactory convergence speed when facing complex optimization problems. In response, this paper proposes the multi-strategy improved dung beetle optimization algorithm (MDBO). The core improvements include using Latin hypercube sampling for better population initialization and the introduction of a novel differential variation strategy, termed “Mean Differential Variation”, to enhance the algorithm’s ability to evade local optima. Moreover, a strategy combining lens imaging reverse learning and dimension-by-dimension optimization was proposed and applied to the current optimal solution. Through comprehensive performance testing on standard benchmark functions from CEC2017 and CEC2020, MDBO demonstrates superior performance in terms of optimization accuracy, stability, and convergence speed compared with other classical metaheuristic optimization algorithms. Additionally, the efficacy of MDBO in addressing complex real-world engineering problems is validated through three representative engineering application scenarios namely extension/compression spring design problems, reducer design problems, and welded beam design problems. Full article
(This article belongs to the Special Issue Nature-Inspired Metaheuristic Optimization Algorithms 2024)
15 pages, 655 KiB  
Article
Exploring Aggressive Behaviors in Greek Secondary Schools: Prevalence, Sociodemographic Factors, and Comparative Analysis with Elementary School Students
by Argyro Bourou, Petros Karkalousos, Anastasios G. Kriebardis and Effie Papageorgiou
Behav. Sci. 2024, 14(5), 405; https://doi.org/10.3390/bs14050405 (registering DOI) - 13 May 2024
Abstract
The main objectives of this study are to determine the prevalence of bullying in Greek secondary schools and detect the possible characteristics of bullies’ profiles in Greek school settings. A structured questionnaire was given to one hundred ninety-two (n= 192) educators at Greek [...] Read more.
The main objectives of this study are to determine the prevalence of bullying in Greek secondary schools and detect the possible characteristics of bullies’ profiles in Greek school settings. A structured questionnaire was given to one hundred ninety-two (n= 192) educators at Greek junior high schools in urban and rural areas. The educators were asked to report the frequencies and forms of aggressive behavior observed during the 2022–2023 school year, the bullies’ sociodemographic characteristics, and ways of dealing with bullying episodes. The data are presented, after conducting statistical analyses, in comparison with data for elementary school students. The results revealed that higher rates of bullying were reported compared with elementary school children. Moreover, according to teachers’ observations, aggressive behavior is independent of a pupil’s diagnosis, but specific types are correlated significantly with a pupil’s gender, nationality, low academic performance, and popularity. Factor analysis showed two main factors of aggression types, where common points and differences with elementary school students are mentioned. Implementations for the prevention of school bullying are discussed. Full article
13 pages, 2299 KiB  
Article
Effects of the Dual FAAH/MAGL Inhibitor AKU-005 on Trigeminal Hyperalgesia in Male Rats
by Rosaria Greco, Chiara Demartini, Miriam Francavilla, Anna Maria Zanaboni, Sara Facchetti, Michela Palmisani, Valentina Franco and Cristina Tassorelli
Cells 2024, 13(10), 830; https://doi.org/10.3390/cells13100830 (registering DOI) - 13 May 2024
Abstract
The inhibition of endocannabinoid hydrolysis by enzymatic inhibitors may interfere with mechanisms underlying migraine-related pain. The dual FAAH/MAGL inhibitor AKU-005 shows potent inhibitory activity in vitro. Here, we assessed the effect of AKU-005 in a migraine animal model based on nitroglycerin (NTG) administration. [...] Read more.
The inhibition of endocannabinoid hydrolysis by enzymatic inhibitors may interfere with mechanisms underlying migraine-related pain. The dual FAAH/MAGL inhibitor AKU-005 shows potent inhibitory activity in vitro. Here, we assessed the effect of AKU-005 in a migraine animal model based on nitroglycerin (NTG) administration. Male rats were treated with AKU-005 (0.5 mg/kg, i.p.) or vehicle 3 h after receiving NTG (10 mg/kg, i.p.) or NTG vehicle. One hour later, rats were subjected to the open field test followed by the orofacial formalin test. At the end of the test, we collected serum samples for assessing calcitonin gene-related peptide (CGRP) levels as well as meninges, trigeminal ganglia, and brain areas to assess mRNA levels of CGRP and pro-inflammatory cytokines, and endocannabinoid and related lipid levels. AKU-005 reduced NTG-induced hyperalgesia during the orofacial formalin test but did not influence NTG-induced changes in the open field test. It significantly reduced serum levels of CGRP, CGRP, and pro-inflammatory cytokine mRNA levels in the meninges, trigeminal ganglia, and central areas. Surprisingly, AKU-005 caused no change in endocannabinoids and related lipids in the regions evaluated. The present findings suggest that AKU-005 may have anti-migraine effects by reducing CGRP synthesis and release and the associated inflammatory events. This effect, however, does not seem mediated via an interference with the endocannabinoid pathway. Full article
(This article belongs to the Special Issue Migraine Neuroscience: From Experimental Models to Target Therapy)
12 pages, 321 KiB  
Article
Ecofeminism and the Cultural Affinity to Genocidal Capitalism: Theorising Necropolitical Femicide in Contemporary Greece
by Anastasia Christou
Soc. Sci. 2024, 13(5), 263; https://doi.org/10.3390/socsci13050263 (registering DOI) - 13 May 2024
Abstract
Resilient necrocapitalism and the zombie genre of representations of current dystopias are persistent in their political purpose in producing changes in the social order to benefit plutocracies around the world. It is through a thanatopolitical lens that we should view the successive losses [...] Read more.
Resilient necrocapitalism and the zombie genre of representations of current dystopias are persistent in their political purpose in producing changes in the social order to benefit plutocracies around the world. It is through a thanatopolitical lens that we should view the successive losses of life, and this zombie genre has come to represent a dystopia that, for political purposes, is intended to produce changes in societies which have tolerated the violent deaths of women. This article focuses on contemporary Greece and proposes a theoretical framework where femicide is understood as a social phenomenon that reflects a global gendered necropolitical logic which equals genocide. Such theoretical assemblages have to be situated within intersectional imperatives and tacitly as the result of the capitalist terror state performed in an expansive and direct immediate death, exacerbated by the lingering slow social death of the welfare state. The article contends that the scripted hetero-patriarchal social order of the necrocapitalist state poses a unique political threat to societies. With the silence of the complicity of the state, what is necessary is the creation and spread of new political knowledge and new social movements as resilient political tactics of resistance. This article foregrounds an ecofeminist perspective on these issues and considers ways through which new pedagogies of hope can counter the gendered necropolitics of contemporary capitalism in Greece. Full article
(This article belongs to the Special Issue Feminist Solidarity, Resistance, and Social Justice)
20 pages, 719 KiB  
Article
Application and Challenges of the Technology Acceptance Model in Elderly Healthcare: Insights from ChatGPT
by Sang Dol Kim
Technologies 2024, 12(5), 68; https://doi.org/10.3390/technologies12050068 (registering DOI) - 13 May 2024
Abstract
The Technology Acceptance Model (TAM) plays a pivotal role in elderly healthcare, serving as a theoretical framework. This study aimed to identify TAM’s core components, practical applications, challenges arising from its applications, and propose countermeasures in elderly healthcare. This descriptive study was conducted [...] Read more.
The Technology Acceptance Model (TAM) plays a pivotal role in elderly healthcare, serving as a theoretical framework. This study aimed to identify TAM’s core components, practical applications, challenges arising from its applications, and propose countermeasures in elderly healthcare. This descriptive study was conducted by utilizing OpenAI’s ChatGPT, with an access date of 10 January 2024. The three open-ended questions administered to ChatGPT and its responses were collected and qualitatively evaluated for reliability through previous studies. The core components of TAMs were identified as perceived usefulness, perceived ease of use, attitude toward use, behavioral intention to use, subjective norms, image, and facilitating conditions. TAM’s application areas span various technologies in elderly healthcare, such as telehealth, wearable devices, mobile health apps, and more. Challenges arising from TAM applications include technological literacy barriers, digital divide concerns, privacy and security apprehensions, resistance to change, limited awareness and information, health conditions and cognitive impairment, trust and reliability concerns, a lack of tailored interventions, overcoming age stereotypes, and integration with traditional healthcare. In conclusion, customized interventions are crucial for successful tech acceptance among the elderly population. The findings of this study are expected to enhance understanding of elderly healthcare and technology adoption, with insights gained through natural language processing models like ChatGPT anticipated to provide a fresh perspective. Full article
15 pages, 2170 KiB  
Article
Relative Expression of Genes Elicited by Clonostachys rosea in Pinus radiata Induces Systemic Resistance
by Priscila Moraga-Suazo, Regis Le-Feuvre, Dario Navarrete and Eugenio Sanfuentes
Forests 2024, 15(5), 854; https://doi.org/10.3390/f15050854 (registering DOI) - 13 May 2024
Abstract
Radiata pine is one of the most commonly planted tree species in Chile due to its fast growth and desirable wood and pulp properties. However, its productivity is hampered by several diseases. Pitch canker disease (PCC) caused by Fusarium circinatum, is considered [...] Read more.
Radiata pine is one of the most commonly planted tree species in Chile due to its fast growth and desirable wood and pulp properties. However, its productivity is hampered by several diseases. Pitch canker disease (PCC) caused by Fusarium circinatum, is considered the most damaging disease to the pine forest industry. Several control measures have been established, with biological control emerging as an environmentally friendly and effective way for F. circinatum control. Previous studies support the value of Clonostachys rosea in reducing PCC damage, with evidence suggesting a potential induced systemic resistance (ISR) triggered in radiata pines by this agent. Ten-month-old radiata pine plants were pre-treated with C. rosea on a substrate at 8 and 1 days before inoculation with F. circinatum on the stem tip, and expression levels were determined for DXS1, LOX, PAL, and PR3 genes 24 h later. Lesion length was 45% lower on plants pre-treated with C. rosea and infected with F. circinatum compared to non-pre-treated and infected plants. Additionally, LOX and PR3 were induced 23 and 62 times more, respectively, in comparison to untreated plants. Our results indicate that C. rosea causes an ISR response in pre-treated plants, significantly increasing the expression of resistance genes and reducing lesion length. Full article
(This article belongs to the Section Forest Health)
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21 pages, 8970 KiB  
Article
Lactobacillus delbrueckii subsp. bulgaricus Alleviates Acute Injury in Hypoxic Mice
by Ke Song, Hui Ling, Linlin Wang, Peijun Tian, Xing Jin, Jianxin Zhao, Wei Chen, Gang Wang and Yujing Bi
Nutrients 2024, 16(10), 1465; https://doi.org/10.3390/nu16101465 (registering DOI) - 13 May 2024
Abstract
Acute mountain sickness (AMS) is a common ailment in high-altitude areas caused by the body’s inadequate adaptation to low-pressure, low-oxygen environments, leading to organ edema, oxidative stress, and impaired intestinal barrier function. The gastrointestinal tract, being the first to be affected by ischemia [...] Read more.
Acute mountain sickness (AMS) is a common ailment in high-altitude areas caused by the body’s inadequate adaptation to low-pressure, low-oxygen environments, leading to organ edema, oxidative stress, and impaired intestinal barrier function. The gastrointestinal tract, being the first to be affected by ischemia and hypoxia, is highly susceptible to injury. This study investigates the role of Lactobacillus delbrueckii subsp. bulgaricus in alleviating acute hypoxic-induced intestinal and tissue damage from the perspective of daily consumed lactic acid bacteria. An acute hypoxia mouse model was established to evaluate tissue injury, oxidative stress, inflammatory responses, and intestinal barrier function in various groups of mice. The results indicate that strain 4L3 significantly mitigated brain and lung edema caused by hypoxia, improved colonic tissue damage, and effectively increased the content of tight junction proteins in the ileum, reducing ileal permeability and alleviating mechanical barrier damage in the intestines due to acute hypoxia. Additionally, 4L3 helped to rebalance the intestinal microbiota. In summary, this study found that Lactobacillus delbrueckii subsp. bulgaricus strain 4L3 could alleviate acute intestinal damage caused by hypoxia, thereby reducing hypoxic stress. This suggests that probiotic lactic acid bacteria that exert beneficial effects in the intestines may alleviate acute injury under hypoxic conditions in mice, offering new insights for the prevention and treatment of AMS. Full article
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20 pages, 4796 KiB  
Article
ABNet: An Aggregated Backbone Network Architecture for Fine Landcover Classification
by Bo Si, Zhennan Wang, Zhoulu Yu and Ke Wang
Remote Sens. 2024, 16(10), 1725; https://doi.org/10.3390/rs16101725 (registering DOI) - 13 May 2024
Abstract
High-precision landcover classification is a fundamental prerequisite for resource and environmental monitoring and land-use status surveys. Imbued with intricate spatial information and texture features, very high spatial resolution remote sensing images accentuate the divergence between features within the same category, thereby amplifying the [...] Read more.
High-precision landcover classification is a fundamental prerequisite for resource and environmental monitoring and land-use status surveys. Imbued with intricate spatial information and texture features, very high spatial resolution remote sensing images accentuate the divergence between features within the same category, thereby amplifying the complexity of landcover classification. Consequently, semantic segmentation models leveraging deep backbone networks have emerged as stalwarts in landcover classification tasks owing to their adeptness in feature representation. However, the classification efficacy of a solitary backbone network model fluctuates across diverse scenarios and datasets, posing a persistent challenge in the construction or selection of an appropriate backbone network for distinct classification tasks. To elevate the classification performance and bolster the generalization of semantic segmentation models, we propose a novel semantic segmentation network architecture, named the aggregated backbone network (ABNet), for the meticulous landcover classification. ABNet aggregates three prevailing backbone networks (ResNet, HRNet, and VoVNet), distinguished by significant structural disparities, using a same-stage fusion approach. Subsequently, it amalgamates these networks with the Deeplabv3+ head after integrating the convolutional block attention mechanism (CBAM). Notably, this amalgamation harmonizes distinct scale features extracted by the three backbone networks, thus enriching the model’s spatial contextual comprehension and expanding its receptive field, thereby facilitating more effective semantic feature extraction across different stages. The convolutional block attention mechanism primarily orchestrates channel adjustments and curtails redundant information within the aggregated feature layers. Ablation experiments demonstrate an enhancement of no less than 3% in the mean intersection over union (mIoU) of ABNet on both the LoveDA and GID15 datasets when compared with a single backbone network model. Furthermore, in contrast to seven classical or state-of-the-art models (UNet, FPN, PSPNet, DANet, CBNet, CCNet, and UPerNet), ABNet evinces excellent segmentation performance across the aforementioned datasets, underscoring the efficiency and robust generalization capabilities of the proposed approach. Full article
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21 pages, 4542 KiB  
Article
Experimental Study on the Clogging Performance of Waste Slag
by Shibo Li, Jinduo Chen, Jianquan Ma, Hao Li, Hao Guo, Yongqiang Qiu, Fuli Han and Yashu Ji
Water 2024, 16(10), 1390; https://doi.org/10.3390/w16101390 (registering DOI) - 13 May 2024
Abstract
The fine particles around a mining area are easy to transport under the climatic and hydrological actions such as rainfall, that causes the change in the permeability of accumulated slag and increases the hazard probability of slag debris flow. In this study, eight [...] Read more.
The fine particles around a mining area are easy to transport under the climatic and hydrological actions such as rainfall, that causes the change in the permeability of accumulated slag and increases the hazard probability of slag debris flow. In this study, eight experiments were designed to discuss the influence of fine particle migration on the permeability characteristics and clogging of slag accumulation in different graded particles and different dry densities. The results of experiments with coarse slags of five different particle sizes show that the ratio ranging from four to six in the coarse slag size and fine size caused a significant clogging phenomenon. It is confirmed that the shape of the particles is one of the factors affecting the clogging of coarse soil besides the coarse and fine particle size, and the clogging assessment criterion for slag and the corresponding clogging patterns based on the slag shape characteristics are given. And through three kinds of different dry density-graded slag, three clogging experiments were completed to verify the clogging standard and clogging particle size. The experimental results show that the clogging particle size obtained by the clogging criteria can effectively reduce the permeability of slag accumulation, and it is considered that the equivalent particle size and particle shape characteristics are the main factors affecting the clogging performance of accumulation, while the dry density of deposits has no significant influence on it. Full article
(This article belongs to the Topic Landslides and Natural Resources)
31 pages, 2572 KiB  
Article
Counter-Mapping in Geographic Education: A Novel Approach to Understanding Urban and Cultural Dynamics in Cities
by Seila Soler and Pablo Rosser
Heritage 2024, 7(5), 2507-2537; https://doi.org/10.3390/heritage7050120 (registering DOI) - 13 May 2024
Abstract
This study assessed the impact of counter-mapping on university students’ perception and knowledge of their cities, focusing on cultural diversity, urban dynamics, and social challenges. Using a quasi-experimental design with pretests and posttests in the province of Alicante, Spain, changes in the understanding [...] Read more.
This study assessed the impact of counter-mapping on university students’ perception and knowledge of their cities, focusing on cultural diversity, urban dynamics, and social challenges. Using a quasi-experimental design with pretests and posttests in the province of Alicante, Spain, changes in the understanding of urban geography, everyday life, and cultural diversity were analyzed among 54 Geography Didactics students. Likert scale surveys and open-ended questions were employed, complemented by statistical and qualitative analyses, to measure knowledge and perceptions before and after the counter-mapping project. The results indicate that although quantitative correlations did not show statistically significant significance, qualitative analysis revealed significant and profound learning. Participants uncovered the hidden layers of their urban environments and gained a better understanding of the complexities and challenges of their cities. The project promoted the development of critical skills such as analytical thinking, active research, and effective communication, proving to be a valuable pedagogical tool that surpasses the limitations of traditional teaching methods and encourages active and committed citizenship. This inclusive and multidimensional approach enriches the diversity of experiences and knowledge, significantly contributing to the teaching of urban subjects, community engagement, and social responsibility and laying the groundwork for the proper tourist, cultural, social, or urban planning of city spaces. Full article
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8 pages, 428 KiB  
Communication
Dental Abnormalities in Pediatric Patients Receiving Chemotherapy
by Tatsuya Akitomo, Masashi Ogawa, Ami Kaneki, Taku Nishimura, Momoko Usuda, Mariko Kametani, Satoru Kusaka, Yuria Asao, Yuko Iwamoto, Meiko Tachikake, Chieko Mitsuhata and Ryota Nomura
J. Clin. Med. 2024, 13(10), 2877; https://doi.org/10.3390/jcm13102877 (registering DOI) - 13 May 2024
Abstract
Background: Chemotherapy is a common treatment for pediatric cancer. Although life prognosis is improving because of advances in medical science, it is important to deal with late effects such as dental abnormalities. We investigated the association between dental abnormalities and chemotherapy by age [...] Read more.
Background: Chemotherapy is a common treatment for pediatric cancer. Although life prognosis is improving because of advances in medical science, it is important to deal with late effects such as dental abnormalities. We investigated the association between dental abnormalities and chemotherapy by age and tooth type. Methods: Among the 568 patients referred to the pediatric dentistry department of our hospital, we selected 32 patients (21 male and 11 female) who received chemotherapy between the ages of 0 and 6 and underwent panoramic examination after the age of 7. We recorded the age of chemotherapy commencement, diagnosis of systemic disease, and dental abnormalities such as congenital absence, microdonts, and short-rooted teeth. Results: Almost half of the patients had dental abnormalities such as congenital absence, microdonts, and short-rooted teeth, but there were no significant differences in the incidence of these abnormalities by age. When we analyzed the incidence of abnormal teeth by tooth type, the incidence of congenital absence was significantly higher in premolars (5.5%) and second molars (3.9%) than in incisor or canine or 1st molar (0.4%) (p < 0.01). The incidence of microdonts was significantly higher in premolars (3.9%) than in incisor or canine or 1st molar (0.2%) and second molars (0.0%) (p < 0.05). Conclusions: Patients who received chemotherapy had a high prevalence of dental abnormalities, and the incidence of abnormalities varied by tooth type. It is important to maintain long-term oral care for patients who have undergone chemotherapy even after the treatment is completed. Full article
(This article belongs to the Special Issue Pediatric Dentistry: Clinical Advances and Practice Updates)
16 pages, 717 KiB  
Article
A Study on Mineral Oil Hydrocarbons (MOH) Contamination in Pig Diets and Its Transfer to Back Fat and Loin Tissues
by Paula Albendea, Chiara Conchione, Luca Menegoz Ursol and Sabrina Moret
Animals 2024, 14(10), 1450; https://doi.org/10.3390/ani14101450 (registering DOI) - 13 May 2024
Abstract
This study assessed saturated mineral oil hydrocarbons (MOSH) and aromatic mineral oil hydrocarbons (MOAH) levels in grower–finisher feeds for pigs supplemented with 5% crude palm oil (CP), crude olive pomace oil (COP), olive pomace acid oil (OPA), or a blend of CP and [...] Read more.
This study assessed saturated mineral oil hydrocarbons (MOSH) and aromatic mineral oil hydrocarbons (MOAH) levels in grower–finisher feeds for pigs supplemented with 5% crude palm oil (CP), crude olive pomace oil (COP), olive pomace acid oil (OPA), or a blend of CP and OPA (50:50, w/w); the contribution of the lipid source to that contamination; and the ability of pigs to accumulate MOH in back fat and loin tissues after 60 days of trial. MOSH and MOAH were analyzed with liquid chromatography (LC)–gas chromatography (GC)–flame ionization detection (FID) after sample preparation. Among the lipid sources, CP had the lowest MOH levels, but CP feeds showed the highest contamination. This, along with the different MOSH profiles, indicated the presence of more significant contamination sources in the feeds than the lipid source. The higher MOH contamination in CP feeds was reflected in the highest MOSH levels in pig back fat, whereas MOAH were not detected in animal tissues. Also, MOSH bioaccumulation in pig tissues was influenced by the carbon chain length. In conclusion, feed manufacturing processes can determine the MOSH contamination present in animal adipose tissues that can be included in human diets. Full article
23 pages, 1095 KiB  
Article
Structural Shape Optimization Based on Multi-Patch Weakly Singular IGABEM and Particle Swarm Optimization Algorithm in Two-Dimensional Elastostatics
by Zhenyu Chen and Longtao Xie
Mathematics 2024, 12(10), 1518; https://doi.org/10.3390/math12101518 (registering DOI) - 13 May 2024
Abstract
In this paper, a multi-patch weakly singular isogeometric boundary element method (WSIGABEM) for two-dimensional elastostatics is proposed. Since the method is based on the weakly singular boundary integral equation, quadrature techniques, dedicated to the weakly singular and regular integrals, are applied in the [...] Read more.
In this paper, a multi-patch weakly singular isogeometric boundary element method (WSIGABEM) for two-dimensional elastostatics is proposed. Since the method is based on the weakly singular boundary integral equation, quadrature techniques, dedicated to the weakly singular and regular integrals, are applied in the method. A new formula for the generation of collocation points is suggested to take full advantage of the multi-patch technique. The generated collocation points are essentially inside the patches without any correction. If the boundary conditions are assumed to be continuous in every patch, no collocation point lies on the discontinuous boundaries, thus simplifying the implementation. The multi-patch WSIGABEM is verified by simple examples with analytical solutions. The features of the present multi-patch WSIGABEM are investigated by comparison with the traditional IGABEM. Furthermore, the combination of the present multi-patch WSIGABEM and the particle swarm optimization algorithm results in a shape optimization method in two-dimensional elastostatics. By changing some specific control points and their weights, the shape optimizations of the fillet corner, the spanner, and the arch bridge are verified to be effective. Full article
(This article belongs to the Special Issue Mathematical and Computational Methods for Mechanics and Engineering)
11 pages, 692 KiB  
Article
Economic Rationality in Decision-Making Regarding Newborn Screening: A Case Study in Quebec
by Van Hoa Ho, Yves Giguère and Daniel Reinharz
Int. J. Neonatal Screen. 2024, 10(2), 36; https://doi.org/10.3390/ijns10020036 (registering DOI) - 13 May 2024
Abstract
Health systems in high-resource countries recognize the importance of making decisions about the services offered to the population based on scientific evidence. Producing this evidence is especially challenging in areas such as newborn care where the frequency of conditions is rare. However, methodological [...] Read more.
Health systems in high-resource countries recognize the importance of making decisions about the services offered to the population based on scientific evidence. Producing this evidence is especially challenging in areas such as newborn care where the frequency of conditions is rare. However, methodological advances in the field of economic evaluation could change how this evidence is used in decision-making. This study aimed to investigate how decision-makers in the Canadian province of Quebec perceive the value of recent advances in economic evaluations for perinatal studies and how these advances might affect the offer of neonatal interventions in the public health care system. A qualitative study was conducted. A total of 10 policymakers were interviewed. A neo-institutional conceptual framework highlighting three dimensions, structure, power, and interpretive schemes, was used for data collection and analyses. Structural factors, interpretative schemes, and power management between the groups concerned concur to ensure that providing services to newborns is not hindered by the difficulty of producing evidence. They also ensure that the decisions regarding which disease to screen for take into consideration the specificity of neonatology, in particular, the social value given to children not captured by available evidence. Full article
21 pages, 5796 KiB  
Article
Estimation of Mechanical Properties of Aluminum Alloy Based on Indentation Curve and Projection Area of Contact Zone
by Yunfeng Bai and Chunguo Liu
Metals 2024, 14(5), 576; https://doi.org/10.3390/met14050576 (registering DOI) - 13 May 2024
Abstract
This study proposes a method for determining aluminum alloys’ yield stress and hardening index based on indentation experiments and finite element simulations. Firstly, the dimensionless analysis of indentation variables was performed on three different aluminum alloys using the same maximum indentation depth to [...] Read more.
This study proposes a method for determining aluminum alloys’ yield stress and hardening index based on indentation experiments and finite element simulations. Firstly, the dimensionless analysis of indentation variables was performed on three different aluminum alloys using the same maximum indentation depth to obtain load-displacement curves. Then, laser confocal microscopy was used to observe the residual indentation morphology. And four dimensionless parameters were derived from the load-displacement curves while another dimensionless parameter was obtained from the projection area of the contact zone. Subsequently, a genetic algorithm was employed to solve these five dimensionless parameters and estimate the yield stress and hardening index. Finally, the predicted results are compared with uniaxial tensile experiments and the results obtained are essentially the same. The yield stress and hardening index can be predicted using this method. And an example is used to verify that this method enables predictions for unidentified “mysterious material” and the expected results agree with the experiments. Full article
15 pages, 450 KiB  
Review
Contemporary Abdominal Wall Reconstruction: Emerging Techniques and Trends
by Kaylyn Pogson-Morowitz, Denisse Porras Fimbres, Brooke E. Barrow, Nicholas C. Oleck and Ash Patel
J. Clin. Med. 2024, 13(10), 2876; https://doi.org/10.3390/jcm13102876 (registering DOI) - 13 May 2024
Abstract
Abdominal wall reconstruction is a common and necessary surgery, two factors that drive innovation. This review article examines recent developments in ventral hernia repair including primary fascial closure, mesh selection between biologic, permanent synthetic, and biosynthetic meshes, component separation, and functional abdominal wall [...] Read more.
Abdominal wall reconstruction is a common and necessary surgery, two factors that drive innovation. This review article examines recent developments in ventral hernia repair including primary fascial closure, mesh selection between biologic, permanent synthetic, and biosynthetic meshes, component separation, and functional abdominal wall reconstruction from a plastic surgery perspective, exploring the full range of hernia repair’s own reconstructive ladder. New materials and techniques are examined to explore the ever-increasing options available to surgeons who work within the sphere of ventral hernia repair and provide updates for evolving trends in the field. Full article
(This article belongs to the Special Issue State-of-the-Art in Plastic Surgery)
23 pages, 1925 KiB  
Article
Farmland Rental Market, Outsourcing Services Market and Agricultural Green Productivity: Implications for Multiple Forms of Large-Scale Management
by Heng Zhang and Xiangyu Guo
Land 2024, 13(5), 676; https://doi.org/10.3390/land13050676 (registering DOI) - 13 May 2024
Abstract
Large-scale management is the key to realizing long-term agricultural growth in smallholder countries. Land-scale management and service-scale management are two forms of agricultural large-scale management. The former is committed to changing the small-scale management pattern, but the latter tends to maintain it. There [...] Read more.
Large-scale management is the key to realizing long-term agricultural growth in smallholder countries. Land-scale management and service-scale management are two forms of agricultural large-scale management. The former is committed to changing the small-scale management pattern, but the latter tends to maintain it. There has been a lack of discussion and controversy about the relationship between the two. From the perspective of market maturity, this paper explores whether the two are complementary or mutually exclusive and how their complementary or mutually exclusive relationship affects agricultural green productivity. The results show the following: Land-scale management and service-scale management are complementary, not superficially contradictory. The benign interaction between the two has a consistent improvement effect on green productivity in both the short and long term, which has spatial spillovers appearing in the long term. The reasons are as follows: The farmland rental market can reverse the inhibitory effect of the current low-maturity outsourcing services market on green productivity. The outsourcing services market can delay the arrival of the inflection point beyond which expansion of farmland rental transactions reduces green productivity, and amplify the positive effect of farmland rental on it. Although the degree of benign interaction between the two forms of large-scale management has gradually increased in recent years, it is still low overall. Agricultural large-scale management in China is still in the stage driven by land-scale management. Smallholder countries such as China need not worry prematurely about which large-scale management path to take, and they should treat both forms of large-scale management with an equal perspective to accelerate the high-level interaction between them. Full article
(This article belongs to the Special Issue Land Use Policy and Food Security)
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18 pages, 428 KiB  
Article
Movement Termination of Slow-Wave Sleep—A Potential Biomarker?
by Yvonne Höller, Stefanía Guðrún Eyjólfsdóttir, Matej Rusiňák, Lárus Steinþór Guðmundsson and Eugen Trinka
Brain Sci. 2024, 14(5), 493; https://doi.org/10.3390/brainsci14050493 (registering DOI) - 13 May 2024
Abstract
The duration of slow-wave sleep (SWS) is related to the reported sleep quality and to the important variables of mental and physical health. The internal cues to end an episode of SWS are poorly understood. One such internal cue is the initiation of [...] Read more.
The duration of slow-wave sleep (SWS) is related to the reported sleep quality and to the important variables of mental and physical health. The internal cues to end an episode of SWS are poorly understood. One such internal cue is the initiation of a body movement, which is detectable as electromyographic (EMG) activity in sleep-electroencephalography (EEG). In the present study, we characterized the termination of SWS episodes by movement to explore its potential as a biomarker. To this end, we characterized the relation between the occurrence of SWS termination by movement and individual characteristics (age, sex), SWS duration and spectral content, chronotype, depression, medication, overnight memory performance, and, as a potential neurological application, epilepsy. We analyzed 94 full-night EEG-EMG recordings (75/94 had confirmed epilepsy) in the video-EEG monitoring unit of the EpiCARE Centre Salzburg, Austria. Segments of SWS were counted and rated for their termination by movement or not through the visual inspection of continuous EEG and EMG recordings. Multiple linear regression was used to predict the number of SWS episodes that ended with movement by depression, chronotype, type of epilepsy (focal, generalized, no epilepsy, unclear), medication, gender, total duration of SWS, occurrence of seizures during the night, occurrence of tonic-clonic seizures during the night, and SWS frequency spectra. Furthermore, we assessed whether SWS movement termination was related to overnight memory retention. According to multiple linear regression, patients with overall longer SWS experienced more SWS episodes that ended with movement (t = 5.64; p = 0.001). No other variable was related to the proportion of SWS that ended with movement, including no epilepsy-related variable. A small sample (n = 4) of patients taking Sertraline experienced no SWS that ended with movement, which was significant compared to all other patients (t = 8.00; p < 0.001) and to n = 35 patients who did not take any medication (t = 4.22; p < 0.001). While this result was based on a small subsample and must be interpreted with caution, it warrants replication in a larger sample with and without seizures to further elucidate the role of the movement termination of SWS and its potential to serve as a biomarker for sleep continuity and for medication effects on sleep. Full article
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