An arbitrary Lagrangian-Eulerian lattice Boltzmann flux solver (ALE-LBFS) coupled with the mode superposition method is proposed in this work and applied to study two- and three-dimensional flutter phenomenon on dynamic unstructured meshes. The ALE-LBFS is applied to predict the flow field by using the vertex-centered finite volume method with an implicit dual time-stepping method. The convective fluxes are evaluated by using lattice Boltzmann solutions of the non-free D1Q4 lattice model and the viscous fluxes are obtained directly. Additional fluxes due to mesh motion are calculated directly by using local conservative variables and mesh velocity. The mode superposition method is used to solve for the dynamic response of solid structures. The exchange of aerodynamic forces and structural motions is achieved through interpolation with the radial basis function. The flow solver and the structural solver are tightly coupled so that the restriction on the physical time step can be removed. In addition, geometric conservation law (GCL) is also applied to guarantee conservation laws. The proposed method is tested through a series of simulations about moving boundaries and fluid–structure interaction problems in 2D and 3D. The present results show good consistency against the experiments and numerical simulations obtained from the literature. It is also shown that the proposed method not only can effectively predict the flutter boundaries in both 2D and 3D cases but can also accurately capture the transonic dip phenomenon. The tight coupling of the ALE-LBFS and the mode superposition method presents an effective and powerful tool for flutter prediction and can be applied to many essential aeronautical problems. Full article

A systematic review and meta-analysis was designed in order to ascertain the effectiveness of respiratory syncytial virus (RSV) vaccination in preventing lower respiratory tract diseases (LRTD) in older adults (age ≥ 60 years). Studies reporting on randomized controlled trials (RCTs) were searched for in three databases (PubMed, Embase, and Scopus) and the preprint repository medRxiv until 31 March 2024. A total of nine studies were eventually included, two of which were conference proceedings. Our analysis included five RCTs on five RSV vaccines (RSVpreF, RSVPreF3, Ad26.RSV.preF, MEDI7510, and mRNA-1345). The meta-analysis documented a pooled vaccine efficacy of 81.38% (95% confidence interval (95% CI) 70.94 to 88.06) for prevention of LRTD with three or more signs/symptoms during the first RSV season after the delivery of the vaccine. Follow-up data were available for RSVPreF3 (2 RSV seasons), RSVpreF (mid-term estimates of second RSV season), and mRNA-1345 (12 months after the delivery of the primer), with a pooled VE of 61.15% (95% CI 45.29 to 72.40). After the first season, the overall risk for developing RSV-related LRTD was therefore substantially increased (risk ratio (RR) 4.326, 95% CI 2.415; 7.748). However, all estimates were affected by substantial heterogeneity, as suggested by the 95% CI of I2 statistics, which could be explained by inconsistencies in the design of the parent studies, particularly when dealing with case definition. In conclusion, adult RSV vaccination was quite effective in preventing LRTD in older adults, but the overall efficacy rapidly decreased in the second season after the delivery of the vaccine. Because of the heterogenous design of the parent studies, further analyses are required before tailoring specific public health interventions. Full article

This online survey of unvaccinated people living in Japan aimed to identify the reasons for declining vaccination and to develop effective countermeasures. We conducted a hierarchical class analysis to classify participants, examine factors influencing their classification, and provide the information they needed about coronavirus disease 2019 (COVID-19) and trusted sources of COVID-19 information for each group. A total of 262 participants were classified into three groups: Group 1 with no specific reason (28 participants, 10.69%); Group 2 with clear concerns about trust in the vaccine (85 participants, 32.44%), and Group 3 with attitudinal barriers, such as distrust of the vaccine and complacency towards COVID-19, and structural barriers, such as vaccination appointments (149 participants, 56.87%). For each group, females tended to be classified in Group 2 more than Group 1 (Odds ratio (OR) [95% confidential intervals (95%CI)] = 1.64 (0.63 to 2.66), p = 0.001) and in Group 3 more than Group 1 (OR [95%CI] = 1.16 (0.19 to 2.12), p = 0.019). The information that the participants wanted to know about COVID-19 was different among each group (Safety: p < 0.001, Efficacy: p < 0.001, Genetic effects: p < 0.001). Those who did not receive the COVID-19 vaccine also had lower influenza vaccination coverage (8.02%). Additionally, 38 participants (14.50%) were subject to social disadvantages because they had not received the COVID-19 vaccine. Countermeasures should be carefully tailored according to the target population, reasons for hesitancy, and specific context. The findings of this study may help develop individualized countermeasures to address vaccine hesitancy. Full article

This cross-sectional study assessed the psychometric properties of the movement assessment battery for children second edition (M-ABC2) in Italian children with typical development, focusing on reliability and percentile rank establishment. The M-ABC2 is widely utilized but lacks validation in Italian populations. One hundred and eight children were recruited. Test-retest reliability was evaluated using intra-class correlation coefficients (ICCs), indicating good to excellent reliability across age groups, albeit with outliers requiring further scrutiny. Standard scores and percentile ranks were established, revealing age-related variations in motor performance. Noteworthy differences in completion times and error rates were observed among the age groups, highlighting the dynamic nature of motor development. While the findings provide valuable insights for clinicians and researchers, limitations such as sample size and geographic representation should be addressed in future studies. This study underscores the importance of employing reliable assessment tools for comprehensive understanding and effective intervention in pediatric motor development. Full article

Magnetic pulse welding (MPW) employs a strong pulsed magnetic field to accelerate parts against each other, thus forming an impact joint. Single-turn tool coils and field-shapers (FSs) used in MPW operate under the most demanding conditions, such as magnetic fields of 40–50 T with periods lasting tens of microseconds. With the use of conventional copper and bronze coils, intense thermo-mechanical stresses lead to the rapid degradation of the working bore. This work aimed to improve the efficiency of field-shapers and focused on the development of two- and four-slit FSs with a nanocomposite Cu 18Nb brazed wire acting as an inner current-carrying layer. The measured ratios of the magnetic field to the discharge current were 56.3 and 50.6 T/MA for the two- and four-slit FSs, respectively. FEM calculations of the magnetic field generated showed variations of 6–9% and 3% for the two- and four-slit FSs, respectively. The ovality percentages following copper tube compression were 27% and 7% for the two- and four-slit FSs, respectively. The measured deviations in the weld-joining length were 11% and 1.4% in the two- and four-slit FSs, respectively. Compared to the previous experiments on an entirely steel inductor, the novel FS showed significantly better results in terms of its efficiency and the homogeneity of its magnetic field. Full article

Burns are inevitable in modern warfare and have comprised between 5% and 20% of battlefield injuries. Involvement of the hands is the leading cause of postburn functional impairment. The purpose of this paper is to provide guidance on aspects of care necessary for the management of complex hand burns in a battlefield setting. Proper assessment and establishment of a comprehensive plan of care at the onset of injury help to ensure optimal functional outcomes in hand function. Basic treatment principles for the acutely burned hand include edema management; early wound coverage, including excision of the burn and skin grafting; early and aggressive hand therapy; and burn-scar contracture mitigation strategies. Full article

The early diagnosis and appropriate treatment of subclinical atherosclerosis before the onset of life-threatening cardiovascular (CV) diseases are major unmet medical needs in current clinical practice. Noninvasive arterial stiffness indices, the arterial velocity–pulse index (AVI) and the arterial pressure–volume index (API) have been associated with CV risks, conventional arterial stiffness indices, and the severity of coronary atherosclerosis. However, few studies have examined the relationship between these indices and the occurrence of CV events. We measured the AVI and API in 113 consecutive patients admitted to Yokohama City University Hospital for cardiac catheterization between June 2015 and March 2016. Patients were followed until September 2022, and the occurrence of CV events was assessed. The mean age was 71.2 ± 10.7 years, and 83 patients (73.5%) were male. In total, 80 patients (70.8%) had hypertension, 87 (77.0%) had dyslipidemia, and 91 (80.5%) had a history of ischemic heart disease (IHD). The mean follow-up duration was 1752 ± 819 days. Patients who received elective percutaneous coronary intervention (PCI) based on the results of coronary angiography (CAG) at the time of enrollment had significantly higher API than those who did not (38.5 ± 12.6, n = 17 vs. 31.3 ± 7.4, n = 96, p = 0.001). The API was independently associated with the risk of elective PCI in multiple logistic regression analysis. In conclusion, the API could be a useful indicator for estimating the need for coronary interventional treatment in patients with a high CV risk. Full article

A large core size and bending resistance are very important properties of mid-infrared energy transfer fibers, but large core sizes usually lead to the deterioration of bending properties. A negative-curvature nested node-free anti-resonant hollow-core fiber (AR-HCF) based on quartz is proposed. It was made by adding a nested layer to a previous AR-HCF design to provide an additional anti-resonance region while keeping the gap between adjacent tubes strictly correlated with the core diameter to produce a node-free structure. These features improve the fiber’s bending resistance while achieving a larger core diameter. The simulation results show that the radial air–glass anti-resonant layer is increased by the introduction of the nested anti-resonant tube, and the weak interference overlap between the fiber core and the cladding mode is reduced, so the fiber core’s limiting loss and sensitivity to bending are effectively reduced. When the capillary wall thickness t of the fiber is 0.71 μm, the core diameter D is 70 μm, the ratio of the inner diameter of the cladding capillary to the core diameter d/D is 0.62, the diameter of the nested tube is d₀ = 29 μm, the fiber has a lower limiting loss at the wavelength of 2.79 μm, and the limiting loss is 3.28 × 10⁻⁴ dB/m. At the same time, the optimized structure also has good bending resistance. When the bending radius is 30 mm, the bending loss is only 4.72 × 10⁻² dB/m. An anti-bending low-loss micro-structure hollow fiber with a bending radius of less than 30 mm was successfully achieved in the 2.79 μm band. An anti-bending low-loss anti-resonant hollow-core fiber with this structure constitutes a reliable choice for the light guiding system of a 2.79 μm band Er, Cr: YSGG laser therapy instrument. Full article

We present a comprehensive study of acral serpiginous hemangioma, a rare vascular pathology. This distinctive manifestation was examined for the first time using high-resolution video dermoscopy (HRVD), high-frequency ultrasound (HFUS), and line-field confocal optical coherence tomography (LC-OCT). The combined application of these techniques provides new and detailed morphological features able to determine the in vivo structure of lesional skin. This innovative non-invasive approach emphasizes the importance of incorporating advanced diagnostic tools able to provide a virtual histology in order to avoid unnecessary biopsies in benign lesions, often causing pain and functional/aesthetic discomfort. Full article

Controlling cell adhesion, viability, and proliferation on solid surfaces is critical for the successful implantation and proper functioning of temporary and permanent medical devices. While, with temporary or removable implants as well as surgical instruments, even slight cellular adhesion leads to an increased risk of secondary infections, bleeding and other complications, good cellular adhesion and viability are essential for the rapid healing and successful integration of permanent implants. This work was motivated by the growing interest in the construction of biocompatible and biodegradable coatings for the biofunctionalization of medical devices. Polysaccharide-based coatings are well known for their biocompatibility, but they are non-cell-adhesive, which hinders their application as implant coatings. In this study, we demonstrate that the incorporation of one or more graphene oxide layers in hyaluronic acid/chitosan multilayers is one avenue to regulate the degree of unspecific adhesion and growth of different cells (human umbilical vein endothelial cells, HUVEC, and mouse embryonic fibroblasts, 3T3). Furthermore, we demonstrate that this approach allows cell adhesion to be regulated across the entire range between completely prevented and highly promoted cell adhesion without introducing systemic cytotoxicity. These findings may contribute to the establishment of a new approach to adapt medical devices to cells and tissues. Full article

Parts of the Cantabrian Mountains (N Spain) have been colonized by woody species in the past six or seven decades as a result of a decline in livestock activity and changes in the fire regime. Various management strategies have been used to prevent the expansion of shrubs and recover grassland ecosystems for grazing activities. However, it is not clear how different vegetation treatments affect soils, which are crucial in supporting life and providing nutrients in these ecosystems. The aim of the present study was to compare the dynamics of the physicochemical and biological soil properties after two vegetation treatments: prescribed burning and shredding. Samples were obtained from plots representing alkaline and acidic soils dominated by gorse shrub (Genista hispanica subsp. occidentalis) and heath (Calluna vulgaris) plant communities, respectively. The soil samples were collected immediately before and after the treatments and one and two years later. The level of available P varied depending on the soil pH, and it only increased after the treatments in the acidic soils in the heathland community. The total N and available P concentrations were higher after the prescribed burning, and the enzymatic activity tended to be higher after the shredding treatment. Despite the significant effects on some soil variables, prescribed burning and shredding did not have important short- and medium-term effects on the chemical and soil enzymatic properties. These treatments can therefore be considered sustainable vegetation management tools, at least in the medium term. Full article

The long-term operation of motors induces substantial alterations in the surface conductivity and nonlinear coefficient of anti-corona paint, diminishing its efficacy and jeopardizing the longevity of large motors. Hence, the development of high-performance anti-corona paint holds paramount importance in ensuring motor safety. In this study, we integrate two nano-fillers, namely silicon carbide (SiC) and organic montmorillonite (O-MMT), into a composite matrix comprising micron silicon carbide and epoxy resin (SiC/EP). Subsequently, three distinct types of anti-corona paint are formulated: SiC/EP, Nano-SiC/EP, and O-MMT/SiC/EP. Remarkably, O-MMT/SiC/EP exhibits a glass transition temperature about 25 °C higher than that of SiC/EP, underscoring its superior thermal properties. Moreover, the introduction of nano-fillers markedly augments the surface conductivity of the anti-corona paint. Aging tests, conducted across varying temperatures, unveil a notable reduction in the fluctuation range of surface conductivity post-aging. Initially, the nonlinear coefficients exhibit a declining trend, succeeded by an ascending trajectory. The O-MMT/SiC/EP composite displays a maximum nonlinearity coefficient of 1.465 and a minimum of 1.382. Furthermore, the incorporation of nanofillers amplifies the dielectric thermal stability of epoxy resin composites, with O-MMT/SiC/EP showcasing the pinnacle of thermal endurance. Overall, our findings elucidate the efficacy of nano-fillers in enhancing the performance and longevity of anti-corona paint, particularly highlighting the exceptional attributes of the O-MMT/SiC/EP composite in bolstering motor safety through improved thermal stability and electrical properties. Full article

This paper examined a large sample of equity SMAs (separately managed accounts, hereafter) from 1999 to 2023. This paper found that separate accounts have much higher expenses than ETFs and may outperform or underperform ETFs in terms of gross return and net return depending on their investment styles. However, this paper found that separate accounts consistently outperform ETFs in terms of risk-adjusted gross and net return alphas across different investment styles using the Fama and French Three Factor Model. Additionally, this paper found no significant evidence that tax is proactively managed within separate accounts. Lastly, this paper found that on average SMAs’ risk-adjusted alphas do not persist over time. Full article

With the advancement of new food processing technology, triploid technology has emerged as a viable option to enhance plant yield and improve crop stress resistance. However, like many emerging technologies, food produced using triploid technology has sparked controversy regarding its safety since its inception. Particularly, consumers generally have a limited understanding of new technologies employed in food production, leading to concerns about potential risks and uncertainties associated with these technologies. Such concerns can significantly impact consumers’ acceptance and purchasing intentions toward foods modified using new technologies. This study collected 375 questionnaires from both online and offline sources and conducted a detailed analysis of consumers’ demographic variables, fear degree regarding triploid food, social trust, and concerns about food safety. SPSS and AMOS software were utilized for reliability and validity analysis, variance analysis, multiple comparisons, and confirmatory factor analysis. A structural equation model was developed to comprehensively examine consumers’ risk perception of triploid food and its influencing factors. The results indicate that consumers’ risk perception of triploid food is influenced by various factors. Notably, significant differences were found in consumers’ risk perception of triploid food based on age, educational background, residency, and employment status. Additionally, this study identified a negative correlation between consumers’ risk perception of triploid food and their levels of fear and social trust. Conversely, a positive correlation was observed between risk perception and the degree of attention given to food safety. Full article

Compared to regions with lighter pollution, the areas heavily affected by pollution in China face more severe environmental problems due to rapid economic growth, which creates a greater urgency for government and corporate environmental requirements. This study innovatively applies mediation and threshold models to explore the potential correlation between green technology innovation, types of environmental regulation, and provincial-level green total factor productivity (GTFP). Additionally, it examines inter-regional differences, determines threshold effects, and introduces regional heterogeneity and mediator variables. The research findings demonstrate that progress in green technology innovation significantly impacts the improvement of provincial-level GTFP. Further mechanism analysis reveals the crucial role of environmental regulation in facilitating sustained enhancement of GTFP through green technology innovation. The promotion of GTFP is more pronounced in eastern and central provinces compared to western regions, and the positive influence of green technology innovation varies significantly among provinces. By investigating the regional differences of polluted areas and introducing mediating variables, this paper explores the environmental regulation mechanism, which has important guiding significance for formulating more effective environmental regulation policies, promoting green technology innovation, and improving GTFP. Full article

Background: Awake craniotomy (AC) is recommended for the resection of tumors in eloquent areas. It is traditionally performed under monitored anesthesia care (MAC), which relies on hypnotics and opioids. Hypnosis-assisted AC (HAAC) is an emerging technique that aims to provide psychological support while reducing the need for pharmacological sedation and analgesia. We aimed to compare the characteristics and outcomes of patients who underwent AC under HAAC or MAC. Methods: We retrospectively analyzed the clinical, anesthetic, surgical, and neuropsychological data of patients who underwent awake surgical resection of eloquent brain tumors under HAAC or MAC. We used Mann–Whitney U tests, Wilcoxon signed-rank tests, and repeated-measures analyses of variance to identify statistically significant differences at the 0.05 level. Results: A total of 22 patients were analyzed, 14 in the HAAC group and 8 in the MAC group. Demographic, radiological, and surgical characteristics as well as postoperative outcomes were similar. Patients in the HAAC group received less remifentanil (p = 0.047) and propofol (p = 0.002), but more dexmedetomidine (p = 0.025). None of them received ketamine as a rescue analgesic. Although patients in the HAAC group experienced higher levels of perioperative pain (p < 0.05), they reported decreasing stress levels (p = 0.04) and greater levels of satisfaction (p = 0.02). Conclusion: HAAC is a safe alternative to MAC as it reduces perioperative stress and increases overall satisfaction. Further research is necessary to assess whether hypnosis is clinically beneficial. Full article

In modern warfare, frequency-hopping communication serves as the primary method for battlefield information transmission, with its significance continuously growing. Fighting for the control of electromagnetic power on the battlefield has become an important factor affecting the outcome of war. As communication electronic warfare evolves, jammers employing deep neural networks (DNNs) to decode frequency-hopping communication parameters for smart jamming pose a significant threat to communicators. This paper proposes a method to generate adversarial samples of frequency-hopping communication signals using adaptive whitening and feature gradient smoothing. This method targets the DNN cognitive link of the jammer, aiming to reduce modulation recognition accuracy and counteract smart interference. First, the frequency-hopping signal is adaptively whitened. Subsequently, rich spatiotemporal features are extracted from the hidden layer after inputting the signal into the deep neural network model for gradient calculation. The signal’s average feature gradient replaces the single-point gradient for iteration, enhancing anti-disturbance capabilities. Simulation results show that, compared with the existing gradient symbol attack algorithm, the attack success rate and migration rate of the adversarial samples generated by this method are greatly improved in both white box and black box scenarios. Full article

There is limited information on whether the COVID-19 pandemic was associated with decreased breast cancer screening uptake and if COVID-19 vaccination was associated with an increase in screening uptake. Our study explored the uptake of breast cancer screening in Japan after the COVID-19 pandemic and assessed its association with the COVID-19 vaccination. We analyzed data from the Japan COVID-19 and Society Internet Survey (JACSIS), a web-based prospective cohort survey, and we included 6100 women without cancer history who were aged 40 to 74 years that participated in the 2012 and 2022 surveys. We examined the regular breast cancer screening uptake before and after the pandemic and employed a multivariable Poisson regression model to seek any association between COVID-19 vaccination and screening uptake. Of 6110, 38.2% regularly participated in screening before the pandemic and 46.9% did so after the pandemic. Individuals unvaccinated due to health reasons (incidence rate ratio (IRR) = 0.47, 95% CI: 0.29–0.77, p = 0.003) and for other reasons (IRR = 0.73, 95% CI: 0.62–0.86, p < 0.001) were less likely to undergo screening compared to fully vaccinated individuals. There was no long-term decrease in breast cancer screening uptake after the pandemic in Japan. Vaccination was linked to increased uptake, but there was no dose relationship. Full article

Free-form surfaces in the automotive or aviation industry where the future shape of the product will contain complex surfaces raises the question of how to achieve the necessary shape of the required quality in the milling process. One of the methods of their production is the use of 5-axis milling, in which it is necessary to consider not only the input data of the process itself, but also the methodology for evaluating the desired results. Correctly answered questions can thus facilitate the choice of the inclination of the tool when machining parts of the surfaces defined in the experiment. The primary goal of the paper was to monitor the influence of tool inclination on the quality of the machined surface and effective cutting speed by evaluating surface roughness and surface topography. The experiment was designed to show the effect of different tool positions while the feed per tooth f_z for the finishing operation remained constant. The best result in terms of surface quality was achieved with a tool inclination of 15° in the cutting process. The most unfavorable result was obtained with a tool axis inclination of zero degrees due to unfavorable cutting conditions. Full article

The endophytic fungal biodiversity of unique plants like Peperomia argyreia (Miq.) É. Morren (Piperaceae) has antimicrobial properties and can be employed for infection treatment. Fungal isolates were obtained from appropriately treated plant tissues cultured in solid media, characterized by morphology, and identified by molecular biology using ITS and NL primers. The antimicrobial properties of fungal extracts were analyzed by combining microdilution and bioautographic assays complemented with metabolic profiling by automated thin-layer chromatography and ¹H NMR techniques. Thirty-one filamentous fungi were isolated and characterized by ITS and/or D1/D2 region amplification of rDNA, identified as Thermothielavioides, Trichoderma, Cyphellophora, Cladosporium, Arcopilus, Plectosphaerella; Chaetomium, Sporothrix, Alboefibula, and Penicillium. Thermothielavioides spp. inhibited Staphylococcus aureus ATCC 25923; moreover, Penicillium westlingii P4 showed inhibitory activity on Ascochyta rabiei AR2. The bioactivity-guided fractionation of the EtOAc extract (MIC = 62.5 μg/mL) of P. westlingii P4 allowed the purification of citrinin as the main inhibitory compound (MIC = 62.5 μg/mL). Peperomia argyreia harbors a rich and diverse endophytic community able to produce bioactive molecules. Citrinin, with a minor influence of volatile compounds biosynthesized by P. westlingii P4, was responsible for the inhibition of A. rabiei AR2. Full article

The cyclometalated terpyridine complexes [Ru(η²-OAc)(NC-tpy)(PP)] (PP = dppb 1, (R,R)-Skewphos 4, (S,S)-Skewphos 5) are easily obtained from the acetate derivatives [Ru(η²-OAc)₂(PP)] (PP = dppb, (R,R)-Skewphos 2, (S,S)-Skewphos 3) and tpy in methanol by elimination of AcOH. The precursors 2, 3 are prepared from [Ru(η²-OAc)₂(PPh₃)₂] and Skewphos in cyclohexane. Conversely, the NNN complexes [Ru(η¹-OAc)(NNN-tpy)(PP)]OAc (PP = (R,R)-Skewphos 6, (S,S)-Skewphos 7) are synthesized in a one pot reaction from [Ru(η²-OAc)₂(PPh₃)₂], PP and tpy in methanol. The neutral NC-tpy 1, 4, 5 and cationic NNN-tpy 6, 7 complexes catalyze the transfer hydrogenation of acetophenone (S/C = 1000) in 2-propanol with NaOiPr under light irradiation at 30 °C. Formation of (S)-1-phenylethanol has been observed with 4, 6 in a MeOH/iPrOH mixture, whereas the R-enantiomer is obtained with 5, 7 (50–52% ee). The tpy complexes show cytotoxic activity against the anaplastic thyroid cancer 8505C and SW1736 cell lines (ED₅₀ = 0.31–8.53 µM), with the cationic 7 displaying an ED₅₀ of 0.31 µM, four times lower compared to the enantiomer 6. Full article

With the unexpected onset of COVID-19, governments across the world responded with a range of preventive measures, including the imposition of lockdowns. To mitigate the adverse effects of lockdowns arising from supply chain shocks and employment loss, governments worldwide chose to implement policies to stimulate their economies and keep them working. This study assesses the impact and effectiveness of four of these packages in Bangladesh, employing a mixed-method approach. These packages include “salary support for workers in export-oriented RMG industries”, “working capital loans for affected industries and service sectors”, “working capital loans for cottage, micro, small, and medium enterprises”, and initiatives for “revitalizing the rural economy and job creation”. Each package was examined individually because of their differences in beneficiary groups, implementation methods, and individual objectives. Quantitative analysis involved propensity score matching (PSM), the difference in difference model (DID), and structural equation modelling (SEM). Stakeholders, including policy implementers, Bangladesh Bank officials, policy analysts, academics, workers, and beneficiaries, contributed to the qualitative analysis through extensive key-informant interviews, providing a comprehensive assessment of intervention outcomes. Ultimately, the results show that the packages achieved their socio-economic relief objectives for beneficiaries. The research examined both positive impacts and challenges in their implementation. It suggests that all four packages successfully achieved their goals, such as providing social and economic support, sustaining livelihoods, addressing marginalized groups’ needs, ensuring survival for large industries and small businesses, and promoting employment. In order to better address future shocks, establishing a beneficiary database integrated with the national system is recommended for smoother policy rollout. Despite acknowledged limitations, including challenges in beneficiary identification, data availability, and time constraints, the study’s unbiased estimations provide valuable insights to guide future policy directions in similar situations. Full article