(1) Background: This study aimed to determine whether standard-dose vitamin D supplementation could provide adequate levels in exclusively breastfed infants born with different cord 25(OH)D levels and to evaluate related neonatal morbidities. (2) Methods: A prospective cross-sectional study was designed in term infants. Three groups were formed based on cord 25(OH)D levels; Group1 Deficiency:25(OH)D < 12 ng/mL, Group2 Insufficiency:25(OH)D = 12–19 ng/mL, and Group3 Optimum:25(OH)D = 20–100 ng/mL. Cord and 1st month 25(OH)D levels, after receiving standard-dose vitamin D prophylaxis, neonatal outcomes and anthropometric measurements were compared. (3) Results: The study involved 86 infants. Group1 Deficiency had also significantly lower 25(OH)D levels at 1st month compared to the others (p < 0.001). There was a significant positive correlation between cord and 1st month 25(OH)D levels (r = 0.78, p < 0.001). Despite the fact that the mother’s age and clothing style were similar, Group1 Deficiency mothers had higher parity numbers and used less vitamin D during pregnancy (p = 0.03, p = 0.04). Neonatal outcomes analysis revealed that newborns in Group1 Deficiency experienced more respiratory distress, transient tachypnea, and early-onset sepsis, as well as more and longer hospital stays in the first-month of life (p < 0.05). (4) Conclusions: Infants with low cord 25(OH)D levels had also lower 25(OH)D values in the 1st month of life and experienced higher rates of neonatal morbidities. Given its numerous biological activities and impact on neonatal morbidities, determining an individualized dose of vitamin D supplementation may be more accurate than using the standard approach. Full article

Infants born prematurely are considered at risk for language development delay and impairments. Using online parental reports, the present study investigated the influence of early musical experience in the home environment (Music@Home Infant Questionnaire) on language development (MacArthur–Bates Communicative Development Inventory) while controlling for general enrichment at home (Stim-Q Cognitive Home Environment Questionnaire) and perinatal post-traumatic stress disorder (Perinatal PTSD Questionnaire). Caregivers of 117 infants between 8 and 18 months of age (corrected age) without reported developmental difficulties completed an online survey. Results revealed that the musical home environment significantly predicted outcomes in reported infants’ receptive vocabulary and gestural communication, independently from infants’ corrected age and general enrichment of home activities. These findings constitute the first evidence that an enriched musical experience can enhance the development of early communication skills in a population at risk for language delays, namely infants born prematurely, opening the path for future intervention research in home and/or early childcare settings. Given that the majority of participants in this study were highly educated and from socioeconomically stable backgrounds, considerations regarding the generalizability of these results are discussed. Full article

Efficiency in stock markets is essential for economic stability and growth. This study investigates the efficiency and herding behavior of the stock markets from the top economies of the world (known as G20 countries). We classify stock market indices using MSCI classification for the developed and emerging markets to provide a comparative examination using the latest data and by employing the robust multifractal detrended fluctuation (MFDFA) method. In addition to the full sample, the analysis uses sub-sample periods to reveal the hidden features and efficiencies of the G20 markets during the Russia–Ukraine War and COVID-19 for the first time. The findings show the availability of varied multifractality among all G20 stock markets during the overall and crisis periods, exhibit long-range correlations, and may support the fractal market hypothesis. In addition, Italy remains the least efficient, while Germany remains the most efficient stock market. The sub-sample results further reveal unevenness in the local fluctuations and resultant higher inefficiency considering the sheer magnitude and impact of crises on the G20 stock markets. However, the efficiency of developed stock markets performed better as compared to emerging markets. The study of G20 stock markets is useful and provides several implications for a wider audience. Full article

Institutional, policy, and management scholars and practitioners are increasingly interested in leveraging network perspectives, methods, and data to understand complex social phenomena, including the various stages of the policy process, community mobilization, and coupled natural and human systems. Viewing these phenomena through the lens of system-oriented networks can be valuable for understanding and intervening within complex policy arenas. However, currently, there is no clear consensus on who and what constitutes a relevant actor in a system-oriented network. Furthermore, numerous conceptual and methodological traditions for conceptualizing, measuring, and analyzing system-oriented networks have arisen, and each is linked to different disciplinary traditions. In this paper, we showcase six approaches from the public policy and public management literature for conceptualizing and analyzing system-oriented networks. We offer a conceptual framework for characterizing different approaches which considers differences in their focal system of interest, analytical focus, theoretical orientation, and approach for determining network boundaries. We review these elements with an eye toward helping scholars and practitioners interested in system-oriented networks to make informed decisions about the array of available approaches. Full article

This paper investigates the durability of geopolymers and geopolymeric mortars made with metakaolin and alkaline activators, with and without a coconut fiber addition, after immersion for seven days into solutions of citric acid (1%, 2.5%, 5%, and 10%); hydrochloric acid (1%, 2.5%, 5%, and 10%); and sulfuric acid (1%, 2.5%, 5%, and 10%). The study focuses on mass changes, uniaxial compressive strength, flexural strength, and ultrasound pulse velocity measurements. X-ray diffraction and scanning electron microscopy are used to analyze the degradation products and microstructural changes. The aim is to assess the effect of acid exposure on the strength and stability of geopolymer materials and identify any protective effects of coconut fiber reinforcement. The samples are immersed in acid solutions of varying concentrations, and their mechanical properties are measured. The presence of coconut fibers slightly modifies the physical properties and the compressive strength, improving the mechanical flexural strength. Geopolymer and geopolymeric mortar materials experienced a weak decrease in strength when exposed to solutions of citric acid and a significant one when exposed to solutions of hydrochloric and sulfuric acids, attributed to depolymerization of the aluminosilicate binders. Brick waste geopolymeric mortars reinforced with coconut fibers showed the best performance in acid solutions with respect to geopolymers and quartz-rich sand geopolymeric mortars, suggesting a more stable cross-linked aluminosilicate geopolymer structure in this material. Full article

In the context of increasing reliance on mobile devices, robust personal security solutions are critical. This paper presents Zero-FVeinNet, an innovative, lightweight convolutional neural network (CNN) tailored for finger vein recognition on mobile and embedded devices, which are typically resource-constrained. The model integrates cutting-edge features such as Zero-Shuffle Coordinate Attention and a blur pool layer, enhancing architectural efficiency and recognition accuracy under various imaging conditions. A notable reduction in computational demands is achieved through an optimized design involving only 0.3 M parameters, thereby enabling faster processing and reduced energy consumption, which is essential for mobile applications. An empirical evaluation on several leading public finger vein datasets demonstrates that Zero-FVeinNet not only outperforms traditional biometric systems in speed and efficiency but also establishes new standards in biometric identity verification. The Zero-FVeinNet achieves a Correct Identification Rate (CIR) of 99.9% on the FV-USM dataset, with a similarly high accuracy on other datasets. This paper underscores the potential of Zero-FVeinNet to significantly enhance security features on mobile devices by merging high accuracy with operational efficiency, paving the way for advanced biometric verification technologies. Full article

Enterovirus 71 (EV71), a typical representative of unenveloped RNA viruses, is the main pathogenic factor responsible for hand, foot, and mouth disease (HFMD) in infants. This disease seriously threatens the health and lives of humans worldwide, especially in the Asia–Pacific region. Numerous animal antimicrobial peptides have been found with protective functions against viruses, bacteria, fungi, parasites, and other pathogens, but there are few studies on the use of scorpion-derived antimicrobial peptides against unenveloped viruses. Here, we investigated the antiviral activities of scorpion venom antimicrobial peptide BmKn2 and five derivatives, finding that BmKn2 and its derivative BmKn2-T5 exhibit a significant inhibitory effect on EV71. Although both peptides exhibit characteristics typical of amphiphilic α-helices in terms of their secondary structure, BmKn2-T5 displayed lower cellular cytotoxicity than BmKn2. BmKn2-T5 was further found to inhibit EV71 in a dose-dependent manner in vitro. Moreover, time-of-drug-addition experiments showed that BmKn2-T5 mainly restricts EV71, but not its virion or replication, at the early stages of the viral cycle. Interestingly, BmKn2-T5 was also found to suppress the replication of the enveloped viruses DENV, ZIKV, and HSV-1 in the early stages of the viral cycle, which suggests they may share a common early infection step with EV71. Together, the results of our study identified that the scorpion-derived antimicrobial peptide BmKn2-T5 showed valuable antiviral properties against EV71 in vitro, but also against other enveloped viruses, making it a potential new candidate therapeutic molecule. Full article

This study aimed to identify potential BCL-2 small molecule inhibitors using deep neural networks (DNN) and random forest (RF) algorithms as well as molecular docking and molecular dynamics (MD) simulations to screen a library of small molecules. The RF model classified 61% (2355/3867) of molecules as ‘Active’. Further analysis through molecular docking with Vina identified CHEMBL3940231, CHEMBL3938023, and CHEMBL3947358 as top-scored small molecules with docking scores of −11, −10.9, and 10.8 kcal/mol, respectively. MD simulations validated these compounds’ stability and binding affinity to the BCL-2 protein. Full article

With the development of society, the demand for smart coatings is increasing. The development of flexible strain sensors using block copolymer self-assembled ionic gel materials provides a promising method for promoting the development of smart coatings. The ionic liquid in the ionic part of the material is crucial for the performance of the sensor. In this study, the structural changes within FDA/dEAN (self-assembly of acrylated Pluronic F127 (F127-DA) in partially deuterated ethylammonium nitrate (dEAN)) triblock copolymer ionic gel during uniaxial tensile flow were characterized using an in situ SAXS technique. The results revealed that the characteristics of the responses of the ionic gel to strain resistance were intricately linked to the evolution of its microstructure during the tensile process. At low levels of strain, the face-centered cubic lattice arrangement of the micelles tended to remain unchanged. However, when subjected to higher strains, the molecular chains aligned along the stretching direction, resulting in a more ordered structure with reduced entropy. This alignment led to significant disruption in bridging structures within the material. Furthermore, this research explored the impact of the stretching rate on the relaxation process. It was observed that higher stretching rates led to decreases in the average relaxation time, indicating rate dependence in the microstructure’s behavior. These findings provide valuable insights into the behavior and performance of flexible strain sensors based on ionic gel materials in smart coatings. Full article

Electrospark coatings alloyed with MoS₂ have been studied. The coatings were obtained by the following two strategies: the first consisted of pre-applying molybdenum disulfide to the treated surface and alloying with a molybdenum electrode (Mo + MoS₂ coating); the second consisted of applying a paste with a sulfur content of 33.3% to the treated surface and alloying with a molybdenum electrode (Mo + S coating). The structure, phase composition, and tribological properties of the coatings were investigated. The coatings have a complex structure consisting of an upper soft layer, a hardened white layer, a diffusion zone, and a substrate. Element analysis and cross-sectional hardness changes indicated that element diffusion occurred at the coating/substrate interface. The phase composition of the coatings is represented by BCC and FCC solid solutions on Fe, and MoS₂ is also detected. In Mo + S coatings, the molybdenum disulfide on the surface is about 8%; in Mo + MoS₂ coatings, it is 27%–46%. The obtained coatings show very good tribological properties compared to molybdenum ESA coatings. The frictional forces and coefficients are reduced by a factor of 10 and 40, depending on the test conditions. Full article

The frictional properties of lithium compound grease (LCG) with different percentage compositions of few-layer graphene (FLG) were investigated, and the mechanisms of temperature and loading effects on LCG containing FLG are also considered. The concluding effect shows that 1 wt% FLG is more appropriate for friction and wear modifiers for lithium compound grease at elevated temperatures and less suitable at ordinary temperatures. Thickener chemisorption film, FLG layering film, and tribo-reaction film consisting of FeO(OH), Fe₂O₃, Fe₃O₄, Li₂O, and other oxides assist in the establishment of a lubricating boundary film on the friction interfaces lubricated with LCG containing FLG. The poor fluidity of lithium compound grease at low temperatures leads to poor dispersion of FLG, decreasing friction reduction capability. Under elevated temperature and low load condition, adding 1wt% FLG to LCG can only improve its wear-resistant property, the abrasion volume of steel plate reduced by 24.49%. Under elevated temperature and high load condition, adding 1wt% FLG to LCG can only enhance its anti-friction characteristics.. Conversely, FLG is unsuitable as an anti-friction and wear-resistant additive for LCG at low-temperature conditions. Full article

Since it is difficult to study the influence of different defect characteristics on the stress intensity factor of B-type sleeve fillet welds via experiments, this paper adopts ABAQUS finite element analysis software(Version 2019) to model the B-type sleeve fillet welds and studies the stress and stress intensity factor under different crack lengths, heights, and angles. The simulation results showed that with the increase in crack length and depth, the maximum stress intensity factor gradually increased, and with the increase in the crack inclination angle, the maximum stress intensity factor first increased and then decreased. Full article

Anyuan Temple, constructed in the 29th year of the Qing Dynasty (1764), serves as a repository of numerous Sanskrit inscriptions and Hexi color paintings from the Qing era. Among its collections, the green Tara Buddha statue, exquisitely carved from wood, is recognized as a national first-class cultural relic. This edifice is instrumental in advancing our comprehension of painting artistry in royal temples. The current research focused on the pigments and binders utilized in the color paintings within Anyuan Temple, located in Chengde. An investigative process entailed collecting four samples from the paintings adorning the temple’s beams. These samples underwent comprehensive analysis using a variety of techniques, such as Scanning Electron Microscopy and Energy-Dispersive Spectrometry (EDS), Micro Raman Spectroscopy (m-RS), and X-ray Diffraction (XRD). The examination revealed that the paintings comprised pigments of lead white, cinnabar, malachite, and azurite, corresponding to the colors white, red, green, and blue, respectively. The enduring stability and aesthetic appeal of these pigments suggest their suitability for use in future conservation efforts. Additionally, Pyrolysis Gas Chromatography/Mass Spectrometry (Py-GC/MS) analysis identified animal glue as the binding agent in the wood component paintings. These insights are pivotal for the forthcoming restoration endeavors of Anyuan Temple, offering essential guidance in selecting the appropriate materials for restoration. Full article

In this study, the influence of W, Cr, and Mo on the microstructure and mechanical properties of the arc-welded interface of TiC cermet and low-carbon steel was investigated. MIG arc welding was employed to deposit muti-alloyed low-carbon steel flux-cored wire onto the surface of the TiC cermet to create the arc-welded interface. Analysis of the microstructure, phase composition, and shear fracture of the interface were conducted by OM (optical microscopy), SEM (scanning electron microscope), EMPA (Electron Probe X-ray Micro-Analyzer), and XRD (X-ray diffraction) methods. The results indicate that the order of influence on the performance of the welded interface is perceived as Cr > W > Mo. The preferred ratio of element content is W at 1.0 wt.%, Cr at 0.5 wt.%, and Mo at 2.0 wt.%. During the arc-welding process, W and Mo formed a rim structure of TiC particles to inhibit the dissolution of TiC particles, while Cr formed dispersed carbides in the bonding phase. The synergistic impact of these components resulted in the simultaneous enhancement of both the TiC particles and the bonding phase. This led to a significant increase in the shear strength of the TiC cermet welded interface to 787 MPa, marking an 83% improvement compared to the welded interface without reinforcement, which exhibited a shear strength of 430 MPa. Full article

In this paper, based on an Fe-based amorphous alloy, four kinds of RGO/Cu/Fe-based amorphous composite coatings with mass ratios of 5%, 10%, 15%, and 20% of RGO/Cu were prepared on the surface of 45# steel by using high-velocity oxy-fuel (HVOF) spraying. The coatings were immersed in simulated seawater at room temperature and at 90 °C for different lengths of time, and their corrosion resistance was tested using electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), and X-ray diffraction (XRD), and the surface morphology and phase distribution of the samples were observed. The results showed that with the increase in the introduction ratio of RGO/Cu, when the addition ratio reached 15%, the composite coating had the best corrosion resistance. After soaking in simulated seawater at 90 °C for 18 days, the surface of the coating showed slight peeling and crack propagation, but no obvious pitting phenomenon occurred. The corrosion mechanism of the RGO/Cu/Fe coating in high-temperature seawater is mainly that high temperature causes the cracking of the coating, which opens up a transport channel for corrosion media. However, due to the addition of RGO, the corrosion has a certain self-limitation effect, which is mainly due to the toughening effect of RGO on the coating and its effect on extending the corrosion channel. Full article

In this article, I consider how the epistemic problem of religious disagreement has been viewed within the Islamic tradition. Specifically, I consider two religious epistemological trends within the tradition: Islamic Rationalism and Islamic Traditionalism. In examining the approaches of both trends toward addressing the epistemic problem, I suggest that neither is wholly adequate. Nonetheless, I argue that both approaches offer insights that might be relevant to building a more adequate response. So, I attempt to combine insights from both by drawing a distinction between inferential and noninferential reflective responsibility. Given this distinction, I argue that it may be possible for a theist to remain steadfast in upholding their tradition-specific theistic belief, without having to hold that belief by way of inference; but nevertheless, having to be sufficiently reflectively responsible in forming their theistic belief noninferentially. Full article

Background: The occurrence of ventricular tachyarrhythmias represents an established risk factor of mortality in heart failure (HF). However, data concerning their prognostic impact in heart failure with mildly reduced ejection fraction (HFmrEF) is limited. Therefore, the present study aims to investigate patient characteristics associated with ventricular tachyarrhythmias and their prognostic impact in patients with HFmrEF. Methods: Consecutive patients hospitalized with HFmrEF (i.e., left ventricular ejection fraction 41–49% and signs and/or symptoms of HF) were retrospectively included at one institution from 2016 to 2022. The prognosis of patients with HFmrEF and different types of ventricular tachyarrhythmias (i.e., non-sustained ventricular tachycardia (nsVT), sustained VT (sVT), and ventricular fibrillation (VF) was investigated for the primary endpoint of long-term all-cause mortality at 30 months. Secondary endpoints included in-hospital all-cause mortality and long-term HF-related rehospitalization at 30 months. Results: From a total of 2184 patients with HFmrEF, 4.4% experienced ventricular tachyarrhythmias (i.e., 2.0% nsVT, 0.7% sVT, and 1.6% VF). The occurrence of nsVT was associated with higher New York Heart Association (NYHA) functional class, whereas the incidence of sVT/VF was associated with acute myocardial infarction and ischemic heart disease. However, nsVT (25.0%; HR = 0.760; 95% CI 0.419–1.380; p = 0.367) and sVT/VF (28.8%; HR = 0.928; 95% CI 0.556–1.549; p = 0.776) were not associated with a higher risk of long-term all-cause mortality compared to patients with HFmrEF without ventricular tachyarrhythmias (31.5%). In-hospital cardiovascular mortality was more frequently observed in patients with HFmrEF and sVT/VF compared to those with HFmrEF but without sustained ventricular tachyarrhythmias (7.7% vs. 1.5%; p = 0.004). Finally, the risk of rehospitalization for worsening HF was not affected by the presence of ventricular tachyarrhythmias. Conclusions: The occurrence of ventricular tachyarrhythmias in patients hospitalized with HFmrEF was low and not associated with long-term prognosis. Full article

A devastating earthquake took place on 8 April 1893, close to the town of Svilajnac, central Serbia. Over the past decade, significant historical data on the effects of this earthquake has been collected from a variety of sources, including books, scientific publications, reports, newspapers, and coeval chronicles. Additionally, this earthquake was recorded 750 km from the epicenter at the seismological station Rocca di Papa in Rome, Italy. Based on critical review and analysis of the historical data, we demonstrate that the epicentral area of this earthquake was 531 km², and the macroseismic effects were recorded at epicentral distances up to 600 km towards the west (Vienna, Austria) towards the north, up to 500 km (Košice–Michalovce, Slovakia), towards the east up to 460 km (Brašov–Borsec, Romania); and towards the south up to about 300 km (Radoviš, North Macedonia). Finally, we show that the key parameters of the 1893 Svilajnac earthquake are as follows: (1) epicentral intensity, I₀ = IX EMS-98, (2) the estimations of the moment magnitude and focal depth based on the observed intensities, M_W = 6.8 and h = 13 km, respectively, and (3) the epicenter coordinates, 44.160° N and 21.354° E. Full article

Background: School health education (SHE) serves as a primary pedagogical aspect of public health. This study aims to explore the curricula of preservice schoolteachers, examining whether graduate courses in Greek universities include SHE, how it is structured, and whether critical pedagogy principles are integrated. Methods: A corpus of n = 21 documents was compiled, encompassing all educational departments in Greek higher education, including Departments of Early Childhood Education and Care (n = 3), Departments of Preschool Education (n = 9), and Departments of Primary Education (n = 9). Results: Content analysis revealed the presence of SHE in 11 out of 21 educational departments. Thematic analysis uncovered significant variability in the curricula, with greater emphasis placed on health-related topics rather than the methodologies and values of SHE. Critical pedagogy principles were not explicitly evident in the curricula, while a persistent biomedical orientation left little room for the development of concepts related to social justice. Conclusions: This study represents the first of its kind in Greece and among the few internationally to examine preservice training for schoolteachers in SHE. The findings underscore the need for revisions to align with the key lessons learned from the major public health crisis of the COVID-19 pandemic. It is imperative to acknowledge that vulnerabilities have been exacerbated, and inequalities widened, necessitating a reassessment of current approaches to health education within teacher training programs. Full article

Valproic acid (VPA) is a common anti-epileptic drug and known neurodevelopmental toxicant. Although the exact mechanism of VPA toxicity remains unknown, recent findings show that VPA disrupts redox signaling in undifferentiated cells but has little effect on fully differentiated neurons. Redox imbalances often alter oxidative post-translational protein modifications and could affect embryogenesis if developmentally critical proteins are targeted. We hypothesize that VPA causes redox-sensitive post-translational protein modifications that are dependent upon cellular differentiation states. Undifferentiated P19 cells and P19-derived neurons were treated with VPA alone or pretreated with D3T, an inducer of the nuclear factor erythroid 2-related factor 2 (NRF2) antioxidant pathway, prior to VPA exposure. Undifferentiated cells treated with VPA alone exhibited an oxidized glutathione redox couple and increased overall protein oxidation, whereas differentiated neurons were protected from protein oxidation via increased S-glutathionylation. Pretreatment with D3T prevented the effects of VPA exposure in undifferentiated cells. Taken together, our findings support redox-sensitive post-translational protein alterations in undifferentiated cells as a mechanism of VPA-induced developmental toxicity and propose NRF2 activation as a means to preserve proper neurogenesis. Full article