The 2023 MDPI Annual Report has
been released!
 
18 pages, 1404 KiB  
Article
RoUIE: A Method for Constructing Knowledge Graph of Power Equipment Based on Improved Universal Information Extraction
by Zhenhao Ye, Donglian Qi, Hanlin Liu, Yunfeng Yan, Qihao Chen and Xiayu Liu
Energies 2024, 17(10), 2249; https://doi.org/10.3390/en17102249 (registering DOI) - 07 May 2024
Abstract
The current state evaluation of power equipment often focuses solely on changes in electrical quantities while neglecting basic equipment information as well as textual information such as system alerts, operation records, and defect records. Constructing a device-centric knowledge graph by extracting information from [...] Read more.
The current state evaluation of power equipment often focuses solely on changes in electrical quantities while neglecting basic equipment information as well as textual information such as system alerts, operation records, and defect records. Constructing a device-centric knowledge graph by extracting information from multiple sources related to power equipment is a valuable approach to enhance the intelligence level of asset management. Through the collection of pertinent authentic datasets, we have established a dataset for the state evaluation of power equipment, encompassing 35 types of relationships. To better suit the characteristics of concentrated relationship representations and varying lengths in textual descriptions, we propose a generative model called RoUIE, which is a method for constructing a knowledge graph of power equipment based on improved Universal Information Extraction (UIE). This model first utilizes a pre-trained language model based on rotational position encoding as the text encoder in the fine-tuning stage. Subsequently, we innovatively leverage the Distribution Focal Loss (DFL) to replace Binary Cross-Entropy Loss (BCE) as the loss function, further enhancing the model’s extraction performance. The experimental results demonstrate that compared to the UIE model and mainstream joint extraction benchmark models, RoUIE exhibits superior performance on the dataset we constructed. On a general Chinese dataset, the proposed model also outperforms baseline models, showcasing the model’s universal applicability. Full article
(This article belongs to the Section C: Energy Economics and Policy)
17 pages, 686 KiB  
Article
Encouraging Invasive Acacia Control Strategies by Repurposing Their Wood Biomass Waste for Pulp and Paper Production
by Duarte M. Neiva, Maria C. Godinho, Rogério M. S. Simões and Jorge Gominho
Forests 2024, 15(5), 822; https://doi.org/10.3390/f15050822 (registering DOI) - 07 May 2024
Abstract
Concerns on the expanding infestation of several Acacia species in the southern Mediterranean European countries have triggered an ever-growing requirement for costly targeted control actions. Valorizing biomass waste produced could help promote and better finance these actions. For that purpose, wood wastes from [...] Read more.
Concerns on the expanding infestation of several Acacia species in the southern Mediterranean European countries have triggered an ever-growing requirement for costly targeted control actions. Valorizing biomass waste produced could help promote and better finance these actions. For that purpose, wood wastes from invasive control actions were tested regarding their pulp and paper potential, aiming to entice cellulose industries to partake in future conservation actions. Wood waste from the five most pervasive Acacia species was studied (Acacia dealbata Link, Acacia longifolia Willd, Acacia mearnsii De Wild, Acacia melanoxylon R.Br, and Acacia saligna Labill) regarding physical and chemical characteristics, and a central composite design was used to optimize alkali charge and reaction temperature on pulping yield and delignification. Bleached kraft pulps were produced with each species’ optimized conditions and for an equitable mixture of all species. Optimized pulp yields (52.6%–53.5%) and pulp polymerization degree (2867–3690) of Acacia species were higher than those of Eucalyptus globulus Labill (used as reference). Optimized bleached pulps were refined and fiber, pulp, and handsheet properties determined. Acacia dealbata and A. longifolia presented high specific wood consumption and lower handsheet strength properties, pointing to overall lower pulping potential, while A. melanoxylon and A. mearnsii characteristics were equal to or higher than those of E. globulus. A. saligna pulp and handsheet characteristics appear more suited for tissue paper. The Acacia mixture achieved acceptable characteristics, enabling the indiscriminate use of Acacia wood regardless of the species. As a shortcoming, the Acacia pulps showed the worst optical characteristics, with brightness dropping substantially with beating (64%–76%) when compared to E. globulus (81%). Full article
(This article belongs to the Section Wood Science and Forest Products)
18 pages, 847 KiB  
Article
Basic Performance Evaluation of a Radiation Survey Meter That Uses a Plastic-Scintillation Sensor
by Keisuke Yamamoto, Ryota Shindo, Saya Ohno, Satoe Konta, Rio Isobe, Yohei Inaba, Masatoshi Suzuki, Yoshio Hosoi and Koichi Chida
Sensors 2024, 24(10), 2973; https://doi.org/10.3390/s24102973 (registering DOI) - 07 May 2024
Abstract
After the Fukushima nuclear power plant accident in 2011, many types of survey meters were used, including Geiger–Müller (GM) survey meters, which have long been used to measure β-rays. Recently, however, a novel radiation survey meter that uses a plastic-scintillation sensor has been [...] Read more.
After the Fukushima nuclear power plant accident in 2011, many types of survey meters were used, including Geiger–Müller (GM) survey meters, which have long been used to measure β-rays. Recently, however, a novel radiation survey meter that uses a plastic-scintillation sensor has been developed. Although manufacturers’ catalog data are available for these survey meters, there have been no user reports on performance. In addition, the performance of commercial plastic-scintillation survey meters has not been evaluated. In this study, we experimentally compared the performance of a plastic-scintillation survey meter with that of a GM survey meter. The results show that the two instruments performed very similarly in most respects. The GM survey meter exhibited count losses when the radiation count rate was high, whereas the plastic-scintillation survey meter remained accurate under such circumstances, with almost no count loss at high radiation rates. For measurements at background rates (i.e., low counting rates), the counting rates of the plastic-scintillation and GM survey meters were similar. Therefore, an advantage of plastic-scintillation survey meters is that they are less affected by count loss than GM survey meters. We conclude that the plastic-scintillation survey meter is a useful β-ray measuring/monitoring instrument. Full article
(This article belongs to the Section Physical Sensors)
11 pages, 1397 KiB  
Communication
Improving the Accuracy of Direction of Arrival Estimation with Multiple Signal Inputs Using Deep Learning
by Yihan Lu, Hengchao Guan, Kun Yang, Tong Peng, Chengyuan Wen and Xin Li
Sensors 2024, 24(10), 2971; https://doi.org/10.3390/s24102971 (registering DOI) - 07 May 2024
Abstract
In this paper, an innovative cyclic noise reduction method and an improved CAPON algorithm (also the called minimum variance distortionless response (MVDR) algorithm) are proposed to improve the accuracy and reliability of DOA (direction of arrival) estimation. By processing the eigenvalues obtained from [...] Read more.
In this paper, an innovative cyclic noise reduction method and an improved CAPON algorithm (also the called minimum variance distortionless response (MVDR) algorithm) are proposed to improve the accuracy and reliability of DOA (direction of arrival) estimation. By processing the eigenvalues obtained from the covariance matrix of the received signal, the signal-to-noise ratio (SNR) can be increased by up to 5 dB by the cyclic noise reduction method, which will improve the DOA estimation accuracy. The improved CAPON algorithm has a convolution neural network (CNN) structure, whose input is the processed covariance matrix of the received signal, and the CAPON spectral value is used as the training label to obtain the estimated spatial spectrum. It retains the advantages of the CAPON algorithm, which can achieve blind source estimation, and simulations show that the proposed algorithm exhibits a better performance than the traditional algorithm in conditions of various SNRs and snapshot numbers. The simulation results show that, based on a certain SNR, the root mean square error (RMSE) of the improved CAPON algorithm can be reduced from 0.86° to 0.8° compared to traditional algorithms, and the angle estimation error can be decreased by up to about 0.3°. With the help of the cyclic noise reduction method, the angle estimation error decreases from 0.04° to 0.02°. Full article
(This article belongs to the Special Issue Novel Antennas for Wireless Communication and Intelligent Sensing)
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17 pages, 5923 KiB  
Article
Shoulder Movement-Centered Measurement and Estimation Scheme for Underarm-Throwing Motions
by Geunho Lee, Yusuke Hayakawa, Takuya Watanabe and Yasuhiro Bonkobara
Sensors 2024, 24(10), 2972; https://doi.org/10.3390/s24102972 (registering DOI) - 07 May 2024
Abstract
Underarm throwing motions are crucial in various sports, including boccia. Unlike healthy players, people with profound weakness, spasticity, athetosis, or deformity in the upper limbs may struggle or find it difficult to control their hands to hold or release a ball using their [...] Read more.
Underarm throwing motions are crucial in various sports, including boccia. Unlike healthy players, people with profound weakness, spasticity, athetosis, or deformity in the upper limbs may struggle or find it difficult to control their hands to hold or release a ball using their fingers at the proper timing. To help them, our study aims to understand underarm throwing motions. We start by defining the throwing intention in terms of the launch angle of a ball, which goes hand-in-hand with the timing for releasing the ball. Then, an appropriate part of the body is determined in order to estimate ball-throwing intention based on the swinging motion. Furthermore, the geometric relationship between the movements of the body part and the release angle is investigated by involving multiple subjects. Based on the confirmed correlation, a calibration-and-estimation model that considers individual differences is proposed. The proposed model consists of calibration and estimation modules. To begin, as the calibration module is performed, individual prediction states for each subject are updated online. Then, in the estimation module, the throwing intention is estimated employing the updated prediction. To verify the effectiveness of the model, extensive experiments were conducted with seven subjects. In detail, two evaluation directions were set: (1) how many balls need to be thrown in advance to achieve sufficient accuracy; and (2) whether the model can reach sufficient accuracy despite individual differences. From the evaluation tests, by throwing 20 balls in advance, the model could account for individual differences in the throwing estimation. Consequently, the effectiveness of the model was confirmed when focusing on the movements of the shoulder in the human body during underarm throwing. In the near future, we expect the model to expand the means of supporting disabled people with ball-throwing disabilities. Full article
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11 pages, 1934 KiB  
Article
Essential Oil of Psidium glaziovianum Kiaersk Alleviates the Effects of Complete Freund’s Adjuvant (CFA)-Induced Arthritis by Regulating Inflammation and Oxidative Stress
by Wêndeo Kennedy Costa, João Victor de Oliveira Alves, Beatriz Meyruze Barros Da Fonseca, Valquíria Bruna Guimarães Silva, Rafael Jardim Ferreira, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva, Maria Tereza dos Santos Correia, Alisson Macário de Oliveira and Márcia Vanusa da Silva
Drugs Drug Candidates 2024, 3(2), 380-390; https://doi.org/10.3390/ddc3020023 (registering DOI) - 07 May 2024
Abstract
Rheumatoid arthritis (RA) is a chronic and debilitating condition that affects a significant number of individuals worldwide. Unfortunately, the currently available therapeutic approaches often yield unsatisfactory results and may be accompanied by harmful side effects. A medicinal plant called Psidium glaziovianum Kiaersk has [...] Read more.
Rheumatoid arthritis (RA) is a chronic and debilitating condition that affects a significant number of individuals worldwide. Unfortunately, the currently available therapeutic approaches often yield unsatisfactory results and may be accompanied by harmful side effects. A medicinal plant called Psidium glaziovianum Kiaersk has potential benefits in the treatment of this condition due to its anti-inflammatory and analgesic properties. In this study, our objective was to investigate the potential therapeutic effects of P. glaziovianum essential oil (PgEO) in alleviating arthritis symptoms in mice induced by Complete Freund’s Adjuvant (CFA). The effect of P. glaziovianum essential oil was evaluated in mice with Complete Freund’s Adjuvant (CFA)-induced arthritis. Edema sizes, macroscopic and radiographic images, cytokine levels, and oxidative stress were evaluated. Administration of PgEO at dosages of 50 and 100 mg/kg effectively prevented CFA-induced osteoarticular changes in arthritic mice, resulting in a significant reduction in joint damage. Additionally, the PgEO treatment exhibited the ability to minimize edema, a common symptom associated with arthritis. Furthermore, PgEO can modulate the levels of pro-inflammatory cytokines and oxidative stress, both of which play crucial roles in the progression of the disease. In conclusion, our study suggests that PgEO holds great potential as a natural therapeutic agent for rheumatoid arthritis. Full article
(This article belongs to the Section Preclinical Research)
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19 pages, 3224 KiB  
Article
Development of a Multiplexing Injector for Gas Chromatography for the Time-Resolved Analysis of Volatile Emissions from Lithium-Ion Batteries
by Maria Antoniadou, Valentin Schierer, Daniela Fontana, Jürgen Kahr and Erwin Rosenberg
Molecules 2024, 29(10), 2181; https://doi.org/10.3390/molecules29102181 (registering DOI) - 07 May 2024
Abstract
Multiplex sampling, so far mainly used as a tool for S/N ratio improvement in spectroscopic applications and separation techniques, has been investigated here for its potential suitability for time-resolved monitoring where chromatograms of transient signals are recorded at intervals much shorter than the [...] Read more.
Multiplex sampling, so far mainly used as a tool for S/N ratio improvement in spectroscopic applications and separation techniques, has been investigated here for its potential suitability for time-resolved monitoring where chromatograms of transient signals are recorded at intervals much shorter than the chromatographic runtime. Different designs of multiplex sample introduction were developed and utilized to analyze lithium-ion battery degradation products under normal or abuse conditions to achieve fast and efficient sample introduction. After comprehensive optimization, measurements were performed on two different GC systems, with either barrier discharge ionization detection (BID) or mass spectrometric detection (MS). Three different injector designs were examined, and modifications in the pertinent hardware components and operational conditions used. The shortest achievable sample introduction time was 50 ms with an interval of 6 s. Relative standard deviations were lower than 4% and 10% for the intra- and inter-day repeatability, respectively. The sample introduction system and column head pressure had to be carefully controlled, as this parameter most critically affects the amount of sample introduced and, thus, detector response. The newly developed sample introduction system was successfully used to monitor volatile degradation products of lithium-ion batteries and demonstrated concentration changes over the course of time of the degradation products (e.g., fluoroethane, acetaldehyde and ethane), as well as for solvents from the battery electrolyte like ethyl carbonate. Full article
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8 pages, 515 KiB  
Article
Comparing Entomology-Themed Outreach Events: Annual Festivals and Open Houses in the United States
by Stephanie Blevins Wycoff, Daniel L. Frank and Michael J. Weaver
Insects 2024, 15(5), 337; https://doi.org/10.3390/insects15050337 (registering DOI) - 07 May 2024
Abstract
Over the past several decades, there has been a growing prevalence of entomology-themed outreach events, which seek to educate the public about insects and other arthropods, fostering a greater appreciation and understanding of these often misunderstood organisms. In 2016, a comparative analysis was [...] Read more.
Over the past several decades, there has been a growing prevalence of entomology-themed outreach events, which seek to educate the public about insects and other arthropods, fostering a greater appreciation and understanding of these often misunderstood organisms. In 2016, a comparative analysis was initiated to identify science institutions across the United States engaged in providing annual entomology-themed outreach events to the public. Utilizing literature reviews and online searches, several science institutions were identified and subsequently contacted to partake in a survey regarding their events. The survey received a response rate of 93%. Results from the survey offered valuable insights into these entomology-themed outreach events, including records of attendance, event structures, funding sources, popular exhibits, and the impacts on attendees, hosting institutions, and local communities. While the majority of these events have remained in place since the survey, many have experienced significant disruptions due to the COVID-19 pandemic, prompting some to adapt to innovative online formats and virtual experiences. Despite these challenges, the commitment to entomological outreach continues today, highlighting the resilience and adaptability of the entomology community. Full article
(This article belongs to the Collection Cultural Entomology: Our Love-hate Relationship with Insects)
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11 pages, 231 KiB  
Article
Strategies for Integrating Generative AI into Higher Education: Navigating Challenges and Leveraging Opportunities
by Gila Kurtz, Meital Amzalag, Nava Shaked, Yanay Zaguri, Dan Kohen-Vacs, Eran Gal, Gideon Zailer and Eran Barak-Medina
Educ. Sci. 2024, 14(5), 503; https://doi.org/10.3390/educsci14050503 (registering DOI) - 07 May 2024
Abstract
The recent emergence of generative AI (GenAI) tools such as ChatGPT, Midjourney, and Gemini have introduced revolutionary capabilities that are predicted to transform numerous facets of society fundamentally. In higher education (HE), the advent of GenAI presents a pivotal moment that may profoundly [...] Read more.
The recent emergence of generative AI (GenAI) tools such as ChatGPT, Midjourney, and Gemini have introduced revolutionary capabilities that are predicted to transform numerous facets of society fundamentally. In higher education (HE), the advent of GenAI presents a pivotal moment that may profoundly alter learning and teaching practices in aspects such as inaccuracy, bias, overreliance on technology and algorithms, and limited access to educational AI resources that require in-depth investigation. To evaluate the implications of adopting GenAI in HE, a team of academics and field experts have co-authored this paper, which analyzes the potential for the responsible integration of GenAI into HE and provides recommendations about this integration. This paper recommends strategies for integrating GenAI into HE to create the following positive outcomes: raise awareness about disruptive change, train faculty, change teaching and assessment practices, partner with students, impart AI learning literacies, bridge the digital divide, and conduct applied research. Finally, we propose four preliminary scale levels of a GenAI adoption for faculty. At each level, we suggest courses of action to facilitate progress to the next stage in the adoption of GenAI. This study offers a valuable set of recommendations to decision-makers and faculty, enabling them to prepare for the responsible and judicious integration of GenAI into HE. Full article
23 pages, 606 KiB  
Article
A Green Supply Chain with Sales Effort under a Cost-Sharing Contract
by Jiayu Shen
Mathematics 2024, 12(10), 1435; https://doi.org/10.3390/math12101435 (registering DOI) - 07 May 2024
Abstract
Due to social and psychological factors, the COVID-19 pandemic has impacted international trade, dampened consumption globally, and resulted in conservative investment and spending. To stimulate economic recovery while promoting the establishment of a positive consumption awareness among people, enterprises endeavor to enhance competitiveness [...] Read more.
Due to social and psychological factors, the COVID-19 pandemic has impacted international trade, dampened consumption globally, and resulted in conservative investment and spending. To stimulate economic recovery while promoting the establishment of a positive consumption awareness among people, enterprises endeavor to enhance competitiveness and expand market share through various means, such as advertising and discounting. With more attention paid to environmentally friendly products, there are greater challenges encountered by green supply chain management. In this study, a green supply chain network problem is analyzed, involving a manufacturer and a retailer. In addition to the construction of centralized and decentralized decision models, two cost-sharing contracts are adopted to reduce promotion costs for the retailer and improve the level of greenery in products. With the help of game theory, equilibrium decisions can be made by solving the models. According to the results of numerical experiment, cost-sharing contracts can effectively improve the level of greenery in products and the profitability of the supply chain, despite the inability to achieve a win–win situation. Full article
22 pages, 2949 KiB  
Article
RNA-Seq Reveals That Multiple Pathways Are Involved in Tuber Expansion in Tiger Nuts (Cyperus esculentus L.)
by Guangshan Hou, Guojiang Wu, Huawu Jiang, Xue Bai and Yaping Chen
Int. J. Mol. Sci. 2024, 25(10), 5100; https://doi.org/10.3390/ijms25105100 (registering DOI) - 07 May 2024
Abstract
The tiger nut (Cyperus esculentus L.) is a usable tuber and edible oil plant. The size of the tubers is a key trait that determines the yield and the mechanical harvesting of tiger nut tubers. However, little is known about the anatomical [...] Read more.
The tiger nut (Cyperus esculentus L.) is a usable tuber and edible oil plant. The size of the tubers is a key trait that determines the yield and the mechanical harvesting of tiger nut tubers. However, little is known about the anatomical and molecular mechanisms of tuber expansion in tiger nut plants. This study conducted anatomical and comprehensive transcriptomics analyses of tiger nut tubers at the following days after sowing: 40 d (S1); 50 d (S2); 60 d (S3); 70 d (S4); 90 d (S5); and 110 d (S6). The results showed that, at the initiation stage of a tiger nut tuber (S1), the primary thickening meristem (PTM) surrounded the periphery of the stele and was initially responsible for the proliferation of parenchyma cells of the cortex (before S1) and then the stele (S2–S3). The increase in cell size of the parenchyma cells occurred mainly from S1 to S3 in the cortex and from S3 to S4 in the stele. A total of 12,472 differentially expressed genes (DEGs) were expressed to a greater extent in the S1–S3 phase than in S4–S6 phase. DEGs related to tuber expansion were involved in cell wall modification, vesicle transport, cell membrane components, cell division, the regulation of plant hormone levels, signal transduction, and metabolism. DEGs involved in the biosynthesis and the signaling of indole-3-acetic acid (IAA) and jasmonic acid (JA) were expressed highly in S1–S3. The endogenous changes in IAA and JAs during tuber development showed that the highest concentrations were found at S1 and S1–S3, respectively. In addition, several DEGs were related to brassinosteroid (BR) signaling and the G-protein, MAPK, and ubiquitin–proteasome pathways, suggesting that these signaling pathways have roles in the tuber expansion of tiger nut. Finally, we come to the conclusion that the cortex development preceding stele development in tiger nut tubers. The auxin signaling pathway promotes the division of cortical cells, while the jasmonic acid pathway, brassinosteroid signaling, G-protein pathway, MAPK pathway, and ubiquitin protein pathway regulate cell division and the expansion of the tuber cortex and stele. This finding will facilitate searches for genes that influence tuber expansion and the regulatory networks in developing tubers. Full article
(This article belongs to the Special Issue Formation, Regulation and Affecting Factors of Fruit Quality)
25 pages, 1568 KiB  
Article
Upgrade of the Universal Testing Machine for the Possibilities of Fatigue Tests in a Limited Mode
by Róbert Huňady, Peter Sivák, Ingrid Delyová, Jozef Bocko, Ján Vavro, Jr and Darina Hroncová
Appl. Sci. 2024, 14(10), 3973; https://doi.org/10.3390/app14103973 (registering DOI) - 07 May 2024
Abstract
The object of the upgrade presented in this paper was an older analogue-based universal testing machine preferably designed for tensile testing. The objective of the upgrade was to create a new digitized measurement chain capable of also operating in the mode of simple [...] Read more.
The object of the upgrade presented in this paper was an older analogue-based universal testing machine preferably designed for tensile testing. The objective of the upgrade was to create a new digitized measurement chain capable of also operating in the mode of simple fatigue tests with cyclic tensile stresses. The upgrade of the equipment mainly included the processes of calibration, creation of related calibration jigs, creation of transformation dependencies and digitization, creation or completion of missing parts of chain-signal conditioning modules, A/D converters, special jigs, etc., as elements of the experimental hardware. The degree of correctness of the calibration and of the transformation dependencies created was verified by regression analysis, and this was verified by simple correlation analysis. The correctness of the proposed modifications, was verified on the basis of the fatigue tests performed for cyclic loading. Thus, it was possible to design, develop and functionally verify a new measurement chain based on an older universal testing machine. Thus, a partially digitized pulsator was created for the possibility of fatigue testing in a technically or functionally limited mode, mainly for educational purposes as a temporary replacement for the order of magnitude more expensive commercially produced test systems. Full article
(This article belongs to the Special Issue Fatigue Strength of Machines and Systems)
11 pages, 431 KiB  
Article
Comorbidities, Treatment and Survival Rates of Chronic Thromboembolic Pulmonary Hypertension in a Regional Centre
by Razvan Adrian Bertici, Nicoleta Sorina Bertici, Amalia Ridichie and Ovidiu Fira-Mladinescu
J. Clin. Med. 2024, 13(10), 2754; https://doi.org/10.3390/jcm13102754 (registering DOI) - 07 May 2024
Abstract
Background/Objectives: Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by a multitude of underlying causes, treatment modalities and prognostic outcomes. Our aim was to evaluate the underlying causes, comorbidities and survival rates of CTEPH patients. Methods: A retrospective analysis was conducted regarding [...] Read more.
Background/Objectives: Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by a multitude of underlying causes, treatment modalities and prognostic outcomes. Our aim was to evaluate the underlying causes, comorbidities and survival rates of CTEPH patients. Methods: A retrospective analysis was conducted regarding the evolution of CTEPH patients confirmed by right heart catheterization under treatment with specific vasodilator medication in our centre between 2008 and 2023. Results: We treated 14 CTEPH patients, 78.57% female, 52.79 ± 13.64 years at inclusion, representing 11.29% of our pulmonary arterial hypertension registry. Initially, the distribution of patients’ NYHA class was II-14.28%, III-71.42% and IV-14.28%. In total, 71.42% of these patients were technically operable due to the central location of the thrombus, but 42.85% presented severe comorbidities and 28.57% refused the surgery or it was financially inaccessible. Only four patients were operated on by pulmonary endarterectomy (PEA). Unfortunately, all the post-PEA patients had persistent pulmonary hypertension and had to continue vasodilator treatment. Overall, 64.28% of patients had monotherapy, 21.42% double therapy and 14.28% triple therapy. Regarding underlying causes and comorbidities, we found the following incidences: 78.57% chronic venous insufficiency, 42.85% obesity, 35.71% thyroid disease, hypertension and hyperuricemia, 21.42% thrombophilia and ischemic heart disease, 14.28% atrial fibrillation, vasculitis and lung disease, and 14.28% neoplastic history and diabetes. Seven patients died (50%), six of whom were unoperated and one of whom was lost (abandoned the program). The survival rates at 1, 3, 5 and 7 years for unoperated patients were 100%, 58.3%, 29.2% and 29.2% versus 100%, 75%, 75% and 75% in post-PEA patients. Conclusions: CTEPH, marked by delayed diagnosis, multiple comorbidities and limited intervention options, requires proactive screening and comprehensive multimodal therapies, including PEA, to improve survival rates. Full article
(This article belongs to the Section Pulmonology)
11 pages, 669 KiB  
Systematic Review
The Use of Bone Wax in Hemostatic Control for Total Knee and Hip Arthroplasties: A Systematic Review
by Kenny Do, Benjamin Vachirakorntong, Eric Kawana, Jenifer Do, Thinh Dat Phan and Thinh Dai Phan
J. Clin. Med. 2024, 13(10), 2752; https://doi.org/10.3390/jcm13102752 (registering DOI) - 07 May 2024
Abstract
Background/Objectives: Blood loss can be a serious complication in patients undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA). Various methods are used by surgeons to achieve hemostatic control in these patients. Complications are associated with perioperative blood loss. In this systematic [...] Read more.
Background/Objectives: Blood loss can be a serious complication in patients undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA). Various methods are used by surgeons to achieve hemostatic control in these patients. Complications are associated with perioperative blood loss. In this systematic review, we examined the efficacy of using bone wax to control bleeding in patients undergoing THA and TKA. Methods: The PRISMA model was used to systematically identify and aggregate articles for this study. The PubMed and EMBASE databases were used to search individual studies that examined the use of bone wax in THA or TKA. After applying the search term “bone wax”, 2478 articles were initially identified. After inclusion and exclusion criteria were applied, three articles were aggregated for this systematic review. Results: The use of bone wax in THA and TKA decreased blood loss in patients undergoing these operations. Postoperative blood loss following surgery was lower in the bone wax groups compared to the control groups as well. Patients in the bone wax groups also required fewer blood transfusions than those who did not receive bone wax. Conclusions: Bone wax appears to be another modality that can be used by physicians to maintain hemostatic control in THA or TKA patients. Reduced blood loss and transfusion rates in surgery can increase patient outcomes. More studies are needed to examine the efficacy of bone wax in comparison with other hemostatic tools. Full article
(This article belongs to the Section Orthopedics)
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13 pages, 1039 KiB  
Article
Three-Dimensional Evaluation of Treatment Effects and Post-Treatment Stability of Maxillary Molar Intrusion Using Temporary Anchorage Devices in Open Bite Malocclusion
by Hiroki Ogura, Kento Numazaki, Toshihito Oyanagi, Masahiro Seiryu, Arata Ito, Takahiro Noguchi, Fumitoshi Ohori, Michiko Yoshida, Tomohiro Fukunaga, Hideki Kitaura and Itaru Mizoguchi
J. Clin. Med. 2024, 13(10), 2753; https://doi.org/10.3390/jcm13102753 (registering DOI) - 07 May 2024
Abstract
Background: We investigated treatment outcomes and post-treatment stability in 10 patients with an anterior open bite and nonsurgical orthodontics. Methods: The patients underwent maxillary molar intrusion using temporary anchorage devices (TADs) to deepen the overbite due to mandibular autorotation. Lateral cephalograms [...] Read more.
Background: We investigated treatment outcomes and post-treatment stability in 10 patients with an anterior open bite and nonsurgical orthodontics. Methods: The patients underwent maxillary molar intrusion using temporary anchorage devices (TADs) to deepen the overbite due to mandibular autorotation. Lateral cephalograms and dental cast models were obtained before treatment (T0), immediately after it (T1), and >1 year after it (T2). Skeletal and dental cephalometric changes and three-dimensional movements of the maxillary dentitions were evaluated. Results: At T0, cephalometric analysis indicated that patients had skeletal class I with tendencies for a class II jaw relationship and a skeletal open bite. During active treatment (T0 to T1), the maxillary first molar intruded by 1.6 mm, the mandibular first molar extruded by 0.3 mm, the Frankfort-mandibular plane angle decreased by 1.1°, and the overbite increased by 4.1 mm. Statistically significant changes were observed in the amount of vertical movement of the maxillary first molar, Frankfort-mandibular plane angle, and overbite. Three-dimensional (3D) dental cast analysis revealed that the maxillary first and second molars intruded, whereas the anterior teeth extruded, with the second premolar as an infection point. In addition, the maxillary molar was tipped distally by 2.9° and rotated distally by 0.91°. Statistically significant changes were observed in the amount of vertical movement of the central incisor, lateral incisor, canine and first molar, and molar angulation. From T1 to T2, no significant changes in cephalometric measurements or the 3D position of the maxillary dentition were observed. The maxillary and mandibular dentitions did not significantly change during post-treatment follow-up. Conclusions: Maxillary molar intrusion using mini-screws is an effective treatment for open bite correction, with the achieved occlusion demonstrating 3D stability at least 1 year after treatment. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
14 pages, 3023 KiB  
Article
Microplastic Volatile Organic Compounds Found within Chrysaora chesapeakei in the Patuxent River, Maryland
by Carol A. Smith, Santosh Mandal, Chunlei Fan and Saroj Pramanik
Microplastics 2024, 3(2), 250-263; https://doi.org/10.3390/microplastics3020015 (registering DOI) - 07 May 2024
Abstract
Microplastics are tangible particles of less than 0.2 inches in diameter that are ubiquitously distributed in the biosphere and accumulate in water bodies. During the east-coast hot summers (23–29 °C) of 2021 and 2022, June through September, we captured copious amounts of the [...] Read more.
Microplastics are tangible particles of less than 0.2 inches in diameter that are ubiquitously distributed in the biosphere and accumulate in water bodies. During the east-coast hot summers (23–29 °C) of 2021 and 2022, June through September, we captured copious amounts of the jellyfish Chrysaora chesapeakei, a predominant species found in the Patuxent River of the Chesapeake Bay in Maryland on the United States East Coast. We determined that their gelatinous bodies trapped many microplastics through fluorescent microscopy studies using Rhodamine B staining and Raman Spectroscopy. The chemical nature of the microplastics was detected using gas chromatography–mass spectroscopy headspace (SPME-GC-MS) and solvent extraction (GC-MS) methods through a professional commercial materials evaluation laboratory. Numerous plastic-affiliated volatile organic compounds (VOCs) from diverse chemical origins and their functional groups (alkanes, alkenes, acids, aldehydes, ketones, ethers, esters, and alcohols) along with other non-microplastic volatile organic compounds were observed. Our findings corroborate data in the available scientific literature, distinguishing our finding’s suitability. Full article
(This article belongs to the Special Issue Microplastics in Aquatic Enviroments)
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22 pages, 1030 KiB  
Article
Comparative Life-Cycle Assessment of Steel and GFRP Rebars for Procurement Sustainability in the Construction Industry
by Saad Al Omar and Abdelhakim Abdelhadi
Sustainability 2024, 16(10), 3899; https://doi.org/10.3390/su16103899 (registering DOI) - 07 May 2024
Abstract
This research examines the potential impact on the procurement sustainability of replacing steel rebars with Glass Fiber-Reinforced Polymer (GFRP) rebars in the construction industry, focusing on screed pre-cast hollow core topping in a project in the Kingdom of Saudi Arabia. A comparative life [...] Read more.
This research examines the potential impact on the procurement sustainability of replacing steel rebars with Glass Fiber-Reinforced Polymer (GFRP) rebars in the construction industry, focusing on screed pre-cast hollow core topping in a project in the Kingdom of Saudi Arabia. A comparative life cycle assessment (LCA) is conducted using One Click LCA (Version 0.26.0) software for cradle-to-grave analysis. The assessment covers various stages, including raw material extraction, manufacturing, transportation, usage, and recycling. The comprehensive LCA highlights GFRP rebars as a more sustainable alternative to steel, emitting 17% less CO2 equivalent (2e) per kilogram throughout its life cycle. Additionally, GFRP requires substantially less mass compared to steel, resulting in a dramatic reduction in CO2e emissions ranging from 77.89% to 85.26% across different spacing configurations in real-world construction scenarios, as presented in this research case study. These findings suggest that GFRP rebars offer a promising solution for reducing the environmental impact of construction activities while potentially yielding significant cost savings over the project’s life cycle. Integrating environmental considerations into material selection processes can prioritize sustainability without compromising performance or safety, contributing to a more sustainable future for the construction industry globally. Full article
16 pages, 2000 KiB  
Article
Real-Time Detection Technology of Corn Kernel Breakage and Mildew Based on Improved YOLOv5s
by Mingming Liu, Yinzeng Liu, Qihuan Wang, Qinghao He and Duanyang Geng
Agriculture 2024, 14(5), 725; https://doi.org/10.3390/agriculture14050725 (registering DOI) - 07 May 2024
Abstract
In order to solve low recognition of corn kernel breakage degree and corn kernel mildew degree during corn kernel harvesting, this paper proposes a real-time detection method for corn kernel breakage and mildew based on improved YOlOv5s, which is referred to as the [...] Read more.
In order to solve low recognition of corn kernel breakage degree and corn kernel mildew degree during corn kernel harvesting, this paper proposes a real-time detection method for corn kernel breakage and mildew based on improved YOlOv5s, which is referred to as the CST-YOLOv5s model algorithm in this paper. The method continuously obtains images through the discrete uniform sampling device of corn kernels and generates whole corn kernels, breakage corn kernels, and mildew corn kernel dataset samples. We aimed at the problems of high similarity of some corn kernel features in the acquired images and the low precision of corn kernel breakage and mildew recognition. Firstly, the CBAM attention mechanism is added to the backbone network of YOLOv5s to finely allocate and process the feature information, highlighting the features of corn breakage and mildew. Secondly, the pyramid pooling structure SPPCPSC, which integrates cross-stage local networks, is adopted to replace the SPPF in YOLOv5s. SPP and CPSC technologies are used to extract and fuse features of different scales, improving the precision of object detection. Finally, the original prediction head is converted into a transformer prediction head to explore the prediction potential with a multi-head attention mechanism. The experimental results show that the CST-YOLOv5s model has a significant improvement in the detection of corn kernel breakage and mildew. Compared with the original YOLOv5s model, the average precision (AP) of corn kernel breakage and mildew recognition increased by 5.2% and 7.1%, respectively, and the mean average precision (mAP) of all kinds of corn kernel recognition is 96.1%, and the frame rate is 36.7 FPS. Compared with YOLOv4-tiny, YOLOv6n, YOLOv7, YOLOv8s, and YOLOv9-E detection model algorithms, the CST-YOLOv5s model has better overall performance in terms of detection accuracy and speed. This study can provide a reference for real-time detection of breakage and mildew kernels during the harvesting process of corn kernels. Full article
(This article belongs to the Section Digital Agriculture)
18 pages, 426 KiB  
Article
Optimizing Attribute Reduction in Multi-Granularity Data through a Hybrid Supervised–Unsupervised Model
by Zeyuan Fan, Jianjun Chen, Hongyang Cui, Jingjing Song and Taihua Xu
Mathematics 2024, 12(10), 1434; https://doi.org/10.3390/math12101434 (registering DOI) - 07 May 2024
Abstract
Attribute reduction is a core technique in the rough set domain and an important step in data preprocessing. Researchers have proposed numerous innovative methods to enhance the capability of attribute reduction, such as the emergence of multi-granularity rough set models, which can effectively [...] Read more.
Attribute reduction is a core technique in the rough set domain and an important step in data preprocessing. Researchers have proposed numerous innovative methods to enhance the capability of attribute reduction, such as the emergence of multi-granularity rough set models, which can effectively process distributed and multi-granularity data. However, these innovative methods still have numerous shortcomings, such as addressing complex constraints and conducting multi-angle effectiveness evaluations. Based on the multi-granularity model, this study proposes a new method of attribute reduction, namely using multi-granularity neighborhood information gain ratio as the measurement criterion. This method combines both supervised and unsupervised perspectives, and by integrating multi-granularity technology with neighborhood rough set theory, constructs a model that can adapt to multi-level data features. This novel method stands out by addressing complex constraints and facilitating multi-perspective effectiveness evaluations. It has several advantages: (1) it combines supervised and unsupervised learning methods, allowing for nuanced data interpretation and enhanced attribute selection; (2) by incorporating multi-granularity structures, the algorithm can analyze data at various levels of granularity. This allows for a more detailed understanding of data characteristics at each level, which can be crucial for complex datasets; and (3) by using neighborhood relations instead of indiscernibility relations, the method effectively handles uncertain and fuzzy data, making it suitable for real-world datasets that often contain imprecise or incomplete information. It not only selects the optimal granularity level or attribute set based on specific requirements, but also demonstrates its versatility and robustness through extensive experiments on 15 UCI datasets. Comparative analyses against six established attribute reduction algorithms confirms the superior reliability and consistency of our proposed method. This research not only enhances the understanding of attribute reduction mechanisms, but also sets a new benchmark for future explorations in the field. Full article
(This article belongs to the Special Issue Mathematical and Computing Sciences for Artificial Intelligence)
11 pages, 733 KiB  
Article
Impact of Inducible Nitric Oxide Synthase Activation on Endothelial Behavior under Magnesium Deficiency
by Giorgia Fedele, Sara Castiglioni, Valentina Trapani, Isabella Zafferri, Marco Bartolini, Silvana M. Casati, Pierangela Ciuffreda, Federica I. Wolf and Jeanette A. Maier
Nutrients 2024, 16(10), 1406; https://doi.org/10.3390/nu16101406 (registering DOI) - 07 May 2024
Abstract
Endothelial dysfunction is a crucial event in the early pathogenesis of cardiovascular diseases and is linked to magnesium (Mg) deficiency. Indeed, in endothelial cells, low Mg levels promote the acquisition of a pro-inflammatory and pro-atherogenic phenotype. This paper investigates the mechanisms by which [...] Read more.
Endothelial dysfunction is a crucial event in the early pathogenesis of cardiovascular diseases and is linked to magnesium (Mg) deficiency. Indeed, in endothelial cells, low Mg levels promote the acquisition of a pro-inflammatory and pro-atherogenic phenotype. This paper investigates the mechanisms by which Mg deficiency promotes oxidative stress and affects endothelial behavior in human umbilical vascular endothelial cells (HUVECs). Our data show that low Mg levels trigger oxidative stress initially by increasing NAPDH oxidase activity and then by upregulating the pro-oxidant thioredoxin-interacting protein TXNIP. The overproduction of reactive oxygen species (ROS) activates NF-κB, leading to its increased binding to the inducible nitric oxide synthase (iNOS) promoter, with the consequent increase in iNOS expression. The increased levels of nitric oxide (NO) generated by upregulated iNOS contribute to disrupting endothelial cell function by inhibiting growth and increasing permeability. In conclusion, we provide evidence that multiple mechanisms contribute to generate a pro-oxidant state under low-Mg conditions, ultimately affecting endothelial physiology. These data add support to the notion that adequate Mg levels play a significant role in preserving cardiovascular health and may suggest new approaches to prevent or manage cardiovascular diseases. Full article
(This article belongs to the Section Micronutrients and Human Health)
22 pages, 1377 KiB  
Article
Active Fault-Locating Scheme for Hybrid Distribution Line Based on Mutation of Aerial-Mode Injected Pulse
by Zhuang Jiang, Xiangjun Zeng, Feng Liu, Kun Yu, Lanxi Bi and Youpeng Wang
Energies 2024, 17(10), 2248; https://doi.org/10.3390/en17102248 (registering DOI) - 07 May 2024
Abstract
Due to the overlap of initial traveling wave signals, the traveling wave propagation process in hybrid distribution lines is complicated to analyze. The most significant challenge posed by the traditional passive traveling wave-locating method for hybrid distribution lines lies in identifying the fault [...] Read more.
Due to the overlap of initial traveling wave signals, the traveling wave propagation process in hybrid distribution lines is complicated to analyze. The most significant challenge posed by the traditional passive traveling wave-locating method for hybrid distribution lines lies in identifying the fault section and distinguishing the reflected wave from the fault point or the hybrid connection points. Based on this approach, with the application of the aerial-mode component of the pulse signal generated at the fault point, a fault-section-identification and fault-locating scheme for hybrid distribution feeders with active pulse injection is proposed. When power in a line is cut after a single-to-line ground (SLG) fault occurs, the same pulse is injected into the three phases from the neutral point of the coupling capacitor bank to construct the zero-mode component, which propagates to the SLG fault three-phase asymmetrical point, producing an aerial-mode component that is reflected back to the first end of the line. With the application of the arrival time of an aerial-mode wavefront, it is simple to locate the SLG fault for arbitrary forms of hybrid lines. The simulation results confirm the feasibility of the fault-locating scheme under different feeders, different fault locations, and fault resistances. The results of the experiments confirm the high practical value of the proposed method. Full article
(This article belongs to the Section F: Electrical Engineering)
27 pages, 1842 KiB  
Article
Environmental Design on Site-Specific Energy Solidary Communities around Public High Schools in the Metropolitan Area of Naples (Italy)
by Roberto Bosco, Savino Giacobbe, Salvatore Losco, Louise Anna Mozingo and Renata Valente
Energies 2024, 17(10), 2247; https://doi.org/10.3390/en17102247 (registering DOI) - 07 May 2024
Abstract
Renewable energy communities (RECs) around photovoltaic systems on public buildings are optimal solutions to counter energy poverty, ensuring all stakeholders access to cheap, reliable, sustainable, and modern energy systems. As the neighborhood is the minimum suitable unit for the implementation of highly sustainable [...] Read more.
Renewable energy communities (RECs) around photovoltaic systems on public buildings are optimal solutions to counter energy poverty, ensuring all stakeholders access to cheap, reliable, sustainable, and modern energy systems. As the neighborhood is the minimum suitable unit for the implementation of highly sustainable settlements, this article discusses the potential and criticality of RECs at this scale in southern Italy. Starting with the concept of RECs, this study presents a methodology to size sustainable urban communities around school buildings. It integrates practical energy indicators with those defining performance in vegetation and water management. The impact of these factors is analyzed to identify the ideal community size in terms of energy efficiency, economic value, and social cohesion. An interactive scorecard ranks high school sites suitable for transformation into community hubs, taking into consideration the scale of substation distribution. The findings provide empirically validated operational guidelines and best practices to support the transition to smart, efficient, and socially inclusive communities. At the urban scale, the analysis evaluates different urban morphologies, microclimates, characteristics and density of buildings, and population around each assumed community hub. The study provides valuable guidance to local designers, planners, and administrators for the implementation of sustainable technologies by preparing a map of potential RECs. Full article
12 pages, 779 KiB  
Article
Tunable Unexplored Luminescence in Waveguides Based on D-A-D Benzoselenadiazoles Nanofibers
by Carlos Tardío, Esther Pinilla-Peñalver, Beatriz Donoso and Iván Torres-Moya
Nanomaterials 2024, 14(10), 822; https://doi.org/10.3390/nano14100822 (registering DOI) - 07 May 2024
Abstract
A set of novel Donor-Acceptor-Donor (D-A-D) benzoselenadiazole derivatives has been synthesized and crystallized in nanocrystals in order to explore the correlation between their chemical structure and the waveguided luminescent properties. The findings reveal that all crystals exhibit luminescence and active optical waveguiding, demonstrating [...] Read more.
A set of novel Donor-Acceptor-Donor (D-A-D) benzoselenadiazole derivatives has been synthesized and crystallized in nanocrystals in order to explore the correlation between their chemical structure and the waveguided luminescent properties. The findings reveal that all crystals exhibit luminescence and active optical waveguiding, demonstrating the ability to adjust their luminescence within a broad spectral range of 550–700 nm depending on the donor group attached to the benzoselenadiazole core. Notably, a clear relationship exists between the HOMO-LUMO energy gaps of each compound and the color emission of the corresponding optical waveguides. These outcomes affirm the feasibility of modifying the color emission of organic waveguides through suitable chemical functionalization. Importantly, this study marks the first utilization of benzoseleniadiazole derivatives for such purposes, underscoring the originality of this research. In addition, the obtention of nanocrystals is a key tool for the implementation of miniaturized photonic devices. Full article
(This article belongs to the Special Issue Photofunctional Nanomaterials and Nanostructures)

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