Natural extracts, such as those from the residues of the Olea europaea industry, offer an opportunity for use due to their richness in antioxidant compounds. These compounds can be incorporated into porous polymeric devices with huge potential for tissue engineering such as bone, cardiovascular, osteogenesis, or neural applications using supercritical CO₂. For this purpose, polymeric scaffolds of biodegradable poly(lactic-co-glycolic acid) (PLGA) and chitosan, generated in situ by foaming, were employed for the supercritical impregnation of ethanolic olive leaf extract (OLE). The influence of the presence of chitosan on porosity and interconnectivity in the scaffolds, both with and without impregnated extract, was studied. The scaffolds have been characterized by X-ray computed microtomography, scanning electron microscope, measurements of impregnated load, and antioxidant capacity. The expansion factor decreased as the chitosan content rose, which also occurred when OLE was used. Pore diameters varied, reducing from 0.19 mm in pure PLGA to 0.11 mm in the two experiments with the highest chitosan levels. The connectivity was analyzed, showing that in most instances, adding chitosan doubled the average number of connections, increasing it by a factor of 2.5. An experiment was also conducted to investigate the influence of key factors in the impregnation of the extract, such as pressure (10–30 MPa), temperature (308–328 K), and polymer ratio (1:1–9:1 PLGA/chitosan). Increased pressure facilitated increased OLE loading. The scaffolds were evaluated for antioxidant activity and demonstrated substantial oxidation inhibition (up to 82.5% under optimal conditions) and remarkable potential to combat oxidative stress-induced pathologies. Full article

Composites revolutionize material performance, fostering innovation and efficiency in diverse sectors. Elastomer-based polymeric composites are crucial for applications requiring superior mechanical strength and durability. Widely applied in automotives, aerospace, construction, and consumer goods, they excel under extreme conditions. Composites based on recycled rubber, fortified with reinforcing fillers, represent a sustainable material innovation by repurposing discarded rubber. The integration of reinforcing agents enhances the strength and resilience of this composite, and the recycled polymeric matrix offers an eco-friendly alternative to virgin elastomers, reducing their environmental impact. Devulcanized rubber, with inherently lower mechanical properties than virgin rubber, requires enhancement of its quality for reuse in a circular economy: considerable amounts of recycled tire rubber can only be applied in new tires if the property profile comes close to the one of the virgin rubber. To achieve this, model passenger car tire and whole tire rubber granulates were transformed into elastomeric composites through optimized devulcanization and blending with additional fillers like carbon black and silica–silane. These fillers were chosen as they are commonly used in tire compounding, but they lose their reactivity during their service life and the devulcanization process. Incorporation of 20% (w/w) additional filler enhanced the strength of the devulcanizate composites by up to 15%. Additionally, increased silane concentration significantly further improved the tensile strength, Payne effect, and dispersion by enhancing the polymer–filler interaction through improved silanization. Higher silane concentrations reduced elongation at break and increased crosslink density, as it leads to a stable filler–polymer network. The optimal concentration of a silica–silane filler system for a devulcanizate was found to be 20% silica with 3% silane, showing the best property profile. Full article

An experimental device fixed with a laser displacement sensor was assembled to investigate the rebound behaviors and damping mechanism of rubber balls prepared with ethylene-propylene-diene monomer (EPDM)/chlorinated butyl rubber (CIIR) blends. The result showed that a prediction model was proposed to characterize the damping capacity by using the rebound height of the rubber balls. The lower rebound height corresponded to better damping capacity. A modified equation relating to the rebound height has been obtained from the theoretical derivation on the basis of the dynamic mechanical analysis, showing that the rebound height was affected by the deformation frequency, the external excitation, and the nature of rubber blends. Furthermore, the energy dissipation rate (EDR), defined by the ratio of the height loss to the rebound time, was proposed to further characterize the damping capacity. The EDR value was shown to be highest for the pure CIIR and lowest for the pure EPDM, exhibiting a decreasing trend with the increase in EPDM content in the rubber blends. It can be expected that the damping capacity of the EPDM/CIIR blends decreases with the decrease in external excitation, the conclusion of which plays a key role in the formulation design of viscoelastic damping rubber materials. Full article

Understanding the relationship between the intake of sugars and diet quality can inform public health recommendations. This systematic review synthesized recent literature on associations between sugar intake and diet quality in generally healthy populations aged 2 years or older. We searched databases from 2010 to 2022 for studies of any design examining associations between quantified sugar intake in the daily diet and dietary indexes (DIs) or micronutrient intakes. Different sugar types and diet quality measures were analyzed separately. We converted DI results to Pearson’s r correlations and grouped indexes with or without a free or added sugar component to facilitate cross-study comparisons. Meta-analysis was deemed inappropriate. From 13,869 screened records, we included 27 cross-sectional studies. NUQUEST risk of bias ratings were neutral (n = 18 studies) or poor (n = 9), and strength of evidence by the GRADE approach was very low due to study design. Most studies reported negative associations for added and free sugars with diet quality indexes (r ranging from −0.13 to −0.42) and nutrients of public health concern (fiber, vitamin D, calcium, potassium), while associations with total sugars were mixed. Due to cross-sectional study designs, the clinical relevance of these findings is unclear. Prospective studies are needed to minimize confounding and inform causal relationships. Full article

Servicification in global value chains (GVCs) in emerging and developing Asian economies has become a trend recently. However, there have been no scientific studies to elucidate the mechanism of servicification in GVCs. To fill this gap, this study aims to investigate the involvement of service sectors in GVCs in Asian economies in terms of the quantitative interactions between service inputs and manufacturing exports and inputs and between service inputs and service exports. For this purpose, a panel vector-autoregressive model and the Trade in Value Added database of the Organization for Economic Cooperation and Development (OECD) were used for the empirical analysis during 1995–2018. The estimation results find that, first, there exist reciprocal interactions between the business services and manufacturing sectors; foreign business service inputs are induced by manufacturing exports, whereas manufacturing inputs are induced by business service exports. Second, foreign manufacturing inputs facilitate foreign business service inputs. Third, business service inputs are promoted by business service exports. These trends in the involvement of business services’ involvement in GVCs have accelerated since the mid-2000s. To enhance the role of services in GVCs, Asian economies should facilitate the removal of explicit restrictions in service trade and address regulatory divergence across countries. Full article

Organic–inorganic hybrids represent a good solution to improve the solubility and dissolution rates of poorly soluble drugs whose number has been increasing in the last few years. One of the most diffused inorganic matrices is hydroxyapatite (HAP), which is a biocompatible and osteoconductive material. However, the understanding of the hybrids’ functioning mechanisms is in many cases limited; thus, thorough physicochemical characterizations are needed. In the present paper, we prepared hybrids of pure and Mg-doped hydroxyapatite with meloxicam, a drug pertaining to the Biopharmaceutical Classification System (BCS) class II, i.e., drugs with low solubility and high permeability. The hybrids’ formation was demonstrated by FT-IR, which suggested electrostatic interactions between HAP and drug. The substitution of Mg in the HAP structure mainly produced a structural disorder and a reduction in crystallite sizes. The surface area of HAP increased after Mg doping from 82 to 103 m²g⁻¹ as well as the pore volume, justifying the slightly high drug amount adsorbed by the Mg hybrid. Notwithstanding the low drug loading on the hybrids, the solubility, dissolution profiles and wettability markedly improved with respect to the drug alone, particularly for the Mg doped one, which was probably due to the main distribution of the drug on the HAP surface. Full article

The increased seismic activity observed in the Himalayas, coupled with the expanding urbanization of the surrounding areas in northern India, poses significant risks to both human lives and property. Developing an earthquake early warning system in the region could help in alleviating these risks, especially benefiting cities and towns in mountainous and foothill regions close to potential earthquake epicenters. To address this concern, the government and the science and engineering community collaborated to establish the Uttarakhand State Earthquake Early Warning System (UEEWS). The government of Uttarakhand successfully launched this full-fledged operational system to the public on 4 August 2021. The UEEWS includes an array of 170 accelerometers installed in the seismogenic areas of the Uttarakhand. Ground motion data from these sensors are transmitted to the central server through the dedicated private telecommunication network 24 hours a day, seven days a week. This system is designed to issue warnings for moderate to high-magnitude earthquakes via a mobile app freely available for smartphone users and by blowing sirens units installed in the buildings earmarked by the government. The UEEWS has successfully issued alerts for light earthquakes that have occurred in the instrumented region and warnings for moderate earthquakes that have triggered in the vicinity of the instrumented area. This paper provides an overview of the design of the UEEWS, details of instrumentation, adaptation of attributes and their relation to earthquake parameters, operational flow of the system, and information about dissemination of warnings to the public. Full article

This paper explores the thermal behavior of multiple interface cracks situated between a half-plane and a thermal coating layer when subjected to transient thermal loading. The temperature distribution is analyzed using the hyperbolic heat conduction theory. In this model, cracks are represented as arrays of thermal dislocations, with densities calculated via Fourier and Laplace transformations. The methodology involves determining the temperature gradient within the uncracked region, and these calculations contribute to formulating a singular integral equation specific to the crack problem. This equation is subsequently utilized to ascertain the dislocation densities at the crack surface, which facilitates the estimation of temperature gradient intensity factors for the interface cracks experiencing transient thermal loading. This paper further explores how the relaxation time, loading parameters, and crack dimensions impact the temperature gradient intensity factors. The results can be used in fracture analysis of structures operating at high temperatures and can also assist in the selection and design of coating materials for specific applications, to minimize the damage caused by temperature loading. Full article

Aquaporins are membrane pores regulating the transport of water, glycerol, and other small molecules across membranes. Among 13 human aquaporins, six have been shown to transport H₂O₂ and are therefore called peroxiporins. Peroxiporins are implicated in cancer development and progression, partly due to their involvement in H₂O₂ transport. Oxidative stress is linked to breast cancer development but is also a mechanism of action for conventional chemotherapy. The aim of this study is to investigate the effects of prolonged oxidative stress on Aquaporin 3 (AQP3), Aquaporin 5 (AQP5), and signaling pathways in breast cancer cell lines of different malignancies alongside a non-tumorigenic breast cell line. The prolonged oxidative stress caused responses in viability only in the cancer cell lines, while it affected cell migration in the MCF7 cell line. Changes in the localization of NRF2, a transcription factor involved in oxidative stress response, were observed only in the cancer cell lines, and no effects were recorded on its downstream target proteins. Moreover, the prolonged oxidative stress caused changes in AQP3 and AQP5 expression only in the cancer cell lines, in contrast to their non-malignant counterparts. These results suggest peroxiporins are potential therapeutic targets in cancer treatment. However, further research is needed to elucidate their role in the modulation of therapy response, highlighting the importance of research on this topic. Full article

The experiment aimed to investigate the effects of plant polysaccharides combined with boric acid on digestive function, immune function and harmful gas and heavy metal contents in the faeces of fatteners. For this study, 90 healthy crossbred fatteners were selected and randomly divided into five groups: the control group was fed with a basal diet (Con); experimental group I was fed with basal diet + 40 mg/kg boric acid (BA); experimental group II was fed with basal diet + 40 mg/kg boric acid + 400 mg/kg Astragalus polysaccharides (BA+APS); experimental group III was fed with basal diet + 40 mg/kg boric acid + 200 mg/kg Ganoderma lucidum polysaccharides (BA+GLP); and experimental group IV was fed with basal diet + 40 mg/kg boric acid + 500 mg/kg Echinacea polysaccharides (BA+EPS). Compared with Con, the average daily gain (ADG), the trypsin activities in the duodenum and jejunum, the IL-2 levels in the spleen, the T-AOC activities and GSH-Px contents in the lymph node of fattening were increased in the BA group (p < 0.05), but malondialdehyde content in the lymph and spleen, and the contents of NH₃, H₂S, Hg, Cu, Fe and Zn in the feces and urine were decreased (p < 0.05). Compared with the BA, the ADG, gain-to-feed ratio (G/F), the trypsin and maltase activities in the duodenum and jejunum were increased in the BA+APS (p < 0.05), and the T-SOD activities in the spleen and T-AOC activities in the lymph node were also increased (p < 0.05), but the H₂S level was decreased in the feces and urine (p < 0.05). Compared with the BA, the ADG, G/F and the trypsin and maltase activities in the duodenum were increased in the BA+GLP and BA+EPS (p < 0.05), the activities of maltase and lipase in the duodenum of fatteners in the BA+GLP and the activities of trypsin, maltase and lipase in the BA+EPS were increased (p < 0.05). Gathering everything together, our findings reveal that the combined addition of boric acid and plant polysaccharides in the diet of fatteners synergistically improved their growth performance and immune status. That may be achieved by regulating the activity of intestinal digestive enzymes, improving the antioxidant function and then promoting the digestion and absorption of nutrients. Furthermore, the above results reduce the emission of harmful gases and heavy metals in feces and urine. Full article

The demand for Vaccinium fruits has skyrocketed due to their nutritional and medicinal properties, notably their high content of phenolic compounds and excellent sensory evaluation. The use of Vaccinium plants and its components as dietary supplements and health ingredients has been on the rise across the world. The attractive fruits contain a high content of anthocyanins and antioxidant compounds. In some popular and valuable cultivars, the conventional propagation methods, exploiting hard or soft wood cuttings, are inefficient. The demand for nursery plants can be fulfilled by micropropagation. This review aims to explore advances in the in vitro culture of Vaccinium plants, focusing on effective disinfection, optimized culture media, and the role of growth regulators in plant development and multiplication. By providing a controlled environment, micropropagation allows the large-scale production of these plants in a short time, ensuring availability throughout the year. Additionally, this technique offers the advantage of studying the effects of abiotic stresses on plants, as well as facilitating research on the production of relevant metabolites. This review seeks to provide an updated overview of the most promising methods and techniques for micropropagation of Vaccinium, thereby contributing to the ongoing development of the blueberry production industry and derivative products. Full article

Background and Objectives: The purpose of this study was to investigate whether early surfactant administration affects the status of ductus arteriosus (DA) in preterm infants ≤ 32 weeks of gestational age (GA) within 24 h of birth. Materials and Methods: It is a prospective study conducted from 1 March 2022 to 31 December 2023 in a tertiary academic center. In-born infants ≤ 32 weeks of gestation (n = 88) were enrolled. The study group was further divided into surfactant (n = 44) and non-surfactant (n = 44) subgroups. Results: A total of 76% of the preterm infants who received surfactant therapy (RRR = 0.839) recorded an increase in Kindler score at 24 h of life (1 − RR = 1 − 0.24 = 76%). Surfactant administration was significantly associated with decreased pre-ductal diastolic pressure (29.9 mmHg vs. 34.8 mmHg, p = 0.0231), post-ductal diastolic pressure (28.7 mmHg vs. 32.2 mmHg, p = 0.0178), pre-ductal MAP (41.6 mmHg vs. 46.5 mmHg, p = 0.0210), and post-ductal MAP (41.0 mmHg vs. 45.3 mmHg, p = 0.0336). There were no significant changes in ductus arteriosus parameters at 24 h of life. Conclusions: Early surfactant administration does not affect the status of ductus arteriosus in preterm infants ≤ 32 weeks of gestational age at 24 h of life. Full article

Mast cells (MCs) are tissue-resident immune cells distributed in all tissues and strategically located close to blood and lymphatic vessels and nerves. Thanks to the expression of a wide array of receptors, MCs act as tissue sentinels, able to detect the presence of bacteria and parasites and to respond to different environmental stimuli. MCs originate from bone marrow (BM) progenitors that enter the circulation and mature in peripheral organs under the influence of microenvironment factors, thus differentiating into heterogeneous tissue-specific subsets. Even though MC activation has been traditionally linked to IgE-mediated allergic reactions, a role for these cells in other pathological conditions including tumor progression has recently emerged. However, several aspects of MC biology remain to be clarified. The advent of single-cell RNA sequencing platforms has provided the opportunity to understand MCs’ origin and differentiation as well as their phenotype and functions within different tissues, including the gut. This review recapitulates how single-cell transcriptomic studies provided insight into MC development as well as into the functional role of intestinal MC subsets in health and disease. Full article

As a geological barrier for high-level radioactive waste (HLW) disposal in China, granite is crucial for blocking nuclide migration into the biosphere. However, the high uncertainty associated with the 3D geological system, such as the stochastic discrete fracture networks in granite, significantly impedes practical safety assessments of HLW disposal. This study proposes a Monte Carlo simulation (MCS)-based simulation framework for evaluating the long-term barrier performance of nuclide migration in fractured rocks. Statistical data on fracture geometric parameters, on-site hydrogeological conditions, and relevant migration parameters are obtained from a research site in Northwestern China. The simulation models consider the migration of three key nuclides, Cs-135, Se-79, and Zr-93, in fractured granite, with mechanisms including adsorption, advection, diffusion, dispersion, and decay considered as factors. Subsequently, sixty MCS realizations are performed to conduct a sensitivity analysis using the open-source software OpenGeoSys-5 (OGS-5). The results reveal the maximum and minimum values of the nuclide breakthrough time T_t (12,000 and 3600 years, respectively) and the maximum and minimum values of the nuclide breakthrough concentration C_max (4.26 × 10⁻⁴ mSv/a and 2.64 × 10⁻⁵ mSv/a, respectively). These significant differences underscore the significant effect of the uncertainty in the discrete fracture network model on long-term barrier performance. After the failure of the waste tank (1000 years), nuclides are estimated to reach the outlet boundary 6480 years later. The individual effective dose in the biosphere initially increases and then decreases, reaching a peak value of C_max = 4.26 × 10⁻⁴ mSv/a around 350,000 years, which is below the critical dose of 0.01 mSv/a. These sensitivity analysis results concerning nuclide migration in discrete fractured granite can enhance the simulation and prediction accuracy for risk evaluation of HLW disposal. Full article

Damping reduction factors (DRFs) play a vital role in the seismic design of structures. DRFs have been widely studied due to their primary importance to the lateral resistance of structures subjected to earthquakes. On the other hand, devastating earthquakes have occurred all over the world, and recently, the Kahramanmaraş earthquakes in Turkey revealed the import of the vertical component of earthquakes and their impact on structures and infrastructures. Considering the importance of this parameter, this paper aims to develop new damping reduction factor (DRF) equations for the acceleration (DRFa), velocity (DRFv), and displacement spectra (DRFd) of the vertical components of earthquakes. For this purpose, 775 real ground motion records were selected from the Pacific Earthquake Engineering Research (PEER) strong motion database, and the vertical elastic response spectra of selected records were computed according to linear dynamic analysis. Taking the 5%-damped vertical response spectra as the target, the vertical spectral damping reduction factors (DRFa, DRFv, and DRFd) were computed for 1%, 3%, 10%, 15%, 20%, 30%, and 40% damping ratios. The effect of the earthquake magnitude, distance, and soil types on the DRFs was investigated. The results indicated that magnitude, distance, and soil type had no particular effect on the trend in the DRFs. Based on the evaluations, extensive statistical analyses were carried out, and new prediction equations were developed according to the nonlinear regression method. The developed equations were then compared to those found in the literature and seismic design codes. The comparisons proved that the proposed DRFa, DRFd, and DRFv models are strongly compatible with real DRFs and show strong robustness compared to existing models. Full article

Skin aging is an unavoidable natural phenomenon caused by intrinsic and extrinsic factors. In modern society, the pursuit of a wrinkle-free and aesthetically appealing face has gained considerable prominence. Numerous studies have aimed at mitigating the appearance of facial wrinkles. Antiaging research focused on regulating the function of mitochondria, the main reactive oxygen species-generating organelles, has been extensively conducted. In this study, we investigated the correlation between facial wrinkles and the expression of PPARGC1B, considering the association of this gene with mitochondrial function, to identify its potential as a target for exploring antiaging cosmetic materials. We elucidated the role of PPARGC1B in the skin and identified five bioactive materials that modulated its expression. The effectiveness of these materials was verified through in vitro experiments on human dermal fibroblasts. We prepared cosmetic formulations incorporating the five materials and confirmed their ability to enhance dermal collagen in three-dimensional skin models and reduce facial wrinkles under the eyes and nasolabial fold areas in human subjects. The study findings have significant implications for developing novel antiaging cosmetic formulations by reinforcing mitochondrial functions. Full article

Jordan faces significant, immediate challenges of enhancing energy security while mitigating greenhouse gas emissions. One of the most promising approaches to achieve sustainable development, energy security, and environmental conservation is to increase the integration of renewable energy into electricity generation. To this end, the Jordanian government aims to expand investments in the green energy sector, with solar and wind energy expected to play a crucial role in meeting energy demands and promoting environmental sustainability. This paper aims to examine the distinct dynamics, challenges, obstacles, and potential solutions related to establishing community solar and wind farms in suburban areas of Jordan. It seeks to highlight the opportunities and barriers influencing the adoption of sustainable energy in the country. Evaluation results from engaging 320 key stakeholders were obtained through a questionnaire, and after comprehensive analysis, it became evident that the benefits and positive aspects of solar and wind farms outweigh their drawbacks and obstacles. These insights can be useful in guiding policies and practices to make renewable energy community projects a reality within Jordan’s suburban areas. Additionally, the findings may serve as a valuable benchmark for other regions facing similar challenges in their pursuit of a sustainable energy future. Full article

Background: Sleep is a complex phenomenon that affects several aspects of life, including cognitive functioning, emotional regulation, and overall well-being. Sleep disturbances, especially during adolescence, can negatively impact emotional regulation, making it a critical factor in targeting psychopathology. Methods: This study explores the interplay between emotional dysregulation (ED) and sleep patterns in a sample of 90 adolescent patients by means of self- and parent-rated clinical measures. Results: Our findings reveal a bidirectional relationship between ED and sleep problems. Adolescents with higher affective instability experience poorer sleep quality, while those with worse sleep quality exhibit higher internalizing problems. Additionally, emotional reactivity is associated with disrupted circadian rhythms. Conclusions: These results emphasize the significance of addressing sleep problems in the context of psychopathology treatment, potentially leading to improved outcomes. Further research is needed to determine the most effective treatment strategies, including nonpharmacological and pharmacological interventions. Understanding the intricate relationship between sleep problems and emotion regulation offers insights for more targeted and effective treatment approaches for youths struggling with ED. Full article

Tatton–Brown–Rahman syndrome is a rare autosomal dominant hereditary disease caused by pathogenic variants in the DNMT3A gene, which is an important participant in epigenetic regulation, especially during embryonic development, and is highly expressed in all tissues. The main features of the syndrome are high growth, macrocephaly, intellectual disability, and facial dysmorphic features. We present a clinical case of Tatton–Brown–Rahman syndrome in a ten-year-old boy with macrocephaly with learning difficulties, progressive eye impairment, and fatigue suspected by a deep learning-based diagnosis assistance system, Face2Gene. The proband underwent whole-exome sequencing, which revealed a recurrent nonsense variant in the 12th exon of the DNMT3A, leading to the formation of a premature stop codon—NM_022552.5:c.1443C>A (p.Tyr481Ter), in a heterozygous state. This variant was not found in parents, confirming its de novo status. The patient case described here contributes to the understanding of the clinical diversity of Tatton–Brown–Raman syndrome with a mild clinical presentation that expands the phenotypic spectrum of the syndrome. We report the first recurrent nonsense variant in the DNMT3A gene, suggesting a mutational hot-spot. Differential diagnoses of this syndrome with Sotos syndrome, Weaver syndrome, and Cowden syndrome, as well as molecular confirmation, are extremely important, since the presence of certain types of pathogenic variants in the DNMT3A gene significantly increases the risk of developing acute myeloid leukemia. Full article

Ischemia-reperfusion injury (IRI) during liver transplantation has been implicated in the recurrence of hepatocellular carcinoma (HCC). This systematic review aimed to evaluate interventions to reduce IRI during liver transplantation for HCC and their impact on oncologic outcomes. A comprehensive literature search retrieved four retrospective studies involving 938 HCC patients, utilising interventions such as post-operative prostaglandin administration, hypothermic machine perfusion, and normothermic machine perfusion. Overall, treated patients exhibited reduced post-operative hepatocellular injury and inflammation and significantly enhanced recurrence-free survival. Despite these promising results, the impact of these interventions on overall survival remains unclear. This underscores the imperative for further prospective research to comprehensively understand the efficacy of these interventions in HCC patients undergoing transplantation. The findings highlight the potential benefits of these strategies while emphasising the need for continued investigation into their overall impact. Full article

The aim of this study is to predict the distribution of temperature at various positions on silver-coated firefighter protective clothing when subjected to external radiant heat flux. This will be helpful in the determination of thermal protective performance. Firefighter clothing consists of three layers, i.e., the outer shell, moisture barrier and thermal liner. The outer shell is the exposed surface, which was coated with silver particles through a physical vapor deposition process called magnetron sputtering. Afterwards, these uncoated and silver-coated samples were exposed to radiant heat transmission equipment at 10 kW/m² as per the ISO 6942 standard. Silver-coated samples displayed better thermal protective performance as the rate of temperature rise in silver-coated samples slowed. Later, a numerical approach was employed, contemplating the impact of metallic coating on the exterior shell. The finite difference method was utilized for solving partial differential equations and the implicit method was employed to discretize the partial differential equations. The numerical model displayed a good prediction of the distribution of temperature at different nodes with respect to time. The comparison of time vs. temperature graphs at different nodes for uncoated and silver-coated samples acquired from numerical solutions showed similar patterns, as witnessed in the experimental results. Full article

Indoor location services often use Bluetooth low energy (BLE) devices for their low energy consumption and easy implementation. Applications like device monitoring, ranging, and asset tracking utilize the received signal strength (RSS) of the BLE signal to estimate the proximity of a device from the receiver. However, in multipath environments, RSS-based solutions may not provide an accurate estimation. In such environments, receivers with antenna arrays are used to calculate the difference in time of flight (ToF) and therefore calculate the direction of arrival (DoA) of the Bluetooth signal. Other techniques like triangulation have also been used, such as having multiple transmitters or receivers as a network of sensors. To find a lost item, devices like Tile^© use an onboard beeper to notify users of their presence. In this paper, we present a system that uses a single-measurement device and describe the method of measurement to estimate the location of a BLE device using RSS. A BLE device is configured as an Eddystone beacon for periodic transmission of advertising packets with RSS information. We developed a smartphone application to read RSS information from the beacon, designed an algorithm to estimate the DoA, and used the phone’s internal sensors to evaluate the DoA with respect to true north. The proposed measurement method allows for asset tracking by iterative measurements that provide the direction of the beacon and take the user closer at every step. The receiver application is easily deployable on a smartphone, and the algorithm provides direction of the beacon within a 30° range, as suggested by the provided results. Full article