The 2023 MDPI Annual Report has
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18 pages, 14758 KiB  
Article
Object Detection in Hazy Environments, Based on an All-in-One Dehazing Network and the YOLOv5 Algorithm
by Aijuan Li, Guangpeng Xu, Wenpeng Yue, Chuanyan Xu, Chunpeng Gong and Jiaping Cao
Electronics 2024, 13(10), 1862; https://doi.org/10.3390/electronics13101862 (registering DOI) - 10 May 2024
Abstract
This study introduces an advanced algorithm for intelligent vehicle target detection in hazy conditions, aiming to bolster the environmental perception capabilities of autonomous vehicles. The proposed approach integrates a hybrid convolutional module (HDC) into an all-in-one dehazing network, AOD-Net, to expand the perceptual [...] Read more.
This study introduces an advanced algorithm for intelligent vehicle target detection in hazy conditions, aiming to bolster the environmental perception capabilities of autonomous vehicles. The proposed approach integrates a hybrid convolutional module (HDC) into an all-in-one dehazing network, AOD-Net, to expand the perceptual domain for image feature extraction and refine the clarity of dehazed images. To accelerate model convergence and enhance generalization, the loss function has been optimized. For practical deployment in intelligent vehicle systems, the ShuffleNetv2 lightweight network module is incorporated into the YOLOv5s network backbone, and the feature pyramid network (FPN) within the neck network has been refined. Additionally, the network employs a global shuffle convolution (GSconv) to balance accuracy with parameter count. To further focus on the target, a convolutional block attention module (CBAM) is introduced, which helps in reducing the network’s parameter count without compromising accuracy. A comparative experiment was conducted, and the results indicated that our algorithm achieved an impressive mean average precision (mAP) of 76.8% at an intersection-over-union (IoU) threshold of 0.5 in hazy conditions, outperforming YOLOv5 by 7.4 percentage points. Full article
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11 pages, 577 KiB  
Review
Chalcones—Features, Identification Techniques, Attributes, and Application in Agriculture
by Magdalena Dziągwa-Becker, Marta Oleszek, Sylwia Zielińska and Wiesław Oleszek
Molecules 2024, 29(10), 2247; https://doi.org/10.3390/molecules29102247 (registering DOI) - 10 May 2024
Abstract
This review article is a comprehensive and current overview on chalcones, covering their sources, identification methods, and properties with a particular focus on their applications in the agricultural sector. The widespread use of synthetic pesticides has not only led to increased resistance among [...] Read more.
This review article is a comprehensive and current overview on chalcones, covering their sources, identification methods, and properties with a particular focus on their applications in the agricultural sector. The widespread use of synthetic pesticides has not only led to increased resistance among weeds and pests, resulting in economic losses, but it has also raised significant health concerns due to the overuse of these chemicals. In line with the European Green Deal 2030 and its Farm to Fork strategy, there is a targeted 50% reduction in the use of chemical pesticides by 2030, emphasizing a shift towards natural alternatives that are more environmentally sustainable and help in the restoration of natural resources. Chalcones and their derivatives, with their herbicidal, fungicidal, bactericidal, and antiviral properties, appear to be ideal candidates. These naturally occurring compounds have been recognized for their beneficial health effects for many years and have applications across multiple areas. This review not only complements the previous literature on the agricultural use of chalcones but also provides updates and introduces methods of detection such as chromatography and MALDI technique. Full article
16 pages, 5534 KiB  
Article
LDPC-Net: A Lightweight Detail–Content Progressive Coupled Network for Single-Image Dehazing with Adaptive Feature Extraction Block
by Lingrui Dai, Hongrui Liu and Shuoshi Li
Electronics 2024, 13(10), 1867; https://doi.org/10.3390/electronics13101867 (registering DOI) - 10 May 2024
Abstract
Image dehazing is an effective means to enhance the quality of images captured in foggy or hazy weather conditions. However, the existing dehazing methods either cannot obtain satisfactory recovery results or have large model parameters. This limits the application of the model on [...] Read more.
Image dehazing is an effective means to enhance the quality of images captured in foggy or hazy weather conditions. However, the existing dehazing methods either cannot obtain satisfactory recovery results or have large model parameters. This limits the application of the model on resource-limited platforms. To overcome these limitations, we propose a lightweight yet effective image-dehazing method, named the lightweight detail–content progressive coupled network (LDPC-Net). Within the framework of LDPC-Net, we propose a progressive coupling dehazing paradigm. Specifically, we first estimate the details and content information of the haze-free image, and then fuse these estimations using the progressive coupling method. This proposed dehazing framework markedly enhances the operational efficiency of the model. Meanwhile, considering both the effectiveness and efficiency of the network, we also design a lightweight adaptive feature extraction block serving as the basic feature extraction module of the proposed LDPC-Net. Extensive experimental results demonstrate the effectiveness of our LDPC-Net, outperforming the state-of-the-art methods by boosting the PSNR index over 38.57 dB with only 0.708 M parameters. Full article
21 pages, 1372 KiB  
Article
The Agro-Pastoral Transitional Zone in Northern China: Continuously Intensifying Land Use Competition Leading to Imbalanced Spatial Matching of Ecological Elements
by Kaige Wang, Xiangyu Zhao, Huihui Zheng, Bangyou Zheng, Yan Xu, Fengrong Zhang and Zengqiang Duan
Land 2024, 13(5), 654; https://doi.org/10.3390/land13050654 (registering DOI) - 10 May 2024
Abstract
The agro-pastoral transitional zone (APTZ) in northern China is a typical ecologically vulnerable zone and a comprehensive geographical transitional zone. Its land use pattern has significant type diversity and spatial interlocking, which is always related to the play of ecological barrier functions and [...] Read more.
The agro-pastoral transitional zone (APTZ) in northern China is a typical ecologically vulnerable zone and a comprehensive geographical transitional zone. Its land use pattern has significant type diversity and spatial interlocking, which is always related to the play of ecological barrier functions and the sustainability of social-ecological systems. Accurately grasping the spatial competition relationship and comprehensive geographical effects of land types of APTZ in northern China is a key proposition for achieving coordinated and sustainable development between humans and land. To explore the spatial competition mechanism and comprehensive geographical effects of land use in the research area, this study focuses on revealing the evolutionary characteristics of land use patterns based on the center of gravity migration model. Based on the process of land use center of gravity migration, the spatial competition relationship of land types is explored to reveal the evolutionary trend and basic characteristics of land use in the APTZ. The results show the following: (1) Cultivated land and meadow are the main land types of the APTZ in northern China, accounting for up to 70% of the total regional area. The spatial competition between the two land types is the main contradiction in regional land use competition. (2) Drifting of the center of gravity of cultivated land towards the northwest direction is an important land use migration feature of the APTZ in northern China. Between 1980 and 2020, the center of gravity of cultivated land shifted by about 2 km to the northwest, and the center of gravity of grassland shifted by 8–10 km to the southwest. (3) The center of gravity of arable land and grassland in the entire region is constantly approaching, which has decreased from 70.95 km in 1980 to 61.38 km in 2020. The intensification of their interweaving has led to more intense land use competition. Grasping the basic characteristics and driving mechanisms of land type competition is an important means to achieve sustainable spatial governance. (4) The scale differentiation and regional differentiation characteristics of gradient effects are significant, and it is essential to prevent the risk of mismatch between land use and natural endowments in the northeast and north China sections. The research has surpassed the traditional method of analyzing land use competition, and by introducing a centroid model to analyze the spatial mechanism of land use competition, it has expanded the methodology for expanding research in the field of land science and provided basic references for regional sustainable development. Full article
13 pages, 675 KiB  
Review
Hox Gene Collinearity with Pulling Physical Forces Creates a Hox Gene Clustering in Embryos of Vertebrates and Invertebrates: Complete or Split Clusters
by Spyros Papageorgiou
Symmetry 2024, 16(5), 594; https://doi.org/10.3390/sym16050594 (registering DOI) - 10 May 2024
Abstract
Hox gene clusters are crucial in embryogenesis. It was observed that some Hox genes are located in order along the telomeric to centromeric direction of the DNA sequence: Hox1, Hox2, Hox3…. These genes are expressed in the same order in the ontogenetic units [...] Read more.
Hox gene clusters are crucial in embryogenesis. It was observed that some Hox genes are located in order along the telomeric to centromeric direction of the DNA sequence: Hox1, Hox2, Hox3…. These genes are expressed in the same order in the ontogenetic units of the Drosophila embryo along the anterior–posterior axis. The two entities (genome and embryo) differ significantly in linear size and in-between distance. This strange phenomenon was named spatial collinearity (SP). Later, it was observed that, particularly in the vertebrates, a temporal collinearity (TC) coexists: first Hox1 is expressed, later Hox2, and later on Hox3…. According to a biophysical model (BM), pulling forces act at the anterior end of the cluster while a cluster fastening applies at the posterior end. Hox clusters are irreversibly elongated along the force direction. During evolution, the elongated Hox clusters are broken at variable lengths, thus split clusters may be created. An empirical rule was formulated, distinguishing development due to a complete Hox cluster from development due to split Hox clusters. BM can explain this empirical rule. In a spontaneous mutation, where the cluster fastening is dismantled, a weak pulling force automatically shifts the cluster inside the Hox activation domain. This cluster translocation can probably explain the absence of temporal collinearity in Drosophila. Full article
(This article belongs to the Special Issue Symmetry/Asymmetry in Life Sciences: Feature Papers 2024)
10 pages, 588 KiB  
Review
Relapse Prevention in Acute Myeloid Leukemia: The Role of Immunotherapy with Histamine Dihydrochloride and Low-Dose Interleukin-2
by Pau Montesinos, Francesco Buccisano, Thomas Cluzeau, Lovisa Vennström and Michael Heuser
Cancers 2024, 16(10), 1824; https://doi.org/10.3390/cancers16101824 (registering DOI) - 10 May 2024
Abstract
The treatment and management of acute myeloid leukemia (AML) has improved in recent decennia by targeted therapy for subgroups of patients, expanded indications for allogeneic stem cell transplantation (allo-SCT) and surveillance of residual or arising leukemia. However, hematological relapse among patients who have [...] Read more.
The treatment and management of acute myeloid leukemia (AML) has improved in recent decennia by targeted therapy for subgroups of patients, expanded indications for allogeneic stem cell transplantation (allo-SCT) and surveillance of residual or arising leukemia. However, hematological relapse among patients who have attained complete remission (CR) after the initial courses of chemotherapy remains a significant cause of morbidity and mortality. Here, we review an immunotherapeutic option using histamine dihydrochloride and low-dose interleukin-2 (HDC/LD-IL-2) for remission maintenance in AML. The treatment is approved in Europe in the post-consolidation phase to avoid relapse among patients in CR who are not candidates for upfront allo-SCT. We present aspects of the purported anti-leukemic mechanism of this regimen, including translation of preclinical results into the clinical setting, along with relapse prevention in subgroups of patients. We consider that HDC/LD-IL-2 is a conceivable option for younger adults, in particular patients with AML of normal karyotype and those with favorable responses to the initial chemotherapy. HDC/LD-IL-2 may form an emerging landscape of remission maintenance in AML. Full article
18 pages, 564 KiB  
Article
Effects of Soils on Environmental Stability of Spent Mg-Based and Ca-Based Adsorbents Containing Arsenite
by Hajime Sugita, Kazuya Morimoto, Takeshi Saito and Junko Hara
Sustainability 2024, 16(10), 4008; https://doi.org/10.3390/su16104008 (registering DOI) - 10 May 2024
Abstract
Spent adsorbents used in As removal treatment may re-leach As. In this study, the effects of soil on spent Mg-based and Ca-based adsorbents were investigated. The spent adsorbents containing arsenite (As(III)) were prepared by adsorbing As(III) on MgO, Mg(OH)2, CaO, and [...] Read more.
Spent adsorbents used in As removal treatment may re-leach As. In this study, the effects of soil on spent Mg-based and Ca-based adsorbents were investigated. The spent adsorbents containing arsenite (As(III)) were prepared by adsorbing As(III) on MgO, Mg(OH)2, CaO, and Ca(OH)2 powder reagents. Kuroboku soil (Ku), yellow-brown forest soil (YF), Kanuma soil (Ka), river sand (RS), and mountain sand (MS) were used as soil samples. The As leaching ratio was examined in coexistence with soil via shaking tests, and the results were compared with those of a previous study on adsorbents containing arsenate (As(V)). The environmental stability of the spent adsorbents was found to vary greatly depending on the combination of the As valence, adsorbent type, and soil type. However, regardless of the adsorbent or soil type, the spent adsorbents containing As(III) were more likely to leach As than those containing As(V). Additionally, the As leaching ratio was generally lower in Ku and YF and higher in Ka, RS, and MS. For environmentally friendly and sustainable As removal treatment, disposal, and management, the selection of MgO as the adsorbent and treatment involving the oxidation treatment of As(III) to As(V) before adsorbing As onto adsorbents are recommended. Full article
(This article belongs to the Section Pollution Prevention, Mitigation and Sustainability)
12 pages, 1346 KiB  
Article
Investigating Distinct Skin Microbial Communities and Skin Metabolome Profiles in Atopic Dermatitis
by Suyeon Kim, Minah Cho, Eun Sung Jung, Inseon Sim and Yu Ri Woo
Int. J. Mol. Sci. 2024, 25(10), 5211; https://doi.org/10.3390/ijms25105211 (registering DOI) - 10 May 2024
Abstract
Atopic dermatitis (AD) is a chronic inflammatory skin disorder influenced by genetic predisposition, environmental factors, immune dysregulation, and skin barrier dysfunction. The skin microbiome and metabolome play crucial roles in modulating the skin’s immune environment and integrity. However, their specific contributions to AD [...] Read more.
Atopic dermatitis (AD) is a chronic inflammatory skin disorder influenced by genetic predisposition, environmental factors, immune dysregulation, and skin barrier dysfunction. The skin microbiome and metabolome play crucial roles in modulating the skin’s immune environment and integrity. However, their specific contributions to AD remain unclear. We aimed to investigate the distinct skin microbial communities and skin metabolic compounds in AD patients compared to healthy controls (HCs). Seven patients with AD patients and seven HCs were enrolled, from whom skin samples were obtained for examination. The study involved 16S rRNA metagenomic sequencing and bioinformatics analysis as well as the use of gas chromatography time-of-flight mass spectrometry (GC-TOF-MS) to detect metabolites associated with AD in the skin. We observed significant differences in microbial diversity between lesional and non-lesional skin of AD patients and HCs. Staphylococcus overgrowth was prominent in AD lesions, while Cutibacterium levels were decreased. Metabolomic analysis revealed elevated levels of several metabolites, including hypoxanthine and glycerol-3-phosphate in AD lesions, indicating perturbations in purine metabolism and energy production pathways. Moreover, we found a positive correlation between hypoxanthine and glycerol-3-phosphate and clinical severity of AD and Staphylococcus overgrowth. These findings suggest potential biomarkers for monitoring AD severity. Further research is needed to elucidate the causal relationships between microbial dysbiosis, metabolic alterations, and AD progression, paving the way for targeted therapeutic interventions. Full article
(This article belongs to the Special Issue Molecular Research Progress of Skin and Skin Diseases)
12 pages, 415 KiB  
Article
Nutrition Messaging by Healthcare Students: A Mixed-Methods Study Exploring Social Media Usage and Digital Competence
by Hüsna Kaya Kaçar, Ömer Furkan Kaçar and Fiona McCullough
Nutrients 2024, 16(10), 1440; https://doi.org/10.3390/nu16101440 (registering DOI) - 10 May 2024
Abstract
Aim: The COVID-19 pandemic leads to a significant digital transformation in higher education and healthcare practices. This study aimed to investigate the level of digital competence, views and experiences, social media usage, and perceived barriers to digital communication among healthcare students. Method: Employing [...] Read more.
Aim: The COVID-19 pandemic leads to a significant digital transformation in higher education and healthcare practices. This study aimed to investigate the level of digital competence, views and experiences, social media usage, and perceived barriers to digital communication among healthcare students. Method: Employing a mixed-methods approach, quantitative data were gathered through an online survey, while qualitative insights were gleaned from semi-structured questionnaire responses obtained during focus group discussions. A total of 143 nursing and midwifery students from Turkey, along with 54 dietetics students from various European countries, participated in the study. Results: A significant proportion of nursing (43.5%) and midwifery (55.2%) students advocated for integrating digital technology training into university curricula. Instagram has emerged as the predominant platform for sharing healthcare/nutrition information among students. However, concerns have been raised regarding the prevalence of “before/after” posts on social media promoting weight loss, which were identified as low-quality content by participants. Conclusions: These findings underscore the importance of integrating digital technologies and social media into healthcare, nutrition education, and practice. Additionally, there is a pressing need to establish professional and ethical standards for digital nutritional communication. By addressing these challenges, educators can better equip healthcare students to navigate the complexities of modern healthcare practices and enhance patient-care outcomes. Full article
(This article belongs to the Special Issue Digital Transformations in Nutrition)
17 pages, 966 KiB  
Article
Predicting Alloying Element Yield in Converter Steelmaking Using t-SNE-WOA-LSTM
by Xin Liu, Xihui Qu, Xinjun Xie, Sijun Li, Yanping Bao and Lihua Zhao
Processes 2024, 12(5), 974; https://doi.org/10.3390/pr12050974 (registering DOI) - 10 May 2024
Abstract
The performance and quality of steel products are significantly impacted by the alloying element control. The efficiency of alloy utilization in the steelmaking process was directly related to element yield. This study analyses the factors that influence the yield of elements in the [...] Read more.
The performance and quality of steel products are significantly impacted by the alloying element control. The efficiency of alloy utilization in the steelmaking process was directly related to element yield. This study analyses the factors that influence the yield of elements in the steelmaking process using correlation analysis. A yield prediction model was developed using a t-distributed stochastic neighbor embedding (t-SNE) algorithm, a whale optimization algorithm (WOA), and a long short-term memory (LSTM) neural network. The t-SNE algorithm was used to reduce the dimensionality of the original data, while the WOA optimization algorithm was employed to optimize the hyperparameters of the LSTM neural network. The t-SNE-WOA-LSTM model accurately predicted the yield of Mn and Si elements with hit rates of 71.67%, 96.67%, and 99.17% and 57.50%, 89.17%, and 97.50%, respectively, falling within the error range of ±1%, ±2%, and ±3% for Mn and ±1%, ±3%, and ±5% for Si. The results demonstrate that the t-SNE-WOA-LSTM model outperforms the backpropagation (BP), LSTM, and WOA-LSTM models in terms of prediction accuracy. The model was applied to actual production in a Chinese plant. The actual performance of the industrial application is within a ±3% error range, with an accuracy of 100%. Furthermore, the elemental yield predicted by the model and then added the ferroalloys resulted in a reduction in the elemental content of the product by 0.017%. The model enables accurate prediction of alloying element yields and was effectively applied in industrial production. Full article
(This article belongs to the Section Energy Systems)
20 pages, 32920 KiB  
Article
Expert–Novice Level Classification Using Graph Convolutional Network Introducing Confidence-Aware Node-Level Attention Mechanism
by Tatsuki Seino, Naoki Saito, Takahiro Ogawa, Satoshi Asamizu and Miki Haseyama
Sensors 2024, 24(10), 3033; https://doi.org/10.3390/s24103033 (registering DOI) - 10 May 2024
Abstract
In this study, we propose a classification method of expert–novice levels using a graph convolutional network (GCN) with a confidence-aware node-level attention mechanism. In classification using an attention mechanism, highlighted features may not be significant for accurate classification, thereby degrading classification performance. To [...] Read more.
In this study, we propose a classification method of expert–novice levels using a graph convolutional network (GCN) with a confidence-aware node-level attention mechanism. In classification using an attention mechanism, highlighted features may not be significant for accurate classification, thereby degrading classification performance. To address this issue, the proposed method introduces a confidence-aware node-level attention mechanism into a spatiotemporal attention GCN (STA-GCN) for the classification of expert–novice levels. Consequently, our method can contrast the attention value of each node on the basis of the confidence measure of the classification, which solves the problem of classification approaches using attention mechanisms and realizes accurate classification. Furthermore, because the expert–novice levels have ordinalities, using a classification model that considers ordinalities improves the classification performance. The proposed method involves a model that minimizes a loss function that considers the ordinalities of classes to be classified. By implementing the above approaches, the expert–novice level classification performance is improved. Full article
(This article belongs to the Section Intelligent Sensors)
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17 pages, 2876 KiB  
Article
Potential of Plantain Pseudostems (Musa AAB Simmonds) for Developing Biobased Composite Materials
by Juan Pablo Castañeda-Niño, Jose Herminsul Mina Hernandez and Jose Fernando Solanilla Duque
Polymers 2024, 16(10), 1357; https://doi.org/10.3390/polym16101357 (registering DOI) - 10 May 2024
Abstract
A plantain pseudostem was harvested and processed on the same day. The process began with manually separating the sheaths (80.85%) and the core (19.14%). The sheaths were subjected to a mechanical shredding process using paddles, extracting 2.20% of lignocellulosic fibers and 2.12% of [...] Read more.
A plantain pseudostem was harvested and processed on the same day. The process began with manually separating the sheaths (80.85%) and the core (19.14%). The sheaths were subjected to a mechanical shredding process using paddles, extracting 2.20% of lignocellulosic fibers and 2.12% of sap, compared to the fresh weight of the sheaths. The fibers were washed, dried, combed, and spun in their native state and subjected to a steam explosion treatment, while the sap was subjected to filtration and evaporation. In the case of the core, it was subjected to manual cutting, drying, grinding, and sieving to separate 12.81% of the starch and 6.39% of the short lignocellulosic fibers, compared to the fresh weight of the core. The surface modification method using steam explosion succeeded in removing a low proportion of hemicellulose and lignin in the fibers coming from the shims, according to what was shown by Fourier Transform Infrared Spectroscopy (FT-IR), Thermogravimetric Analysis (TGA), and Differential Scanning Calorimetry (DSC), achieving increased σmax and ε from the tensile test and greater thermal stability compared to its native state. The sap presented hygroscopic behavior by FT-IR and the highest thermal stability from TGA, while the starch from the core presented the lowest hygroscopic character and thermal stability. Although the pseudostem supplied two types of fibers, lower lignin content was identified in those from the core. Finally, the yarns were elaborated by using the fibers of the sheaths in their native and steam-exploded states, identifying differences in the processing and their respective physical and mechanical properties. Full article
(This article belongs to the Special Issue Preparation and Application of Biomass-Based Materials)
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13 pages, 2398 KiB  
Article
Prediction Technology of a Reservoir Development Model While Drilling Based on Machine Learning and Its Application
by Xin Wang, Min Mao, Yi Yang, Shengbin Yuan, Mingyu Guo, Hongru Li, Leli Cheng, Heng Wang and Xiaobin Ye
Processes 2024, 12(5), 975; https://doi.org/10.3390/pr12050975 (registering DOI) - 10 May 2024
Abstract
In order to further understand the complex spatial distribution caused by the extremely strong heterogeneity of buried hill reservoirs, this paper proposes a new method for predicting the development pattern of buried hill reservoirs based on the traditional pre-drilling prediction and post-drilling evaluation [...] Read more.
In order to further understand the complex spatial distribution caused by the extremely strong heterogeneity of buried hill reservoirs, this paper proposes a new method for predicting the development pattern of buried hill reservoirs based on the traditional pre-drilling prediction and post-drilling evaluation methods that mainly rely on seismic, logging, and core data, which are difficult to meet the timeliness and accuracy of drilling operations. Firstly, the box method and normalization formula are used to process and normalize the abnormal data of element logging and engineering logging, and then the stepwise regression analysis method is used to optimize the sensitive parameters of element logging and engineering logging. The Light Gradient Boosting Machine (LightGBM) algorithm, deep neural network (DNN), and support vector machine (SVM) are used to establish a new method for predicting the development pattern of buried hill reservoirs. Lastly, a comprehensive evaluation index F1 score for the model is established to evaluate the prediction model for the development pattern of buried hill reservoirs. The F1 score value obtained from this model’s comprehensive evaluation index indicates that the LightGBM model achieves the highest accuracy, with 96.7% accuracy in identifying weathered zones and 95.8% accuracy in identifying interior zones. The practical application demonstrates that this method can rapidly and accurately predict the development mode of buried hill reservoirs while providing a new approach for efficient on-site exploration and decision-making in oil and gas field developments. Consequently, it effectively promotes exploration activities as well as enhances the overall process of oil and gas reservoir exploration. Full article
14 pages, 448 KiB  
Article
Development of a Predictive Model for Skin-to-Skin Contact Immediately after Birth: A Cross-Sectional Study
by María Antonia Díaz-Ogallar, Antonio Hernández-Martínez, Manuel Linares-Abad and Juan Miguel Martínez-Galiano
Children 2024, 11(5), 577; https://doi.org/10.3390/children11050577 (registering DOI) - 10 May 2024
Abstract
The aim of this study was to develop and validate a predictive model for the establishment of skin-to-skin contact immediately after birth. A descriptive cross-sectional study was conducted during the last trimester of 2022 and the first trimester of 2023 with women [...] Read more.
The aim of this study was to develop and validate a predictive model for the establishment of skin-to-skin contact immediately after birth. A descriptive cross-sectional study was conducted during the last trimester of 2022 and the first trimester of 2023 with women who had given birth in Spain. A questionnaire containing sociodemographic, psychosocial, and health variables referring to the mother and the newborn, as well as the Bond and Attachment questionnaire (VAMF, for its name in Spanish) for the analysis of the mother–child bond and attachment, were administered. A multivariate analysis was performed, and areas under the ROC curve (AUC) with their 95% confidence intervals (CI) and the predictive characteristics of these models were estimated. In total, 1077 women participated. The prevalence of early skin-to-skin contact after delivery was 50.2% (468) in the derivation cohort and 49.8% (464) in the validation cohort. Multivariate analysis showed that prematurity, type of delivery, and birth experience were statistically significant, so they were included in the model (p ≤ 0.05). The predictive ability (AUC ROC) was good in both the derivation cohort, yielding 0.92 (95% CI: 0.89–0.95), and in the validation cohort, yielding 0.89 (95% CI: 0.85–0.93). This study developed a predictive model identifying factors facilitating early skin-to-skin contact between a mother and her newborn immediately after birth. Full article
18 pages, 1215 KiB  
Review
Crystal-Inspired Cellular Metamaterials and Triply Periodic Minimal Surfaces
by Maxim Arsentev, Eduard Topalov, Sergey Balabanov, Evgenii Sysoev, Igor Shulga, Marsel Akhmatnabiev, Maxim Sychov, Ekaterina Skorb and Michael Nosonovsky
Biomimetics 2024, 9(5), 285; https://doi.org/10.3390/biomimetics9050285 (registering DOI) - 10 May 2024
Abstract
Triply periodic minimal surfaces (TPMSs) are found in many natural objects including butterfly wings, sea urchins, and biological membranes. They simultaneously have zero mean curvature at every point and a crystallographic group symmetry. A metamaterial can be created from such periodic surfaces or [...] Read more.
Triply periodic minimal surfaces (TPMSs) are found in many natural objects including butterfly wings, sea urchins, and biological membranes. They simultaneously have zero mean curvature at every point and a crystallographic group symmetry. A metamaterial can be created from such periodic surfaces or used as a reinforcement of a composite material. While a TPMS as a mathematical object has been known since 1865, only novel additive manufacturing (AM) technology made it possible to fabricate cellular materials with complex TPMS shapes. Cellular TPMS-based metamaterials have remarkable properties related to wetting/liquid penetration, shock absorption, and the absence of stress concentrators. Recent studies showed that TPMSs are also found in natural crystals when electron surfaces are considered. Artificial crystal-inspired metamaterials mimic such crystals including zeolites and schwarzites. These metamaterials are used for shock, acoustic waves, and vibration absorption, and as structural materials, heat exchangers, and for other applications. The choice of the crystalline cell of a material, as well as its microstructure, plays a decisive role in its properties. The new area of crystal-inspired materials has many common features with traditional biomimetics with models being borrowed from nature and adjusted for engineering applications. Full article
13 pages, 35214 KiB  
Article
Optimization of Mechanical Properties and Evaluation of Fatigue Behavior of Selective Laser Sintered Polyamide-12 Components
by David Sommer, Henry Stockfleet and Ralf Hellmann
Polymers 2024, 16(10), 1366; https://doi.org/10.3390/polym16101366 (registering DOI) - 10 May 2024
Abstract
In this paper, a comprehensive study of the mechanical properties of selective laser sintered polyamide components is presented, for various different process parameters as well as environmental testing conditions. For the optimization of the static and dynamic mechanical load behavior, different process parameters, [...] Read more.
In this paper, a comprehensive study of the mechanical properties of selective laser sintered polyamide components is presented, for various different process parameters as well as environmental testing conditions. For the optimization of the static and dynamic mechanical load behavior, different process parameters, e.g., laser power, scan speed, and build temperature, were varied, defining an optimal parameter combination. First, the influence of the different process parameters was tested, leading to a constant energy density for different combinations. Due to similarities in mechanical load behavior, the energy density was identified as a decisive factor, mostly independent of the input parameters. Thus, secondly, the energy density was varied by the different parameters, exhibiting large differences for all levels of fatigue behavior. An optimal parameter combination of 18 W for the laser power and a scan speed of 2666 mm/s was determined, as a higher energy density led to the best results in static and dynamic testing. According to this, the variation in build temperature was investigated, leading to improvements in tensile strength and fatigue strength at higher build temperatures. Furthermore, different ambient temperatures during testing were evaluated, as the temperature-dependent behavior of polymers is of high importance for industrial applications. An increased ambient temperature as well as active cooling during testing was examined, having a significant impact on the high cycle fatigue regime and on the endurance limit. Full article
(This article belongs to the Special Issue Mechanical and Physical Properties of 3D Printed Polymer Materials)
17 pages, 956 KiB  
Article
BMFA-Net: Boundary Constraint Multi-Level Feature Aggregation Framework for Precise Polyp Segmentation
by Qin Li, Tianchi Zhang, Parvej Md Mosharaf and Jing Zhang
Appl. Sci. 2024, 14(10), 4063; https://doi.org/10.3390/app14104063 (registering DOI) - 10 May 2024
Abstract
Colorectal cancer is one of the three most common cancers worldwide. Polyps are complex and have unclear boundaries, often leading to inaccurate boundary segmentation and missed detections. To address these challenges, we propose a boundary constraint multi-level feature aggregation framework called BMFA-Net to [...] Read more.
Colorectal cancer is one of the three most common cancers worldwide. Polyps are complex and have unclear boundaries, often leading to inaccurate boundary segmentation and missed detections. To address these challenges, we propose a boundary constraint multi-level feature aggregation framework called BMFA-Net to precisely segment polyps. The framework comprises four key modules. First, the parallel partial decoder is introduced to aggregate high-level features within the network to generate a globally informative semantic map serving as the initial guidance region for reverse erasing the foreground. Second, we propose an efficient atrous convolution attention module to effectively aggregate local and global contextual information over multiple levels. Additionally, a multi-level feature aggregation mechanism is designed and placed among the efficient atrous convolution attention modules to enable the network to capture a large amount of semantic structure while preserving intricate details. Finally, a boundary constraint reverse attention module is proposed to perform the boundary constraint while removing the foreground to improve the quality of boundary segmentation. Extensive experiments demonstrated the superiority and versatility of our framework compared with state-of-the-art methods; specifically, it achieved a mean Dice score of 0.922 on the CVC-300 dataset. Full article
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11 pages, 2621 KiB  
Article
Effects of Long-Term Rice–Crayfish Coculture Systems on Soil Nutrients, Carbon Pools, and Rice Yields in Northern Zhejiang Province, China
by Baojun Wang, Hongmei Zhang, Gui Chen, Wangda Cheng and Yaqiang Shen
Agronomy 2024, 14(5), 1014; https://doi.org/10.3390/agronomy14051014 (registering DOI) - 10 May 2024
Abstract
This research was to examine the impacts of long-term integrated rice–crayfish farming on soil nutrients, carbon pools, and rice yields in paddy fields. The aim was to establish a scientific basis for the sustainable development of RS in the northern region of Zhejiang. [...] Read more.
This research was to examine the impacts of long-term integrated rice–crayfish farming on soil nutrients, carbon pools, and rice yields in paddy fields. The aim was to establish a scientific basis for the sustainable development of RS in the northern region of Zhejiang. The results showed that the change from rice monoculture (CK) to rice–crayfish coculture systems (RS) led to a 24.99% increase in the 5-year average of soil ammonium nitrogen (AN), while the soil nitrate nitrogen (NN), available potassium (AK), and available phosphorus content (AP) decreased by 28.02%, 16.05%, and 28.76%, respectively. Moreover, the total organic carbon (TOC), easily oxidizable organic carbon (EOC), dissolved organic carbon (DOC), and microbial biomass carbon (MBC) exhibited a reduction of 2.45%, 8.82%, 35.31%, and 65.84%, respectively. Correlation analysis revealed a significant positive correlation between NN, EOC, and MBC in the RS mode. In terms of rice yield, the 5-year average of rice yield in RS decreased by 8.40% compared to CK. The mean yield of early-maturing rice varieties was reduced by 13.16%, while that of late-maturing rice varieties was reduced by 6.00%. These results shed light on the annual variation in soil nutrients, carbon pools, and rice yield in the RS mode, providing insights for the sustainable development of RS in northern Zhejiang. Full article
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19 pages, 477 KiB  
Review
Immunology of Physical Exercise: Is Equus caballus an Appropriate Animal Model for Human Athletes?
by Olga Witkowska-Piłaszewicz, Katarzyna Malin, Izabela Dąbrowska, Jowita Grzędzicka, Piotr Ostaszewski and Craig Carter
Int. J. Mol. Sci. 2024, 25(10), 5210; https://doi.org/10.3390/ijms25105210 (registering DOI) - 10 May 2024
Abstract
Domestic horses routinely participate in vigorous and various athletic activities. This enables the horse to serve as a model for studying athletic physiology and immunology in other species, including humans. For instance, as a model of physical efforts, such as endurance rides (long-distance [...] Read more.
Domestic horses routinely participate in vigorous and various athletic activities. This enables the horse to serve as a model for studying athletic physiology and immunology in other species, including humans. For instance, as a model of physical efforts, such as endurance rides (long-distance running/aerobic exercise) and races (anaerobic exercise), the horse can be useful in evaluating post-exercise response. Currently, there has been significant interest in finding biomarkers, which characterize the advancement of training and adaptation to physical exercise in the horse. The parallels in cellular responses to physical exercises, such as changes in receptor expression and blood cell activity, improve our understanding of the mechanisms involved in the body’s response to intense physical activity. This study focuses on the changes in levels of the pro- and anti-inflammatory cytokines and cellular response in the context of post-exercise immune response. Both the direction of changes in cytokine levels and cellular responses of the body, such as proliferation and expression of surface markers on lymphocytes, monocytes and neutrophils, show cross-functional similarities. This review reveals that horses are robust research models for studying the immune response to physical exercise in human athletes. Full article
22 pages, 5916 KiB  
Article
Analyzing Sustainable 3D Printing Processes: Mechanical, Thermal, and Crystallographic Insights
by Alexandra-Ileana Portoacă, Alin Diniță, Maria Tănase, Alexandru Săvulescu, Elena-Emilia Sirbu, Catălina Călin and Gheorghe Brănoiu
Polymers 2024, 16(10), 1364; https://doi.org/10.3390/polym16101364 (registering DOI) - 10 May 2024
Abstract
In this study, the objective was to optimize energy consumption in the fused deposition modeling (FDM) 3D printing process via a detailed analysis of printing parameters. By utilizing thermal analysis techniques, this research aimed to identify lower printing temperatures that could lead to [...] Read more.
In this study, the objective was to optimize energy consumption in the fused deposition modeling (FDM) 3D printing process via a detailed analysis of printing parameters. By utilizing thermal analysis techniques, this research aimed to identify lower printing temperatures that could lead to reduced energy usage. Experimental analysis was conducted using a three-level L9 Taguchi orthogonal array, which involved a systematic combination of different extruder temperatures and cooling fan capacities. Furthermore, the research incorporated differential scanning calorimetry (DSC) and X-ray diffraction (XRD) methods to analyze the thermal properties and crystallinity of the 3D-printed specimens. The results indicated that temperature was a key factor affecting crystallinity, with samples printed at 190 °C and 60% fan capacity showing the highest mean values. By conducting a multi-objective desirability analysis, the optimal conditions for maximizing ultimate tensile strength (UTS), tensile modulus, and elongation at break while minimizing energy consumption for PLA 3D-printed samples were determined to be a temperature of 180 °C and a fan speed of 80%. Full article
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23 pages, 909 KiB  
Article
Preparation and Adsorption Performance of Boron Adsorbents Derived from Modified Waste Feathers
by Dongxing Li, Hui Jiang, Zhengwei Luo, Wenhua Geng and Jianliang Zhu
Polymers 2024, 16(10), 1365; https://doi.org/10.3390/polym16101365 (registering DOI) - 10 May 2024
Abstract
This research focuses on modifying discarded feathers by grafting glycidyl methacrylate (GMA) onto their surface through thiolation, followed by an epoxy ring-opening reaction with N-methyl-D-glucamine (NMDG) to synthesize feather-based boron adsorbents. Optimization of the adsorbent preparation conditions was achieved through single-factor experiments, varying [...] Read more.
This research focuses on modifying discarded feathers by grafting glycidyl methacrylate (GMA) onto their surface through thiolation, followed by an epoxy ring-opening reaction with N-methyl-D-glucamine (NMDG) to synthesize feather-based boron adsorbents. Optimization of the adsorbent preparation conditions was achieved through single-factor experiments, varying temperature, time, GMA concentration, and initiator dosage. The synthesized adsorbent (F-g-GMA-NMDG) underwent characterization using Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and X-ray diffraction (XRD). The adsorption behavior of the adsorbent was studied, and its boron adsorption capacity at different temperatures was determined through static adsorption kinetic curves. Analysis of adsorption isotherms, kinetics, and thermodynamics was conducted. Results indicate that the boron adsorption process by F-g-GMA-NMDG follows a pseudo-second-order model. The adsorption process is endothermic, with higher temperatures promoting adsorption efficiency. Gibbs free energy (ΔG) confirms the spontaneity of the adsorption process. Enhanced adsorption efficacy was observed under neutral and acidic pH conditions. After four cycles, the adsorbent maintained its adsorption efficiency, demonstrating its stability and potential for reuse. This study provides novel insights into both the treatment of discarded feathers and the development of boron adsorbents. Full article
(This article belongs to the Section Circular and Green Polymer Science)
16 pages, 1667 KiB  
Article
Mitogenome Assembly Reveals Gene Migration and RNA Editing Events in Plateau Hongliu (Myricaria elegans Royle.)
by Xue Li, Hao Wu, Xingyao Hu, Yunhua Wu, Feng Nie, Tao Su, Mei Han and Fuliang Cao
Forests 2024, 15(5), 835; https://doi.org/10.3390/f15050835 (registering DOI) - 10 May 2024
Abstract
The Plateau Hongliu (Myricaria elegans Royle.) is a woody shrub halophyte that thrives in arid areas of western Tibet, in the Himalayan Mountains. It is acclaimed as superior in saline stress acclimation and as a critical pharmaceutical resource of the Tibetan traditional [...] Read more.
The Plateau Hongliu (Myricaria elegans Royle.) is a woody shrub halophyte that thrives in arid areas of western Tibet, in the Himalayan Mountains. It is acclaimed as superior in saline stress acclimation and as a critical pharmaceutical resource of the Tibetan traditional herb. Nevertheless, the mitogenome in the genus Myricaria remains unknown. Here, using the Illumina and PacBio sequencing assays, the first complete mitogenome of the M. elegans revealed a multi-branched skeleton with a total length of 416,354 bp and GC content of 44.33%, comprising two circular molecules (M1 and 2). The complete mitogenome annotates 31 unique protein-encoding genes (PEGs), fifteen tRNAs, and three rRNA genes. The UAA exhibits the most prominent codon usage preference as a termination, followed by UUA codons for leucine. The mitogenome contains 99 simple sequence repeats and 353 pairs of dispersed repeats, displaying the most frequent in palindromic repeats. Gene transfer analyses identified 8438 bp of 18 homologous fragments from the plastome, accounting for 2.03% of the total length. Using the PREP suite, 350 C-U RNA editing sites were predicted, of which nad4 and ccmB were on the top frequency. Syntenic and phylogenetic analyses suggested weakly conserved patterns of M. elegans in Caryophyllales owing to the genome rearrangement. In summary, the deciphered unique features and complexities of the mitogenome in M. elegans provide novel insights into understanding the evolution and biological conservation underlying climate resilience in halophytes. Full article
(This article belongs to the Section Forest Ecophysiology and Biology)
15 pages, 1499 KiB  
Article
Applying Hydrochar Affects Soil Carbon Dynamics by Altering the Characteristics of Soil Aggregates and Microbes
by Ting Yan, Zherui Zhang, Zhe Zhang, Wenzan Wang, Dong Li, Tao Zhang and Zhiping Zhu
Agronomy 2024, 14(5), 1015; https://doi.org/10.3390/agronomy14051015 (registering DOI) - 10 May 2024
Abstract
Hydrochar as a carbon-based fertiliser is hypothesised to permanently improve soils by modifying soil carbon quality through the regulation of soil organic carbon dynamics, aggregation properties and microbial diversity. However, the interactions between soil organic carbon (SOC) molecular structure, soil aggregates and soil [...] Read more.
Hydrochar as a carbon-based fertiliser is hypothesised to permanently improve soils by modifying soil carbon quality through the regulation of soil organic carbon dynamics, aggregation properties and microbial diversity. However, the interactions between soil organic carbon (SOC) molecular structure, soil aggregates and soil microbial communities as a result of hydrochar application have not been fully elucidated. In this study, the use of hydrochar derived from duck farm biomass waste for a maize cultivation experiment verified that hydrochar had a promoting effect on maize growth, effectively increasing the nutrient supply to the soil. The application of hydrochar increased the soil organic carbon content by 78 to 253 per cent, which was dominated by CHON-type lignin, carbohydrates and condensed aromatic structural compounds. Meanwhile, hydrochar had a significant effect on both soil aromatic structures and oxygenated functional groups, forming more soil macroaggregates. In addition, hydrochar had a positive effect on soil bacterial abundance. This study suggests that the key mechanism by which hydrochar regulates soil carbon dynamics is mainly through the stabilising effect of hydrochar on macroaggregates while increasing the abundance of carbon-related microscopic bacteria. These results will help to elucidate the potential effects of aqueous carbon on the biogeochemical cycling of carbon in soils. Full article
(This article belongs to the Section Agricultural Biosystem and Biological Engineering)

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