In this article, we contend that understanding Brazil’s current communicative landscape requires a closer examination of the relevance of legacy media outlets, challenging the widely accepted “traditional media bypass” thesis, which posits that social media platforms have overtaken traditional media as the primary influencers of political discourse, an argument often used to explain the rise of extreme-right ideologies across different national contexts. In order to test the association between voting preferences and the use of different types of media, we employ logistic regression analysis using data from a recent survey that includes numerous questions about the information and media consumption habits of Brazilian voters. Our findings highlight that legacy media, particularly broadcast TV channels like Globo, Record, and SBT, remain dominant in Brazil as sources of political information. Contrary to the bypass thesis, Bolsonaro’s supporters, while favoring social media, also consume significant amounts of legacy media. Analysis reveals stark differences in media preferences between the supporters of different political candidates, challenging the notion of an exclusive reliance on social media by right-wing supporters. The data also indicate nuanced media consumption habits, such as a preference for certain TV channels and fact-checking behaviors, underscoring the complex interplay between legacy and social media. Full article

Bilayer electrospun fibers aimed to be used for skin tissue engineering applications were fabricated for enhanced cell attachment and proliferation. Different ratios of PHBV-PLLA (70:30, 80:20, and 90:10 w/w) blends were electrospun on previously formed electrospun PHBV membranes to produce their bilayers. The fabricated electrospun membranes were characterized with FTIR, which conformed to the characteristic peaks assigned for both PHBV and PLLA. The surface morphology was evaluated using SEM analysis that showed random fibers with porous morphology. The fiber diameter and pore size were measured in the range of 0.7 ± 0.1 µm and 1.9 ± 0.2 µm, respectively. The tensile properties of the bilayers were determined using an electrodynamic testing system. Bilayers had higher elongation at break (44.45%) compared to the monolayers (28.41%) and improved ultimate tensile strength (7.940 MPa) compared to the PHBV monolayer (2.450 MPa). In vitro cytotoxicity of each of the scaffolds was determined via culturing MC3T3 (pre-osteoblastic cell line) on the membranes. Proliferation was evaluated using the Alamar Blue assay on days 3, 7, and 14, respectively. SEM images of cells cultured on membranes were taken in addition to bright field imaging to visually show cell attachment. Fluorescent nuclear staining performed with DAPI was imaged with an inverted fluorescent microscope. The fabricated bilayer shows high mechanical strength as well as biocompatibility with good cell proliferation and cell attachment, showing potential for skin substitute applications. Full article

The highly virulent Toxoplasma gondii RH strain is maintained through successive passages in mice, but there is still a lack of studies that refine these procedures from a 3Rs perspective, where humanitarian ideals aim to minimize the stress, pain, or suffering of the animals used in the research without the loss of results. The aim of this study was to establish humane endpoints in Swiss Webster mice inoculated with the T. gondii RH strain. A total of 52 mice were infected with 5 × 10⁶ tachyzoites/mL and monitored for periods of up to 5 days. The parameters body weight; hair condition; higher than normal body temperature; hypothermia; respiratory function; pain; soft stools or diarrhea; bloody diarrhea; tense, nervous, or in distress during handling; and ascites were recorded daily in score tables. The results showed that prominent piloerection, respiratory function, pain parameters, and ascites are important clinical signs to be used as a cut-off point for implementing euthanasia. The application of this refinement method helped to avoid animal suffering and pain without compromising the number of parasites recovered. We therefore suggest adopting these parameters in research protocols that require the maintenance of the T. gondii RH strain in murine models to avoid and reduce animal suffering. Full article

This historiographical study examines the Russian Orthodox Mission in Beijing from 1715 to 1956, revealing its historical impact on Christianity in China and Sino–Russian cultural exchanges. The research explores how the Mission functioned not only as a religious entity but also influenced diplomatic ties and scholarly pursuits, as documented in both Chinese and Russian historiographies. This study utilizes contemporary sources, exploring Chinese narratives to re-evaluate historical perspectives, and portrays the Mission as a critical mediator in Sino–Russian relations. An examination of the historical context shows that the Mission has undergone a transformation over time. It has evolved from an influential ecclesiastical presence to a cultural and diplomatic agency unobtrusively entered into Chinese society. From the mid-18th to the early 20th century, the Mission adapted to the local environment by combining the transmission of religious doctrine with engagement in China’s political and cultural contexts. The article proposes a holistic interpretation of the Mission’s function, encompassing not only evangelism but also diplomatic engagements, and adding to the multifaceted discourse within Chinese cultural heritage. In summary, the article recommends exploring the enduring impact and historical complexities of the Russian Orthodox Mission as it is grounded in a broader framework of global movements. The research suggests that it may be beneficial to broaden the scope of historiographic narratives to encompass a diverse range of interdisciplinary studies that reflect the complexity of the Mission’s enduring impact and its role in shaping a shared global history. Full article

Shostakovich’s direct quotation from the Odessan street song “Bagels, Buy My Bagels!” (Bubliki, kupite bubliki!) in his Second Cello Concerto Op. 126 (1966) featured an unusual style, even in relation to some of his other compositions referencing popular and Jewish music. The song is widely known as one of the icons of the Odessa underworld. Shostakovich’s use of this melody as one of the main leit-themes of the Concerto can be compared to the use by the non-Jewish Andrei Sinyavsky of the Jewish pseudonym Abram Tertz, a bandit from the Odessa underworld—the only locus of freedom to tell the truth in a totalitarian society. The time of Shostakovich’s address to this song remarkably coincided with the famous Soviet trial of Andrei Sinyavsky and Yuly Daniel in the fall of 1965 and their final sentencing (February 1966) to years in a Gulag camp. The dramaturgy of Shostakovich’s Concerto, written in the same spring of 1966, demonstrates the transformation of the theme of “Bagels” into a tragic image. The totality of circumstantial evidence suggests that this opus could be the composer’s hidden tribute to the feats of Russian heroic writers. Full article

How have funding, art education, and politics affected the development of performance and interdisciplinary art? In England in particular, performance as an experimental and radical art practice developed largely from underground activities, political action and a range of art forms. Funding bodies, colleges and art institutions eventually accommodated, albeit to a limited extent, this activity. As financial circumstances were sometimes difficult, artists often provided their own support structures and organisations. Some of these became established as they became successful. Performance art split from the theatrical and became defined as live art. In more recent times, conditions shifted again, and critical, experimental, or avant-garde theatre, film, music, etc., found refuge within contemporary art. Performance however, became increasingly confined and restricted by: the regulatory and academic requirements within universities; the need for evidence for some form of public or social purpose by funding bodies; and the increasingly hostile social and political circumstances. This research draws partly from personal experience and reflects on cultural conditions since the 1970s. Full article

This study addresses the issue of poor construction labor productivity, exploring the process and methodology for increasing construction workers’ participation in labor productivity improvement, as well as a situational awareness (SA) development approach for construction workers based on lean construction (LC). A framework for enhancing labor productivity through SA has been developed. A case study approach is utilized to describe the LC improvement process, which includes enhancing construction workers’ SA for waste minimization and process optimization and engaging them in LC with improved value stream mapping (VSM). The labor productivity measurement approach, combined with VSM, is used to evaluate the labor productivity improvement with labor productivity improvement rate, resource efficiency, and flow efficiency. The results demonstrate that the labor productivity of the case project has increased by 24.07%, with 11.54% contributing resource efficiency and 88.46% contributing flow efficiency, indicating a greater increase in flow efficiency. This study fills a research gap in terms of the combination of construction workers’ SA enhancement and the involvement of LC practices to boost labor productivity. Furthermore, this study proposes an SA development approach based on LC at three levels: waste perception, VSM implementation, and labor productivity improvement assessment. This provides new perspectives for leveraging construction workers’ SA to increase labor productivity. The improved VSM approach and labor productivity measurements provide an operationalization of workers’ participation in continuous improvement. This research is of great practical relevance for augmenting the competencies of construction laborers and inspiring them to engage in labor productivity enhancement. Full article

In order to maximize the utilization efficiency of renewable energy resources and reduce carbon costs in multi-park integrated energy systems (MIESs), this paper proposes an electricity–carbon energy scheduling method for MIESs, where a electricity–carbon joint trading market is established to allow energy interactions between IESs so as to satisfy their energy deficiencies and surpluses. Simultaneously, through leveraging differences in carbon prices among regions, carbon quotas are shared between all IESs, thereby reducing the overall carbon trading costs within the region. The paper also suggests that to encourage carbon cooperation between IESs, incentive measures such as government subsidies could be provided to foster collaboration. The simulation results demonstrate that the proposed electricity–carbon energy scheduling method for MIESs can effectively improve the utilization flexibility of various energy resources and obtain the higher economic benefits, compared with the traditional method where each IES operates independently. Full article

(1) Introduction: Despite documented clinical and pain discrepancies between male and female osteoarthritis (OA) patients, the underlying mechanisms remain unclear. Synovial myofibroblasts, implicated in synovial fibrosis and OA-related pain, offer a potential explanation for these sex differences. Additionally, interleukin-24 (IL24), known for its role in autoimmune disorders and potential myofibroblast production, adds complexity to understanding sex-specific variations in OA. We investigate its role in OA and its contribution to observed sex differences. (2) Methods: To assess gender-specific variations, we analyzed myofibroblast marker expression and IL24 levels in synovial tissue samples from propensity-matched male and female OA patients (each n = 34). Gene expression was quantified using quantitative polymerase chain reaction (qPCR). The association between IL24 expression levels and pain severity, measured by a visual analog scale (VAS), was examined to understand the link between IL24 and OA pain. Synovial fibroblast subsets, including CD45-CD31-CD39- (fibroblast) and CD45-CD31-CD39+ (myofibroblast), were magnetically isolated from female patients (n = 5), and IL24 expression was compared between these subsets. (3) Results: Females exhibited significantly higher expression of myofibroblast markers (MYH11, ET1, ENTPD2) and IL24 compared to males. IL24 expression positively correlated with pain severity in females, while no correlation was observed in males. Further exploration revealed that the myofibroblast fraction highly expressed IL24 compared to the fibroblast fraction in both male and female samples. There was no difference in the myofibroblast fraction between males and females. (4) Conclusions: Our study highlights the gender-specific role of myofibroblasts and IL24 in OA pathogenesis. Elevated IL24 levels in females, correlating with pain severity, suggest its involvement in OA pain experiences. The potential therapeutic implications of IL24, demonstrated in autoimmune disorders, open avenues for targeted interventions. Notwithstanding the limitations of the study, our findings contribute to understanding OA’s multifaceted nature and advocate for future research exploring mechanistic underpinnings and clinical applications of IL24 in synovial myofibroblasts. Additionally, future research directions should focus on elucidating the precise mechanisms by which IL24 contributes to OA pathology and exploring its potential as a therapeutic target for personalized medicine approaches. Full article

We introduce an innovative deep learning approach specifically designed for the environment identification of intelligent vehicles under rainy conditions in this paper. In the construction of wireless vehicular communication networks, an innovative approach is proposed that incorporates additional multipath components to simulate the impact of raindrop scattering on the vehicle-to-vehicle (V2V) channel, thereby emulating the channel characteristics of vehicular environments under rainy conditions and an equalization strategy in OFDM-based systems is proposed at the receiver end to counteract channel distortion. Then, a rainy environment identification method for autonomous vehicles is proposed. The core of this method lies in utilizing the Channel State Information (CSI) shared within the vehicular network to accurately identify the diverse rainy environments in which the vehicle operates without relying on traditional sensors. The environmental identification task is considered as a multi-class classification problem and a dedicated Convolutional Neural Network (CNN) model is proposed. This CNN model uses the CSI estimated from CAM exchanged in vehicle-to-vehicle (V2V) communication as training features. Simulation results showed that our method achieved an accuracy rate of 95.7% in recognizing various rainy environments, which significantly surpasses existing classical classification models. Moreover, it only took microseconds to predict with high accuracy, surpassing the performance limitations of traditional sensing systems under adverse weather conditions. This breakthrough ensures that intelligent vehicles can rapidly and accurately adjust driving parameters even in complex weather conditions like rain to autonomous drive safely and reliably. Full article

Due to widespread overuse, pharmaceutical compounds, such as antibiotics, are becoming increasingly prevalent in greater concentrations in aquatic ecosystems. In this study, we investigated the capacity of the white-rot fungus, Coriolopsis gallica (a high-laccase-producing fungus), to biodegrade ampicillin under different cultivation conditions. The biodegradation of the antibiotic was confirmed using high-performance liquid chromatography, and its antibacterial activity was evaluated using the bacterial growth inhibition agar well diffusion method, with Escherichia coli as an ampicillin-sensitive test strain. C. gallica successfully eliminated ampicillin (50 mg L⁻¹) after 6 days of incubation in a liquid medium. The best results were achieved with a 9-day-old fungal culture, which treated a high concentration (500 mg L⁻¹) of ampicillin within 3 days. This higher antibiotic removal rate was concomitant with the maximum laccase production in the culture supernatant. Meanwhile, four consecutive doses of 500 mg L⁻¹ of ampicillin were removed by the same fungal culture within 24 days. After that, the fungus failed to remove the antibiotic. The measurement of the ligninolytic enzyme activity showed that C. gallica laccase might participate in the bioremediation of ampicillin. Full article

Conventional quality control methodologies are inadequate for fully elucidating the aberrant patterns of product quality. A multitude of factors influence product quality, yet the limited number of controlled quality characteristics is insufficient for accurately diagnosing quality abnormalities. Additionally, there are asymmetries in data collection, data pre-processing, and model interpretation. In this context, a quality anomaly recognition and diagnosis model for the complex product manufacturing process is constructed based on a deep residual network, support vector machine (SVM), and Shapley additive explanation (SHAP). Given the numerous complex product quality characteristic indexes and unpredictable accidental factors in the production process, it is necessary to mine the deep relationship between quality characteristic data and quality state. This mining is achieved by utilizing the strong feature extraction ability of the deep residual shrinkage network (DRSN) through self-learning. The symmetry of the data within the model has also been taken into account to ensure a more balanced and comprehensive analysis. The excellent binary classification ability of the support vector machine is combined with the DRSN to identify the quality anomaly state. The SHAP interpretable model is employed to diagnose the quality anomaly problem of a single product and to identify and diagnose quality anomalies in the manufacturing process of complex products. The effectiveness of the model is validated through case analysis. The accuracy of the DRSN-SVM quality anomaly recognition model reaches 99%, as demonstrated by example analysis, and the model exhibits faster convergence and significantly higher accuracy compared with the naive Bayesian model classification and support vector machine classification models. Full article

This is the first report of parasitic granulomatous dermatitis caused by Pelodera spp. in a buffalo. The affected buffalo was about seven years old, was a female of the Murrah breed and belonged to a property located on Marajó Island in the State of Pará. During the clinical examination, the animal was in a standing position and presented several multifocal nodular and placoid masses throughout the body, mostly on the forelimbs, hindlimbs, abdomen, mammary glands, perineum, vulva and tail. These masses were also observed on the nasal mucosa, head, neck, back and chest. On macroscopic examination, the skin had several multifocal-to-coalescent sessile nodular and placoid lesions. Histopathology of the skin showed a marked reduction in the number of hair follicles. In the superficial dermis, there was significant multifocal-to-coalescent inflammatory infiltration, consisting of macrophages, epithelioid macrophages, lymphocytes, plasma cells and multinucleated giant cells. In the remaining hair follicles, there were numerous cross and longitudinal sections of small rhabditoid nematodes characterized by a thin cuticle, platymyarian musculature, an intestinal tract, a rhabditiform esophagus and lateral alae (morphologically compatible with Pelodera spp.). The diagnosis of parasitic dermatitis was confirmed by histopathological skin lesions associated with the presence of intralesional rhabditiform larvae morphologically compatible with Pelodera spp. Full article

The recovery of Au(III) from solution using adsorbents in the form of granules or powders is challenging due to issues such as instability during the recovery process or mass loss caused by small particle size. This study introduces a PEI-TCT/PVDF composite membrane designed to intercept and capture Au(III) in wastewater. Experimental results demonstrated that the PEI-TCT/PVDF membrane exhibits a broad pH range (1–8) and a high retention efficiency for Au(III) of 97.8%, with a maximum adsorption capacity of 294.5 mg/g. The mechanism of Au(III) adsorption on the PEI-TCT/PVDF membrane was mainly through electrostatic adsorption, which caused AuCl₄⁻ to aggregate on the surface of the membrane and gradually reduced to Au⁰ and Au⁺. Furthermore, the membrane can be entirely regenerated within 20 min and maintains its performance in subsequent adsorption cycles. This study highlights the potential of PEI-TCT/PVDF membranes for the recovery of precious Au(III). Full article

We designed a narrow-linewidth external-cavity hybrid laser leveraging a silicon-on-insulator triple Euler gradient resonant ring. The laser’s outer cavity incorporates a compact, high-Q resonant ring with low loss. The straight waveguide part of the resonant ring adopts a width of 1.6 μm to ensure low loss transmission. The curved section is designed as an Euler gradient curved waveguide, which is beneficial for low loss and stable single-mode transmission. The design features an effective bending radius of only 26.35 μm, which significantly improves the compactness of the resonant ring and, in turn, reduces the overall footprint of the outer cavity chip. To bolster the laser power and cater to the varying shapes of semiconductor optical amplifier (SOA) spots, we designed a multi-tip edge coupler. Theoretical analysis indicates that this edge coupler can achieve an optical coupling efficiency of 85%. It also reveals that the edge coupler provides 3 dB vertical and horizontal alignment tolerances of 0.76 μm and 2.4 μm, respectively, for a spot with a beam waist radius of 1.98 μm × 0.99 μm. The outer cavity, designed with an Euler gradient micro-ring, can achieve a side-mode suppression ratio (SMSR) of 30 dB within a tuning range of 100 nm, with a round-trip loss of the entire cavity at 1.12 dB, and an expected theoretical laser linewidth of 300 Hz. Full article

This study was conducted to identify the physical and psychological difficulties of children with atopic dermatitis and their caregivers, and to investigate the effects of participation in a novel therapeutic gardening program based on psychological intervention on their physical and mental health. The program, consisting of 15 sessions, was conducted for approximately 4 months in urban gardens in Seoul and involved 30 children with atopic dermatitis and their caregivers. Additionally, a control group of 30 non-participating caregivers was recruited for comparative analysis. The psychological and emotional changes in caregivers were assessed using six self-report scales (depression, anxiety, stress, vitality, life satisfaction, parenting efficacy) before and after participation in the program. Additionally, the depression index (CDI) and atopic dermatitis index (SCORAD, TEWL) were measured for the children with atopic dermatitis. The research results indicate that the therapeutic gardening program utilizing psychological intervention had a positive impact on the physiological and psychological health of participants. These results are significant as they demonstrate the clinical application of the professionally developed therapeutic gardening program through active intervention and operation. This study suggests that this program can serve as an effective intervention in improving the mental health of both children with atopic dermatitis and their caregivers. Full article

Soil cadmium (Cd) contamination poses a serious threat to ecosystems, and the application of phosphorus fertilizers can reduce Cd toxicity. However, the specific effects of different phosphorus fertilizers on the subcellular distribution and chemical morphology of Cd in eggplant grown in calcareous Cd-contaminated soil remain unclear. This study examined the impact of various types and levels of phosphate fertilizers on the subcellular distribution and chemical morphology of cadmium in eggplant seedlings using a two-factor analysis. The investigation was conducted via a pot experiment utilizing a two-factor analysis. The application of 0.35 g kg⁻¹ dicalcium phosphate significantly decreased the Cd content in the subcellular distribution and induced notable alterations in the chemical morphology of Cd in eggplant roots. Specifically, the ethanol-extracted Cd state decreased by 65.45%, and the sodium chloride-extracted Cd state decreased by 64.65%. Conversely, Cd extracted by deionized water, acetic acid, hydrochloric acid, and the residue state increased by 6.20%, 4.01%, 20.87%, and 17.85%, respectively. The application of 0.35 g kg⁻¹ dicalcium phosphate resulted in the most significant reduction in Cd content in eggplant and modification of subcellular Cd distribution and chemical morphology in roots. Full article

The brain is complex and metabolically active, and the detection of metabolites plays an important role in brain development and diseases. Currently, there is a lack of research on the metabolic spectrum changes in learning and memory impairment, and hippocampal damage induced by microwave radiation from the metabolic perspective. Aiming to provide sensitive indicators for microwave radiation-induced brain damage and establish a foundation for understanding its injury mechanisms, this study employed non-targeted metabolomics to investigate metabolic fluctuations and key metabolic pathway alterations in rats’ hippocampal tissue after microwave radiation. The memory and spatial exploration abilities of rats decreased after radiation. The postsynaptic densities were thickened in the MW group. The cholesterol sulfate, SM(d16:1/24:1(15Z)), and linoelaidylcarnitine were significantly increased after radiation, whereas etrahydrocorticosterone, L-phenylalanine, and histamine were significantly decreased after radiation. These metabolites were enriched in signaling pathways related to the inflammatory mediator regulation of transient receptor potential (TRP) channels, neuroactive ligand–receptor interaction, steroid hormone biosynthesis, and phenylalanine, tyrosine, and tryptophan biosynthesis. These findings indicate that microwave radiation causes spatial learning and memory dysfunction in rats and structural damage to hippocampal tissue. Full article

Antihypertensive agents are commonly prescribed to manage hypertension and are known to be beneficial for bone formation and remodeling. The aim of this systematic review was to assess the impact that antihypertensive agents have on dental implant stability, osseointegration, and survival outcomes. A review of the literature was conducted using articles from 11 data sources. PRISMA guidelines were followed, and a PICO question was constructed. The search string “Antihypertensive* AND dental implant* AND (osseointegration OR stability OR survival OR success OR failure)” was used for all data sources where possible. The Critical Appraisal Skills Programme (CASP) was used for study appraisal, including the risk of bias. The search resulted in 7726 articles. After selection according to eligibility criteria, seven articles were obtained (one randomized control trial, two prospective cohort studies, three retrospective cohort studies, and a case control study). Five papers investigated the effects of antihypertensive agents on primary stability, but there were discrepancies in the method of assessment. Inhibition of the renin–angiotensin–aldosterone system was linked to higher primary stability. Secondary stability was usually higher than primary stability, but it is unknown if antihypertensive agents caused this. Survival outcomes were increased with certain antihypertensive agents. It is possible that inhibition of the renin–angiotensin–aldosterone system may lead to greater bone mineral density, improved primary stability, and improved survival outcomes although the effects on osseointegration are unknown. However, more research is needed to confirm this theory. Full article

Australian governments continue to search for a model capable of planning future urban settlements at an extended spatial scale (the mega-metropolitan region) to accommodate high population growth more sustainably. Attempts at decentralisation over the past half century have failed, as state capital cities continue to sprawl in an unsustainable manner and increase their primacy at the expense of regional cities. This paper examines how two technologies, broadband and fast rail—both infrastructures capable of re-shaping space–time relationships—could underpin a transition of Australia’s largest capital cities into megacity regions by functionally integrating regional cities into their core metropolitan agglomerations. With the Melbourne megacity region as a spatial framework, changes in population and economic development are examined for Melbourne and several regional cities in Victoria following the introduction of regional fast rail (RFR) and broadband. The impact of high-speed rail (HSR) for intercity corridors in southeast England is analysed as a possible analogue for future application in Victoria. The results revealed that RFR primarily served to extend capital city suburban development. Only HSR had the capacity to ‘punch through’ and boost growth for ‘basic’ new economy industries in ‘on-line’ urban centres in corridors linked to London. High-speed broadband proved most attractive to Melbourne’s agglomeration of high-skilled information workers. Lower speed broadband services were more uniformly taken up across all centres. This discussion speculates on the impacts of these and other green economy and digitalisation drivers on prospects for a future megacity region transition in Victoria. Full article

Background and Objectives: Chronic radiotherapy-induced skin injury (cRISI) is an irreversible and progressive condition that can significantly impact a patient’s quality of life. Despite the limited literature available on the assessment of the epidermal barrier in cRISI, there is a consensus that appropriate skincare, including the use of emollients, is the primary therapeutic approach for this group of patients. The aim of this study was to evaluate the biophysical properties of the skin during the late period (at least 90 days) following radiation therapy (RT) for head and neck cancer. Materials and Methods: This was a single-center prospective non-randomized study. It involved the analysis of 16 adult patients with head and neck cancer who underwent RT at the Greater Poland Cancer Center, along with 15 healthy volunteers. The study and control groups were matched for gender and age (p = 0.51). Clinical assessment, based on the LENT-SOMA scale, was conducted for all patients. Evaluation of the skin’s biophysical properties included: an analysis of transepidermal water loss (TEWL), stratum corneum hydration (SCH), and skin visualization using high-frequency ultrasonography (HF-USG). Results: A significantly higher TEWL was observed in the irradiated area compared to the control area in the study group (p = 0.004). However, there was no statistically significant difference in SCH (p = 0.073). Additionally, no significant difference was observed in the values of TEWL and SCH in the irradiated area between the group of patients with and without clinically obvious RISI (p = 0.192 and p = 0.415, respectively). The skin thickness of the irradiated area, assessed by HF-USG, did not differ significantly from the skin thickness of the control area (p = 0.638). Furthermore, no difference in skin thickness was observed in patients with clinical features of cRISI in the irradiated and control areas (p = 0.345). The mean time after RT was 6.1 years. Conclusions: This study marks the first demonstration of epidermal barrier damage in patients in the long term following RT for head and neck cancer. The impairment of the epidermal barrier was observed independently of evident cRISI features. This observation underscores the necessity to recommend appropriate skin care, including the use of emollients, for all patients following RT. We also suggest that HF-USG examination is generally inconclusive in determining the degree of skin damage in the late period after RT. Full article

The urban–rural fringe is at the forefront of the confrontation between the agricultural and industrial civilisations. How to handle the relationship between the two civilisations in this region and ensure its sustainable development is an eternal topic in the science of the human-living environment. Thanks to the special historical background of the Third Line construction, China’s industrial heritage connects with the urban–rural fringe that surpasses other countries. For the first time, this study connects China’s Third Line construction, industrial heritage, and urban–rural integration within the same context, combining big data bibliometric methods to obtain the development characteristics and context of China’s industrial heritage research starting from 2004. It has strong policy characteristics, is influenced by administrative orders, and is aligned with urbanisation efforts. Theoretical exploration is the first step in research, followed by value connotations and cultural qualities. It addresses various topics, including industrial heritage conservation, regeneration approaches, and cultural heritage tourism. The research focuses primarily on the value appraisal of industrial heritage, exploring revitalisation tactics and routes, as well as regional development models in urban–rural periphery areas. This study also examines how scholars generally consider the impact of industrial heritage on the economic, social, and cultural development of urban–rural fringe areas in order to integrate and propose various protection and utilisation strategies, such as industrial heritage preservation, cultural and creative industry development, and tourism resource development. Full article