The 2023 MDPI Annual Report has
been released!
 
18 pages, 369 KiB  
Article
Consumption of Meats and Fish in Poland during the COVID-19 Lockdown Period
by Dominika Szajnoga, Helena Perenc, Grzegorz K. Jakubiak, Grzegorz Cieślar and Małgorzata Ćwieląg-Drabek
Nutrients 2024, 16(9), 1318; https://doi.org/10.3390/nu16091318 (registering DOI) - 27 Apr 2024
Abstract
The COVID-19 pandemic and related restrictions have significantly impacted the quality of life of society in many countries in various aspects. The purpose of this study was to examine how the COVID-19 pandemic affected the consumption of meat and fish in society in [...] Read more.
The COVID-19 pandemic and related restrictions have significantly impacted the quality of life of society in many countries in various aspects. The purpose of this study was to examine how the COVID-19 pandemic affected the consumption of meat and fish in society in Poland as well as the factors that determined these changes. The cross-sectional study was conducted using an original online questionnaire between 8th and 18th of April 2020. The subjects were selected randomly. The target population were adults living in Poland. The inclusion criterion for the study was the age of at least 18 years and consent to selfless participation in the study. Communication via social media such as Facebook or Instagram was used to enroll more participants from different socio-demographic subgroups. The questionnaire was divided into two parts—the first part contained questions about sex, age, body mass, body height, residence, level of education, and occupation, and the second part consisted of specific questions about the consumption frequency of different kinds of meat during the COVID-19 lockdown period (in comparison to the time before the pandemic). A total of 3888 people took part in the study including 84.54% women, with an average age of 30.17 ± 9.22 years. The frequency of poultry consumption increased, while for pork, beef, ham and other meat products as well as fish and seafood it declined. The factors that influenced the change in dietary patterns during the lockdown related to the COVID-19 pandemic included age, body mass index, gender, place of residence, and type of work performed. However, no relationship was found between the change in meat and fish consumption during the pandemic and the level of education and form of employment during the pandemic. Full article
(This article belongs to the Special Issue Eating Habits and Nutritional Aspects during the COVID-19 Pandemic)
19 pages, 6625 KiB  
Article
Spatiotemporal Evolution of Ecological Environment Quality and Driving Factors in Jiaodong Peninsula, China
by Wenhui Guo and Ranghui Wang
Sustainability 2024, 16(9), 3676; https://doi.org/10.3390/su16093676 (registering DOI) - 27 Apr 2024
Abstract
To monitor the Ecological Environment Quality (EEQ) of the Jiaodong Peninsula and provide a scientific basis for ecological environment governance and sustainable development in the region, this study evaluates the EEQ of Jiaodong using the Remote Sensing-based Ecological Index (RSEI) model and analyzes [...] Read more.
To monitor the Ecological Environment Quality (EEQ) of the Jiaodong Peninsula and provide a scientific basis for ecological environment governance and sustainable development in the region, this study evaluates the EEQ of Jiaodong using the Remote Sensing-based Ecological Index (RSEI) model and analyzes its spatiotemporal evolution patterns, building upon single-factor correlation analysis using the Random Sample Consensus (RANSAC) algorithm, using GeoDetector to analyze the driving mechanisms of human activities and natural factors in EEQ. The results indicate the following: (1) The average RSEI values for 2000, 2010, and 2020 are 0.60, 0.57, and 0.66, with Good or Excellent areas accounting for 56.48%, 51.02%, and 67.17%. From 2000 to 2020, RSEI strong improvement areas were predominantly distributed in the eastern hilly areas of the Jiaodong Peninsula. The RSEI of the Jiaodong Peninsula showed significant spatial autocorrelation. (2) The RANSAC algorithm effectively reduces noise interference in remote sensing data, thereby improving the accuracy of single-factor correlation analysis. (3) In 2000, the importance of natural factors exceeds that of human activity factors. The Standardized Precipitation Evapotranspiration Index (SPEI) is the most important driving factor; while in 2010 and 2020, human activity factors surpass natural factors in importance, with the Land Use Composite Index (LUCI) being the most significant driving factor. The driving factors exhibited double-factor and nonlinear enhancement. The most significant interaction factors affecting the EEQ of the Jiaodong Peninsula in 2000, 2010, and 2020 are SPEI∩GDP, LUCI∩SPEI, and LUCI∩GDP. Full article
(This article belongs to the Section Environmental Sustainability and Applications)
12 pages, 918 KiB  
Article
Advanced Detection of Failed LEDs in a Short Circuit for Automotive Lighting Applications
by Jose R. Martínez-Pérez, Miguel A. Carvajal, Juan J. Santaella, Nuria López-Ruiz, Pablo Escobedo and Antonio Martínez-Olmos
Sensors 2024, 24(9), 2802; https://doi.org/10.3390/s24092802 (registering DOI) - 27 Apr 2024
Abstract
This paper addresses the issue of LED short-circuit fault detection in signaling and lighting systems in the automotive industry. The conventional diagnostic method commonly implemented in newer vehicles relies on measuring the voltage drop across different LED branches and comparing it with threshold [...] Read more.
This paper addresses the issue of LED short-circuit fault detection in signaling and lighting systems in the automotive industry. The conventional diagnostic method commonly implemented in newer vehicles relies on measuring the voltage drop across different LED branches and comparing it with threshold values indicating faults caused by open circuits or LED short circuits. With this algorithm, detecting cases of a few LEDs short-circuited within a branch, particularly a single malfunctioning LED, is particularly challenging. In this work, two easily implementable algorithms are proposed to address this issue within the vehicle’s control unit. One is based on a mathematical prediction model, while the other utilizes a neural network. The results obtained offer a 100% LED short-circuit fault detection rate in the majority of analyzed cases, representing a significant improvement over the conventional method, even in scenarios involving a single malfunctioning LED within a branch. Additionally, the neural network-based model can accurately predict the number of failed LEDs. Full article
(This article belongs to the Section Industrial Sensors)
19 pages, 4751 KiB  
Article
Effect of Baffle Board on Aerodynamic and Stealth Performance of Double S-Duct Caret Intake
by Bin Wang, Qiang Wang and Sichen Li
Appl. Sci. 2024, 14(9), 3747; https://doi.org/10.3390/app14093747 (registering DOI) - 27 Apr 2024
Abstract
Intake is not only the main air supply component of an aircraft, but also one of the forward radar scattering sources. The aerodynamic and stealth performance of intake is critical to the serviceability of advanced fighter aircrafts. The effects of baffle boards with [...] Read more.
Intake is not only the main air supply component of an aircraft, but also one of the forward radar scattering sources. The aerodynamic and stealth performance of intake is critical to the serviceability of advanced fighter aircrafts. The effects of baffle boards with different configurations on the performance of the caret intake with a double S-duct diffuser are presented in this article. The multi-level fast multipole method (MLFMM) and the SST k-ω turbulence model were respectively used to calculate the surface current and the flow field. It was found that the average RCS value of intake can be effectively reduced by installing the baffle board with vertical orientation in the front diffuser, with the DC60 value and the loss of outlet total pressure both increased slightly. The boundary layer separation and the RCS characteristics of intake were closely related to the configuration of the corrugated baffle board. Compared with the traditional curved board, by installing the corrugated board with optimized corrugation number and shape, the stealth performance of intake can be further improved, and the loss of aerodynamic performance can be also reduced. Full article
(This article belongs to the Section Aerospace Science and Engineering)
15 pages, 2504 KiB  
Article
Analysis of the Influence Mechanism of Nanomaterials on Spontaneous Imbibition of Chang 7 Tight Reservoir Core
by Xiaoxiang Wang, Yang Zhang, Xinmeng Wu, Xin Fan, Desheng Zhou and Jinze Xu
Processes 2024, 12(5), 890; https://doi.org/10.3390/pr12050890 (registering DOI) - 27 Apr 2024
Abstract
This study investigates the impact of nanomaterials on different surfactant solutions. By measuring the parameters (including emulsification property, zeta potential, DLS, CA, IFT, etc.) of imbibition liquid system with nanoparticles and without nanoparticles, combining with imbibition experiments, the law and mechanism of improving [...] Read more.
This study investigates the impact of nanomaterials on different surfactant solutions. By measuring the parameters (including emulsification property, zeta potential, DLS, CA, IFT, etc.) of imbibition liquid system with nanoparticles and without nanoparticles, combining with imbibition experiments, the law and mechanism of improving the imbibition recovery of nanomaterials were obtained. The findings demonstrate that the nano-silica sol enhances the emulsification and dispersion of crude oil in the surfactant system, resulting in smaller and more uniform particle sizes for emulsified oil droplets. Non-ionic surfactant AEO-7 has the best effect under the synergistic action of nanomaterials. Zeta potential and DLS tests also showed that AEO-7 exhibits smaller particle sizes due to their insignificant electrostatic interaction with nanoparticles. Furthermore, the addition of nanomaterials enhances the hydrophilicity of core and reduces the interfacial tension. Under the synergistic action of nanoparticles, AEO-7 still showed the best enhanced core hydrophilicity (CA 0.61° after imbibition) and the lowest interfacial tension (0.1750 mN·m−1). In the imbibition experiment, the imbibition recovery of the system with nanomaterials is higher than that of the non-nanomaterials. The mixed system of AEO-7 and nano-silica sol ZZ-1 has the highest imbibition recovery (49.27%). Combined with the experiments above, it shows that nanomaterials have a good effect on enhancing the recovery rate of tight core, and the synergistic effect of non-ionic surfactant AEO-7 with nanomaterials is the best. Moreover, nanomaterials reduce adhesion work within the system while improving spontaneous imbibition recovery. These findings provide theoretical guidance for better understanding the mechanism behind nanomaterial-induced imbibition enhancement as well as improving tight oil’s imbibition recovery. Full article
(This article belongs to the Section Energy Systems)
13 pages, 1625 KiB  
Article
An Isotonic Drink Containing Pacific Cod (Gadus macrocephalus) Processing Waste Collagen Hydrolysate for Bone and Cartilage Health
by Nikita Yu. Zarubin, Elena N. Kharenko, Olga V. Bredikhina, Elizaveta V. Lavrukhina, Kira S. Rysakova, Vitaly Yu. Novikov, Georgy E. Leonov, Igor V. Vakhrushev, Konstantin V. Zolotarev, Anton N. Mikhailov and Marina V. Mikhailova
Mar. Drugs 2024, 22(5), 202; https://doi.org/10.3390/md22050202 (registering DOI) - 27 Apr 2024
Abstract
Malnutrition is one of the major factors of bone and cartilage disorders. Pacific cod (Gadus macrocephalus) processing waste is a cheap and highly promising source of bioactive substances, including collagen-derived peptides and amino acids, for bone and cartilage structure stabilization. The [...] Read more.
Malnutrition is one of the major factors of bone and cartilage disorders. Pacific cod (Gadus macrocephalus) processing waste is a cheap and highly promising source of bioactive substances, including collagen-derived peptides and amino acids, for bone and cartilage structure stabilization. The addition of these substances to a functional drink is one of the ways to achieve their fast intestinal absorption. Collagen hydrolysate was obtained via enzymatic hydrolysis, ultrafiltration, freeze-drying, and grinding to powder. The lyophilized hydrolysate was a light gray powder with high protein content (>90%), including collagen (about 85% of total protein) and a complete set of essential and non-essential amino acids. The hydrolysate had no observed adverse effect on human mesenchymal stem cell morphology, viability, or proliferation. The hydrolysate was applicable as a protein food supply or a structure-forming food component due to the presence of collagen fiber fragments. An isotonic fitness drink (osmolality 298.1 ± 2.1 mOsm/L) containing hydrolysate and vitamin C as a cofactor in collagen biosynthesis was prepared. The addition of the hydrolysate did not adversely affect its organoleptic parameters. The production of such functional foods and drinks is one of the beneficial ways of fish processing waste utilization. Full article
(This article belongs to the Special Issue Bioactive Compounds from Marine Fish)
7 pages, 303 KiB  
Case Report
Autoimmune Encephalitis following Checkpoint Inhibitor Therapy in a Patient with Metastatic Melanoma in Complete Remission
by Giuseppe Civardi, Alessia Medioli, Carlotta Braghieri, Massimo Ambroggi, Paolo Immovilli, Simone Orsucci, Paolo Contini, Giuseppe Aronica and Luigi Cavanna
Medicina 2024, 60(5), 728; https://doi.org/10.3390/medicina60050728 (registering DOI) - 27 Apr 2024
Abstract
The use of immune checkpoint inhibitors (ICIs) in cancer is increasing. Their side effects are mainly due to the triggering of autoimmunity, which are mild or moderate and include skin rash, colitis, hepatitis, endocrine disorders, myositis, interstitial lung disorder, etc., in most cases [...] Read more.
The use of immune checkpoint inhibitors (ICIs) in cancer is increasing. Their side effects are mainly due to the triggering of autoimmunity, which are mild or moderate and include skin rash, colitis, hepatitis, endocrine disorders, myositis, interstitial lung disorder, etc., in most cases during the course of therapy. Autoimmune encephalitis (AE) is rare in cancer patients treated with ICIs. Fifty patients with ICI-related encephalitis were identified in a recent review. Herein, we report a case of pembrolizumab associated with AE with a favorable short-term prognosis. A 68-year-old man with malignant metastatic melanoma achieved complete remission after pembrolizumab treatment. However, 10 months after pembrolizumab cessation due to grade 3 diarrhea, he developed confusion, an altered mental status, progressive memory loss, and gait disturbance. He was admitted to the neurologic department, and a comprehensive neurological workup, brain magnetic resonance imaging, cerebral fluid analysis, EEG, and blood test allowed the diagnosis of autoimmune encephalitis. The patient was treated with plasmapheresis, a high dose of intravenous steroids, and intravenous immunoglobulins. The patient improved, and he is now well with a performance status of 1. This case is interesting since the AE developed approximately 10 months after the cessation of immunotherapy, the underlying cancer was in complete remission, and the AE showed a good response after the treatment was performed. Full article
(This article belongs to the Section Oncology)
21 pages, 3359 KiB  
Article
The Relevance of Surface Resistances on the Conductive Thermal Resistance of Lightweight Steel-Framed Walls: A Numerical Simulation Study
by Paulo Santos, David Abrantes, Paulo Lopes and Ligia Moga
Appl. Sci. 2024, 14(9), 3748; https://doi.org/10.3390/app14093748 (registering DOI) - 27 Apr 2024
Abstract
The accurate evaluation of the thermal performance of building envelope components (e.g., facade walls) is crucial for the reliable evaluation of their energy efficiency. There are several methods available to quantify their thermal resistance, such as analytical formulations (e.g., ISO 6946 simplified calculation [...] Read more.
The accurate evaluation of the thermal performance of building envelope components (e.g., facade walls) is crucial for the reliable evaluation of their energy efficiency. There are several methods available to quantify their thermal resistance, such as analytical formulations (e.g., ISO 6946 simplified calculation method), numerical simulations (e.g., using finite element method), experimental measurements under lab-controlled conditions or in situ. Regarding measurements, when using the heat flow meter (HFM) method, very often, the measured value is based on surface conditions (e.g., temperature and heat flux), achieving in this way the so-called surface-to-surface or conductive thermal resistance (). When the building components are made of homogeneous layers, their values are constant, regardless of their internal and external surface boundary conditions. However, whenever this element is composed of inhomogeneous layers, such as in lightweight steel-framed (LSF) walls, their values are no longer constant, depending on their thermal surface resistance. In the literature, such systematic research into how these values vary is not available. In this study, the values of four LSF walls were computed, with different levels of thermal conductivity inhomogeneity, making use of four finite elements’ numerical simulation tools. Six external thermal surface resistances () were modelled, ranging from 0.00 up to 0.20 m2·K/W. The average temperature of the partition LSF walls is 15 °C, while for the facade LSF walls it is 10 °C. It was found that the accuracy values of all evaluated numerical software are very high and similar, the values being nearly constant for walls with homogeneous layers, as expected. However, the variation in the value depends on the level of inhomogeneity in the LSF wall layers, increasing up to 8%, i.e., +0.123 m2·K/W, for the evaluated values. Full article
20 pages, 942 KiB  
Article
Motivations toward Electronic Word-of-Mouth Sending Behavior Regarding Restaurant Experiences in the Millennial Generation
by Giovanny Haro-Sosa, Beatriz Moliner-Velázquez, Irene Gil-Saura and Maria Fuentes-Blasco
J. Theor. Appl. Electron. Commer. Res. 2024, 19(2), 993-1012; https://doi.org/10.3390/jtaer19020052 (registering DOI) - 27 Apr 2024
Abstract
A growing body of the literature on the study of online reviews presents interesting research opportunities, especially in services highly frequented by young consumer segments, such as restaurants. In this context, the present study examines the restaurant electronic word-of-mouth (EWOM) behavior of Millennial [...] Read more.
A growing body of the literature on the study of online reviews presents interesting research opportunities, especially in services highly frequented by young consumer segments, such as restaurants. In this context, the present study examines the restaurant electronic word-of-mouth (EWOM) behavior of Millennial consumers by addressing both review queries before the purchase decision and writing and sending after the purchase. Based on the theory of reasoned action, a double objective is pursued. On the one hand, the influence of motivations related to extroversion, social benefits, and altruism on EWOM sending behavior is analyzed. On the other hand, the moderating role of EWOM consultation in these relationships is studied. Using a sample of 341 Millennials from Ecuador, a structural model is constructed that confirms the contribution of two types of motivations in sending EWOM: those of extroversion and those of social benefits. The results also reveal the moderating role of EWOM consultation alone in the effects of extraversion and altruism motivations. Managerial implications for restaurants derived from this study include improvements in the design of digital communication strategies tailored to Millennial customers based on their motivations. Full article
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13 pages, 283 KiB  
Review
Prognosis and Treatment of Gastric Cancer: A 2024 Update
by Claudia Burz, Vlad Pop, Ciprian Silaghi, Iulia Lupan and Gabriel Samasca
Cancers 2024, 16(9), 1708; https://doi.org/10.3390/cancers16091708 (registering DOI) - 27 Apr 2024
Abstract
Due to the high death rate associated with gastric cancer, a great deal of research has been conducted on this disease. The goal of this paper was to start a trimestral review of 2024 for the year that had just started. The scientific [...] Read more.
Due to the high death rate associated with gastric cancer, a great deal of research has been conducted on this disease. The goal of this paper was to start a trimestral review of 2024 for the year that had just started. The scientific literature from 1 January 2024 was chosen with consideration of the the guidelines of the European Society of Medical Oncology (ESMO), which are updated with new findings but not systematically reviewed annually. We used the search term “gastric cancer” to find the most current publications in the PubMed database related to the prognosis and treatment of gastric cancer. As previously said, the only articles that satisfied the inclusion criteria were those from 2024. Articles with case reports were eliminated since they had nothing to do with our research. The treatment of gastric cancer is the focus of the majority of articles from 2024. The primary research axes include surgery and immunonutrition, immunotherapy and Helicobacter pylori, and therapeutic targets. Patients with GC may experience less psychological, social, and financial hardship if the recently identified markers discovered in circulation are better assessed and validated. This could be achieved by either including the markers in an artificial intelligence-based diagnostic score or by using them in conjunction with traditional diagnostic methods. Due to the rising death rate associated with GC, funding for research into diagnosis, prognosis, therapy, and therapeutic targets is essential. Full article
(This article belongs to the Special Issue Advances in the Prognosis of Gastrointestinal Cancers)
15 pages, 351 KiB  
Article
Depth-Optimized Quantum Circuits for ASCON: AEAD and HASH
by Yujin Oh, Kyungbae Jang, Anubhab Baksi and Hwajeong Seo
Mathematics 2024, 12(9), 1337; https://doi.org/10.3390/math12091337 (registering DOI) - 27 Apr 2024
Abstract
Quantum computing advancements pose security challenges for cryptography. Specifically, Grover’s search algorithm affects the reduction in the search complexity of symmetric-key encryption and hash functions. Recent efforts have been made to estimate the complexity of Grover’s search and evaluate post-quantum security. In this [...] Read more.
Quantum computing advancements pose security challenges for cryptography. Specifically, Grover’s search algorithm affects the reduction in the search complexity of symmetric-key encryption and hash functions. Recent efforts have been made to estimate the complexity of Grover’s search and evaluate post-quantum security. In this paper, we propose a depth-optimized quantum circuit implementation for ASCON, including both symmetric-key encryption and hashing algorithms, as a part of the lightweight cryptography standardization by NIST (National Institute of Standards and Technology). As far as we know, this is the first implementation of a quantum circuit for the ASCON AEAD (Authenticated Encryption with Associated Data) scheme, which is a symmetric-key algorithm. Also, our quantum circuit implementation of the ASCON-HASH achieves a reduction of more than 88.9% in the Toffoli depth and more than 80.5% in the full depth compared to the previous work. As per our understanding, the most effective strategy against Grover’s search involves minimizing the depth of the quantum circuit for the target cipher. We showcase the optimal Grover’s search cost for ASCON and introduce a proposed quantum circuit optimized for depth. Furthermore, we utilize the estimated cost to evaluate post-quantum security strength of ASCON, employing the relevant evaluation criteria and the latest advancements in research. Full article
(This article belongs to the Special Issue Quantum Cryptography and Applications)
17 pages, 9001 KiB  
Article
Investigation of the Penetration Performance of the Radial Forging Process for Wrought Aluminium Alloy
by Yongfei Wang, Linhua Xiong, Dongxiao Feng, Shengdun Zhao and Yi Guo
Materials 2024, 17(9), 2065; https://doi.org/10.3390/ma17092065 (registering DOI) - 27 Apr 2024
Abstract
With the wide application potential of wrought aluminium alloy in aerospace, automobile and electronic products, high-quality aluminium bars prepared by the radial forging (RF) process have received extensive attention. Penetration performance refers to the depth of radial plastic deformation of forgings, which is [...] Read more.
With the wide application potential of wrought aluminium alloy in aerospace, automobile and electronic products, high-quality aluminium bars prepared by the radial forging (RF) process have received extensive attention. Penetration performance refers to the depth of radial plastic deformation of forgings, which is the key factor in determining the quality of forging. In this work, the penetration performance of the radial forging process for 6063 wrought aluminium bars is investigated by simulation using FORGE software. The minimum reduction amount of the hammer is calculated based on the forging penetration theory of forging. The influence of process parameters including forging ratio (FR) and billet temperature on the effective stress and hammer load in the RF process are investigated. The RF-deformed billet is then produced with the optimal process parameters obtained from the simulation results. The average grain size of aluminium alloy semi-solid spherical material is used to evaluate the forging penetration. Simulation results showed that the effective strain at the edge and the centre of the RF-deformed billet gradually increases, but the increasing speed of the effective strain at the edge becomes low. The hammer load first decreases quickly and then gradually maintains stability by increasing the FR. It is found that low billet temperature and high FR should be selected as appropriate process parameters under the allowable tonnage range of RF equipment. Under an isothermal temperature of 630 °C and a sustaining time of 10 min, the difference in the average grain dimension between the edge and the centre positions of the starting extruded blank is 186.43 μm, while the difference in the average grain dimension between the edge and the centre positions of the RF-deformed blank is 15.09 μm. The improvement ratio of penetration performance for the RF-deformed blank is obtained as 91.19%. Full article
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24 pages, 631 KiB  
Article
How Professional and Market Logics and the Conflict between Institutional Demands Affect Hospital Accreditation Compliance: A Multiple-Case Study in Brazil
by Tiago Martins Ramos da Silva ⊃⊃ and Luciano Rossoni
Healthcare 2024, 12(9), 914; https://doi.org/10.3390/healthcare12090914 (registering DOI) - 27 Apr 2024
Abstract
Hospital accreditation has become ubiquitous in developing countries. While research acknowledges that accreditation can enhance healthcare quality, efficiency, and safety, concerns persist regarding hospitals’ management of conflicts stemming from the diverse institutional logic inherent in this process. Therefore, this study aimed to investigate [...] Read more.
Hospital accreditation has become ubiquitous in developing countries. While research acknowledges that accreditation can enhance healthcare quality, efficiency, and safety, concerns persist regarding hospitals’ management of conflicts stemming from the diverse institutional logic inherent in this process. Therefore, this study aimed to investigate how professional and market logic, alongside conflicts arising from institutional demands, affect compliance with hospital accreditation. To this end, we conducted a multiple-case study in four Brazilian hospitals employing in-depth interviews and on-site observations. The triangulation of narrative analysis and the outcomes of multiple correspondence analysis revealed that when professional logic predominates, there is a greater propensity to tailor accredited activities by segmenting the tasks between physicians and nurses with the intention of mitigating existing conflicts. Conversely, when conflicts occur over established goals between professionals and orientated marked logic executives, the accreditation process is impeded, resulting in non-compliance. Ultimately, the findings underscore the alignment between the pursuit of legitimacy and efficiency within the accreditation process. We conclude by delineating the theoretical and practical implications of scrutinizing the internal dynamics of institutional logic. Full article
(This article belongs to the Section Healthcare Quality and Patient Safety)
17 pages, 420 KiB  
Article
Nitrogen-Rich Sewage Sludge Mineralized Quickly, Improving Lettuce Nutrition and Yield, with Reduced Risk of Heavy Metal Contamination of Soil and Plant Tissues
by Margarida Arrobas, Ramily Meneses, Andressa Gribler Gusmão, Julieta Moreira da Silva, Carlos Manuel Correia and Manuel Ângelo Rodrigues
Agronomy 2024, 14(5), 924; https://doi.org/10.3390/agronomy14050924 (registering DOI) - 27 Apr 2024
Abstract
Sewage sludge should primarily find use in agriculture, reducing the quantity directed towards alternative disposal methods like incineration or deposition in municipal landfills. This study evaluated the agronomic value and the risk of soil and plant tissue contamination with heavy metals in sewage [...] Read more.
Sewage sludge should primarily find use in agriculture, reducing the quantity directed towards alternative disposal methods like incineration or deposition in municipal landfills. This study evaluated the agronomic value and the risk of soil and plant tissue contamination with heavy metals in sewage sludge obtained from two wastewater treatment plants (WWTP). The experiment was arranged as a 2 × 5 factorial (two sewage sludges, five sanitation treatments), involving lettuce cultivation in pots over two growing cycles. The two sewage sludges were sourced from the WWTPs of Gelfa and Viana do Castelo and underwent five sanitation and stabilization treatments (40% and 20% calcium oxide, 40% and 20% calcium hydroxide, and untreated sewage sludge). The Gelfa sewage sludge, characterized by a higher initial nitrogen (N) concentration, resulted in greater dry-matter yield (DMY) (12.4 and 8.6 g plant−1 for the first and second growing cycles, respectively) compared to that from Viana do Castelo (11.0 and 8.1 g plant−1), with N release likely being a major factor influencing crop productivity. The high N concentration and the low carbon (C)/N ratio of sewage sludge led to rapid mineralization of the organic substrate, which additionally led to a higher release of other important nutrients, such as phosphorus (P) and boron (B), making them available for plant uptake. Alkalizing treatments further stimulated sewage sludge mineralization, increasing soil pH and exchangeable calcium (Ca), thereby enhancing Ca availability for plants, and indicating a preference for use in acidic soils. Cationic micronutrients were minimally affected by the sewage sludge and their treatments. The concentrations of heavy metals in the sewage sludge, soils, and lettuce tissues were all below internationally established threshold limits. This study highlighted the high fertilizing value of these sewage sludges, supplying N, P, and B to plants, while demonstrating a low risk of environmental contamination with heavy metals. Nevertheless, the safe use of sewage sludge by farmers depends on monitoring other risks, such as toxic organic compounds, which were not evaluated in this study. Full article
11 pages, 344 KiB  
Brief Report
Examining the Effect of Genes on Depression as Mediated by Smoking and Modified by Sex
by Kirsten Voorhies, Julian Hecker, Sanghun Lee, Georg Hahn, Dmitry Prokopenko, Merry-Lynn McDonald, Alexander C. Wu, Ann Wu, John E. Hokanson, Michael H. Cho, Christoph Lange, Karin F. Hoth and Sharon M. Lutz
Genes 2024, 15(5), 565; https://doi.org/10.3390/genes15050565 (registering DOI) - 27 Apr 2024
Abstract
Depression is heritable, differs by sex, and has environmental risk factors such as cigarette smoking. However, the effect of single nucleotide polymorphisms (SNPs) on depression through cigarette smoking and the role of sex is unclear. In order to examine the association of SNPs [...] Read more.
Depression is heritable, differs by sex, and has environmental risk factors such as cigarette smoking. However, the effect of single nucleotide polymorphisms (SNPs) on depression through cigarette smoking and the role of sex is unclear. In order to examine the association of SNPs with depression and smoking in the UK Biobank with replication in the COPDGene study, we used counterfactual-based mediation analysis to test the indirect or mediated effect of SNPs on broad depression through the log of pack-years of cigarette smoking, adjusting for age, sex, current smoking status, and genetic ancestry (via principal components). In secondary analyses, we adjusted for age, sex, current smoking status, genetic ancestry (via principal components), income, education, and living status (urban vs. rural). In addition, we examined sex-stratified mediation models and sex-moderated mediation models. For both analyses, we adjusted for age, current smoking status, and genetic ancestry (via principal components). In the UK Biobank, rs6424532 [LOC105378800] had a statistically significant indirect effect on broad depression through the log of pack-years of cigarette smoking (p = 4.0 × 10−4) among all participants and a marginally significant indirect effect among females (p = 0.02) and males (p = 4.0 × 10−3). Moreover, rs10501696 [GRM5] had a marginally significant indirect effect on broad depression through the log of pack-years of cigarette smoking (p = 0.01) among all participants and a significant indirect effect among females (p = 2.2 × 10−3). In the secondary analyses, the sex-moderated indirect effect was marginally significant for rs10501696 [GRM5] on broad depression through the log of pack-years of cigarette smoking (p = 0.01). In the COPDGene study, the effect of an SNP (rs10501696) in GRM5 on depressive symptoms and medication was mediated by log of pack-years (p = 0.02); however, no SNPs had a sex-moderated mediated effect on depressive symptoms. In the UK Biobank, we found SNPs in two genes [LOC105378800, GRM5] with an indirect effect on broad depression through the log of pack-years of cigarette smoking. In addition, the indirect effect for GRM5 on broad depression through smoking may be moderated by sex. These results suggest that genetic regions associated with broad depression may be mediated by cigarette smoking and this relationship may be moderated by sex. Full article
(This article belongs to the Section Molecular Genetics and Genomics)
13 pages, 637 KiB  
Article
Unique Specific Jumping Test for Measuring Explosive Power in Young Basketball Players: Differences by Gender, Age, and Playing Positions
by Asaf Shalom, Roni Gottlieb, Pedro E. Alcaraz and Julio Calleja-Gonzalez
Sports 2024, 12(5), 118; https://doi.org/10.3390/sports12050118 (registering DOI) - 27 Apr 2024
Abstract
When playing basketball, players are required to have high explosive power, which requires the ability to move in efficient, specific, and game-specific movement patterns that combine both horizontal and vertical abilities. Differences have been seen between young male and female basketball players in [...] Read more.
When playing basketball, players are required to have high explosive power, which requires the ability to move in efficient, specific, and game-specific movement patterns that combine both horizontal and vertical abilities. Differences have been seen between young male and female basketball players in this measure. The aim of this study was to examine differences in players’ unique movements by gender, age, and playing positions using a novel test for basketball players. This study included 232 young basketball players, male and female, from a range of Israeli leagues, who were divided into three categories: under-14, under-16, and under-18. Our findings showed that males presented better results than females in all age categories. Moreover, females in the under-18 category presented better results than those in the under-14 category, but not more than those in the under-16 category. Differences in playing positions were only examined between males and females in the under-18 category, where players begin to specialize in playing positions, and here, guards showed better results than forwards and centers. Our conclusions highlight the importance of including unique, sport-specific tests in talent identification and selection processes, as these tests can provide valuable information about a player’s skill set and potential for success. The findings are presented in an achievement table of the expected physical fitness results by age and gender for the benefit of basketball coaches and strength and conditioning coaches when assessing their players. Full article
17 pages, 4983 KiB  
Article
Potential Involvement of the South American Lungfish Intelectin-2 in Innate-Associated Immune Modulation
by Gabriela Patrícia Martins de Almeida Bernardes, Gustavo Marques Serra, Lucas da Silva e Silva, Maíra Pompeu Martins, Louise Neiva Perez, Fábio Alberto de Molfetta, Agenor Valadares Santos and Maria Paula Cruz Schneider
Int. J. Mol. Sci. 2024, 25(9), 4798; https://doi.org/10.3390/ijms25094798 (registering DOI) - 27 Apr 2024
Abstract
Intelectins belong to a family of lectins with specific and transitory carbohydrate interaction capabilities. These interactions are related to the activity of agglutinating pathogens, as intelectins play a significant role in immunity. Despite the prominent immune defense function of intelectins, limited information about [...] Read more.
Intelectins belong to a family of lectins with specific and transitory carbohydrate interaction capabilities. These interactions are related to the activity of agglutinating pathogens, as intelectins play a significant role in immunity. Despite the prominent immune defense function of intelectins, limited information about its structural characteristics and carbohydrate interaction properties is available. This study investigated an intelectin transcript identified in RNA-seq data obtained from the South American lungfish (Lepidosiren paradoxa), namely LpITLN2-B. The structural analyses predicted LpITLN2-B to be a homo-trimeric globular protein with the fibrinogen-like functional domain (FReD), exhibiting a molecular mass of 57 kDa. The quaternary structure is subdivided into three monomers, A, B, and C, and each domain comprises 11 β-sheets: an anti-parallel β-sheet, a β-hairpin, and a disordered β-sheet structure. Molecular docking demonstrates a significant interaction with disaccharides rather than monosaccharides. The preferential interaction with disaccharides highlights the potential interaction with pathogen molecules, such as LPS and Poly(I:C). The hemagglutination assay inhibited lectins activity, especially maltose and sucrose, highlighting lectin activity in L. paradoxa samples. Overall, our results show the potential relevance of LpITLN2-B in L. paradoxa immune defense against pathogens. Full article
(This article belongs to the Special Issue Fish Immunology 4.0)
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23 pages, 7133 KiB  
Article
Experimental Testing on Tuned Liquid Dampers for Implementation in Industrial Chimneys
by Giancarlo Marulli and Carlos Moutinho
Sensors 2024, 24(9), 2800; https://doi.org/10.3390/s24092800 (registering DOI) - 27 Apr 2024
Abstract
A TLD is a passive damping device that works by dissipating energy through the sloshing of the liquid and the effect of wave breaking, thereby controlling the vibrations of the structure. One of the applications where TLDs are of great interest is in [...] Read more.
A TLD is a passive damping device that works by dissipating energy through the sloshing of the liquid and the effect of wave breaking, thereby controlling the vibrations of the structure. One of the applications where TLDs are of great interest is in the case of industrial chimneys since these structures often have a very low natural frequency, which can be easily achieved in a control device of this type. The main objective of this study is to evaluate the behaviour of an annular TLD composed of multiple cells through laboratory tests and investigate if it is adequate to design it as an agglomeration of smaller rectangular TLDs. The influence of the amplitude of displacement on the behaviour of the annular TLD will also be analysed. The tests were performed on a shaking table and recurring with pendulums of the same length but of different masses. Three reservoirs were studied as TLDs: a rectangular one, a cell of an annular TLD and a quarter-ring of an annular TLD. This study concluded that the analytical methods developed in previous studies were, in general, adequate for the design of a rectangular TLD and that it was reasonable to design the annular TLD studied as a combination of rectangular ones, as its cells were a close match to a rectangle of similar dimensions. It was also concluded that a compartmentalised annular TLD is an adequate solution for the vibration control of structures with high displacements. Full article
(This article belongs to the Special Issue Novel Sensors for Structural Health Monitoring)
16 pages, 778 KiB  
Article
Bilateral Elimination Rule-Based Finite Class Bayesian Inference System for Circular and Linear Walking Prediction
by Wentao Sheng, Tianyu Gao, Keyao Liang and Yumo Wang
Biomimetics 2024, 9(5), 266; https://doi.org/10.3390/biomimetics9050266 (registering DOI) - 27 Apr 2024
Abstract
Objective: The prediction of upcoming circular walking during linear walking is important for the usability and safety of the interaction between a lower limb assistive device and the wearer. This study aims to build a bilateral elimination rule-based finite class Bayesian inference system [...] Read more.
Objective: The prediction of upcoming circular walking during linear walking is important for the usability and safety of the interaction between a lower limb assistive device and the wearer. This study aims to build a bilateral elimination rule-based finite class Bayesian inference system (BER-FC-BesIS) with the ability to predict the transition between circular walking and linear walking using inertial measurement units. Methods: Bilateral motion data of the human body were used to improve the recognition and prediction accuracy of BER-FC-BesIS. Results: The mean predicted time of BER-FC-BesIS in predicting the left and right lower limbs’ upcoming steady walking activities is 119.32 ± 9.71 ms and 113.75 ± 11.83 ms, respectively. The mean time differences between the predicted time and the real time of BER-FC-BesIS in the left and right lower limbs’ prediction are 14.22 ± 3.74 ms and 13.59 ± 4.92 ms, respectively. The prediction accuracy of BER-FC-BesIS is 93.98%. Conclusion: Upcoming steady walking activities (e.g., linear walking and circular walking) can be accurately predicted by BER-FC-BesIS innovatively. Significance: This study could be helpful and instructional to improve the lower limb assistive devices’ capabilities of walking activity prediction with emphasis on non-linear walking activities in daily living. Full article
(This article belongs to the Special Issue Biomimetic Aspects of Human–Computer Interactions)
14 pages, 900 KiB  
Article
The Impact of Utilizing Waste Sunflower Oil as a Biodiesel Blend on Four-Stroke Engine Performance and Emissions
by Qais Hussein Hassan, Alaa Salahuddin Araibi, A. H. Shather, Malik M. Mohammed and Hayder A. Alalwan
Designs 2024, 8(3), 38; https://doi.org/10.3390/designs8030038 (registering DOI) - 27 Apr 2024
Abstract
The blending of biodiesel with petroleum diesel attracts much attention due to its high potential in reducing emissions. In this work, waste sunflower oil was converted to biodiesel by the trans-esterification method, and it was blended with petroleum diesel in three ratios (10, [...] Read more.
The blending of biodiesel with petroleum diesel attracts much attention due to its high potential in reducing emissions. In this work, waste sunflower oil was converted to biodiesel by the trans-esterification method, and it was blended with petroleum diesel in three ratios (10, 30, and 50%). The impact of using these blended fuels in a four-stroke engine on engine performance and exhaust emissions at three engine loads (2, 4, and 6 N.m.) was investigated and compared with the use of petroleum diesel and biodiesel. The engine performance was evaluated by determining the brake-specific fuel consumption (BSFC), engine effective power (Ne), brake-specific energy consumption (BSEC), brake thermal efficiency (BTE), and noise intensity. The evaluation of emissions from the engine exhaust was carried out by measuring the levels of carbon oxides (CO and CO2), hydrocarbons (HC), nitrogen oxides (NO and NO2), and particulate matter (PM). The results show that blending diesel with up to 30% biodiesel can reduce CO, HC, and PM emissions by 29.6 ± 1%, 26.0 ± 4%, and 31.0 ± 3%, respectively. However, this decrease is associated with increasing CO2 and NOx emissions by 18.5 ± 2.5% and 29.0 ± 6%, respectively. In addition, the engine showed acceptable performance when using up to 30% biodiesel, where the increase in fuel consumption was limited to 5.8 ± 0.3%. In addition, the engine’s effective power increased with the blending ratio of 10% by 2.0 ± 0.6%, but then decreased with the blending ratio of 30% by only 2.0 ± 0.6%. The noise intensity was also decreased by 2.4%, while BSEC and BTE were reduced by only 2.9 ± 0.9% and 3.5 ± 1%, respectively. The results of this work provide deep insights regarding the utilization of waste sunflower oil as biodiesel to be blended with petroleum diesel, which is a considerable novel approach in the energy and environmental sectors. Full article
(This article belongs to the Section Vehicle Engineering Design)
18 pages, 2293 KiB  
Article
An Automated Fish-Feeding System Based on CNN and GRU Neural Networks
by Surak Son and Yina Jeong
Sustainability 2024, 16(9), 3675; https://doi.org/10.3390/su16093675 (registering DOI) - 27 Apr 2024
Abstract
AI plays a pivotal role in predicting plant growth in agricultural contexts and in creating optimized environments for cultivation. However, unlike agriculture, the application of AI in aquaculture is predominantly focused on diagnosing animal conditions and monitoring them for users. This paper introduces [...] Read more.
AI plays a pivotal role in predicting plant growth in agricultural contexts and in creating optimized environments for cultivation. However, unlike agriculture, the application of AI in aquaculture is predominantly focused on diagnosing animal conditions and monitoring them for users. This paper introduces an Automated Fish-feeding System (AFS) based on Convolutional Neural Networks (CNNs) and Gated Recurrent Units (GRUs), aiming to establish an automated system akin to smart farming in the aquaculture sector. The AFS operates by precisely calculating feed rations through two main modules. The Fish Growth Measurement Module (FGMM) utilizes fish data to assess the current growth status of the fish and transmits this information to the Feed Ration Prediction Module (FRPM). The FRPM integrates sensor data from the fish farm, fish growth data, and current feed ration status as time-series data, calculating the increase or decrease rate of ration based on the present fish conditions. This paper automates feed distribution within fish farms through these two modules and verifies the efficiency of automated feed distribution. Simulation results indicate that the FGMM neural network model effectively identifies fish body length with a minor deviation of less than 0.1%, while the FRPM neural network model demonstrates proficiency in predicting ration using a GRU cell with a structured layout of 64 × 48. Full article
(This article belongs to the Special Issue Sustainable Aquaculture Systems)
14 pages, 2905 KiB  
Article
First-Principles Study of Adsorption of CH4 on a Fluorinated Model NiF2 Surface
by Tilen Lindič and Beate Paulus
Materials 2024, 17(9), 2062; https://doi.org/10.3390/ma17092062 (registering DOI) - 27 Apr 2024
Abstract
Electrochemical fluorination on nickel anodes, also known as the Simons’ process, is an important fluorination method used on an industrial scale. Despite its success, the mechanism is still under debate. One of the proposed mechanisms involves higher valent nickel species formed on an [...] Read more.
Electrochemical fluorination on nickel anodes, also known as the Simons’ process, is an important fluorination method used on an industrial scale. Despite its success, the mechanism is still under debate. One of the proposed mechanisms involves higher valent nickel species formed on an anode acting as effective fluorinating agents. Here we report the first attempt to study fluorination by means of first principles investigation. We have identified a possible surface model from the simplest binary nickel fluoride (NiF2). A twice oxidized NiF2(F2) (001) surface exhibits higher valent nickel centers and a fluorination source that can be best characterized as an [F2]- like unit, readily available to aid fluorination. We have studied the adsorption of CH4 and the co-adsorption of CH4 and HF on this surface by means of periodic density functional theory. By the adsorption of CH4, we found two main outcomes on the surface. Unreactive physisorption of CH4 and dissociative chemisorption resulting in the formation of CH3F and HF. The co-adsorption with the HF gave rise to four main outcomes, namely the formation of CH3F, CH2F2, CH3 radical, and also physisorbed CH4. Full article
13 pages, 940 KiB  
Article
Bilateral Asymmetry of Spatiotemporal Running Gait Parameters in U14 Athletes at Different Speeds
by Antonio Cartón-Llorente, Silvia Cardiel-Sánchez, Alejandro Molina-Molina, Andrés Ráfales-Perucha and Alberto Rubio-Peirotén
Sports 2024, 12(5), 117; https://doi.org/10.3390/sports12050117 (registering DOI) - 27 Apr 2024
Abstract
The assessment of leg asymmetries is gaining scientific interest due to its potential impact on performance and injury development. Athletes around puberty exhibit increased gait variability due to a non-established running pattern. This study aims to describe the asymmetries in the spatiotemporal running [...] Read more.
The assessment of leg asymmetries is gaining scientific interest due to its potential impact on performance and injury development. Athletes around puberty exhibit increased gait variability due to a non-established running pattern. This study aims to describe the asymmetries in the spatiotemporal running parameters in developmentally aged athletes. Forty athletes under 14 (U14) (22 females and 18 males) were assessed running on a treadmill at constant speeds of 12 and 14 km·h−1 for 3 min. Step length, step frequency, along with contact (CT) and flight time, both in absolute values and as a percentage of step time, were recorded using a RunScribe sensor attached to the laces of each shoe. U14 runners exhibited high bilateral symmetry in the spatiotemporal parameters of running, with mean asymmetry values (1–5.7%) lower than the intra-limb coefficient of variation (1.7–9.6%). Furthermore, bilateral asymmetries did not vary between the two speeds. An individual-based interpretation of asymmetries identified subjects with consistent asymmetries at both speeds, particularly in terms of CT and contact ratio (%, CT/step time). This study confirms the high symmetry of pubertal runners and paves the way for the application of portable running assessment technology to detect asymmetries on an individual basis. Full article
(This article belongs to the Special Issue Biomechanics and Sports Performances)

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